International Journal of Applied Ayurved Research ISSN: 2347- 6362 RASONA (ALLIUM SATIVUM) A WONDER DRUG FROM ANCIENT TO MODERN AND KITCHEN TO MEDICINE 1Usha Patil 2Rajendra H.M. 3Geetha Kumar 1Assistant professor, dept of Dravyaguna Sri. Jayendra Saraswathi College and Hospital, Nazarathpet, Chennai. 2Assistant professor, dept of Dravyaguna, Sri. Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai. 3Assistant professor dept of rachana shareera. Sri. Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai. ABSTRACT: Lasoona is a most potent herb used in many conditions mainly used as a rasayana in Vatavyadhi, amavata ec. The plant consists of five rasas except lavana . It has many synonyms which indicates its morphology,properties, and taste. It not only posses medicinal values it posses nutritive value also. Many acharyas used this potent herb in many formulations like lashoonadi vati,lashoona ksheera paka etc. this article describes its morphology,synonyms,habitat,uses,dose,indication,contraindication,recent research work etc. Key Words: Lasoona , Allium sativum Linn, Garlic. INTRODUCTION: Allium sativum Linn bottom by tubular leaf sheath6. Cultivated is an important and well known herb throughout India mainly in Punjab, belong to family Liliacea commonly called Karnataka, Tamil Nadu, Andra Pradesh, as garlic in English, mainly used as a spice Uttar Pradesh and Gujrat7 The botanical worldwide.1 Lashoona means rasa oona2 name of the garlic is Allium Sativum Linn9 ‘devoid of amla rasa’ (sour). In kashyapa Contemporary literature : Garlic belong there is a chapter called lashoona to onion family is a native of central Asia adhyaya, which contains many with recorded usage of 7000 years for its references and elaborate explanation on culinary and medicinal properties, the origin, method of administration, presently grown in Asia, Africa and benefits etc of lashoona3. In Caraka Europe. Currently India is the second Samhita and Susruta Samhita lashoona is largest producer of garlic in the world mainly advocated in vataja disorders in the followed by China. form of rasayana4. The significance of the Types: In Kashyapa Samhita two types of drug is very well mentioned in several garlic has been mentioned depending upon classics and pharmacopeias. the distribution. The one which grows in ORIGIN AND HABITAT:According to the hills ie is girija is like a nectar used by ancient literatures, Lord while the gods, physicians and for the taking the Amrutha from the heaven, few achievements and other which grows in the drops of amrutha fallen on the earth by plains is ksetraja10 these drops lashoona takes its origin5. A In Nighantus two types of lashoona is scapigerous foetid perennial herb with mentioned one is lasuna (Allium sativum) underground compound bulb covered over and the other one is maha kanda /grnjana by outer white thin scales and with simple, (Allium ascalonium Linn)11 smooth, round stem, surrounded at the [Usha Patil etal: Rasona (Allium sativum) A Wonder Drug from Ancient to Modern and Kitchen to Medicine]

Synonyms : D.Ni.12 R.Ni13 K.Ni14 Sh.Ni15 Bha,Ni16 Aristha Aristha - Aristha Aristha Mlecchakanda Mlecchakanda Mlecchakanda Mlecchakanda Mlecchakanda Mahoushada Mahoushada Mahoushda Mahoushda Yavanestha Maha kanda Bhootaghna Mahakanda Sweta kanda Mahoushda Grunjana Ugragandha Ugragandha Vatari Ugragandha Deerga patraka Sheetamardaka Yavanestha Deerga patraka Deerga patraka Vernacular names:Garlic (English), lasan Bhavaprakasha describes the (Hindi), Thum (Sind), sir (Persian), presence of rasa in different parts of the shunam (Gujrathi), velluii (Telugu), plant like, moola (root) patra (leaf), naala vallapundu (Tamil), vellulli (Malayalam), (stem) kashaya naalagra (tip of the stem) bellulli (Kannada), rasun (Bengali).17 and beeja (seed).20 The drug is used as Botanical description18:A bulbous ‘rasayana’ (meaning circulation of “rasa”- herb,60cm high. Leaves – long, flat, acute, the nutrient in ). The ancient sheathing the lower half of stem. Indian physician, kashyapa described that, Flowering scape slender, smooth, shining; lashoona is born from nectar hence the spathes long, beaked, flowers – small, rasayana property. Rasayana properties white, prolonged into leafy points . are, increased life span, promotion of Nutritive composition: The drug contains intelligence, improved memory, freedom carbohydrates (arabinose, galactose), from diseases, strengthens the teeth, flesh, vitamins (folic acid, niacin, thiamine, Vit. nails, beard and hair. The drug clears the c), amino acids (arginine, asparagic acid, channels (srotas), produces sukra (sperm methionine), enzymes (allinase), volatile and spermatic fluid) produce