DOCSLIB.ORG

(12) United States Patent (10) Patent No.: US 9,668,948 B2 Klingman (45) Date of Patent: *Jun

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
(12) United States Patent (10) Patent No.: US 9,668,948 B2 Klingman (45) Date of Patent: *Jun USOO9668948B2 (12) United States Patent (10) Patent No.: US 9,668,948 B2 Klingman (45) Date of Patent: *Jun. 6, 2017 (54) PRODUCTS AND METHODS FOR A 6LX 9/70 (2006.01) REDUCING MALODOR FROM THE A61O 15/00 (2006.01) PUDENDUM A6IR 8/49 (2006.01) (52) U.S. Cl. (71) Applicant: Shannon Elizabeth Klingman, Chaska, CPC ............ A61K 8/0208 (2013.01); A61K 8/365 MN (US) (2013.01); A61K 9/0034 (2013.01); A61 K 9/7007 (2013.01); A61O 15/00 (2013.01); (72) Inventor: Shannon Elizabeth Klingman, Chaska, A61 K 8/4953 (2013.01) MN (US) (58) Field of Classification Search None (*) Notice: Subject to any disclaimer, the term of this See application file for complete search history. patent is extended or adjusted under 35 U.S.C. 154(b) by 0 days. (56) References Cited This patent is Subject to a terminal dis- U.S. PATENT DOCUMENTS claimer. 2008/0050398 A1* 2, 2008 Bockmuehl ........ A61K 38/1709 (21) Appl. No.: 15/015, 197 424,190.1 (22) Filed: Feb. 4, 2016 OTHER PUBLICATIONS (65) Prior Publication Data K. Ara et al., “Foot odor due to microbial metabolism and its control.” Canadian Journal of Microbiology, Apr. 2006:52 (4):357 US 2016/O151257 A1 Jun. 2, 2016 64, abstract only from Pubmed: https://www.ncbi.nlm.nih.gov/ pubmed/16699586. Related U.S. Application Data (Continued) (63) Continuation-in-part of application No. 14/613,420, filed on Feb. 4, 2015, which is a continuation of Primary Examiner Ernst N Arnold application No. 12/875,123, filed on Sep. 2, 2010, Assistant Examiner — Kyung Sook Chang now abandoned, application No. 15/015,197, filed on (74) Attorney, Agent, or Firm — Jeffrey D. Lindsay Feb. 4, 2016, which is a continuation-in-part of application No. 14/604,733, filed on Jan. 25, 2015, (57) ABSTRACT now. Pat No. 9,566,223, which is a continuation of Products and methods are disclosed for reducing the pro application No. 127823,834, filed on Jun. 25, 2010, duction of unwanted odors from the pudendum. The prod now Pat. No. 8,992,898, application No. 15/015,197, ucts include an acidifying composition comprising one or filed on Feb. 4, 2016, which is a continuation of more carboxylic acids such as mandelic acid or salts thereof (Continued) and Xanthine compounds such as caffeine or salts thereof. The methods include application of the products to the (51) Int. Cl. pudendum in any of a variety of ways to effectively reduce A6 IK 8/02 (2006.01) unwanted odors. A6 IK 8/365 (2006.01) A6 IK 9/00 (2006.01) 19 Claims, 7 Drawing Sheets US 9,668,948 B2 Page 2 Related U.S. Application Data application No. 12/875,123, filed on Sep. 2, 2010, now abandoned. (60) Provisional application No. 61/309,831, filed on Mar. 2, 2010, provisional application No. 61/289.992, filed on Dec. 23, 2009, provisional application No. 61/325,317, filed on Apr. 17, 2010. (56) References Cited OTHER PUBLICATIONS A. Zech et al., “The quantitative distribution of percutaneously applied caffeine in the human skin.” Archives of Dermatology Research, Nov. 1979, 266(3): 277-283. URL: https://www.ncbi.nlm. nih.gov/pubmed/526050. S. Trauer et al., “Permeation of topically applied caffeine through human skin—a comparison of in vivo and in vitro data, British Journal of Clinical Pharmacology, Aug. 2009; 68(2): 181-186: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767280/. * cited by examiner U.S. Patent Jun. 6, 2017 Sheet 1 of 7 US 9,668,948 B2 24 FIG. 1C U.S. Patent Jun. 6, 2017 Sheet 2 of 7 US 9,668,948 B2 FIG. 2 U.S. Patent Jun. 6, 2017 Sheet 3 of 7 US 9,668,948 B2 FIG. 3 U.S. Patent Jun. 6, 2017 Sheet 4 of 7 US 9,668,948 B2 FIG. 4 U.S. Patent Jun. 6, 2017 Sheet S of 7 US 9,668,948 B2 g - 3. s 8. th ess - i. ES, --- 0 S S g e FIG 5A { S. - 8 s as 3.3 als s \ s t Gs-s { --- ---0 U.S. Patent Jun. 6, 2017 Sheet 6 of 7 S. 3. r 3. s s 3. s s -- - s --" -- : --- 1 : s m , aw' is 3. s S. 8. - i. FIG.