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Effective Date: Monday, June 07, 2021 Test Updates

In our continuing effort to provide you with the highest quality toxicology laboratory services available, we have compiled important changes regarding a number of tests we perform. Listed below are the types of changes that may be included in this notification, effective Monday, June 07, 2021

Test Changes - Tests that have had changes to the method/ CPT code, units of measurement, scope of analysis, reference comments, or specimen requirements.

Discontinued Tests - Tests being discontinued with alternate testing suggestions.

Please use this information to update your computer systems/records. These changes are important to ensure standardization of our mutual laboratory databases.

If you have any questions about the information contained in this notification, please call our Client Support Department at (866) 522-2206. Thank you for your continued support of NMS Labs and your assistance in implementing these changes.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. NMS Labs does not assume responsibility for billing errors due to reliance on the CPT Codes listed in this document.

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 1 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Test Name Test Method / Specimen Stability Scope Units Reference Discontinue Code Name CPT Code Req. Comments

0751SP , Serum/Plasma • and Metabolites (DUID/DRE), 10036B • Blood (Forensic) (CSA) Cocaine and Metabolites (DUID/DRE), 10036SP • Serum/Plasma (Forensic) (CSA) Cocaine and Metabolites (Qualitative) 10036U • (DUID/DRE), Urine (Forensic) (CSA) Cocaine and Metabolites (Qualitative), 1300ME • Meconium Cocaine and Metabolites - Individual 10136B • (DUID/DRE), Blood (Forensic) (CSA) Cocaine and Metabolites Confirmation 54004B • (DUID/DRE), Blood Cocaine and Metabolites Confirmation 55046U (Drug Impaired Driving/DRE Toxicology), • Urine (CSA) IN/LA Cocaine and Metabolites Confirmation 55262B (Qualitative) (DUID/DRE), Blood • (Forensic) (CSA) Cocaine and Metabolites Confirmation 54004U • (Qualitative) (DUID/DRE), Urine Cocaine and Metabolites Confirmation 5900H • (Qualitative), Hair Cocaine and Metabolites Confirmation 5637ME • (Qualitative), Meconium Cocaine and Metabolites Confirmation 5700ME • (Qualitative), Meconium Cocaine and Metabolites Confirmation, 50014B • Blood Cocaine and Metabolites Confirmation, 5637B • Blood Cocaine and Metabolites Confirmation, 50025B • Blood (CSA) Cocaine and Metabolites Confirmation, 50014FL • Fluid Cocaine and Metabolites Confirmation, 5637FL • Fluid Cocaine and Metabolites Confirmation, 50014SP • Serum/Plasma Cocaine and Metabolites Confirmation, 5637SP • Serum/Plasma Cocaine and Metabolites Confirmation, 50014TI • Tissue Cocaine and Metabolites Confirmation, 5637TI • Tissue Cocaine and Metabolites Confirmation, 50014U • Urine Cocaine and Metabolites Confirmation, 5637U • Urine Cocaine and Metabolites DFC 52510U • Confirmation, Urine (Forensic)

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 2 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Test Name Test Method / Specimen Stability Scope Units Reference Discontinue Code Name CPT Code Req. Comments

