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Informed 74 The newsletter of the Hepatitis B Foundation Fall 2018 Inside this issue Hepatitis B Foundation Launching 2 3 NewHep B Vice Cure Presidents Campaign Named Effort to Improve Patient Access Grows Momentum to Hepatitis B Medications 5 Hepatitis B Foundation to

Provide Resources for African 5 Immigrant Communities 7 Focus on Hepatitis Delta or many people with chronic hepatitis B, Provider Profile: Dr. Su Wang Fthe cost of antiviral medications is a major barrier to treatment. Even those who have prescription coverage can face co-pays that put page 6 medication out of reach. 6th Hep B United Summit

While U.S. health insurance through “adverse tiering” to discourage plans must cover people living with Florida’s 2018 healthcare marketplace. hepatitis B, many plans place hepatitis OurQualified research Health revealed Plans thatsold commonthrough their plans. The complaint was based B medications in a category that hepatitis B medications were placed on people living with HIV from buying dramatically increases the co-pays for the highest two tiers in the majority of available in 2014 and 2015, and found those drugs. Although current laws the plans. These tiers typically required thaton Florida four of Qualified the insurance Health plans Plans they protect individuals with pre-existing patients to meet deductibles between conditions including hepatitis B, from $2,500 and $6,750 before allowing highest tier, leading to inordinately discriminatory practices by health highreviewed co-payments placed all and HIV co-insurance drugs on the for insurance companies, these prescription drugs, even generics. This over-pricing medications used in the treatment of pricing practices have effectively made ofcost-sharing certain drugs benefits by placing for any them hepatitis in a B many insurance plans unaffordable for higher tier, called “adverse tiering,” acts people living with hepatitis B. as a deterrent for people with chronic HIV and AIDS. The practice was found When health insurers design plans, conditions from buying a health plan, to be discriminatory by the Department they assign each prescription drug and can be considered discriminatory of Health and Human Service’s Office to a price “tier.” A low-cost generic against pre-existing conditions. revisedfor Civil toRights. be more The affordable, insurers were but thisfined antibiotic may be a Tier 1 while a “adverseand the drug tiering” tiers persists for HIV nationwidedrugs were for new, brand-name drug is assigned to hepatitis B and C drugs. To fight these practices, The AIDS a pricier Tier 4 or 5. The Hepatitis B Continues on page 3 » Foundation recently reviewed hepatitis FloridaInstitute against and the insurance National companiesHealth Law B prescription coverage for Silver-Level Program (NHeLP) filed complaints in

that inflated their HIV drug prices The Hepatitis B Foundation is a national nonprofit organization dedicated to finding a cure and improving the quality of life for those affected by hepatitis B worldwide through research, education and patient advocacy. Hepatitis B Foundation and Baruch S. Blumberg Institute Improved Patient Access, continued… Name New Vice Presidents for Research Affairs, 3805 Easton Road Filing a Hepatitis B Drug « Continues from page 1 email at [email protected] to share their Institutional Advancement, and Public Health and Programs Pricing Complaint  www.hepb.orgDoylestown, [email protected] PA 18902 Our research uncovered additional story. he Hepatitis B Foundation and the Baruch S. Community College Foundation for 13 years, Phone: (215) 489-4900 The Hepatitis B Foundation is a national T during which she built the college’s major nonprofit organization dedicated to finding a consumer protection laws that apply Who can file a complaint? that Ju-Tao Guo, MD has been named vice gifts, corporate grants, annual fund, and donor cure and