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Metal-On-Metal Hip Arthroplasty
METAL-ON-METAL HIP ARTHROPLASTY: INDICATIONS FOR CONTINUED USE IN LIGHT OF ADVERSE REACTION TO METAL DEBRIS by GULRAJ SINGH MATHARU A thesis submitted to the University of Birmingham for the degree of MASTERS OF RESEARCH IN CLINICAL RESEARCH School of Health and Population Sciences College of Medical and Dental Sciences University of Birmingham October 2014 University of Birmingham Research Archive e-theses repository This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder. ABSTRACT Adverse reaction to metal debris (ARMD) represents a recently recognised mode of failure of metal-on-metal (MoM) hip resurfacings (HRs) and total hip replacements (THRs). ARMD often requires revision surgery which can have poor outcomes, therefore questioning the future role of MoM hip bearings. The 14-year survival of 447 HRs implanted by a designing surgeon was 94.1% (95% CI 84.9%-97.3%) with the best outcomes in males with primary osteoarthritis. The 8-year survival of 578 MoM THRs was 88.9% (95% CI 78.5%-93.4%) with 44% (17 of 39) of revisions performed for ARMD. A systematic review identified six studies reporting short-term outcomes following 216 ARMD revisions with variable complication (4%-68%) and re-revision (3%-38%) rates. -
Continuous Improvement Project: Filter Manufacturing Department at BAT in Heidelberg
BPJ 410 – Final Report Continuous Improvement Project: Filter Manufacturing Department at BAT in Heidelberg Benito Decina s28345186 Executive Summary Production industries are subject to the ebb and flow of demand and supply fluctuations, with an increase in a product’s demand driving up the supplier’s production. At BAT’s factory in Heidelberg, the Filter Manufacturing Department is currently operating at nothing more than 75% efficiency, and is the bottleneck in BAT’s production process. If BAT plans to keep up with the increase in consumer demand, improvement is needed. To achieve a more acceptable production efficiency of about 85 to 95%, blockages hindering filter supply need to be minimised, changeover times reduced, and waste production needs to be kept to a minimal. The only way to achieve this objective would be to analyse the current layout, identify its flaws and areas of improvement, and then implement a new layout that would improve the department’s performance and complement future objectives. With the aid of simulation models, information is retrieved to determine the extent of improvements the proposed layout will be able to provide. The freed up floor space created by the proposed layout design will also be looked at to determine its best possible use. The information gathered from the simulations as well as the available floor space will provide a clear indication of the viability of the proposed layout. i Table of Contents 1. Introduction and Background ........................................................................................................ -
Senate the Senate Met at 9:30 A.M
E PL UR UM IB N U U S Congressional Record United States th of America PROCEEDINGS AND DEBATES OF THE 109 CONGRESS, SECOND SESSION Vol. 152 WASHINGTON, THURSDAY, DECEMBER 7, 2006 No. 134 Senate The Senate met at 9:30 a.m. and was Eternal Lord God, our stronghold in Thank You for their investment in called to order by the President pro times of trouble, bless today our Sen- freedom and their sacrifices for our lib- tempore (Mr. STEVENS). ators. Lord, 65 years ago, America ex- erties. Comfort those who mourn and PRAYER perienced a day of infamy. As we re- those who bear the scars of battle. Be a member Pearl Harbor, our hearts turn companion to those who must stare at The Chaplain, Dr. Barry C. Black, of- fered the following prayer: toward the men and women of our an empty chair during this holiday sea- Let us pray. Armed Forces and their families. son. Defend those in harm’s way with N O T I C E The Government Printing Office will publish corrections to the Congressional Record as a pilot program that has been authorized by the U.S. Senate and House of Representatives. Corrections to the online Congressional Record will appear on the page on which the error occurred. The corrections will also be printed after the History of Bills and Resolutions sec- tion of the Congressional Record Index for print-only viewers of the Congressional Record. By order of the Joint Committee on Printing. TRENT LOTT, Chairman. N O T I C E If the 109th Congress, 2d Session, adjourns sine die on or before December 15, 2006, a final issue of the Congres- sional Record for the 109th Congress, 2d Session, will be published on Wednesday, December 27, 2006, in order to permit Members to revise and extend their remarks. -
Smoking and Quitting Behaviour in Lockdown South Africa
SMOKING AND QUITTING BEHAVIOUR IN LOCKDOWN SOUTH AFRICA: RESULTS FROM A SECOND SURVEY Professor Corné van Walbeek Samantha Filby Kirsten van der Zee 21 July 2020 1 EXECUTIVE SUMMARY This report is based on the results of an online survey, conducted between 4 June and 19 June 2020. The study was conducted by the Research Unit on the Economics of Excisable Products (REEP), an independent research unit based at the University of Cape Town. It was funded by the African Capacity Building Foundation, which in turn is funded by the Bill & Melinda Gates Foundation. This report follows on from our first report entitled “Lighting up the illicit cigarette market: Smokers’ responses to the cigarette sales ban in South Africa”, which was published on 15 May 2020. That report was based on an online survey conducted between 29 April and 11 May 2020. When the second survey was conducted, the ban on the sales of cigarettes had been extended, even as the country had moved from lockdown Level 4 to Level 3. The questionnaire was distributed on Twitter, Change.org (a petition site) and Moya (a data-free platform). The survey yielded 23 631 usable responses. In contrast to the first study, we did not weigh the data, because the sampling methodology (i.e. online survey) made it impossible to reach the poorer segments of society. We thus do not claim that the data is nationally representative; we report on the characteristics of the sample, not the South African smoking population. In the report we often report the findings by race and gender, because smoking behaviour in South Africa has very pronounced race-gender differences. -