1300B Cocaine and Metabolites, Blood • 1300FL Cocaine and Metabolites, Fluid • 1300SP Cocaine and Metabolites, Serum/Plasma • 1300TI Cocaine and Metabolites, Tissue • 1300U Cocaine and Metabolites, Urine • 1303B Cocaine and Products Panel, Blood • Cocaine and Products Panel, 1303SP • Serum/Plasma 1303U Cocaine and Products Panel, Urine • 1439SP Dantrolene, Serum/Plasma • and Metabolite Confirmation 54176B • (DUID/DRE), Blood Fluoxetine and Metabolite Confirmation 54174U • (Qualitative) (DUID/DRE), Urine Fluoxetine and Metabolite Confirmation, 52287B • Blood Fluoxetine and Metabolite Confirmation, 5524B • Blood Fluoxetine and Metabolite Confirmation, 52287FL • Fluid Fluoxetine and Metabolite Confirmation, 52287SP • Serum/Plasma Fluoxetine and Metabolite Confirmation, 5524SP • Serum/Plasma Fluoxetine and Metabolite Confirmation, 52287TI • Tissue Fluoxetine and Metabolite Confirmation, 52287U • Urine Fluoxetine and Metabolite Confirmation, 5524U • Urine Fluoxetine and Metabolite DFC 52511U • Confirmation, Urine (Forensic) 2105B Fluoxetine and Metabolite, Blood • 2105FL Fluoxetine and Metabolite, Fluid • Fluoxetine and Metabolite, 2105SP • Serum/Plasma 2105TI Fluoxetine and Metabolite, Tissue • 2105U Fluoxetine and Metabolite, Urine • and Metabolite Confirmation 54258B • (DUID/DRE), Blood Ketamine and Metabolite Confirmation 54258U • (Qualitative) (DUID/DRE), Urine Ketamine and Metabolite Confirmation, 52058B • Blood

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 3 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Test Name Test Method / Specimen Stability Scope Units Reference Discontinue Code Name CPT Code Req. Comments

Ketamine and Metabolite Confirmation, 5534B • Blood Ketamine and Metabolite Confirmation, 52058FL • Fluid Ketamine and Metabolite Confirmation, 52058SP • Serum/Plasma Ketamine and Metabolite Confirmation, 5534SP • Serum/Plasma Ketamine and Metabolite Confirmation, 52058TI • Tissue Ketamine and Metabolite Confirmation, 52058U • Urine Ketamine and Metabolite Confirmation, 5534U • Urine Ketamine and Metabolite DFC 52512U • Confirmation, Urine (Forensic) 9188B Ketamine and Metabolite Screen, Blood • Ketamine and Metabolite Screen, 9188SP • Serum/Plasma 9188U Ketamine and Metabolite Screen, Urine • 2479B Ketamine and Metabolite, Blood • 2479FL Ketamine and Metabolite, Fluid • 2479SP Ketamine and Metabolite, Serum/Plasma • 2479TI Ketamine and Metabolite, Tissue • 2479U Ketamine and Metabolite, Urine • Novel Psychoactive Substances (NPS) 8756B • Screen 1, Blood - Total 52232U (Conjugated/Unconjugated) • Confirmation, Urine Designer Drugs Confirmation 54340B • (DUID/DRE), Blood Piperazine Designer Drugs Confirmation, 52326B • Blood Piperazine Designer Drugs Confirmation, 52373B • Blood 4150U & B, Urine • 4150B Salvinorin B, Blood • 4150P Salvinorin B, Plasma • meta-Chlorophenylpiperazine (mCPP), 1138B • Blood meta-Chlorophenylpiperazine (mCPP), 1138SP • Serum/Plasma meta-Chlorophenylpiperazine (mCPP), 1138U • Urine

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 4 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes 10036B Cocaine and Metabolites (DUID/DRE), Blood (Forensic) (CSA)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 10036SP Cocaine and Metabolites (DUID/DRE), Serum/Plasma (Forensic) (CSA)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 10036U Cocaine and Metabolites (Qualitative) (DUID/DRE), Urine (Forensic) (CSA)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1300ME Cocaine and Metabolites (Qualitative), Meconium

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene, Meta- Method (CPT Code) Hydroxybenzoylecgonine 10136B Cocaine and Metabolites - Individual (DUID/DRE), Blood (Forensic) (CSA)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 54004B Cocaine and Metabolites Confirmation (DUID/DRE), Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 55046U Cocaine and Metabolites Confirmation (Drug Impaired Driving/DRE Toxicology), Urine (CSA) IN/LA

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 5 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 55262B Cocaine and Metabolites Confirmation (Qualitative) (DUID/DRE), Blood (Forensic) (CSA)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 54004U Cocaine and Metabolites Confirmation (Qualitative) (DUID/DRE), Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 5900H Cocaine and Metabolites Confirmation (Qualitative), Hair

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) GC/MS (None): 5637ME Cocaine and Metabolites Confirmation (Qualitative), Meconium

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene, Meta- Method (CPT Code) Hydroxybenzoylecgonine 5700ME Cocaine and Metabolites Confirmation (Qualitative), Meconium

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene, Meta- Method (CPT Code) Hydroxybenzoylecgonine 50025B Cocaine and Metabolites Confirmation, Blood (CSA)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed.

