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Digestive System PDF Digestive System 1. General organization of the internal organs 2. Digestive system – overview 3. Anterior digestive tract 4. Gastrointestinal tract 5. Rectoanal region 6. Hepatobiliary system 7. Peritoneum SPLANCHNOLOGY Internal organs of human body Internal organs – viscera (splanchna): organs of the digestive, respiratory and urogenital systems located primarily in the thoracic and abdominal cavities functions – organs of vegetative state (vegetative organs) metabolism reproduction structural and functional differentiation hollow organs (tube or pouch) or parenchymal organs Prof. Dr. Nikolai Lazarov 2 SPLANCHNOLOGY Internal organs Digestive system: from cranial to caudal end of the body, mostly in the abdominal cavity Respiratory system: mainly in the thoracic cavity Urogenital system: lower part of the abdominal cavity and in the pelvis Prof. Dr. Nikolai Lazarov 3 SPLANCHNOLOGY Tissue structure of the internal organs Main tissues: epithelial tissue – functionally distinct tissue smooth muscle tissue connective tissue: loose connective tissue dense connective tissue reticular tissue cartilage tissue nervous tissue: nerve cells (neurons) autonomic nerves sensory receptors Prof. Dr. Nikolai Lazarov 4 SPLANCHNOLOGY General structure of hollow organs mucosa, tunica mucosa: lamina epithelialis – covering epithelium lamina propria – loose connective tissue blood and lymph vessels lymph follicles (MALT, GALT, BALT) elastic fibers, nerves and nerve structures mucosal glands – in stomach and gut lamina muscularis mucosae – smooth muscle (membrana elastica) tela submucosa blood vessels submucosal plexus (plexus of Meissner) glands – in esophagus and duodenum tunica muscularis inner circular layer myenteric plexus (plexus of Auerbach) outer longitudinal layer tunica serosa (adventitia) Prof. Dr. Nikolai Lazarov 5 SPLANCHNOLOGY General structure of parenchymal organs Parenchyma vs. Stroma Solid organs, organa solida: epithelial tissue – parenchyma connective tissue – stroma blood and lymph vessels nerve structures Structure principle: structural units lobules, segments, lobes fibrous capsule adventitia or serosa Main functions: secretion and excretion gas exchange formation of sex cells Representatives: liver, pancreas kidney, spleen ovary, glands Prof. Dr. Nikolai Lazarov 6 SPLANCHNOLOGY Digestive system Digestion: mechanical breakdown of food chemical breakdown – enzymes traveling down of the bolus (peristalsis) absorption of the chyme elimination of waste material (defecation) Prof. Dr. Nikolai Lazarov 7 SPLANCHNOLOGY Digestive system Digestive system, systema digestorium, apparatus digestorius: alimentary canal – length 9 m mouth anus accessory digestive glands: salivary glands liver pancreas Prof. Dr. Nikolai Lazarov 8 SPLANCHNOLOGY Alimentary canal Anterior part: mouth and oral cavity throat, pharynx gullet (esophagus) Middle part – GI tract: stomach small intestine Posterior (terminal) part: large intestine, incl. rectum and anus Prof. Dr. Nikolai Lazarov 9 SPLANCHNOLOGY Oral cavity, cavitas oris Cavitas (cavum) oris Gr. stoma, stomatos: in the facial region of the head rima oris isthmus faucium Parts of the oral cavity: oral vestibule, vestibulum oris oral cavity proper, cavitas oris propria boundaries o gums and teeth o hard palate o part of the soft palate o diaphragma oris content o tongue o teeth fauces – the troat Prof. Dr. Nikolai Lazarov 10 SPLANCHNOLOGY Lips, labia oris Macroscopic anatomy: oral fissure angle of mouth labial frenulum Upper lip, labium superius Lower lip, labium inferius Structure – orbicularis oris muscle: cutaneous portion – hairy skin marginal (red) portion mucosa– stratified squamous epithelium Prof. Dr. Nikolai Lazarov 11 SPLANCHNOLOGY Cheeks, buccae Structure – two membranous walls: enclose the mouth laterally similar to lips structure skin muscle layer – buccinator muscle subcutaneous fat tissue, – buccal fat pad (Bichat) buccal mucosa Prof. Dr. Nikolai Lazarov 12 SPLANCHNOLOGY Palate Palate, palatum: separates the oral cavity from the nasal cavity palatum durum palatum molle Hard (bone) palate, palatum durum (osseum) – anterior ⅔: processus palatinus maxillae lamina horizontalis ossis palatini transverse palatal ridges Soft palate, palatum molle – posterior ⅓ velum palatini with uvula pharyngopalatine arch skeletal muscle glandular tissue, no bone Prof. Dr. Nikolai Lazarov 13 SPLANCHNOLOGY Gums, gingivae Gums, gingivae: pars fixa pars libera s. marginalis Macroscopic anatomy: gingival margin gingival sulcus papilla gingivalis (interdentalis) vestibular oral Microscopic anatomy: lamina epithelialis stratified squamous nonkeratinized epithelium