^ 6As ES te a -------- t s S w -F=- H ==- s 2. S. & s S. X is FIG. 6B U.S. Patent Jun. 6, 2017 Sheet 7 Of 7 US 9,668,948 B2 it Stasia: Ei e FIG 7A Stasia fe: setta US 9,668,948 B2 1. 2 PRODUCTS AND METHODS FOR with reactions from bacteria, but the historic focus on REDUCING MALODOR FROM THE bacteria in the vagina and the assumption that vaginitis or PUDENDUM more specifically, bacterial vaginosis, is the cause of the odor may have misled many in seeking for solutions that CLAIM TO PRIORITY treat bacteria in the vagina. We have found that for many women, the source of the This application claims priority to U.S. patent application odor is more commonly from the pudendum (including the Ser. No. 14/613,420, “Products and Methods for Reducing intergluteal folds and external genitalia), where anaerobic Malodor from the Pudendum,” filed Feb. 4, 2015 by Shan bacteria from the lower gastrointestinal (GI) tract or other non Klingman, which claims priority to U.S. patent appli 10 Sources can be found. These anaerobic bacteria may be cation Ser. No. 12/875,123, “Products and Methods for especially present on the external skin around the perianal Reducing Malodor from the Pudendum, filed Sep. 2, 2010 anatomy. by Shannon Klingman, which in turn claims priority to both The new recognition that vaginal bacteria are not cause of U.S. patent application Ser. No. 61/309,831, “Products and fishy odor in many women is of special significance, and Methods for Reducing Malodor from the Pudendum, filed 15 Mar. 2, 2010 by Shannon Klingman, and U.S. patent appli helps explain why antibiotic treatments and other standard cation Ser. No. 61/289.992, “Products and Methods for treatments have fared so poorly in treating many cases of Reducing Malodor from the Pudendum,” filed Dec. 23, 2009 fishy odor, and why may women presenting symptoms of by Shannon Klingman; and also claims priority to U.S. fishy odor do not actually have bacterial vaginosis when patent application Ser. No. 14/604.733, “Antiperspirants and thorough testing is conducted (see, for example, N. K. Lowe Deodorants, filed Jan. 25, 2015, which in turn claims et al., “Accuracy of the Clinical Diagnosis of Vaginitis priority to U.S. patent application Ser. No. 12/823,834, Compared With a DNA Probe Laboratory Standard.” “Antiperspirants and Deodorants, filed Jun. 25, 2010, Obstetrics & Gynecology, vol. 113, no. 1, January 2009, pp which claims priority to U.S. patent application Ser. No. 89-95, abstract available online at http://journals.lww.com/ 61/325,317, “Improved Antiperspirant,” filed Apr. 17, 2010; 25 greenjournal/Abstract/2009/01000/ all of which are hereby incorporated by reference in their Accuracy of the Clinical Diagnosis of Vaginitis. 15.aspx entireties for all purposes. and Hope K. Haefner, “Conquering Resistant Vulvovagini tis.” 2007, presentation available online at http://www.yel BACKGROUND lowdocuments.com/12180308-advancements-in-benign 30 Vulvar-and). It also points to the long unmet need for Field of the Invention improved means of reducing or preventing fishy odor by This invention pertains to products and methods for better controlling the activity of anaerobic bacteria on the personal care and odor control, particularly for reducing or pudendum, particularly those interacting with or feeding on preventing unwanted odor from the pudendum. nitrogen compounds in body fluids such as semen, blood, Description of Related Art 35 urine, and feces. Fishy odors from the pudendal region or genitalia of the It