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 6 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 50014B Cocaine and Metabolites Confirmation, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 5637B Cocaine and Metabolites Confirmation, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 50014FL Cocaine and Metabolites Confirmation, Fluid

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 5637FL Cocaine and Metabolites Confirmation, Fluid

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 50014SP Cocaine and Metabolites Confirmation, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 5637SP Cocaine and Metabolites Confirmation, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 50014TI Cocaine and Metabolites Confirmation, Tissue

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 7 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 5637TI Cocaine and Metabolites Confirmation, Tissue

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 50014U Cocaine and Metabolites Confirmation, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 5637U Cocaine and Metabolites Confirmation, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 52510U Cocaine and Metabolites DFC Confirmation, Urine (Forensic)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1300B Cocaine and Metabolites, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1300FL Cocaine and Metabolites, Fluid

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed.

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 8 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1300SP Cocaine and Metabolites, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1300TI Cocaine and Metabolites, Tissue

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1300U Cocaine and Metabolites, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene Method (CPT Code) 1303B Cocaine and Products Panel, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene, Ecgonine Methyl Ester Method (CPT Code) 1303SP Cocaine and Products Panel, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene, Ecgonine Methyl Ester Method (CPT Code) 1303U Cocaine and Products Panel, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80353): Benzoylecgonine, Cocaine, Cocaethylene, Ecgonine Methyl Ester Method (CPT Code) 1439SP Dantrolene, Serum/Plasma

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 9 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes

Summary of Changes: Reference Comment was changed.

Scope of Analysis: SF (80369): Dantrolene Method (CPT Code) Compound Name Units Reference Comment Dantrolene mcg/mL Spasticity therapeutic range: 0.1 - 0.6 mcg/mL Malignant hyperthermia therapeutic range: 2 - 3 mcg/mL Toxic effects of dantrolene include loss of appetite, constipation, hepatitis, visual disturbances, headache, tachycardia, confusion and nervousness.

54176B Fluoxetine and Metabolite Confirmation (DUID/DRE), Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 54174U Fluoxetine and Metabolite Confirmation (Qualitative) (DUID/DRE), Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 52287B Fluoxetine and Metabolite Confirmation, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 5524B Fluoxetine and Metabolite Confirmation, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 52287FL Fluoxetine and Metabolite Confirmation, Fluid

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code)

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 10 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes 52287SP Fluoxetine and Metabolite Confirmation, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 5524SP Fluoxetine and Metabolite Confirmation, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 52287TI Fluoxetine and Metabolite Confirmation, Tissue

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 52287U Fluoxetine and Metabolite Confirmation, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 5524U Fluoxetine and Metabolite Confirmation, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 52511U Fluoxetine and Metabolite DFC Confirmation, Urine (Forensic)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 2105B Fluoxetine and Metabolite, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed.

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 11 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 2105FL Fluoxetine and Metabolite, Fluid

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 2105SP Fluoxetine and Metabolite, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 2105TI Fluoxetine and Metabolite, Tissue

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 2105U Fluoxetine and Metabolite, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80332): Norfluoxetine, Fluoxetine Method (CPT Code) 54258B Ketamine and Metabolite Confirmation (DUID/DRE), Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 54258U Ketamine and Metabolite Confirmation (Qualitative) (DUID/DRE), Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 52058B Ketamine and Metabolite Confirmation, Blood

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 12 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 5534B Ketamine and Metabolite Confirmation, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 52058FL Ketamine and Metabolite Confirmation, Fluid

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 52058SP Ketamine and Metabolite Confirmation, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 5534SP Ketamine and Metabolite Confirmation, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 52058TI Ketamine and Metabolite Confirmation, Tissue

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 52058U Ketamine and Metabolite Confirmation, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed.