Annual Report 2012.Pub
FFFROM THE FIRST REGENT OVER THE PAST EIGHT YEARS , the plantation of George Mason enjoyed meticulous restoration under the directorship of David Reese. Acclaim was univer- sal, as the mansion and outbuildings were studied, re- paired, and returned to their original stature. Contents In response to the voices of community, staff, docents From the First Regent 2 and the legislature, the Board of Regents decided in early 2012 to focus on programming and to broadened interac- 2012 Overview 3 tion with the public. The consulting firm of Bryan & Jordan was engaged to lead us through this change. The work of Program Highlights 4 the Search Committee for a new Director was delayed while the Regents and the Commonwealth settled logistics Education 6 of employment, but Acting Director Mark Whatford and In- terim Director Patrick Ladden ably led us and our visitors Docents 7 into a new array of activity while maintaining the program- ming already in place. Archaeology 8 At its annual meeting in October the Board of Regents adopted a new mission statement: Seeds of Independence 9 To utilize fully the physical and scholarly resources of Museum Shop 10 Gunston Hall to stimulate continuing public exploration of democratic ideals as first presented by Staff & GHHIS 11 George Mason in the 1776 Virginia Declaration of Rights. Budget 12 The Board also voted to undertake a strategic plan for the purpose of addressing the new mission. A Strategic Funders and Donors 13 Planning Committee, headed by former NSCDA President Hilary Gripekoven and comprised of membership repre- senting Regents, staff, volunteers, and the Commonwealth, promptly established goals and working groups. -
Controlling the Tobacco Barons in South Africa Why the Framework Convention Is Necessary
Controlling the Tobacco Barons in South Africa Why the Framework Convention is necessary By Peter Mann, Chief Executive, Meropa Communications World Health Organisation Change Agents for the “Don’t be Duped” campaign ------------------------------------------------------------------------------------------------------- Meropa Communications is the leading public relations consultancy in South Africa with some 50 staff and an equal number of blue-chip clients – ranging from the Merrill Lynch’s of the world to British Airways. I say this not to be boastful but to indicate the seriousness of the issue with which we are dealing and to illustrate our company’s commitment to this cause. We will no longer take tobacco money. It is with some embarrassment that I acknowledge that, at the behest of our then UK parent, we once did. It was an extraordinary experience. Because the UK company represented them around the world we were required to be part of the service and placed on a handsome retainer. Yet, they seldom asked us to do any work. Only once was I asked to arrange a meeting with an editor. I am pleased to say the level of hostility I encountered was such that the meeting never took place. Why will we no longer take tobacco money and why have we approached the WHO to become an active participant in the Don’t be Duped campaign? We sat as an agency and watched the tobacco barons trying to undermine the South African Government’s laudable anti-smoking regulations. We sat and watched what appeared to be deliberate campaigns aimed at various disadvantaged South African market segments – namely, blacks, women and youth. -
Student Handbook 2019-2020
STUDENT HANDBOOK 2019-2020 UNSTON IDDLE CHOOL G M S Home of the Horne ts 2700 S. Lang Street Arlington, Virginia 22206 http://www.apsva.us/gunston/ Dr. Lori A. Wiggins Principal Office Hours: 7:00 a.m. to 4:00 p.m. School Hours: 7:50 a.m. to 2:24 p.m. Main Office: (703) 228–6900 Student Handbook 2019-2020 1 Dear Gunston Students! This handbook is created for you, so that you will understand the important resources, rules and regulations, which help make Gunston Middle School a positive, rewarding, and safe place to learn. Middle school is a time of great growth; emotional, mental, and physical. It is important that you read this handbook; it will help guide you in making good decisions and taking responsibility for your own learning and for your behavior. Expectations at Gunston is based on developing positive relationships among students, teachers, parents, and administrators. We take PRIDE (Preparation, Respect, Integrity, Determination, and Excellence) in our academic journey. Gunston PRIDE is used to guide you as you learn to be more self-directed and self-disciplined. We are here to help you maintain these goals by encouraging you to be a positive member of our school community. Read this handbook carefully, and be sure you understand everything it says about student attendance, behavior and available school resources. If you have any questions about information in this handbook, be sure to ask your teachers, guidance counselors, administrators, or other staff members for support. Wishing you a GREAT school year, Lori Wiggins, Ed.D. -
What Is Hip Resurfacing?