is believed that a particularly significant discovery is the female body have long been a source of annoyance and recognition that the Source of a fishy odor for many women embarrassment to adult and teenaged women. Women seek is not bacteria in the vagina, nor bacteria coming from the ing help from physicians are frequently given antibiotics vagina, but anaerobic bacteria from non-vaginal sources Such as metronidazole, based on the long-standing belief 40 Such as the gastrointestinal tract. An understanding of this that vaginal bacteria are the cause of the problem. Indeed, a discovery can be enhanced in part by consideration of a rare fishy odor is commonly considered to be a symptom for metabolic disorder, trimethylaminuria, a disorder occurring bacterial vaginosis (see, for example, "Bacterial Vaginosis.” when humans have an impaired version of the enzyme Wikipedia, http://en.wikipedia.org/wiki/Bacterial vagino flavin-containing monooxygenase 3 (FMO3), which con sis, accessed Nov. 17, 2009). Others seeking relief have tried 45 verts trimethylamine to trimethylamine N-oxide during the a variety of products such as douches which may provide metabolism of some nitrogen-containing compounds such as only short-term decrease in the odor (if the vagina was the choline or phosphocholine. With impaired FMO3 activity, actual source of the odor). In spite of many medications and trimethylamine concentrations become elevated and strong feminine hygiene products, there has been a long-standing fishy odor can be generated by the sweat and other body unmet need in this area, fueled by lack of understanding 50 fluids of a person, making life difficult and painful. Foods about the causes and the nature of the problem, especially rich in choline are especially problematic for those with the assumption that fishy odor only arises from the vagina trimethylaminuria, since it leads to production of large due to bacterial imbalance or infectious cause Such as amounts of trimethylamine.
Load more

Recommended publications
  • Characterization of Human Body Odor and Identification of Aldehydes Using Chemical Sensor
    Rev Anal Chem 2017; 36(2): 20160028 Sunil Kr. Jha* Characterization of human body odor and identification of aldehydes using chemical sensor DOI 10.1515/revac-2016-0028 to several chemical classes, including aldehyde, acid, Received April 27, 2016; accepted November 1, 2016; previously amine, alcohol, hydrocarbon, ketones, sterols, sulfur published online December 21, 2016 compounds, and terpenoids, generating human body odor (Amoore 1977, Fang et al. 1998, Toan et al. 1999, Abstract: Human body odor is a unique identity feature of Clancy and McVicar 2002, Jain 2004, Statheropoulos individual as well as an established composite of numer- et al. 2005, Havlicek and Lenochova 2006, Steeghs ous volatile organic compounds (VOCs) belonging to sig- et al. 2006, Wedekind et al. 2006, Penn et al. 2007, nificant chemical classes. Several analytical methods have D’Amico et al. 2008b, Preti and Leyden 2010, Wisthaler been used in the characterization of human body odor in and Weschler 2010, Yamazaki et al. 2010, Seeley et al. order to recognize the chemical composition of VOCs in 2011, Thorn and Greenman 2012, Agapiou et al. 2015a,b, medical, forensic, and biometric applications. Besides, Buljubasic and Buchbauer 2015, Sorokowska et al. 2015, real-time sensing systems (based on the chemical sensors) Allen et al. 2016, Colón-Crespo et al. 2016, Fialová et al. are being researched and developed for qualitative and 2016, Gildersleeve et al. 2016, Prokop-Prigge et al. 2016, quantitative recognition of VOCs in body odor. The pre- Sorokowska et al. 2016, Stefanuto and Focant 2016, sent review focuses the state-of-the-art research outcomes Verhulst et al.
