HNRNPD Polyclonal Antibody

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HNRNPD polyclonal antibody Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear Catalog Number: PAB18391 ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with Regulatory Status: For research use only (RUO) heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and Product Description: Rabbit polyclonal antibody raised appear to influence pre-mRNA processing and other against synthetic peptide of HNRNPD. aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to Immunogen: A synthetic peptide corresponding to shuttle between the nucleus and the cytoplasm. The residues surrounding S83 of human HNRNPD. hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two Host: Rabbit repeats of quasi-RRM domains that bind to RNAs. It Reactivity: Human,Mouse,Rat localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Applications: ELISA, IF, IHC-P, WB-Ce Alternative splicing of this gene results in four transcript (See our web site product page for detailed applications variants. [provided by RefSeq] information) References: Protocols: See our web site at 1. A mechanism for translationally coupled mRNA http://www.abnova.com/support/protocols.asp or product turnover: interaction between the poly(A) tail and a c-fos page for detailed protocols RNA coding determinant via a protein complex. Grosset C, Chen CY, Xu N, Sonenberg N, Jacquemin-Sablon H, Specificity: This antibody is specific to HNRNPD. Shyu AB. Cell. 2000 Sep 29;103(1):29-40. Form: Liquid Purification: Affinity purification Concentration: 1 mg/mL Recommend Usage: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:20000) The optimal working dilution should be determined by the end user. Storage Buffer: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing. Entrez GeneID: 3184 Gene Symbol: HNRNPD Gene Alias: AUF1, AUF1A, HNRPD, P37, hnRNPD0 Page 1/1 Powered by TCPDF (www.tcpdf.org).

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AF0033-Phospho-Hnrpd (Ser83) Antibody
Affinity Biosciences website:www.affbiotech.com order:[email protected] Phospho-hnRPD (Ser83) Antibody Cat.#: AF0033 Concn.: 1mg/ml Mol.Wt.: 38kDa Size: 100ul,200ul Source: Rabbit Clonality: Polyclonal Application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000 *The optimal dilutions should be determined by the end user. Reactivity: Human,Mouse,Rat Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- peptide and non-phospho-peptide affinity columns. Specificity: Phospho-hnRPD (Ser83) Antibody detects endogenous levels of hnRPD only when phosphorylated at Sersine 83. Immunogen: A synthesized peptide derived from human hnRPD around the phosphorylation site of Ser83. Uniprot: Q14103 Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. Storage Condition and Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM Buffer: NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
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Supplemental Material For
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Gene Name Gene Symbol Q-Value
Supplemental Table S1. Genes differentially expressed in ovary of old rhesus monkeys vs. young and middle-age monkeys Old vs. Young Old vs. Middle-age q-value* Fold Differentially q-value Fold Differentiall Gene Name Gene Symbol RefSeq Transcript ID (%) Change expressed (%) Change y expressed Similar to Cofilin-1 (Cofilin,LOC721819 non-muscle4.495104 isoform) 26.8915 + - - - XM_001096328XR_014660 /// XM_001096451 /// melanocortin 2 receptorMRAP accessory protein4.646275 22.8616 + - - - XM_001096562 /// XM_001096665 /// XM_001096774 chitinase 1 (chitotriosidase)CHIT1 3.396112 12.2749 + - - - XM_001102929 /// XM_001103012 chromosome 4 openMGARP reading frame 49 ortholog4.7194 7.4128 + - - - XM_001087713 similar to WNT1-inducibleLOC717872 signaling pathway3.431917 protein 7.00412 precursor (WISP-2)+ (Connective- tissue- growth factor-like- protein)XM_001109859 (CTGF-L) (Connective tissue growth factor-related protein 58) potassium voltage-gatedKCNB1 channel, Shab-related1.590142 subfamily,5.8293 member+ 1 - - - XM_001098678 Similar to peptidylprolylLOC707078 isomerase A isoform2.453362 1 5.2929 + - - - XR_011674 matrix metallopeptidaseMMP9 9 (gelatinase 2.735892B, 92kDa gelatinase,5.2734 92kDa +type IV collagenase)- - - XM_001104871 similar to mannan-bindingLOC708206 lectin serine4.257852 protease 1 isoform5.1997 2 precursor+ - - - XR_012871 Similar to profilin 1 LOC706963 4.257852 5.0668 + - - - XR_011653 XM_001083742 /// XM_001083847 /// similar to acyl-CoA synthetaseLOC694871 long-chain4.495104 family member4.5633 1 + - - - XM_001083961
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