sonita (ovum compounds (allylalchohol, allylthiol, and ovarian hormones) and nourishes the allylpropyl disulphide), prostaglandins breast.21 19 A2,D2,F2, and E2 . Mn 23.5%, Vit B6 17.5, In caraka samhita, the drug has Vit C 14.7, tryptohan 6.2%, selenium been indicated in skin diseases (kustha, 7.5%, Ca 5.1%. P 4.5%, Vit b 14%, Cu kilasa), vataja disorder (neurological 4%, protein 3.6%. disorder), and it increases the sperm count PROPERTIES: As the name lasona itself and sperm motility (vrsya)22. Vagbhata suggests the drug contains five rasas considered lasuna as the best among the except the amla rasa. Owing to different vatahara dravyas. He emphasized the role types of rasa present the drug has wide of lashoona as a rasayana in the treatment range of activities. Based on its action the of vat avaranas.23 drug has other synonyms like, arishta (able Contraindications :According to to cure many diseases), mahoushada (treat Kashyapa use of drug is contraindicated in vataja disorders), vatari (subsides vata), person with kapha and pitta origin, bhootaghna (microbicide), ugragandha progressive emaciation of the body, aged (having strong odor), deeragatraka and person, no digestive power, puerperal shulka kanda indicating the morphology of women, pregnant women, child suffering the plant. from ama, fever, diarrhea, who received

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[Usha Patil etal: Rasona (Allium sativum) A Wonder Drug from Ancient to Modern and Kitchen to Medicine] emesis, purgation, nasya, basti, suffering 7. Gulma – lashoona processed with milk from thirst, vomiting, cough, dyspnea, indicated in vatarakta, fever, cardiac ascites, lack of patience, helpless, poor and disorder, abscesses and oedema36. bad natured24. However, according to Pharmacological activities of Vagbhataacharya lashoona is Lashoona:Modern research has reported contraindicated during anemia, diseases of different therapeutic activities of the abdomen, chest injury, sopha, thirst, eye lashoona as Antimicrobial, 37 Anti diseases, emaciation, pittaj and raktaja oxidant38 Cardio protective39 Anti disorders.25 diabetic40 Cancer chemo preventive41 Dose /duration /time /season: Ideal dose Neuroprotective42 Nephroprotective43 in the kala (cold season) it is 4 pala or Immunomodulator44 and Anti ageing45. 50 number while in hemanta it is 6 pala or Study conducted on administering the 60 numbers and in sisira it is 8-19 pala or garlic in different farm, it was found that at 100 numbers. The duration of the approximate dose of 4 g/day for six treatment recommended is a minimum of months it has significantly reduced the 15 days and maximum of 6 months.26 LDL levels and other plasma lipid Purification : Lashoona tuber after concentrations in adults in moderate removing its outer covering is bifurcated cholestremia. and the ligule in the middle is removed and Antiplatelet activity: it contains allicin it is kept in curd overnight to remove its thiosulfinates responsible for antiplateletic bad odor. The drug is then washed, dried agent contribution to the prevention of and pounded before use27 cardiovascular diseases. Classical uses of lashoona: It helps in improving he iron metabolism, 1. Vatavyadhi (neurological disorder) : the di allyl sulfide in garlic helps in Oil cooked in lashoona juice was increasing production of a protein called. reportedly cures vata28, the drug is best Ferroprotein, a protein that runs across the remedy for vataja disorder29 cell membrane and forms passage where additionally the drug is used as a that allows stored iron to leave the cells rasayana to cure all types of avarana and become available where it is needed except pitta and rakta30 Cardioprotective; red blood cells, take 2. Amavata (Rheumatoid arthritis): sulfur containing molecule in garlic called alcoholic preparation of lashoona polysulfide and use them to produce (rasona sura) is indicated in hydrogen sulfide. This hydrogen sulfide Rheumatoid condition31 inturn help blood vessels expand and keep 3. External application of paste of our blood pressure in check. lashoona kill the organisms32 Antithrombotic and anticancer effect: 4. Paste of lashoona promotes lactation33 Garlic contains 20 kinds of sulfide 5. Rasayana – paste of lashoona mixed compounds, these functionctions are with ghee and honey taken for a period different from one another. of one year provides health and Important preparations : lasunadi vati, logivity34 rasonapinda, hingutriguna taila, 6. Disorders of female genital tract the rasonasura, lasuna kalpa, rasona Rasayana, juice of lashoona should be taken in rasonastaka, rasona vataka, lasuna the morning35 ksirapaka, lasunadi ghrta.