    [Show full text]
  • Mosquito Host Seeking in 3D Using a Versatile Climate-Controlled Wind Tunnel System
    METHODS published: 11 March 2021 doi: 10.3389/fnbeh.2021.643693 Mosquito Host Seeking in 3D Using a Versatile Climate-Controlled Wind Tunnel System Annika Hinze 1, Jörgen Lantz 2, Sharon R. Hill 1,3 and Rickard Ignell 1,3* 1 Disease Vector Group, Chemical Ecology, Department of Plant Protection Biology, Swedish University of Agricultural Sciences, Alnarp, Sweden, 2 Jörgen Lantz Engineering Consulting Firm, Alnarp, Sweden, 3 Max Planck Centre Next Generation Chemical Ecology, Uppsala, Sweden Future anthropogenic climate change is predicted to impact sensory-driven behaviors. Building on recent improvements in computational power and tracking technology, we have developed a versatile climate-controlled wind tunnel system, in which to study the effect of climate parameters, including temperature, precipitation, and elevated greenhouse gas levels, on odor-mediated behaviors in insects. To establish a baseline for future studies, we here analyzed the host-seeking behavior of the major malaria vector mosquito, Anopheles gambiae sensu strico, to human odor and carbon dioxide (CO2), under tightly controlled climatic conditions, and isolated from potential background contamination by the presence of an experimenter. When presented with a combination Edited by: Bart R. H. Geurten, of human foot odor and CO2 (case study I), mosquitoes engaged in faster crosswind University of Göttingen, Germany flight, spent more time in the filamentous odor plume and targeted the odor source more Reviewed by: successfully. In contrast, female An. gambiae s. s. presented with different concentrations Merid Negash Getahun, International Centre of Insect of CO2 alone, did not display host-seeking behavior (case study II). These observations Physiology and Ecology (ICIPE), Kenya support previous findings on the role of human host-associated cues in host seeking Ivan V.
    [Show full text]
  • Evaluation of 2-Butanone As a Substitute for Carbon Dioxide In
    EVALUATION OF 2-BUTANONE AS A SUBSTITUTE FOR CARBON DIOXIDE IN MALARIA MOSQUITO ATTRACTANTS MBURU MONICAH MIRAI (B.Sc. Hons, University of Nairobi) A THESIS SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF THE MASTER OF SCIENCE IN APPLIED PARASITOLOGY DEGREE OF THE UNIVERSITY OF NAIROBI SCHOOL OF BIOLOGICAL SCIENCES JULY 2013 i DECLARATION I, Monicah Mirai Mburu, declare that this is my original work and it has not been presented for a degree in any other university. Candidate: Mburu Monicah Mirai Signature ; Date Supervisors: This thesis has been submitted with our approval as supervisors. Signature ; Date Prof. Wolfgang Richard Mukabana School of Biological Sciences, University of Nairobi, Nairobi, Kenya; and International Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya Signature ; Date Dr. James Mutunga International Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya ii DEDICATION To the family of Mr. and Mrs. Gabriel Mburu as well as Miss Dorothy Wambui. iii ACKNOWLEDGEMENTS I wish to acknowledge the support and help of the people who contributed to the completion of this work. I owe my deepest gratitude to my supervisors, Prof. Wolfgang Richard Mukabana and Dr. James Mutunga for their time, invaluable support, guidance and enthusiastic encouragement that was vital to the completion of this project. Their useful research critiques, valuable and constructive suggestions and corrections from initial to final levels enabled me develop an understanding and interest in malaria research thereby completing this work. I wish to acknowledge the School of Biological sciences, University of Nairobi for its contribution in the development of this work.