What is Hip Resurfacing? When the cartilage covering the weight-bearing areas of the hip joint is lost in osteoarthritis, the resultant rubbing of bone on bone produces pain, stiffness and limp. Figure 1: Femoral Head and Neck Removed at Total Hip Replacement showing Area of Cartilage Loss Fig 1 shows this cartilage loss in a fairly small area of the head of the femur. It begs the question why Total Hip Replacement (THR), the accepted treatment for this condition, is so radical, involving as it does, removal of the femoral head and neck, insertion of a metal stem down the upper femur and insertion of a prosthetic cup into the socket as shown in Fig 2. Figure 2: Osteoarthritic Hip Pre and Post Op with Conventional Uncemented Total Hip Replacement Professor Sir John Charnley attempted treatment of the arthritic hip in the 1950’s with hip resurfacing, where only the cartilage of the femoral head and socket were replaced with thin layers of polytetrafluoroethylene (PTFE). These implants unfortunately failed within months, Charnley thinking that the culprit was death of the femoral head as a result of interrupting its blood supply. He therefore moved on to a THR using PTFE cups paired with metal stemmed femoral components. Initially these were successful, and he carried out some 300 procedures. The initial success was not maintained, and at 2 years the implants started to fail with osteolysis [bone loss associated with the debris caused by wear]. Most of these patients needed further revision surgery, very distressing for them and their surgeon alike. -
Politics, the Economy, the Arts, and the Inner Workings
to understand politics, the economy, the arts, and the inner workings ......................................... Every week the editors of THE NEW I REPUBLIC put together the best ideas and FREE ISSUE RESERVATION boldest commentary available on the political, Yes, please send me the next issue of THE NEW social, and cultural scene. REPUBLIC - absolutely free. If1 like it, I'll pay just $19.99 for a six month's subscription (23 more issues for a total of 24). That's a savings of 42% oft' the basic subscription price.'i' I SATISFACTION GUARANTEED: I If I choose not to subscribe I'll write "cancel" across your invoice. return it, and owe nothing at all. Either way the free issue is mine to keep. Name Lind focus in on the true stories behind the Address headlines. Writers like Stanley Crouch, Naomi City State Zip Wolf, John Updike, Malcolnl Gladwell, and Tatyana Tolstaya are regular contributors. :: Introductory offer valid fur first time .siihsrrihers Stanley Kauffmann and Robert Brustein cover only. Please caillforforeign rates. the latest in film and theater, and Mark Strand brings you the best in contemporary poetry. Discover the award-winning weekly, THE NEW REPUBLIC, where politics, art, culture, and opinion are presented with style, wit and intelligence. Return this coupon to: The New Republic P.O. Box 602 1220 19th Street, N.W. Mt. Morris, IL 61054 AWQ952 Washington, D.C. 20036 L--_---------------_----------_-----_---- : Less than the cost of a cup of cappuccino AUTUMN 1995 THE WILSON QUARTERLY Published by the Woodrow Wilson International Center for Scholars 6 AMERICA'SGAMBLING FEVER Jackson Lears Robert Goodman David Spanier Once ranked high among the vices, gambling has burgeoned into a $40 billion legal industry in the United States. -
1 Total Hip Replacement: Introduction, Sources and Outline
Notes 1 Total Hip Replacement: Introduction, Sources and Outline 1 ‘Railway Engineer’s Suicide’, The Times (9 May 1933). 2 Henderson, Melvin S. and Pollock, George A., ‘Surgical Treatment of Osteoarthritis of the Hip Joint’, Journal of Bone and Joint Surgery, 22 (1940), 923. 3 Cortisone was first synthesised in 1948 by the pharmaceutical company Merck. For the story of cortisone see Le Fanu, James, The Rise and Fall of Modern Medicine (London: Little, Brown and Company, 1999), 17–28. 4 Most of the early designs of these single component prostheses were devel- oped mainly in the US and in France. See Coventry, Mark B., ‘Lessons Learned in 30 Years of Total Hip Arthroplasty’, Clinical Orthopaedics and Related Research, 274 (1992), 22–9. 