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6Th Annual Biopartnering North America Chika Hashimoto Gallasus, Inc

6Th Annual Biopartnering North America Chika Hashimoto Gallasus, Inc

6th Annual BioPartnering North America Feb ruary 6 , 2008 | VBCCdVancouver, BC, Canada

Chika Hashimoto Gallasus, Inc.

Gallasus Drug Maker Devel Sales, PartnerinU.S. oped $MN 2004 Drugs originated from ; Prevacid Takeda 1991 4,300 Novartis Pravachol Sankyo 1989 3,865 BMS Number of drugs,g >$500MN worldwide sales in 2004= 21 Levaquin Daiichi 1993 2,525 OrthoMcNeil (166 drugs, total worldwide) Blopress Takeda 1997 2,136 Flomax Astellas 1993 2,111 Boehringer IlhiIngelheim Percentage of sales among LupronDepot Takeda 1984 1,903 Abbott drugs sales >$500MN =13.3% Pariet 1997 1,845 JanssenCilag Aricept Eisai 1999 1,717 Actos Takeda 1999 1,703 EliLilly Biaxin®;Klacid Taisho 1990 1,240 Abbott Prograf Astellas 1993 1,085 Camptosar Yakuruto 1994 1,055 Pfizer Abilify OkOtsuka 2002 829 BMS Reference; Japan Pharmaceutical Manufactures Association Crestor 2003 825 AstraZeneca Gallasus PtP%ercent 8 7 6 5 1998 4 1999 3 1998 and 1999 2 1 0 United States European Japan UiUnion

Source: organization for Economic Co-operation and Development, patent database (September 2004) Science and Engineering Indicators 2006

Gallasus 800

700 Japan

600

500

bers 400 mm Germany United Nu 300 Kingdom

200 Canada Netherlands 100 France

0 19931993 2003 2003

Source: U.S. Patent and Trademark Office, Office of Electronic Information Products, Patent TechnologyGallasus Monitoring Division, special tabulations (2004) Technological Productive capacity

infrastructure Venezuela Venezuela United States United States Thail and Thailand Poland Poland Philippines Philippines Mexico Mexico Malaysia Malaysia Japan Japan Israel Israel Ireland Ireland Indonesia Indonesia India India Hungary Hungary Germany Germany Czech Republic Czech Republic China China Brazil Brazil Argentina Argentina

0.0 20.0 40.0 60.0 80.0 100.0 0.0 20.0 40.0 60.0 80.0 100.0

Reference: Science and Engineering Indicators 2006 Gallasus Skin cell turned into stem cells;

Discovered by Professor Shinya Yamanaka, Kyoto University

Gallasus  Science & Technology • Stem cell • Cellular and molecular biology • Nanotech • Material science

 Academic & Research Institute • University of • Kyyyoto University • Osaka University • Other universities • Government research institutes Gallasus 800

700 Japan Source; JETRO 600

500 s rr 400 German United y

300Numbe Kingdo m 200 Canada Netherl 110000 France ands

0

Gallasus AtAutomo tive 19% Others Electronics 25% 14%

Foods Drugs 9% 12%

Chemicals Manufactur 9% ing 12%

Source: Diamond Co. Ltd. “Corporate tax filing” Gallasus  MbMembers

• Canon • TORAY • ThibToshiba • Mitsubishi Rayon Co. Ltd. • NGK Insulators, Ltd. • DNA Chip Institute • KAZUSA DNA Institute • Etc

Gallasus

Panasonic

Kirin acquired Kyowa Hakko.

Nintendo ; bio- Olympus; I n Vi vo fabric Imaging Gallasus Japan

1hr

1hr

Tokyo N2WldENo2 World Economy &I& Innovati on; All companies are within 1hr air flight reach.

Gallasus  The company's primary business is coconsulting,nsulting, wwithith a focusfocus oonn evaluatingevaluating biotech companies and investment opportunities, finding partners for scientific collaboration and business alliances, an d ana lyz ing mar ke t an d business opportunities in the field of life sciences.

Gallasus  Presented by CChikahika HashimotoHashimoto Gallasus, Inc. [email protected] +1(650)632-4341 +1(650)632-4599 Direc t 303 Twin Dolphin Dr. Suite 600 Redwood City CA 94065 USA

Gallasus