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CHAPTER 29 ORGANIC CHEMICALS VI 29-1 Notes 1
)&f1y3X CHAPTER 29 ORGANIC CHEMICALS VI 29-1 Notes 1. Except where the context otherwise requires, the headings of this chapter apply only to: (a) Separate chemically defined organic compounds, whether or not containing impurities; (b) Mixtures of two or more isomers of the same organic compound (whether or not containing impurities), except mixtures of acyclic hydrocarbon isomers (other than stereoisomers), whether or not saturated (chapter 27); (c) The products of headings 2936 to 2939 or the sugar ethers and sugar esters, and their salts, of heading 2940, or the products of heading 2941, whether or not chemically defined; (d) Products mentioned in (a), (b) or (c) above dissolved in water; (e) Products mentioned in (a), (b) or (c) above dissolved in other solvents provided that the solution constitutes a normal and necessary method of putting up these products adopted solely for reasons of safety or for transport and that the solvent does not render the product particularly suitable for specific use rather than for general use; (f) The products mentioned in (a), (b), (c), (d) or (e) above with an added stabilizer (including an anticaking agent) necessary for their preservation or transport; (g) The products mentioned in (a), (b), (c), (d), (e) or (f) above with an added antidusting agent or a coloring or odoriferous substance added to facilitate their identification or for safety reasons, provided that the additions do not render the product particularly suitable for specific use rather than for general use; (h) The following products, diluted to standard strengths, for the production of azo dyes: diazonium salts, couplers used for these salts and diazotizable amines and their salts. -
United States Patent (19) (11 Patent Number: 4859,592 Hagedorn Et Al
United States Patent (19) (11 Patent Number: 4859,592 Hagedorn et al. 45 Date of Patent: Aug. 22, 1989 54 PRODUCTION OF PICOL.INIC ACID AND OTHER PUBLICATIONS PYRIDINE PRODUCTS VIA PSEUDOMONAS Dagley, et al., "New Pathways in the Oxidative Metab olism of Aromatic Compounds by Micro-Organisms'; (76 Inventors: Scott R. Hagedorn, Old Coach Rd., Summit, N.J. 07087; Anthony J. East, Nature, V. 188, pp. 560-566 (1960). 63 Niles Ave., Madison, N.J. O7940; Moser et al., “Decarboxylation of 5-Sub Sol J. Barer, 271 White Oak Ridge stituted-2-Pyridinecarboxylic Acids', J. Org. Chem., Rd., Bridgewater, N.J. 08807 V. 37, No. 24, pp. 3938-3940 (1972). Primary Examiner-Elizabeth C. Weimar 21) Appl. No.: 759,038 Attorney, Agent, or Firm-Mathews, Woodbridge, 22 Filed: Jul. 26, 1985 Goebel, Pugh & Collins (51) Int. Cl." ........................ C12P 17/12; C12N 1/20; (57) ABSTRACT C12R 1/40 (52) U.S. Cl. ................................. 435/122; 435/253.3; This invention provides a process for the bioconversion 435/877 of a non-growth aromatic feed to an accumulated quan tity of a picolinic acid product with reduced accumula (58) Field of Search ............. 435/122, 253, 877, 253.3 tion of 2-hydroxymuconic semialdehyde, and con 56 References Cited ducted in the presence of ammonium or a primary U.S. PATENT DOCUMENTS amine, which acid subsequently can be converted by 4,654,303 3/1987 Hagedorn ......................... 435/1723 chemical means to a pyridine product. 4,666,841 5/1987 Hagedorn ... ... 435/122 4,673,646 6/1987 Hagedorn ............ was sex as a was u + 435/146 6 Claims, 2 Drawing Sheets U.S. -
Method for Preparing 2,3-Dichloro-1-Propanol and 3-Chloro-1-Propanol