5 See Lerner, Barron H., The Breast Cancer Wars: Hope, fear and the pursuit of a cure in twentieth-century America (Oxford: Oxford University Press, 2001). For reflections on the role of surgery in different countries see Pickstone, John V., ‘Contested Cumulations: Configurations of cancer treatments through the twentieth century’, Bulletin of the History of Medicine, 81 (2007), 164–96. 6 For a history of TB in the twentieth century see Bryder, Linda, Below the Magic Mountain: A social history of tuberculosis in twentieth century Britain (Oxford: Oxford University Press, 1988). 7 Osteoarthritis is a degenerative condition, usually seen in older people and often affecting weight bearing joints in the lower limbs. See Cantor, David, ‘Representing “The Public”: Medicine, charity and emotion in twentieth century Britain’, in Sturdy, Steve (ed.), Medicine, Health and the Public Sphere in Britain, 1600–2000 (London: Routledge, 2002), 145–68. -
Tobacco Control Policy Strategies, Successes, and Setbacks
ARCHIV WAVERL no. 118483 Tobacco Control Policy STRATEGIES SUCCESSES & SETBACKS Edited by Joy de Beyer and Linda Waverley Brigden Tobacco Control Policy Strategies, Successes, and Setbacks Edited by Joy de Beyer and Linda Waverley Brigden • ritc rmct . A copublication of the World Bank and Research for InternationalTobacco Control (RITC) AIZ(!4!\ Copyright© 2003 The InternationalBank for Reconstructionand Development / The World Bank 1818 H StreetNW Washington, DC 20433, USA and The International Development Research Centreon behalfof the Research for International TobaccoControl Secretariat P.O. Box 8500, Ottawa,Ontario, Canada, K1G 3H9 All rights reserved. 1 2 3 4 06 05 04 03 The findings, interpretations, and conclusions expressed herein are those of the author(s) and do not necessarily reflect the views of the Board of Executive Directors of the WorldBank or the governmentsthey represent. Neither the World Bank nor IDRC/RITC guarantees the accuracyof the data in- cluded in this work. The boundaries,colors, denominations,and other informa- tionshown on any map in this work do not imply any judgmenton thepart of the World Bank or IDRC/RITC concerning the legal status of any territoryor the en- dorsementor acceptance of such boundaries. Rights and Permissions The materialin this work is copyrighted. Copying and/or transmittingportions or all of this work without permissionmay be a violationof applicable law. The World Bankand IDRC/RITC encourage dissemination of their work andwill nor- mally grant permissionpromptly. For permission to photocopy or reprint any part of this work, please send a request with complete information to the Copyright Clearance Center, Inc., 222 RosewoodDrive, Danvers, MA 01923, USA, telephone 978-750-8400, fax 978-750-4470,www.copyright.com. -
Early Development of Total Hip Replacement
EARLY DEVELOPMENT OF TOTAL HIP REPLACEMENT The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 14 March 2006 Edited by L A Reynolds and E M Tansey Volume 29 2006 ©The Trustee of the Wellcome Trust, London, 2007 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2007 The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 085484 111 0 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as: Reynolds L A, Tansey E M. (eds) (2007) Early Development of Total Hip Replacement. Wellcome Witnesses to Twentieth Century Medicine, vol. 29. London: Wellcome Trust Centre for the History of Medicine at UCL. CONTENTS Illustrations and credits v Abbreviations ix Witness Seminars: Meetings and publications; Acknowledgements E M Tansey and L A Reynolds xi Introduction Francis Neary and John Pickstone xxv Transcript Edited by L A Reynolds and E M Tansey 1 Appendix 1 Notes on materials by Professor Alan Swanson 95 Appendix 2 Surgical implant material standards by Mr Victor Wheble 97 Appendix 3 Selected prosthetic hips 101 References 107 Biographical notes 133 Glossary 147 Index 155 ILLUSTRATIONS AND CREDITS Figure 1 Site of a total hip transplant. Illustration provided by Ms Clare Darrah. 4 Figure 2 Mr Philip Wiles FRCS, c. 1950. Illustration provided by Sir Rodney Sweetnam. 5 Figure 3 X-ray of Wiles’ hip, c.