RESEARCH ARTICLE Intestinal FXYD12 and sodium-potassium ATPase: A comparative study on two euryhaline medakas in response to salinity changes Wen-Kai Yang1,2,3, An-Di Hsu1, Chao-Kai Kang4, Ivan Pochou Lai5¤, Pei-Shao Liao5¤, Tsung-Han Lee1,2* a1111111111 1 Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan, 2 The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan, 3 Bachelor Degree Program in a1111111111 Animal Healthcare, Hungkuang University, Taichung, Taiwan, 4 Tainan Hydraulics Laboratory, National a1111111111 Cheng Kung University, Tainan, Taiwan, 5 National Taichung First Senior High School, Taichung, Taiwan a1111111111 a1111111111 ¤ Current address: School of Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan *
[email protected] Abstract OPEN ACCESS + + Citation: Yang W-K, Hsu A-D, Kang C-K, Lai IP, FXYD proteins are the regulators of sodium-potassium ATPase (Na /K -ATPase, NKA). In Liao P-S, Lee T-H (2018) Intestinal FXYD12 and teleosts, NKA is a primary driving force for the operation of many ion transport systems in sodium-potassium ATPase: A comparative study the osmoregulatory organs (e.g. intestines). Hence, the purpose of this study was to deter- on two euryhaline medakas in response to salinity mine the expression of FXYD proteins and NKA -subunit in the intestines of two closely changes. PLoS ONE 13(7): e0201252. https://doi. α org/10.1371/journal.pone.0201252 related medakas (Oryzias dancena and O. latipes), which came from different salinity habi- tats and have diverse osmoregulatory capabilities, to illustrate the association between NKA Editor: Patrick Prunet, Institut National de la Recherche Agronomique, FRANCE and FXYD proteins of two medaka species in response to salinity changes.