improving the quality of life for those affected by hepatitis B worldwide through whenbarriers hepatitis to hepatitis B treatments B treatment. and otherIn to insuranceIn addition, plans there purchased are federal on the Anyone can file a complaint at president,Blumberg research Institute affairs, are pleasedJean Holmes to announce, MBA relations programs. She has been deeply research, education and patient advocacy. drugsaddition are to placed these onfinancial high tiers, barriers, this marketplace, as well as Medicare and any time. You do not have to be a has joined the organization as vice president, involved as a volunteer in her community, Board of Directors often requires prior authorization, Medicaid. We encourage patients with hepatitis B patient or a purchaser/ institutional advancement, and Chari Cohen, serving on numerous committees with the Chairman – Joel Rosen, Esq President – Timothy Block, PhD quantity limits, or the use of specialty one of these insurance plans, who holder of the insurance plan to file DrPH, MPH has been named vice president, Lower Bucks Chamber of Commerce and Vice President – Catharine Williams pharmacies, which further discourage are facing high costs for medication, an administrative complaint with public health and programs. Greater BucksMont Chamber of Commerce, Treasurer – Joseph Hediger your state Bureau of Insurance or and currently serves on the board of directors Secretary – Janine Witte Stanley Broadbent the case of Florida, area coverage also the federal civil rights office. for the Youth Orchestra of Bucks County. A Nathaniel Brown, MD users from accessing treatment. In Theto file Foundation, complaints in with collaboration their state’s researchIn his newundertaken position, member of the Association of Fundraising Carol Brosgart, MD How do I file the complaint? Loren Danzis, Esq in Florida, Blue Cross Blue Shield is the Health Insurance Commissioner. byDr. scientistsGuo will oversee at the all Craig Esterly Each state’s Bureau of Insurance poses an issue. In 21 of the 67 counties and a template for consumers and with them as a mentor and has been a Anthony Ford-Hutchinson, PhD website should have a portal Professionals since 2005, she has participated David Gruber, CPA additional 22 counties, only two carriers with NHeLP, has created instructions Raman Kapur only carrier offering coverage. In an for filing a complaint. Usually Blumberg Institute. at LaSalle. Thomas Shenk, PhD offer coverage. Thus, while some plans which can be found at hepb.org/ as the W. Thomas organizations to use to file complaints, you can copy and paste the Dr. Guo has served conference presenter for the Nonprofit Center Walter Tsou, MD, MPH offer better coverage and cost-sharing overpricing. Consumers will have to As vice president, Su Wang, MD, MPH, FACP completed complaint into a form public health and Wayne Yetter, MBA do some research on the marketplace’s on the website, or you can email Ju-Tao Guo, MD London Distinguished Executive Vice President/Chief Operating Officer: a limited ability to choose the best plan website to discover the drug prices the complaint to the Bureau of Professor and Chairman Louis P. Kassa, III, MPA for theirspecific needs. medications, patients have in their region, but they can help end Experimental Therapeutics at Baruch S. will be responsible Vice President, Public Health and Programs: Insurance. of Department of forprograms, building Dr. and Cohen Chari Cohen, DrPH, MPH The Hepatitis B Foundation is discrimination and bring down the For detailed instructions on medical training in Lanzhou University School expanding programs Vice President, Institutional Advancement: working to change these practices rapidly-escalating drug prices found in Jean Holmes, MBA researching pricing and filing a ofBlumberg Medicine Institute in China since and 2015.postdoctoral He received training designed to promote Co-Founder and Senior Advisor: