Anti-HNRNPDL Monoclonal Antibody (DCABH- 200703) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

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Anti-HNRNPDL monoclonal antibody (DCABH- 200703) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. Immunogen A synthetic peptide of human HNRPDL is used for rabbit immunization. Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A Conjugate Unconjugated Applications WB, ELISA Size 1 mg Buffer In 1x PBS, pH 7.4 Preservative None Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. GENE INFORMATION 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene Name HNRNPDL heterogeneous nuclear ribonucleoprotein D-like [ Homo sapiens (human) ] Official Symbol HNRNPDL Synonyms HNRNPDL; heterogeneous nuclear ribonucleoprotein D-like; HNRNP; JKTBP; HNRPDL; JKTBP2; laAUF1; hnRNP DL; hnRNP D-like; protein laAUF1; JKT41-binding protein; AU-rich element RNA-binding factor; A+U-rich element RNA binding factor; Entrez Gene ID 9987 Protein Refseq NP_001193929 UniProt ID A0A087WUK2 Chromosome Location 4q21.22 Function DNA binding; double-stranded DNA binding; nucleotide binding; poly(A) RNA binding; poly(A) binding; poly(G) binding; single-stranded DNA binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.

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Supplemental Material For
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