Europaisches Patentamt 19 European Patent Office Office europeen des brevets © Publication number : 0 579 362 A1 EUROPEAN PATENT APPLICATION © Application number : 93303893.7 © int. ci.5: C07C 31/36, C07C 29/32 @ Date of filing : 19.05.93 © Priority: 13.07.92 JP 184910/92 @ Inventor: Watanabe, Hiroyoshi 18.12.92 JP 338584/92 3-4-1-141, Toriishi Takaishi-shi, Osaka-fu (JP) Inventor : Hayakawa, Fumie @) Date of publication of application : 4-7-3-342, Kamo 19.01.94 Bulletin 94/03 Takaishi-shi, Osaka-fu (JP) © Designated Contracting States : © Representative : Stuart, Ian Alexander et al DE FR GB IT NL MEWBURN ELLIS 2 Cursitor Street London EC4A 1BQ (GB) © Applicant : MITSUI TOATSU CHEMICALS, Inc. 2-5 Kasumigaseki 3-chome Chiyoda-Ku Tokyo 100 (JP) © Method for preparing 2,3-dichloro-1-propanol and 3-chloro-1-propanol. © A method for preparing 2,3-dichloro-l- propanol and 23-chloro-l-propanol is here dis- closed which comprises the step of reacting 1,2-dichloroethane with methanol by irradiation with light in the presence of at least one com- pound selected from europium compounds, samarium compounds and ytterbium com- pounds, and if necessary, in the additional pre- sence of a zeolite. CM CO CO o> ro- ta LU Jouve, 18, rue Saint-Denis, 75001 PARIS 1 EP 0 579 362 A1 2 The present invention relates to a method for pre- As a method to solve these problems, the pres- paring 2,3-dichloro-1-propanol and 3-chloro-1- ent inventor have suggested a method for preparing propanol. -
Synthesis of New Thiazole and Thiazolyl Derivatives of Medicinal Significant-A Short Review
MOJ Bioorganic & Organic Chemistry Mini Review Open Access Synthesis of new thiazole and thiazolyl derivatives of medicinal significant-a short review Abstract Volume 2 Issue 2 - 2018 In the field of therapeutic science, thiazoles are of extraordinary importance, because of their potent and significant biological activities. Likewise thiazole and their Weiam Hussein,1 Gülhan Turan- derivatives are found in various powerful naturally and biologically active compounds Zitouni2 which possess a broad spectrum of biological activity therefore, synthesis of this 1Department of Pharmaceutical Chemistry, Aden University, compound is of remarkable concern. This review primarily focuses on the updated Yemen research papers reported in literature for the synthesis of thiazole and thiazolyl 2Department of Pharmaceutical Chemistry, Anadolu University, compounds. Turkey Keywords: thiazoles, thiazolyl, synthetic procedures, biological activity Correspondence: Weiam Hussein, Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey, Tel +905074929053, Email [email protected] Received: February 23, 2018| Published: March 12, 2018 Introduction Kaplancikli et al. 11 reported a simple and three steps-reaction procedure for the synthesis of new benzimidazole-thiazole derivatives. The synthesis of heterocyclic rings has been a fascinating field 4-(1H-benzimidazol-1-yl)benzaldehyde was prepared by reacting in therapeutic science. Various heterocyclic compounds containing 1H-benzimidazole and 4-fluorobenzaldehyde under microwave nitrogen and sulfur have flexible frameworks for drugs development irradiation, then, the reaction between 4-(1H-benzimidazol- and design.1 Thiazole is one of the most intensively studied classes of 1-yl)benzaldehyde and hydrazine carbothioamide gave as a aromatic five-membered heterocyclics. It was first defined by Hantzschresult 2-(4-(1H-benzimidazol-1-yl)benzylidene)hydrazine-1- and Weber in 1887. -
Dupont™ Tychem® 5000
DuPont™ Tychem® 5000 C3525T TN DuPont™ Tychem® 5000 DuPont™ Tychem® 5000 Encapsulated Level B Suit. Flat Back, Front Entry. Standard Visor, 1 Layer: 20 mil PVC. Elastic Wrists. Double Storm Flap with Hook & Loop Closure. Airline Access. One Exhaust Vent. Taped Seams. Tan. Name Description Full Part Number C3525TTNxx0006yy (xx=size;yy=option code) Fabric/Materials Tychem® 5000 Design Encap. Level B, Flat Back, Front Entry Seam Taped Color Tan Quantity/Box 6 per case Sizes SM, MD, LG, XL, 2X, 3X, 4X Option Codes 00 September 23, 2021 DuPont™ Tychem® 5000 Page 1 of 21 FEATURES & PRODUCT DETAILS Tychem® 5000 fabric is composed of a multi-layer film barrier laminated to a durable 2.0 oz/yd2 polypropylene substrate. Tychem® 5000 fabric is strong and durable for rigorous activities and rugged situations involving liquid splash and provides barrier to a broad range of chemicals. Typical Applications: chemical handling, petro-chemical, hazardous materials/waste clean-up, fire departments, industrial hazmat teams, utilities, and domestic preparedness. Commonly used in domestic preparedness for situations where the potential to exposure to chemicals exist. September 23, 2021 DuPont™ Tychem® 5000 Page 2 of 21 Encapsulated design provides protection from liquid splash exposure for both the wearer and respiratory equipment Also provides coverage from overhead liquid splash (does not provide vapor protection) Taped seams provide strong chemical resistance against heavy liquid splashes. A sewn seam is covered with a strip of compatible chemical-resistant -