for hepatitis B medications, but we many health plans. The Foundation can complaint, visit www.hepb.org/ disease awareness, and Joan M. Block, RN, BSN need your help to gather data and Special Advisors: overpricing or email [email protected]. support immunization Bob Bowman, PhD document cases to identify areas with Dr. Christoph Seeger at Fox Chase Cancer Chari Cohen, DrPH, MPH and treatment efforts, Gang Chen, MD, PhD where we can be most effective at youalso shopassist for you health in filing. insurance on the Center in Philadelphia. Dr. Guo established his Eddie Cheung, MD Even if you don’t file a complaint, if improving the quality of life for those affected Nadine Shiroma marketplace, take time to thoroughly research laboratory in 2004 in the Department by hepatitis B worldwide. Medical Director – Robert Gish, MD research how much the plan will charge beenof Microbiology working on and the Immunology, molecular pathogenesis Drexel Scientific and Medical Advisory Board medicationchanging policy. are encouraged Patients who to arecontact having for antivirals to protect your rights and andUniversity antiviral College research of Medicine. of hepatitis Dr. viruses,Guo has Harvey Alter, MD difficulty affording their hepatitis B Foundation for 17 years, during which she Timothy Block, PhD your wallet. hasDr. planned, Cohen implementedhas been with and the evaluatedHepatitis B Carol Brosgart, MD Nathaniel Brown, MD past thirty years. community programs and research projects the Foundation at 215-489-4900 or via flaviviruses and human coronaviruses for the Francis Chisari, MD Jean Holmes, focusing on hepatitis B and cancer. Her Raymond Dwek, DPhil, FRS Anthony Ford-Hutchinson, PhD MBA, joined the research focuses on reducing hepatitis B Lawrence Friedman, MD organization as vice related health disparities, including developing Robert Gish, MD Hie-Won Hann, MD Hep B Cure Campaign Grows Momentum president, institutional culturally competent models for improving Stephen Locarnini, MD, PhD advancement, in April health care access. She is co-founder and Anna Lok, MD In 2016, the Hepatitis B Foundation accelerate the pace of discoveries related to William Mason, PhD launched the Hepatitis B Cure Campaign hepatitis B and liver cancer. Brian McMahon, MD Act was introduced by Rep. Nydia Velazquez role, she oversees Edith Mitchell, MD to capitalize on the increased national and Our Roadmap for a Cure provided a (D-NY) to direct the National Cancer development,2018. In her new director of Hep B United Philadelphia, and Robert Perrillo, MD international momentum around hepatitis detailed research agenda for curing hepatitis for liver cancer and to make hospitals and Kenneth Rothstein, MD Institute to create new funding opportunities marketing and events chair of CHIPO: Coalition Against Hepatitis Raymond Schinazi, PhD B, developed by 35 of the world’s leading healthcare facilities eligible to receive new Jean Holmes, MBA for the Hepatitis B for People of African Origin. She sits on the Thomas Shenk, PhD cure. Our goal is to make the elimination funding for experimental treatment and steering committee for NVHR, the National John Tavis, PhD ofB and hepatitis to sharpen B by the2030 focus a national on finding health a hepatitis B and liver cancer convened by prevention programs. The bill also creates Walter Tsou, MD, MPH Viral Hepatitis Roundtable, and served as priority. Since the program was launched thescientists Hepatitis and B clinicians Foundation in the for fieldsthis purpose. of MostFoundation, recently, Baruch she was S. Blumbergat the Bucks Institute, County Association.Policy Chair for the Asian Pacific Islander In Memoriam two years ago, substantial progress has been This research agenda was published in the cancer prevention activities and another for Baruch S. Blumberg, MD, DPhil (2011) two new HHS grant programs: one for liver and the Center. Caucus of the American Public Health HBF