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Acetolactate Synthase, ] 737-740 Acrylyl-Coa Reductase

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Acetolactate Synthase, ] 737-740 Acrylyl-Coa Reductase SUBJECT INDEX Acetolactate synthase, ]D-amin o acid oxidase, 91 737-740 methylation, 102 Acrylyl-CoA reductase, ENDOR, 289 467-470 resonance raman, 291-294 Acyl CoA dehydrogenase role of arginines, 295-299 mechanism, 385-401,43 9-442 methylation of histidine, general, 389, 443, 447,451 301-304 reaction with deuterated Stoichiometry of self- substrates, 390 association, 305-308 short chain, 417,421,435, sequence homology with L- 439 lactate oxidase, 333 suicide inactivation by modification with 8-azido- propionyl CoA, 421 FAD, 753 medium chain, 435,439 complex with 4 thio-FAD, 770 long chain, 435, 439 Amino acid sequence, 95-109, 2-methyl-branched 111-124 chain,isovaleryl-CoA 435 E.coli glutathione reductase, inhibition by 2-alkynoyl- 118-122,132-135 CoA derivatives, 443 lipoamide dehydrogenase, inhibition by methylene- 118-122, 153-156,157-160 cyclopropyl-acetyl-CoA ferredoxin-NADP+ reductase, 447-450 169-172, 173 Acyl CoA oxidase, 446,451 dimethylglycine dehydrogenase, Adrenodoxin, 485 216 Adrenodoxin reductase sarcosine dehydrogenase, 216 471-484, 485-488 NADii-cytochrome bg reductase, Alcohol oxidase, 569-572 221-224 Aldehyde oxidase succinate dehydrogenase, 225-228 e.p.r. studies, 325-330 fumarate reductase, 225-228 N-5alkyl flavin, 418,421 trimethylamine dehydrogenase, Alloxazines, 17-20 234, 240 7-cyano, 17 flavodoxin, 253-254 6-monomethyl, 2 0 L-lactate oxidase, 331-334 9-monomethyl, 2 0 bacterial luciferase, 351 photoreduction, 18 riboflavin synthase, 380 band shape analysis, 19 laser flash photolysis, 25-28 914 N6-(6-aminohexyl) FAD Charge transfer complexes, 22 labelling of drugs Old Yellow Enzyme, 183-189, proteins,hormones for 191-210, 211 immunoassay, 899-902 acyl-CoA dehydrogenase, 439, Anacystis nidulans, 253 443-446, 451-454 Apoenzyme Reactivation Chemical modification, see Immunoassay system protein modification (ARIS), 899, 903 Chlorella vulgaris Arthrobacter oxidans 807- NADH-nitrate reductase, 810, 810-814, 815-818 247-250 8-Azidoflavins, 751-754 8-chloroflavin Azotobacter vinelandii glutathione reductase, 756 lipoamide dehydrogenase, electron transferring flavo- NMR, 143-146 protein, 761 X-ray studies on lipoamide dehydrogenase, 14 7 phenol hydroxylase, 768 mobility of lipoamide luciferase, 786 dehydrogenase, 149-152 CIEEL pathway, 39, 669-672 photomodification of Circular dichroism flavodoxin, 262 Old Yellow Enzyme, 183-189, flavodoxin redox 201 potentials, 495 covalent complex of ferre- Bacillus subtilis doxin and ferredoxin : NADP riboflavin synthase, reductase, 179-182 375-378, 379-382 Clostridium kluyveri Bifunctional reagent photomodification of arsenoxide and E.coli flavodoxin, 262 lipoamide dehydrogenase, orange-red protein, 267 157-160 acrylyl-CoA reductase, 467 Biosynthesis of lipoamide dehydrogenase, 803-806 Clostridium MP Butyryl CoA dehydrogenase, comparison of flavodoxin 396-403 structure with A.nidulans flavodoxin, 256-258 oxygen reactivity, 413-416 photomodification of flavo- binding of acetoacetyl doxin, 262 thioesters, 407-409 flavodoxin redox potentials removal of CoA, 407 493 