Ethylene Glycol
Ethylene glycol Ethylene glycol (IUPAC name: ethane-1,2-diol) is an organic Ethylene glycol compound with the formula (CH2OH)2. It is mainly used for two purposes, as a raw material in the manufacture of polyester fibers and for antifreeze formulations. It is an odorless, colorless, sweet-tasting, viscous liquid. Contents Production Industrial routes Biological routes Historical routes Uses Coolant and heat-transfer agent Antifreeze Precursor to polymers Other uses Dehydrating agent Hydrate inhibition Applications Chemical reactions Toxicity Environmental effects Names Notes Preferred IUPAC name References Ethane-1,2-diol External links Other names Ethylene glycol 1,2-Ethanediol Production Ethylene alcohol Hypodicarbonous acid Monoethylene glycol Industrial routes 1,2-Dihydroxyethane Ethylene glycol is produced from ethylene (ethene), via the Identifiers intermediate ethylene oxide. Ethylene oxide reacts with water to CAS Number 107-21-1 (http produce ethylene glycol according to the chemical equation: s://commonche mistry.cas.org/d C2H4O + H2O → HO−CH2CH2−OH etail?cas_rn=10 7-21-1) 3D model (JSmol) Interactive This reaction can be catalyzed by either acids or bases, or can occur image (https://ch at neutral pH under elevated temperatures. The highest yields of emapps.stolaf.e ethylene glycol occur at acidic or neutral pH with a large excess of du/jmol/jmol.ph water. Under these conditions, ethylene glycol yields of 90% can be p?model=OCC achieved. The major byproducts are the oligomers diethylene glycol, O) triethylene glycol, and tetraethylene glycol. The separation of these oligomers and water is energy-intensive. About 6.7 million tonnes 3DMet B00278 (http://w are produced annually.[4] ww.3dmet.dna.af frc.go.jp/cgi/sho A higher selectivity is achieved by use of Shell's OMEGA process. -
Potassium Thiocyanate 1
MSDS Number: P6181 * * * * * Effective Date: 03/10/11 * * * * * Supersedes: 11/21/08 POTASSIUM THIOCYANATE 1. Product Identification Synonyms: Potassium sulfocyanate; Potassium thiocyanide; Thiocyanic acid, potassium salt; Potassium isothiocyanate CAS No.: 333-20-0 Molecular Weight: 97.18 Chemical Formula: KSCN Product Codes: J.T. Baker: 3326, 5578 Macron: 7168 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Potassium Thiocyanate 333-20-0 90 - 100% Yes 3. Hazards Identification Emergency Overview -------------------------- WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. SAF-T-DATA(tm) Ratings (Provided here for your convenience) ----------------------------------------------------------------------------------------------------------- Health Rating: 2 - Moderate (Life) Flammability Rating: 0 - None Reactivity Rating: 1 - Slight Contact Rating: 2 - Moderate Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES Storage Color Code: Green (General Storage) ----------------------------------------------------------------------------------------------------------- Potential Health Effects ---------------------------------- Inhalation: Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath. Ingestion: May cause psychosis, vomiting, disorientation, weakness, low blood pressure, convulsions and death which may be delayed. The probable lethal -
LIST of ANNEXURES SR. NO. NAME of ANNEXURE I List of Products