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Adverse effect: Garlic is known for 5. Prof.P.V.Tewari ,Kashyapa Samhita causing bad breath (halitosis), as well as (2002), Edited by Prof.P.V.Tewari, causing sweat to have a pungent "garlicky" translation and commentary by smell, which is caused by allyl methyl P.V.Tewari,Chaukhambaha sulfide (AMS). AMS is a volatile liquid Viswabharati oriental publishers which is absorbed into the blood during ,Kalpasthana chapter - 2,P the metabolism of garlic-derived sulfur 326-327. compounds; from the blood it travels to the 6. Vaidyaratnam P.S.Varier (1995),Indian lungs (and from there to the mouth, Medicinal plants,a compendium of 500 causing bad breath; and skin, where it is species,Orient longman,Vol–1 P-81. exuded through skin pores. Washing the 7. Dr.J.L.Satry(2014),Illustrated Dravya skin with soap is only a partial and Guna Vigyan,Chaukambha Orientalia, imperfect solution to the smell. Studies Varanasi,Vol 2,P-531-535 have shown sipping milk at the same time 8. Dr.J.L.Satry(2014),Illustrated Dravya as consuming garlic can significantly Guna Vigyan,Chaukambha Orientalia, neutralize bad breath. Mixing garlic with Varanasi,Vol 2,P - 531- 535 milk in the mouth before swallowing 9. Prof.P.V.Tewari ,Kashyapa Samhita reduced the odor better than drinking milk (2002), Edited by Prof.P.V.Tewari, afterward. Plain water, mushrooms and translation and commentary by P.V. basil may also reduce the odor; the mix of Tewari, Chaukhambaha Viswabharati fat and water found in milk, however, was oriental publishers Varanasi, the most effective.46 Kalpasthana chapter - 2, REFERENCES: 10. Prof.Dr. PriyaVrat Sharma(1998), 1. Prof.Dr.P.V. Sharma(2001),Dravyauna Nighantu,Chaukhamabha Vigyan vol–2,Chaukhambha Bharathi Orientalia P - 132 Academy,Varanasi, P.72 11. Prof.Priyavrat Sharma (1979), Kaideva 2. K.C.Chunekar,edited by Nighantu,Chaukambha Orientalia Dr.G.S.Pandey(1995),Bhavaprakasha Varanasi, Oshadhi VargaP-225 Nighantu,Chaukambha Bharati 12. Prof.Dr. Priyavrat Sharma(1998), Academy, Varanasi,P -132 Dhanvantari Nighantu,Chaukhamabha 3. Prof.P.V.Tewari ,Kashyapa Samhita Orientalia, Karaveeradi P–132. (2002), Edited by Prof.P.V.Tewari, 13. Vishwanath Dwivide,Raja nighantu, translation and commentary by P.V. ,Krishnadas Academy,Varanasi,P -197 Tewari, Chaukhambaha Viswabharati 14. Prof.Priyavrat Sharma(1979), Kaideva oriental publishers Varanasi, Nighantu, Chaukambha Orientalia Kalpasthana chapter - 2,P - 326-342 Varanasi, Oshadhi vargaP-225 4. Kashinath shastri, Caraka samhita, 15. Prof.Priyavrat Sharma,Shodala Edited by Dr.Gangasahaya Nighantu, Oriental Institute, Oshadhi Pandeya,Chaukambha Sanskrit varga P - 55 Sansthan, Part - 1 Sutrasthana 27th 16. K.C.Chunekar,edited by chapter, Prof. Priya Vrat Dr.G.S.Pandey(1995),Bhavaprakasha Sharma,Susruta Samhita, Chaukambha Nighantu,Chaukambha Bharati Viswabharati Varanasi,Sutrasthana Academy,Varanasi,132 Chaper 46

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17. Dr.K.M.Nadakarni’s,Indian Material chikistasthana,Krishnadas Academy, Medica part–2P-65 Varanasi, Sl - 24/348 18. Dr.J.L.Satry(2014),Illustrated Dravya 28. Kashinaha Shastri, Caraka samhita, Guna Vigyan,Chaukambha Orientalia, Edited by Ganga sahaya Pandey, Varanasi,Vol 2,P - 531- 535 Choukambha Sanskri sanathan, 19. Dr.J.L.Satry(2014) ,Illustrated Dravya Chikista sthana chapter 28 Guna Vigyan,Chaukambha Orientalia, 29. Prof. K.R.Srikantha Murthy Astanga Varanasi,Vol 2, P - 531 - 535 hradaya,Krishnadas