Co-Founder and Nobel Laureate made, with several major accomplishments Hepatology awareness activities targeted to Americans Bud Tennant, DVM (2016) that are moving us closer to our goal. in communities at higher risk. HBF Scientific Advisory Board We established a presence in Washington peer-reviewed scientific journal To help the program continue to build W. Thomas London, MD (2017) in 2017. Our Professional Judgment Budget HBF Board of Directors research agenda, aligning them with existing momentum, the Hepatitis B Foundation Please give generously to our 2018 Annual Fund! champions and leadership on Capitol Hill, identified the most critical projects from the has established the Hep B Cure Campaign Managing Editor – Jenny Kimbel conductDC, which advocacy has helped training us to anddevelop meetings new HBV increased investment needed over the next (HBCC) Partnership program to promote Your donation will help us continue our valuable research, outreach, and patient Contact – [email protected] NIH funding mechanisms, and calculating the Copyright 2018 Hepatitis B Foundation increased public-sector investment in Layout & Design: CP Printing Solutions strong appropriations report language hepatitis B and liver cancer research. With cure for hepatitis B and to improve the lives of those affected worldwide. A secure B Informed is a free publication of the with 38 congressional offices, secure investmentsix years to perfollow year the or scientific $526 million roadmap total to increased partnerships and expansion of donationadvocacy canprograms. be made Thank on our you website in advance at www.hepb.org/donate. for your support of our Thank mission you! to find a Hepatitis B Foundation with information that is provided solely for educational purposes. cure hepatitis B. ($232 million additional advocacy efforts to secure research funding, It is not intended to serve as medical advice or from National Institutes of Health (NIH), we believe that the elimination of hepatitis B endorsement of any product or company. Readers should discuss all personal medical questions and Centers for Disease Control (CDC) and over six years) is within our reach. 2 Hepatitis B Foundation | B Informed | Fall 2018 | hepb.org decisions with a qualified health care provider. the Department of Defense (DOD), and In October 2018, the Liver IllnessHepatitis B Foundation | B Informed | Summer 2018 | hepb.org 3 meet with NIH leaders to identify ways to Visibility, Education, and Research (LIVER) HBV Compounds in Development Fall 2018 H V Drug Watch HepB.org/drugwatch Family/Drug Name Mechanism Company Website USA Status Hepatitis B Foundation to Interferons Mimic naturally occurring infection-fighting immune substances produced in the body Intron A (Interferon alfa-2b) Immunomodulator Merck, USA merck.com Approved 1991 Pegasys (PegInterferon alfa-2a) Immunomodulator Genentech, USA gene.com Approved 2005 Provide Resources for Nucleos(t)ide Analogues Interfere with the viral DNA polymerase enzyme used for hepatitis B virus reproduction Epivir (Lamivudine) * Inhibits viral DNA polymerase GlaxoSmithKline (GSK) gsk.com Approved 1998 African Immigrant Hepsera (Adefovir Dipivoxil) * Inhibits viral DNA polymerase Gilead Sciences, USA gilead.com Approved 2002 Baraclude (Entecavir) * Inhibits viral DNA polymerase Bristol-Myers Squibb, USA bms.com Approved 2005 Tyzeka (Telbivudine) * Inhibits viral DNA polymerase Novartis, Switzerland novartis.com Approved 2006 Communities Viread (Tenofovir) Inhibits viral DNA polymerase Gilead Sciences, USA gilead.com Approved 2008 Vemlidy (TAF or Tenofovir Alafenamide) Prodrug of tenofovir Gilead Sciences, USA gilead.com Approved 2016 Levovir (Clevudine) Inhibits viral DNA polymerase Bukwang, S. Korea bukwang.co.kr Approved 2006 in S. Korea he Hepatitis B Foundation, in collaboration Besivo (formerly ANA 380/LB80380) Inhibits viral DNA polymerase Ildong Pharma, S. Korea Ildong.com/en Approved 