    [Show full text]
  • Bioprospecting for Anti-Mosquito Phytochemicals Associated with Olfaction and Larvicidal Activities from Selected Kenyan Plants
    i BIOPROSPECTING FOR ANTI-MOSQUITO PHYTOCHEMICALS ASSOCIATED WITH OLFACTION AND LARVICIDAL ACTIVITIES FROM SELECTED KENYAN PLANTS . JOHN BWIRE OCHOLA (MSc. B.Sc.) I84/27752/2013 A THESIS SUBMITTED IN FULFILMENT OF THE REQUIREMENT FOR THE AWARD OF THE DEGREE OF DOCTOR OF PHILOSOPHY (CHEMISTRY) IN THE SCHOOL OF PURE AND APPLIED SCIENCE OF KENYATTA UNIVERSITY JANUARY 2020 ii DECLARATION I certify that this thesis is my original work and has not been presented for award of a degree in any other university. Besides where due acknowledgement has been made, the work is the result of my labour which has been accomplished from the commencement date of the permitted studies application. Signature ……………………………… Date ………………………………… John Bwire Ochola Reg I84/27752/2013 Department of Chemistry Declaration by supervisors We confirm that the work reported in this thesis was carried out by the student under our supervision and has been submitted for examination with our approval as supervisors Signature ……………………………………. Date …………………… Prof. Ahmed Hassanali Department of Chemistry, Kenyatta University, Nairobi, Kenya Signature ……………………………………. Date …………………… Dr. Wilber Lwande Applied Bioprospecting Programme International Centre of Insect Physiology and Ecology, Nairobi, Kenya. Signature ……………………………………. Date …………………… Dr. Barbara Frei Haller Institute of Pharmaceutical Sciences, ETH Zurich Switzerland iii DEDICATION “To my wife Jackline and sons, Nathan, Seth, Lawrence and Ronnie, you kept my spirit alive.” iv ACKNOWLEGDEMENTS I express my sincere gratitude to Dr Wilber Lwande of ICIPE, Prof. Ahmed. Hassanali of the Department of Chemistry, Kenyatta University and Dr. Barbara Frei Haller of the Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland for their support and mentorship throughout the research period and in the writing of this thesis.
    [Show full text]
  • Embarrassing Foot Odor?
    Just ONE Application PediLux4™ is the unique new solution ™ to foot odor! Stop the Stink! PediLux4™ is the only single-use treatment for For Up to 90 Days with New Embarrassing bromhidrosis caused by the foul-smelling combination of sweat, bacteria and fungus. Unlike other over-the- Foot Odor? counter products that treat just the symptoms and not the cause, PediLux4™ attacks the source of the Deodorizing Foot Cream ™ odor, changing the skin’s environment to make it more ™ difficult for bacteria to reproduce. #1 Doctor-recommended product Stop the Stink! How does it work? • Easy to use For Up to 90 Days with New PediLux4™ utilizes zinc oxide as a base and is applied in • Works immediately conjunction with special all-cotton socks. The cream is • Guaranteed effective rubbed into the feet, especially between and under toes. The socks are worn for 8 hours, or overnight. • Available without a prescription A single treatment of PediLux4™ will last up to three months ™ and leave feet feeling fresh “As a professional I have spent many years dealing and smelling clean. with foot problems. I was completely shocked when Deodorizing I found out PediLux4 is just that simple. With one Foot Cream application the whole family immediately noticed the results. Two and half months out from one application now and it continues with good results. I am excited to have this available for my patients.” — Paul Clint Jones, DPM, Instep Foot and Ankle Recommended by/Available from: In addition to Bromhidrosis, PediLux4™ is also helpful for sufferers of hyperhidrosis (excessive sweating) as it includes anti-inflammatory agents that can help minimize sweating.