Academy 20. K.C.Chunekar,edited by Varanasi, Uttara 40/52 Dr.G.S.Pandey(1995), Bhavaprakasha 30. Prof. K.R.Srikantha Murthy Astanaga nighantu,Chaukambha Bharati hradaya, Krishnadas Academy, Academy,Varanasi,132 Chikitsa sthana 22/70 21. Prof.P.V.Tewari ,Kashyapa Samhita 31. Priyavrat (2002), Edited by Prof.P.V.Tewari, Sharma(2002),Chakradatta,Chaukham translation and commentary by ba Publisher,Varanasi,Chapter 25./71- P.V.Tewari, Chaukhambaha 73 Viswabharati oriental publishers 32. Vrunda madhava 44/46 Varanasi, Kalpasthana chapter - 2,P - 33. Prof.P.V.Tewari ,Kashyapa Samhita 327 (2002), Edited by Prof.P.V.Tewari, 22. Kashinath shastri, Caraka samhita, translation and commentary by P.V. Edited by Dr.Gangasahaya Tewari, Chaukhambaha Viswabharati Pandeya,Chaukambha Sanskrit oriental publishers Varanasi, Sansthan, Part - 1 Sutrasthana 27th Kalpasthana chapter - 2, chapter 34. Prof.K.R.Srikantha Murthy,Astanga 23. Prof. K.R.Srikantha Murthy, Astanga sangraha of Vagbhata Uttara tantra, sangraha of Vagbhata Uttara 49/101 ,Kashyapa samhita page – 179 tantra,Chapter 49/100,118 – 121s 35. Prof. Priyavrat Sharma, Susruta 24. Prof.P.V.Tewari ,Kashyapa Samhita Samhita, Chaukambha Viswabharati (2002), Edited by Prof.P.V.Tewari, Varanasi, Uttaratantra 389-28 translation and commentary by P.V. 36. Kashinatha Shastri, Caraka samhita, Tewari, Chaukhambaha Viswabharati Edited by Ganga sahaya Pandey, oriental publishers Varanasi, Choukambha Sanskri sanathan, Kalpasthana chapter - 2, P - 329 Chikista sthana, Chapter 5/94-95 25. Prof. K.R.Srikantha Murthy,Astanga 37. Sivam GP. Protection sangraha of Vagbhata, Krishnadas against Helicobacter pylori and other Academy, Uttara tantra 49/131 bacterial infections by garlic. J Nutr 26. Prof.P.V.Tewari ,Kashyapa Samhita 2001;131:1106S-8S. (2002), Edited by Prof.P.V.Tewari, 38. Borek C. Antioxidant health effects of translation and commentary by P.V. aged garlic extract. J Nutr Tewari, Chaukhambaha Viswabharati 2001;131:1010S-5S oriental publishers Varanasi, 39. Asdaq SM, Inamdar MN. The potential Kalpasthana chapter - 2, P - 329 benefits of a garlic and 27. Prof. K.R. Srikanth Murhy, hydrochlorothiazide combination as Bhavaprakasaha

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antihypertensive and cardioprotective rats.Am J Physiol Renal in rats.J Nat Med 2011;65:81-8. Physiol2007;293:1691-8. 40. Ahmad MS, Ahmed N. Antiglycation 44. Kyo E, Uda N, Kasuga S, Itakura Y. properties of aged garlic extract: Immunomodulatory effects of aged Possible role in prevention of diabetic garlic extract. J Nutr 2001;131:1075S- complications. J Nutr 2006;136:796S- 9S 799S 45. Rahman K. Garlic and aging: New 41. Sengupta A, Ghosh S, Bhattacharjee S. insights into an old remedy. Ageing Allium vegetables in cancer Res Rev 2003;2:39-56. prevention: An overview. Asian Pac J 46. "Drinking a glass of milk can stop Cancer Prev 2004;5:237-45 garlic breath". BBC News. August 31, 42. Borek C. Garlic reduces dementia and 2010. Retrieved August 31, 2010. heart-disease risk. J Nutr 2006;136):810S-12S. CorrespondingAuthor: Dr.Usha Patil 43. Cruz C,Correa-Rotter R,Sánchez- Assistant Professor,Sri. Jayendra González DJ,Hernández-Pando Saraswathi Ayurveda College and R,Maldonado PD, Martínez- Hospital, Nazarathpet, Chennai MartínezCM, etal.Renoprotective and antihypertensive effects of S- Source of support: Nil allylcysteine in 5/6nephrectomized Conflict of interest: None Declared

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