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 13 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 5534U Ketamine and Metabolite Confirmation, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 52512U Ketamine and Metabolite DFC Confirmation, Urine (Forensic)

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 9188B Ketamine and Metabolite Screen, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80307): Norketamine, Ketamine Method (CPT Code) 9188SP Ketamine and Metabolite Screen, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80307): Norketamine, Ketamine Method (CPT Code) 9188U Ketamine and Metabolite Screen, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80307): Norketamine, Ketamine Method (CPT Code) 2479B Ketamine and Metabolite, Blood

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 2479FL Ketamine and Metabolite, Fluid

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 14 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 2479SP Ketamine and Metabolite, Serum/Plasma

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 2479TI Ketamine and Metabolite, Tissue

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 2479U Ketamine and Metabolite, Urine

Summary of Changes: Scope of Analysis was changed. Order of Reporting was changed. Scope of Analysis: GC/MS (80357): Norketamine, Ketamine Method (CPT Code) 8756B Novel Psychoactive Substances (NPS) Screen 1, Blood

Summary of Changes: Specimen Requirements (Special Handling) were changed.

Specimen Requirements: 6 mL Blood Transport Temperature: Frozen Specimen Container: Gray top tube (Sodium Fluoride / Potassium Oxalate), Lavender top tube (EDTA) Light Protection: Not Required Special Handling: Do not freeze Rejection Criteria: Received Room Temperature. Received Refrigerated. Polymer gel separation tube (SST or PST). 54340B Piperazine Designer Drugs Confirmation (DUID/DRE), Blood

Summary of Changes: Specimen Requirements (Special Handling) were changed.

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 15 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Test Changes

Specimen Requirements: 2 mL Blood Transport Temperature: Refrigerated Specimen Container: Lavender top tube (EDTA) Light Protection: Not Required Special Handling: Do not freeze Rejection Criteria: None 52326B Piperazine Designer Drugs Confirmation, Blood

Summary of Changes: Specimen Requirements (Special Handling) were changed.

Specimen Requirements: 2 mL Blood Transport Temperature: Refrigerated Specimen Container: Lavender top tube (EDTA) Light Protection: Not Required Special Handling: Do not freeze Rejection Criteria: None 52373B Piperazine Designer Drugs Confirmation, Blood

Summary of Changes: Specimen Requirements (Special Handling) were changed.

Specimen Requirements: 2 mL Blood Transport Temperature: Refrigerated Specimen Container: Lavender top tube (EDTA) Light Protection: Not Required Special Handling: Do not freeze Rejection Criteria: None

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 16 of 17 Effective Date: Monday, June 07, 2021 Test Updates

Discontinued Tests Test Code Test Name Alternative Test 0751SP Bromocriptine, Serum/Plasma No Alternate Tests Available 52232U Opiates - Total (Conjugated/Unconjugated) 52332U - Opiates - Total Confirmation, Urine (Conjugated/Unconjugated) Confirmation, Urine 4150U Salvinorin A & B, Urine No Alternate Tests Available 4150B Salvinorin B, Blood No Alternate Tests Available 4150P Salvinorin B, Plasma No Alternate Tests Available 1138B meta-Chlorophenylpiperazine (mCPP), Blood 4535B - and mCPP, Blood 1138SP meta-Chlorophenylpiperazine (mCPP), 4535SP - Trazodone and mCPP, Serum/Plasma Serum/Plasma 1138U meta-Chlorophenylpiperazine (mCPP), Urine 4535U - Trazodone and mCPP, Urine

NMS Labs 200 Welsh Rd. Horsham, PA 19044-2208 [email protected] Page 17 of 17