2017 in S. Korea Twith the CDC Division of Viral Hepatitis, is Zadaxin Immunomodulator SciClone, USA sciclone.com Approved outside USA excited to announce the creation of a collection of DIRECT ACTING ANTIVIRALS Targets the virus and interferes with specific steps in the HBV life cycle to prevent replication TDF Pro Drugs Targets the virus and interferes with specific steps in the HBV life cycle to prevent replication hepatitis B educational resources for African immigrant TXL (CMX 157) Prodrug of tenofovir ContraVir, USA contravir.com Phase II Silencing RNA’s (siRNAs) Interferes and destroys viral RNA ARB-1467 RNAi gene silencer (1.0) Arbutus Biopharma, USA arbutusbio.com Phase II RG6004 RNA gene silencer Roche, Switzerland roche.com Phase I/II Africancommunities immigrants that will and be will released serve inan early unmet 2019. need These to raise creation of culturally-relevant resources. The materials will ARO-HBV RNAi gene silencer Arrowhead Pharmaceuticals, USA arrowheadpharma.com Phase I/II will be the first nationally available resources created for AB-729 RNAi gene silencer Arbutus Biopharma, USA arbutusbio.com Phase I awareness and promote testing for hepatitis B, which is estimated be pilot-tested in multiple communities and will include a ALN-HBV RNAi gene silencer Alnylam and Vir Biotech, USA alnylam.com Preclinical to affect 5-18% of African immigrant communities in the U.S. self-teach audio-visual module for educators, a picture-based BB-103 RNAi gene silencer Benitec, Australia benitec.com Preclinical Lunar-HBV RNAi gene silencer Arcturus, USA with Janssen arcturusrx.com Preclinical Working with an expert advisory board of community health DCR-HBVS RNAi gene silencer Dicerna, USA dicerna.com Preclinical workers, clinicians, scholars and community members, HBF resource toolkit. Future expansion for the project will focus on Entry Inhibitors Interferes with HBV getting into liver cells disseminationflipchart for direct of the community materials, education, media advertising and a comprehensive and community Myrcludex B Entry inhibitor Hepatera, Russia with MYR GmbH, myr-pharma.com Phase II conducted an assessment of current hepatitis B knowledge, Capsid Inhibitors Interferes with the viral DNA protein shield barriers to accessing testing and care, and strategies to address outreach. Subscribe to our e-newsletter for news and updates Morphothiadin (GLS4) Capsid inhibitor HEC Pharma, PR China pharm.hec.cn/en Phase II on these materials! JNJ56136379 Capsid inhibitor Janssen, Scotland janssen.com Phase II current gaps. The data we collected was used to inform the ABI-H0731 Capsid inhibitor Assembly Biosciences, USA assemblybio.com Phase II AB-423 Capsid inhibitor Arbutus Biopharma, USA arbutusbio.com Phase I AB-506 Capsid inhibitor Arbutus Biopharma, USA arbutusbio.com Phase I ABI-H2158 Capsid inhibitor Assembly Biosciences assemblybio.com Phase I RG7907 Capsid inhibitor Roche, Switzerland roche.com Phase I QL-007 Capsid inhibitor Qilu Pharmaceuticals, China qilu-pharma.com Phase I GLP-26 Capsid inhibitor Emory University, USA emory.edu Preclinical Focus on EP-027367 Capsid inhibitor Enanta Pharmaceuticals, USA enanta.com Preclinical QL-0A6a Capsid inhibitor Qilu Pharmaceuticals, China qilu-pharma.com Preclinical Hepatitis Delta HBsAg Inhibitors Interferes with production of HBV surface antigen (sAg) Rep 2139 sAg inhibitor REPLICor, Canada replicor.com Phase II Rep 2165 sAg inhibitor REPLICor, Canada replicor.com Phase II Antisense Molecules Binds to the viral mRNA to prevent it from turning into viral protein IONIS-HBVRx (GSK3228836) Viral protein inhibitor Ionis Pharma with GSK, USA ionispharma.com Phase II IONIS-HBVLRx (GSK33389404) Viral protein inhibitor Ionis Pharma with GSK, USA ionispharma.com Phase II Karen and Dave: Ribonuclease H Inhibitor Inhibit degradation of viral RNA One Couple’s Journey through Hepatitis B, Hepatitis D, ARB-452 Viral RNase inhibitor