lamina propria – papillae abundant blood supply rich innervation Prof. Dr. Nikolai Lazarov 14 SPLANCHNOLOGY Teeth, dentes Teeth, dentes (Gr. odus, odontos ): mechanical breakdown (chew) of food help in phonation derivatives of oral mucosa Characteristics of human dentition: close contact between teeth heterodont – teeth differ morphologically diphyodont – two successions of teeth in a process of evolution – reduction in number Prof. Dr. Nikolai Lazarov 15 SPLANCHNOLOGY Human dentition Permanent teeth, dentes permanentes: 32 teeth into two symmetrical halves upper dental arch , arcus dentalis superior lower dental arch , arcus dentalis inferior anatomical and functional groups: incisors, dentes incisivi canine (dogteeth), dentes canini premolars, dentes premolares molars, dentes molares Prof. Dr. Nikolai Lazarov 16 SPLANCHNOLOGY Human dentition Deciduous (milk) teeth, dentes decidui: the first set of teeth in the growth development of humans 20 teeth into two symmetrical halves distinguishing features (traits): similar morphology but smaller in size slightly blue tone of enamel shorter roots wider root canals and cavity anatomical and functional groups: incisors, dentes incisivi - 2 canine teeth, dentes canini – 1 molars, dentes molares – 2 Prof. Dr. Nikolai Lazarov 17 SPLANCHNOLOGY Basic tooth structure Principal parts of a tooth: tooth crown, corona dentis – surfaces margo incisialis (incisivus) – incisors facies occlusalis (masticatoria) – premolars and molars o tuberculum dentale (cuspis dentalis) facies vestibularis (labialis, buccalis) facies lingualis facies contactus (mesialis et distalis) anatomical vs. clinical crown tooth neck, cervix dentis root, radix dentis – in dental alveolus apex radicis dentis cavity – cavitas dentis (pulparis) cavitas coronae canalis radicis dentis tooth pulp, pulpa dentis pulpa coronalis pulpa radicularis Prof. Dr. Nikolai Lazarov 18 SPLANCHNOLOGY Tongue, lingua (Gr. glossa) Parts of the tongue: body, corpus linguae apex linguae root of tongue, radix linguae divided by the sulcus terminalis Surface anatomy of the tongue: upper surface, dorsum linguae pars presulcalis (anterior, oralis) pars postsulcalis (posterior, pharyngealis) sulcus terminalis foramen cecum sulcus medianus linguae lower, facies inferior linguae plica fimbriata frenulum linguae caruncula sublingualis plica sublingualis margin of the tongue, margo linguae Prof. Dr. Nikolai Lazarov 19 SPLANCHNOLOGY Papillae of the tongue Papillae linguales – 4 distinct types: papillae filiformes (conicae) papillae fungiformes papillae vallatae papillae foliatae Prof. Dr. Nikolai Lazarov 20 SPLANCHNOLOGY Taste perception taste buds, caliculi (gemmae) gustatorii – 2000-9000: vallate papillae – most numerous, plentiful in the posterior ⅓ of tongue fungiform and foliate papillae soft palate, epiglottis and pharynx reduction in number (up to ⅓) with age our sense of taste can and do change over time! Prof. Dr. Nikolai Lazarov 21 SPLANCHNOLOGY Glands of the tongue Glandulae linguales – minor salivary glands: mixed (seromucous) glands – near the tip anterior lingual (Nuhn’s) glands serous glands – in the vallate papillae gustatory (von Ebner’s) glands mucous glands – in the tongue root posterior lingual (Weber) glands Prof. Dr. Nikolai Lazarov 22 SPLANCHNOLOGY Lingual tonsil Tonsilla lingualis: small, rounded mass of lymphoid tissue in the posterior ⅓ of the tongue tonsillar papillae, tonsillar crypts Weber’s salivary glands covered with stratified squamous epithelium Prof. Dr. Nikolai Lazarov 23 SPLANCHNOLOGY Muscles of the tongue Skeletal (extrinsic) lingual muscles – move the tongue: m. genioglossus – most well developed m. hyoglossus m. styloglossus m. palatoglossus m. chondroglossus – inconstant Prof. Dr. Nikolai Lazarov 24 SPLANCHNOLOGY Muscles of the tongue Proper (instrinsic) lingual muscles – alter its shape: m. longitudinalis superior m. longitudinalis inferior m. transversus linguae m. verticalis linguae Prof. Dr. Nikolai Lazarov 25 SPLANCHNOLOGY Salivary glands Small salivary glands, glandulae salivariae minores: mixed glands: labial buccal molar anterior lingual glands (Nuhn) serous glands: von Ebner ’s glands in the tongue mucous glands: palatine glands posterior lingual glands (Weber) Prof. Dr. Nikolai Lazarov 26 SPLANCHNOLOGY Salivary glands Large salivary glands, glandulae salivariae majores: Parotid gland, glandula parotidea (parotis) Submandibular gland, glandula submandibularis Sublingual gland, glandula submandibularis Prof. Dr. Nikolai Lazarov 27 SPLANCHNOLOGY Fauces, fauces Isthmus faucium Fauces: velum palatinum – superiorly uvula palatina palatoglossal arch palatopharyngeal arch Prof. Dr. Nikolai
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