regreening with CoA p-Cresol methylhydroxylase, persulphide, 407, 409 643-656 Cellobiose oxidoreductases, Cyclohexanone monooxygenase 679-682 608, 611 915 Cyclophane, 21-2 5 oxidant stress, 849-859 Cytochrome b,, see antioxidant capacity, 849- flavocytochrome b2 859 Cytochrome b245, 599-604 glutathione reductase, 849- 859 Cytochrome b5 reductase, 221-224 carmustine (BCNU) 853-859 1-deaza flavin HECNU (1-(2-chloroethyl-)1- nitroso-3-(2-hydroxyethyl) glutathione reductase,758 urea) 853-859 5-deaza flavin, 723-735 malaria, 853-859 2-desoxy-2-dihydroflavin, Electron Nuclear Double 12, 14,15 Resonance (ENDOR) Desulfovibrio vulgaris flavin radicals, 33-36 15 13c and N NMR of flavoproteins, 289-290 flavodoxin, 269-272 Electron paramagnetic flavodoxin redox resonance (e.p.r) potentials, 495 molybdenum cofactor, 323-324 2,5-diketocamphane mono- oxygenase, 343-344 xanthine oxidase, 325-330, 691-694 Dimethyl glycine dehydro- genase, 215-216 aldehyde oxidase, 325 DNA photolyase, 861-874 N-5-adduct of short chain acyl-CoA dehydrogenase, blue radical, 862-868 421-433 second chromophore, 862- 864, 866 succinate dehydrogenase, 550, 551-554 activity, 868-871 Mo(V), 691-694 Domain,flavin Molybdenum centres, 707 glutathione reductase, Electron spin resonance 83, 90 (e.s.r) in NADH : nitrate reductase, 247-250 flavin radicals, 33 Electron transferring flavo glycolate oxidase, 285 protein, 455-458, 459-462 Domain, membrane-binding, 224 Paracoccus denitrificans 455-458, 459-462 Domain, pyridine nucleo- correlation of redox state tide, 98 and dehydrogenation of oct- Domain structure anoyl-CoA, 463-466 trimethylamine dehydro- flavin analogue studies, genase, 236-238 761-764 Drug research, 847-859 Electron transferring flavo- protein : CoQ reductase OSVAC processes, 849-859 916 Paracoccus denitrificans, 8-hydroxy, 723,681 455-458, 459-462 8a-imidazole, 61-66 Escherichia coli high performance liquid gene sequencing, 111-124, chromatography, 72 125-137, 225-228 isomerisation, 71-74 lipoamide dehydrogenase, neko, 75-77 157-160 7a-hydroxy, 75-77, 819-832 succinate dehydrogenase, 225-228, 551-554 8a-hydroxy, 75,819-832 fumarate reductase, deficiency in mammals, 225-228, 551-554 842-844 DNA photolyase, 861-874 catabolism and excretion in mammals, 840-842 Factor 420, 723-735 interconversion in mammals, FAD-theophylline conjugate 837-840 synthesis and use in immuno- digestion, absorption, assay, 899, 903 metabolic fate, 833-834 Ferredoxin transport in circulation, complex with ferredoxin- 834-836 NADP+ reductase,175-178, cell uptake and metabolic 179-182 trapping, 836-837 Ferredoxin-NADP+ reductase, metabolism, 819-832,833-846 169-172, 173 Flavin electrodes, 893-896 complex with ferredoxin, 175-178, 179-182 Flavin-oxygen reaction, 45-55, 59, 111 transient kinetics, 489-492 Flavin radicals, 33-36,45,57 Flavin complexes with sulphydryl hydrogen bond, 5 compounds, 67-70 orbital structure, 6,10,13,14 Flavins photoelectron spectra, 8,9 TT — TT interactions, 21-25 theoretical calculations, second derivative optical 6,7,11,13 absorption spectroscopy,196 4a- and 10a- adducts in medicine, 848 29,32,37-40 as labels in immunoassays, photoadduct formation, 41-44 899-902 photoinactivation, 41-44 Flavocytochrome b2, 513-529 flash photolysis 41-44 polarized absorption 4a-hydroxy, 54 