LIST OF ANNEXURES SR. NO. NAME OF ANNEXURE I List of Products and Raw materials along with their Production Capacity II Layout Map of the Plant III Brief Manufacturing Process Description IV Details of water consumption & waste water generation V Details of Effluent Treatment Scheme VI Details of Hazardous Waste Generation and Disposal VII Details of Stacks and Vents, Fuel & Energy Requirements VIII Details of Hazardous Chemicals Storage & Handling IX Socio-economic Impacts X Proposed Terms of Reference XI GIDC Plot Allotment Letter XII ETL Membership Letter (M/s. ETL) XIII TSDF & CHWIF Membership Letter (M/s BEIL) XIV Toposheet XV Copy of existing CCA ANNEXURE-I _____________________________________________ _________________________ LIST OF PRODUCTS ALONG WITH THEIR PRODUCTION CAPACITY WITH RAW MATERIALS PRODUCTION CAPACITY (MT/MONTH) SR. PRODUCTS CAS NO NO EXISTING ADDITIONAL TOTAL QUANTITY QUANTITY PROPOSED QUANTITY EXISITING PRODUCTS 1 Optical Brightening Agent 13001-39-3 1.0 0 1.0 2 Ortho Toluene Nitrite 88-72-2 4.0 0 4.0 TOTAL (EXISITING PRODUCTS) 5.0 0 5.0 PROPOSED PRODUCTS 1 Darunavir 206361-99-1 5 5 2 Levosulpiride 23672-07-3 10 10 3 Montelukast Sodium 151767-02-1 5.5 5.5 4 Tramadol hydrochloride 36282-47-0 7 7 5 Nifedipine 21829-25-4 4.5 4.5 6 Quetiapinehemifumarate 111974-72-2 3 3 7 Furosemide 54-31-9 3.5 3.5 8 Risedronate Sodium 105462-24-6 4.5 4.5 66108-95- 0/60166-93- 9 Iohexol/Iopamidol/Iodixanol 0/92339-11- 2 6 6 10 Lauryl Pyridinium chloride 104-74-5 10 10 11 Vildagliptin 274901-16-5 4 4 12 Ambroxol Hydrochloride 23828-92-4 -
1 Abietic Acid R Abrasive Silica for Polishing DR Acenaphthene M (LC
1 abietic acid R abrasive silica for polishing DR acenaphthene M (LC) acenaphthene quinone R acenaphthylene R acetal (see 1,1-diethoxyethane) acetaldehyde M (FC) acetaldehyde-d (CH3CDO) R acetaldehyde dimethyl acetal CH acetaldoxime R acetamide M (LC) acetamidinium chloride R acetamidoacrylic acid 2- NB acetamidobenzaldehyde p- R acetamidobenzenesulfonyl chloride 4- R acetamidodeoxythioglucopyranose triacetate 2- -2- -1- -β-D- 3,4,6- AB acetamidomethylthiazole 2- -4- PB acetanilide M (LC) acetazolamide R acetdimethylamide see dimethylacetamide, N,N- acethydrazide R acetic acid M (solv) acetic anhydride M (FC) acetmethylamide see methylacetamide, N- acetoacetamide R acetoacetanilide R acetoacetic acid, lithium salt R acetobromoglucose -α-D- NB acetohydroxamic acid R acetoin R acetol (hydroxyacetone) R acetonaphthalide (α)R acetone M (solv) acetone ,A.R. M (solv) acetone-d6 RM acetone cyanohydrin R acetonedicarboxylic acid ,dimethyl ester R acetonedicarboxylic acid -1,3- R acetone dimethyl acetal see dimethoxypropane 2,2- acetonitrile M (solv) acetonitrile-d3 RM acetonylacetone see hexanedione 2,5- acetonylbenzylhydroxycoumarin (3-(α- -4- R acetophenone M (LC) acetophenone oxime R acetophenone trimethylsilyl enol ether see phenyltrimethylsilyl... acetoxyacetone (oxopropyl acetate 2-) R acetoxybenzoic acid 4- DS acetoxynaphthoic acid 6- -2- R 2 acetylacetaldehyde dimethylacetal R acetylacetone (pentanedione -2,4-) M (C) acetylbenzonitrile p- R acetylbiphenyl 4- see phenylacetophenone, p- acetyl bromide M (FC) acetylbromothiophene 2- -5- -
Background Material:1997-11-12 Diethyl Sulfate As a Federal
DIETHYL SULFATE Diethyl sulfate is a federal hazardous air pollutant and was identified as a toxic air contaminant in April 1993 under AB 2728. CAS Registry Number: 64-67-5 (C2H5)2SO4 Molecular Formula: C4H10O4S Diethyl sulfate is a colorless, moderately viscous, oily liquid with a peppermint odor. It is miscible with alcohol and ether. Diethyl sulfate decomposes into ethyl hydrogen sulfate and alcohol upon heating or in hot water (NTP, 1991). Physical Properties of Diethyl Sulfate Synonyms: sulfuric acid diethyl ester; ethyl sulfate; diethyl sulphate Molecular Weight: 154.19 Boiling Point: 209.5 oC Melting Point: -25 oC Flash Point: 104 oC Vapor Density: 5.31 (air = 1) Density/Specific Gravity: 1.1774 at 20/4 oC (water = 1) Vapor Pressure: 1 mm Hg at 47 oC Conversion Factor: 1 ppm = 6.31 mg/m3 (HSDB, 1991; Merck, 1983; U.S. EPA, 1994a) SOURCES AND EMISSIONS A. Sources Diethyl sulfate is used as an alkylating agent, and to convert hydrogen compounds such as phenols, amines, and