QUICK REFERENCE TO PSYCHOTROPIC MEDICATION® DEVELOPED BY JOHN PRESTON, PSY.D. To the best of our knowledge recommended doses and side effects listed below are accurate. However, this is meant as a general reference only, and should not serve as a guideline for prescribing of medications. Physicians, please check the manufacturer’s product information sheet or the P.D.R. for any changes in dosage schedule or contraindications. (Brand names are registered trademarks.) ANTIDEPRESSANTS Usual Selective Action On NAMES Daily Dosage Neurotransmitters2 Generic Brand Range Sedation ACH1 NE 5-HT DA imipramine Tofranil 150-300 mg mid mid + + + + + 0 desipramine Norpramin 150-300 mg low low +++++ 0 0 amitriptyline Elavil 150-300 mg high high + ++++ 0 nortriptyline Aventyl, Pamelor 75-125 mg mid mid + + + + + 0 protriptyline Vivactil 15-40 mg mid mid ++++ + 0 trimipramine Surmontil3 100-300 mg high mid + + + + 0 doxepin Sinequan, Adapin3 150-300 mg high mid + + + + + 0 maprotiline Ludiomil 150-225 mg high mid +++++ 0 0 amoxapine Asendin 150-400 mg mid low ++++ + 0 trazodone Desyrel 150-400 mg mid none 0 +++++ 0 fluoxetine Prozac5, Sarafem 20-80 mg low none 0 +++++ 0 bupropion-S.R. Wellbutrin-S.R.4,5 150-300 mg low none + + + 0 ++ sertraline Zoloft 50-200 mg low none 0 +++++ 0 paroxetine Paxil 20-50 mg low low + +++++ 0 venlafaxine-X.R. Effexor-X.R.5 75-350 mg low none + + + + + + nefazodone Serzone 100-500 mg mid none + ++++ 0 fluvoxamine Luvox 50-300 mg low low 0 +++++ 0 mirtazapine Remeron 15-45 mg mid mid + + + + + + 0 citalopram Celexa 10-60 mg low none 0 +++++ 0 reboxetine Vestra 4-8 mg low none +++++ 0 0 MAO INHIBITORS phenelzine Nardil 30-90 mg low none + + + + + + +++ tranylcypromine Parnate 20-60 mg low none + + + + + + +++

1ACH: Anticholinergic Side Effects 2NE: Norepinephrine, 5-HT: Serotonin, DA: Dopamine (0 = no effect, + = minimal effect, +++++ = high effect) 3Uncertain, but likely effects 4Atypical antidepressant. Uncertain effects but likely to be a dopamine agonist, and indirect increase in norepinephrine 5Available in standard formulation and time release (XR or SR). Prozac available in 90mg time released/weekly formulation

ANTI-OBSESSIONAL NAMES Generic Brand Dose Range1 Sedation ACH EFFECTS clomipramine Anafranil 150-250 mg high high fluoxetine Prozac1 20-80 mg low none sertraline Zoloft1 50-200 mg low none paroxetine Paxil1 20-60 mg low low fluvoxamine Luvox1 50-300 mg low low citalopram Celexa1 10-60 mg low none 1often higher doses are required to control obsessive-compulsive symptoms than the doses generally used to treat depression.

MOOD STABILIZERS PSYCHO-STIMULANTS 1 NAMES Daily Serum NAMES Generic Brand Dosage Range Level Generic Brand Daily Dosage1 lithium carbonate Eskalith, Lithonate 600-2400 0.6-1.5 methylphenidate Ritalin 5-50 mg carbamazepine Tegretol 600-1600 4-10+ methylphenidate Concerta2 18-54 mg divalproex Depakote 750-1500 50-100 methylphenidate Metadate 5-40 mg gabapentin Neurontin 300-2400 (2) dextroamphetamine Dexedrine 5-40 mg lamotrigine Lamictal 200-500 (2) pemoline Cylert 37.5-112.5 mg topiramate Topamax 50-300 (3) d- and l-amphetamine Adderall 5-40 mg 1Lithium levels are expressed in mEq/l, carbamazepine and valproic acid levels express in mcg/ml. 1Note: Adult Doses. 2Serum monitoring may not necessary 2Sustained release 3 Not yet established © Copyright 2002, John Preston, Psy.D and P.A. Distributors