2005.7

(93) 10 (cGMP ) Dr. Linda B. Cottler

1992 1%~1.5%

11%

22%

( )

,

REMEDi 98

94.7.1( )--7.2( )

- 110 2 --

- 2005.7

166 18 63 7

MDMA Flunitrazepam, FM2 Gammahydroxybutyrate GHB (Amineptine) keta- mine Mifepristone Zolpidem Modafinil Butophanol

(Dihydrocodeine) 1961 1971 1988 Chlordiazepoxide Phenobarbital

88 6 2 (Cocaine) 89 4 1 72

89 5 9

89 4 29

89 5 1 89 4 25 88 6 2 92 2 6 89 9 14

89 4 1 92 10 15 93 5 11

89 2 14 92 1 14 16 3 30 3

12 88 12 8 9 2005.7

94 6 10 12,165 35.53 ( )

94 6 10 33,530 77.71 ( )

# * ** 91 1 91 90 4 2005.7

56

19 20

39 89 94 6 10

1 ( ) ( ) ( )

ᛰࠔᆅڋკΟǵᆵчѱࡹ۬ፁғֽࠄ୔ᖄӝዽࢗઠᒤ౛ϐ :5 ԃࡋᆅ

89 94 6 10 5 160 360

5.25 4

93 2005.7

2002 2003 2002

MDMA

Journal of Analytical Toxicology 2002 ,Atlanta,Georgia,USA Analytical Approaches and Analytes Distribution in Antemortem and Postmortem Specimens, Society of Forensic Toxicologist 34th Annual Meeting

--

88 91 92 93

6

91 92 2 7

94 1 87.52% 37.46% 2005.7

93 Benzodiazepines 94 89 93

87,165 258 6,631 747

89 1 93 12 19,790 3,357 6,757 9,676 ( )

692

89 93

25 7

89 93 2005.7

93 9 Methylephedrine Ketamine 5 10 (2) Heroin Morphine Codeine Ketamine Fentanyl Pethidine Methylephedrine Methamphetamine MDMA

(3) 259

2002 NLCP

7

MDMA MDA MDEA 12 REMEDi 98 93 1,022 11 MDMA MDA 721 70.5% 34 10 : MDMA Ketamine 42.3% 93 92

26 38

40

8

93 (1)

(1) ( ) MDMA (2) LC/MS/MS GC/MS 2005.7

Levomethorphan Dextromethorphan Levorphanol Dextrorphan (8) (3)MDMA (4)93 2004 (5) -- Ketamine (9) (6) Ketamine Norketamine Dehydronorketamine 94 2004 (1) (10) LC/MS/MS (2) Ketamine Levomethorphan Dextromethorphan Levorphanol Dextrorphan 93 (3) - Methadone (11) (alcohol) (4) ( ) 93 (5) 94

(1)

MDMA KETAMINE 84 24: 3 (2005) (2) MDMA 87 7 94 63 2 (3)Chiareiy Liu, Jih-Heng Li, Wen-Ing Tsay and Jui 40 Hsu , Drug use and profile of individuals arrested on 6 2 drug-related charges in Taiwan, Journal of Food and 3 Drug Analysis, 13, 101-106 (2005). (4)Min-Kun Huang, Yu-Shan Dai, Choung-Huei Lee, Chiareiy Liu, Wen-Ing Tsay, Jih-Heng Li Performance Characteristics of DRI, CEDIA, and REMEDi Systems for Preliminary Tests of Amphetamines and Opiates in Human Urine. 90 12 Accepted April 21, 2005 by Journal of Analytical 91 1 1 Toxicology. (5) 91 Drug Profile of Urine Specimen from Arrestees in Taiwan, 2005 92 AAFS 51 (6)Chiareiy Liu, Wen-Ing Tsay, Choung-huei Lee and 130 9 Jih-Heng Li:Cutoff Concentration of Ketamine and ( ) Metabolite in Urine was Set in Taiwan for Certified Laboratories, 2005 AAFS (7) REMEDi FM2 7-aminofluni- trazepam 2004 2005.7

93 12,232 ( ) Benzodiazepines MDMA ( ) 93 ( ) MDMA FM2 (Club Drugs)

(93) ---

1.5% 93 (94)

(Baseline Data)

(93) 10 Dr. Linda B. Cottler

MDMA( Ecstasy)

10

MDMA

MDMA 88 7 1

90 2005.7

(5)

B C

(1) 2001 2003

(2)

(3) 249

(4)

(1)86

2002 93

(2)

11

(3) (1)

FM2 ! (4) PUB KTV T 2005.7

) (25 ) 25 (2) 100 OK 750 7-11 3,480 45 631 123 19 40 364 (3) 2002 2003 LED

2004

(4) SAY NO

KTV (5)

2002 92

93

RU486 FM2 20

TVBS 92 12 15 1 15

12 94 6 26 ( ) (25 ) (25 ) (61 ) (215 ) 88 9 18 89 26 90 36 20 (17 2005.7

91 17 92 31 93 54

(cGMP )

93 10 88 89 90 91 cGMP 92 93 / 89 6

93 6 18 9 1 7 1 20

10%

20 0.2 0.4 50 10 20

cGMP

13

( http://www.nbcd.gov.tw/company/companyforIE.asp) 2005.7

( )

94 5 6 0940510109

( )

( 2 1 )

14 (rescue dose)