thiols to their corresponding ethyl derivatives. Diethyl sulfate can also be used in the preparation of intermediates and products in surfactants, dyes, agricultural chemicals, pharmaceuticals, and other specialty products (NTP, 1991). It has also been detected as a contaminant in thiophosphate insecticides (HSDB, 1991). B. Emissions No emissions of diethyl sulfate from stationary sources in California were reported, based on data obtained from the Air Toxics “Hot Spots” Program (AB 2588) (ARB, 1997b). Toxic Air Contaminant Identification List Summaries - ARB/SSD/SES September 1997 389 Diethyl Sulfate C. Natural Occurrence No information about the natural occurrence of diethyl sulfate was found in the readily- available literature. -
Alphabetical Index of Substances and Articles
ALPHABETICAL INDEX OF SUBSTANCES AND ARTICLES - 355 - NOTES TO THE INDEX 1. This index is an alphabetical list of the substances and articles which are listed in numerical order in the Dangerous Goods List in Chapter 3.2. 2. For the purpose of determining the alphabetical order the following information has been ignored even when it forms part of the proper shipping name: numbers; Greek letters; the abbreviations “sec” and “tert”; and the letters “N” (nitrogen), “n” (normal), “o” (ortho) “m” (meta), “p” (para) and “N.O.S.” (not otherwise specified). 3. The name of a substance or article in block capital letters indicates a proper shipping name. 4. The name of a substance or article in block capital letters followed by the word “see” indicates an alternative proper shipping name or part of a proper shipping name (except for PCBs). 5. An entry in lower case letters followed by the word “see” indicates that the entry is not a proper shipping name; it is a synonym. 6. Where an entry is partly in block capital letters and partly in lower case letters, the latter part is considered not to be part of the proper shipping name. 7. A proper shipping name may be used in the singular or plural, as appropriate, for the purposes of documentation and package marking. - 356 - INDEX Name and description Class UN No. Name and description Class UN No. Accumulators, electric, see 4.3 3292 Acid mixture, nitrating acid, see 8 1796 8 2794 8 2795 Acid mixture, spent, nitrating acid, see 8 1826 8 2800 8 3028 Acraldehyde, inhibited, see 6.1 1092 ACETAL 3 1088 -
Safety Data Sheet Material Name: HFCL4 SDS ID: 00227583P
Safety Data Sheet Material Name: HFCL4 SDS ID: 00227583P Section 1 - PRODUCT AND COMPANY IDENTIFICATION Material Name HFCL4 Synonyms HAFNIUM TETRACHLORIDE; HAFNIUM (IV) CHLORIDE; (T-4) HAFNIUM CHLORIDE (HfCl4); HAFNIUM CHLORIDE; Cl4Hf Chemical Family metal, halides Product Use semiconductor manufacture Restrictions on Use None known Details of the supplier of the safety data sheet Entegris, Inc. 129 Concord Road Building 2 Billerica, MA 01821 USA Telephone Number: +1-952-556-4181 Telephone Number: +1-800-394-4083 (toll free within North America) Emergency Telephone Number: CHEMTREC - U.S. - 1-800-424-9300 CHEMTREC - Intl. - 1-703-527-3887 E-mail: [email protected] Section 2 - HAZARDS IDENTIFICATION Classification in accordance with paragraph (d) of 29 CFR 1910.1200. Combustible Dust Skin Corrosion/Irritation - Category 1B Serious Eye Damage/Eye Irritation - Category 1 Specific target organ toxicity - Single exposure - Category 3 ( respiratory system ) GHS Label Elements Symbol(s) Signal Word Danger Hazard Statement(s) ____________________________________________________________ Page 1 of 9 Issue date: 2021-05-11 Revision 6.0 Print date: 2021-05-12 Safety Data Sheet Material Name: HFCL4 SDS ID: 00227583P May form combustible dust concentrations in air. Causes severe skin burns and eye damage. May cause respiratory irritation. Precautionary Statement(s) Prevention Do not breathe dust. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Use only outdoors or in a well-ventilated area. Response Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Specific treatment may be needed, see first aid section of Safety Data Sheet.