spectra, 251 4a-hydroperoxy, 46 elimination, 514 6-hydroxy-, 681,757,777 intermolecular hydrogen transfer, 519, 529 917 acetylenic inhibitors, 527 glutathione reductase, 118- modulation of redox 127, 125-135 potentials, 531-534 mercuric reductase, 166 pulse radiolysis, 539-542 bacterial luciferase, 345-350 Flavodoxin 6-hydroxy-D-nicotine oxidase FMN : protein interactions, 815-818 253-259 K-pneumoniae flavodoxin, 8 75 Anacystis nidulans, 253 Glucose oxidase Semiquinone map, 255 ENDOR, 289 photochemical modifi- pulse radiolysis, 573-576 cation, 261 oxidation-reduction in fuel cell, 879-892 potential, 258, 494-496 apoenzyme in immunoassay 13 15 x C and N NMR 899, 903 Glutamate synthase modification with 8-azido- FMN, 752 enzyme from Azospirillum cloning of nifF gene from brasilense, 559-564 Klebsiella pneumoniae, 875 Glutaryl-CoA dehydrogenase Fluorescence lifetime, purification and charac- in vapour phase, 5 terisation, 455 8-Fluoro-FAD, 767 Glutathione reductase, 81-93, 97, 139-142, 143-146, 501- Fumarate reductase 504, 505-508, 755-759,848-853 E.coli gene sequence, 115 binding mode and action of structural comparison with FAD in, 81-9 3 succinate dehydrogenase, FAD pyrophosphate stabiliza- 225-228 tion, 83 Enterobacter agglomerans FAD conformation, 8 5 NADH-dependent enzyme, FAD-NADPH interaction, 87 469-470 pathway of Hs from NADPH, 88 e.s.r. studies, 551-554 E.coli gene sequence, 118-122, role of anchor peptides, 132-135 555-558 correlation of X-ray studies Gene cloning and sequence, with kinetic data, 139-142 111-124, 125-137 13C-NMR, 143-146 E.coli flavoprotein genes 113 reaction with 2,4,6-trini- trobenzene sulphonate,501-504 succinate dehydrogenase, 115 multifunctionality, 505-508 fumarate reductase, 115 replacement of FAD with lipoamide dehydrogenase, analogues, 755-759 118-122 918 inhibitors as antimalarial in glutathione reductase, 757 drugs, 853-859 in p-hydroxybenzoate hydroxyl Glycolate oxidase ase, 777-780 X-ray structure, 277-288 8-Hydroxyflavins, 723-735 oxidation-reduction in eellobiose dehydrogenase, properties, 565-568 681 Hansenula anomala 7a- and 8ahydroxy flavins flavocytochrome b?,531-534 formation in mammals,819-832 535-538,539-542 6-Hydroxy-D-nicotine oxidase High performance licjuid 14 chromatography, 73 relationship of C-riboflavi -labelled proteins in Arthro- Hydrogenase, 726,879-892 bacter oxidans, 807-810 Hydrogen bonding, 3-16 electron immunochemical local -zation in Arthrobacter oxi- influence on orbital dans, 811-813 structure, 6,10,13,14 4a-hydroperoxyflavin gene cloning, 815-818 46 ,573 ,60 6-618,619-622 , Hypertension, 848 657-667 8a-imidazole flavins 4-hydroxy-7-azapteridine effect of pH on redox proper- reaction with xanthine ties, 61-66 oxidase, 687-690 Immobilised FAD, 893-896 p-Hydroxybenzoate hydroxylase 51, 335,613,635,770,773, Immunoassay, FAD labelled, 777,781 899, 903 NADPH-binding, 62 3-626 Iso-flavins 770,773-776 general acyl-CoA dehydro- 4-thio-FAD derivative genase, 448 770,773-776 Klebsiella pneumoniae 6-hydroxy-FAD derivative, flavodoxin, 875 reaction with oxygen, 777-780 L-lactate oxidase effect of pH and modifi- amino acid sequence, 331-334 cations in position 8 dehydrohalogenation, 517 on oxidation of reduced enzyme, 781-784
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