    [Show full text]
  • Development of Deodorizing Agent from Natural Plant Extracts
    Development of deodorizing agent from natural plant extracts Taek Kyu Jung, Hyun-Chul Park, Kyung-Sup Yoon Saimdang Cosmetics Co., Ltd., R&D Center, 143, Yangcheongsongdae-gil, Ochang-eup, Cheongwon-gu, cheongju-si, Chungcheongbuk-do, Korea Keywords: Deodorizing, Plant extract, Isovaleric acid, Anti-microbial effect, Leusine dehydrogenase Short Summary There are many kinds of unpleasant odor in our daily life, such as body odor caused by metabolism and aging. According to recent studies, it is known that there are various kinds of odor-causing substances such as steroids, fatty acids, sulfur compounds, aldehydes, ester, ketones, and nitric compounds. Also, one of the causes of odor generation is thought to be microbiologically produced from precursors contained in the apocrine secretions. The aim of this study was to investigate the antiperspirant and deodorant of natural plant extracts for the representative odor substances such as isovaleric acid, ammonia and nonenal. Also, we were to investigate the antimicrobial effect for skin microbes and the leucine dehydrogenase inhibition effect of plant extracts. Introduction The generation of odor on various sites on the human body, e.g. foot, mouth, or axilla, is mainly caused by microbial transformation of odorless natural skin secretions into volatile odorous molecules. Thus, identification of the primary components in each body odor and clarification of the mechanisms of their generation are important for the development of methods to effectively control such odors [1]. The factor influencing human body odors were skin bacteria, life style, environmental factor (heat and humidity), physiological factors (age, gender), genetics and ethnicity, emotional factor and clinical disorders. Also, a wide range of volatile odorous substances has been implicated in axillary odor and is thought to be microbiological produced from precursors contained in the apocrine secretions [2-4].
    [Show full text]
  • Foot Odor, Known in the Medical Profession As Bromhidrosis, Can Be
    Foot odor, known in the medical profession as bromhidrosis, can be traced to bacteria that find your moist and warm feet, socks, and shoes the perfect place to breed and multiply. Thousands of sweat glands on the soles of the feet produce perspiration composed of water, sodium chloride, fat, minerals, and various acids that are the end products of your body's metabolism. In the presence of certain bacteria (namely those found in dark, damp shoes), these sweaty secretions break down, generating the stench that turns people green. Wash well. Those sweat glands on the soles of your feet produce perspiration composed of water, sodium chloride, fat, minerals, and various acids that are end products of your body's metabolism. In the presence of certain bacteria, these sweaty secretions break down, generating a foul smell. Washing away the bacteria with deodorant soap (and drying them well) will short-circuit this process. How often should you wash your feet? Enough to remove the offending bacteria but not so often that you remove all the protective oils from your skin. For strong foot odor, you may need to bathe your feet several times a day. However, if you notice that your feet are becoming scaly and cracked, cut back on the number of washings. Salt your tootsies. For extra-sweaty feet, try adding half a cup of kosher salt (it has larger crystals than ordinary table salt) to a quart of water and soaking your feet in the solution. After soaking, don't rinse your feet; just dry them thoroughly. As anyone who has ever taken a dip in the ocean likely knows, salt has a drying effect on the skin.
    [Show full text]
  • ABSTRACT PICKETT, TYLER EUGENE. Correlating The
    ABSTRACT PICKETT, TYLER EUGENE. Correlating the Perception of Foot Odor and the Amount of Odorous Chemicals Present in Footwear Materials. (Under the direction of Dr. R. Bryan Ormond). Foot odor is capable of determining the lifespan of textiles in the footwear industry. To combat the problem, industry leaders have begun creating various solutions, such as treatments and finishes on the shoe’s surfaces and fibers. The recent uptick in antimicrobial and anti-odor finishes has created the need for odor-relief efficacy assessments. Over the last year, a research effort has been made to develop such a test. The combination of odor panels, human wear trials, newly developed air sampling methods, and quantitative chemical analysis have all been combined to provide a correlation between the odor that a population of subjects has perceived in human-worn shoes and the detected amounts of key odor compounds sampled from the same shoes. Research has suggested that there are key odor compounds responsible for the perception of foot odor. Three of the major compounds include: acetic acid, propionic acid, and isovaleric acid. An analytical method using gas chromatography with a flame ionization detector (GC-FID) was developed to detect and quantify low odor concentrations of the three major compounds. A closed-system air sampling method was developed for the capture of acetic, propionic, and isovaleric acids. The intent was to create an easy-to-use, non-destructive, affordable method for repeatable use on shoes over a long period of time. The targeted odor compounds were caught by an open silica-gel sorbent bed and extracted by an acetone solvent.
    [Show full text]
  • Development of Anti-Odour and Super Moisture Absorbent Socks S
    23922 S. Grace Annapoorani/ Elixir Tex. & App. Design 70 (2014) 23922-23925 Available online at www.elixirpublishers.com (Elixir International Journal) Textiles and Apparel Design Elixir Tex. & App. Design 70 (2014) 23922-23925 Development of anti-odour and super moisture absorbent socks S. Grace Annapoorani Department of Textiles and Apparel Design, Bharathiar University, Coimbatore-46, Tamil Nadu, India. ARTICLE INFO ABSTRACT Article history: The foot is among the heaviest producers of sweat in the body, as it is able to produce over Received: 11 March 2014; 1 US pint (0.47 l) of perspiration per day. Socks help to absorb this sweat and draw it to Received in revised form: areas where air can evaporate the perspiration. Although perspiration is odorless and 99% 23 April 2014; water, it provides a perfect medium for bacteria to grow. The bacteria cause foot odour. Accepted: 2 May 2014; Foot odour is a type of body odour that affects the feet of humans and is generally considered to be an unpleasant smell. Wearing polyester or nylon socks may increase Keywords perspiration and therefore may intensify foot odor. In order to overcome this problem, a Anti-odour, nylon sock was with increased moisture absorbency. The super absorbent solution was Super Absorbent, prepared by using various chemicals. Then the solution was examined for antibacterial Foot, activity by well diffusion method. The nylon socks were treated with this solution by dip Socks. dry method. The finished sample shows good moisture absorbency and also having antimicrobial activity when compared with the untreated sample by the testing method AATCC (147 and 30).
    [Show full text]
  • Global Change and Human Vulnerability to Vector-Borne Diseases
    GLOBAL CHANGE AND HUMAN VULNERABILITY TO VECTOR-BORNE DISEASES Topic Editors Rubén Bueno-Marí and Ricardo Jiménez-Peydró PHYSIOLOGY GENETICS FRONTIERS COPYRIGHT STATEMENT ABOUT FRONTIERS © Copyright 2007-2013 Frontiers is more than just an open-access publisher of scholarly articles: it is a pioneering Frontiers Media SA. All rights reserved. approach to the world of academia, radically improving the way scholarly research is managed. All content included on this site, The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share such as text, graphics, logos, button and generate knowledge. Frontiers provides immediate and permanent online open access to all icons, images, video/audio clips, downloads, data compilations and its publications, but this alone is not enough to realize our grand goals. software, is the property of or is licensed to Frontiers Media SA (“Frontiers”) or its licensees and/or subcontractors. The copyright in the FRONTIERS JOURNAL SERIES text of individual articles is the property of their respective authors, The Frontiers Journal Series is a multi-tier and interdisciplinary set of open-access, online subject to a license granted to Frontiers. journals, promising a paradigm shift from the current review, selection and dissemination The compilation of articles processes in academic publishing. constituting this e-book, as well as All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service all content on this site is the exclusive property of Frontiers. to the scholarly community. At the same time, the Frontiers Journal Series operates on a revo- Images and graphics not forming lutionary invention, the tiered publishing system, initially addressing specific communities of part of user-contributed materials may not be downloaded or copied scholars, and gradually climbing up to broader public understanding, thus serving the interests without permission.
    [Show full text]
  • The Cowl, November 10, 1983 NEWS
    mm PC SOCCER FORUM ON WOMAN RANKED 11th. SEXUALITY TO TAKE IN NATION PLACE NEXT WEEK See Story Page 12 See Story On Page 10 VOL. X X X V III NO. 11_________________ PROVIDENCE COLLEGE, PROVIDENCE, R.I.___________________ N O VEM BER 10, 1983 Congressional News Friars Club To Assess Their Role At PC by Kathy Bisegna lion with or jurisdiction over the Friars Club, both organizations Rev. Phillip Smith, O.P. open­ will work for the enhancement of ed the November 7, Student Con­ student involvement at Pro­ gress meeting with a prayer and a vidence College. In the spirit of short talk. this cooperation, these student During his talk Fr. Smith groups seek to foster the goals of wanted to commend students for PC and the best interests o f the their support of last week’s students. “ President’s Forum on Culture In other business, Rev. John A. and Values" which featured Gary McMahon, O.P., sent a letter to Wills. He said that the success of the Student Congress to thank the forum is leading the way for them for naming the 'Person of another such presentation in the the Year' award in his honor. In spring. his letter, Fr. McMahon said that The Student Congress - BOP - finding the proper words to thank Friars Club Wheelchair Race is Congress was difficult. McMahon slated for Sunday, November 20. said that he was "flabbergasted by The race will run from the Rhode such an honor.” Island State House to Colonel’s Lifestyles committee chairper­ Corner and is to benefit Meeting son Tracey Lynch, announced the Street School.
    [Show full text]
  • Plasmodium-Associated Changes in Human Odor Attract Mosquitoes
    Plasmodium-associated changes in human odor PNAS PLUS attract mosquitoes Ailie Robinsona,1, Annette O. Busulab,c,2, Mirjam A. Voetsb, Khalid B. Beshira, John C. Caulfieldd, Stephen J. Powerse, Niels O. Verhulstb,3, Peter Winskillf, Julian Muwanguzia, Michael A. Birkettd, Renate C. Smallegangeb, Daniel K. Masigag, W. Richard Mukabanah,i, Robert W. Sauerweinj, Colin J. Sutherlanda, Teun Bousemaa,j, John A. Pickettd,1,4, Willem Takkenb, James G. Logana,1, and Jetske G. de Boerb,1,5 aFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, WC1E 7HT London, United Kingdom; bLaboratory of Entomology, Wageningen University & Research, 6708 PB Wageningen, The Netherlands; cHuman Health, International Centre of Insect Physiology and Ecology, Nairobi, Kenya; dBiointeractions and Crop Protection, Rothamsted Research, Harpenden, AL5 2JQ Hertfordshire, United Kingdom; eComputational and Analytical Sciences, Rothamsted Research, Harpenden, AL5 2JQ Hertfordshire, United Kingdom; fMRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, W2 1NY London, United Kingdom; gAnimal Health, International Centre of Insect Physiology and Ecology, Nairobi, Kenya; hSchool of Biological Sciences, University of Nairobi, Nairobi, Kenya; iDepartment of Production Ecology, Science for Health, Nairobi, Kenya; and jMedical Microbiology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands Contributed by John A. Pickett, March 14, 2018 (sent for review December 13, 2017; reviewed by David L. Denlinger and Ana Rivero) Malaria parasites (Plasmodium) can change the attractiveness of their (CHMI), with a variable effect on attractiveness (21). While vertebrate hosts to Anopheles vectors, leading to a greater number increased attractiveness of Plasmodium-infected individuals of vector–host contacts and increased transmission.
    [Show full text]