Arbutus Biopharma, Canada arbutusbio.com Preclinical INDIRECT ACTING ANTIVIRALS Targets the human immune system to attack the HBV virus Liver Cancer and a Successful Transplant Therapeutic Vaccines Vaccine technology used to stimulate the immune system as a treatment AIC 649 Therapeutic vaccine AiCuris, Germany aicuris.com Phase I Due to changes in our health insurance, we were sent to a INO-1800 Therapeutic vaccine Inovio, USA inovio.com Phase I HB-110 Therapeutic vaccine Ichor Medical Systems, USA ichorms.com Phase I highly respected liver center in California, who helped save Dave’s TG1050 Therapeutic vaccine Transgene, France transgene.com Phase I ave knew he had hepatitis B for decades, but life. He now had liver cancer and was taking interferon treatment HepTcell Therapeutic vaccine Altimmune, USA altimmune.com Phase I HBV (TomegaVax) Therapeutic vaccine Vir Biotechnology, USA vir.bio Preclinical “Dhonestly, no one ever seemed concerned – for his hepatitis D. Still, he was doing poorly and although he HBV Therapeutic vaccine GeoVax Labs, USA geovax.com Preclinical doctors hadn’t even insisted on yearly blood tests! In 2016, a was on the transplant list, didn’t qualify for an organ yet. After VR-CHB01 Therapeutic Vaccine Vical, USA vical.com Preclinical Innate Immune Defense Pathway Compounds that activate the innate immune system routine colonoscopy and subsequent blood testing revealed many months, hundreds of office and emergency room visits, RG7795 TLR-7 agonist Roche, Switzerland roche.com Phase II Dave had serious liver disease. We were blindsided. he qualified, and we got the call – on Thanksgiving night 2017! Inarigivir (SB9200) RIG -1 and NOD2 agonist Spring Bank Pharmaceuticals, USA springbankpharm.com Phase II GS9688 TLR-8 agonist Gilead Sciences, USA gilead.com Phase I In the beginning, we faced insensitive and ignorant doctors There was a healthy liver available, and we took it. RG7854 TLR-7 agonist Roche, Switzerland roche.com Phase I who told Dave there was nothing they could do. They even As a caregiver, it was tough. No one prepares you for the Host Acting Pathway Compounds that induce programmed cell death (apoptosis) physical and mental toll it takes to support someone who is APG-1387 Apoptosis Inducer Ascentage Pharma, China en.ascentagepharma.com Phase I refused him treatment for his hepatitis B and never referred him CRV 431 (CPI 431-32) Ciclofillin inhibitor ContraVir, USA contravir.com Preclinical to a transplant clinic. During this time, Dave’s liver was getting in pain, incapacitated, and often, down-right nasty. It was an Viral Gene Editing worse and we couldn’t afford to waste any more time. Eventually, enormous stress on me; driving, paying bills, our construction EBT106 CRISPR/Cas 9 Excision Biotherapeutics, USA excisionbio.com Preclinical HBV CRISPR/Cas 9 Intellia Therapeutics, USA intelliatx.com Preclinical he found a knowledgeable doctor who put him on antivirals business: you name it, I did it all. HBV CRISPR/Cas 9 Precision Pharma with Gilead, USA precisionsciences.com Preclinical and knew to test him for hepatitis D, a dangerous coinfection of But the good we took away is his health! Dave still doesn’t Other GC1102 sAg monoclonal antibody Green Cross, S. Korea globalgreencross.com Phase II hepatitis B. “It won’t be good if you have it,” he said. feel it was real. We went through so much and are so grateful to EYP001 FXR agonist Enyo Pharma, France enyopharma.com Phase I He did. be on the other side.” LTCR-H2-1 T cell immunotherapy Lion TCR, Singapore Liontcr.com Preclinical IMMTav T cell immunomodulator Immunocore, USA immunocore.com Preclinical Karen HBV MicroRNA Regulus Therapeutics, USA regulusrx.com Preclinical Hepatitis Delta Virus (HDV) Lambda (Pegylated Interferon Immune response stimulator Eiger Biopharma, USA eigerbio.com Orphan Drug Status Phase II Hepatitis Delta Connect is a dedicated program of the Hepatitis B Foundation to increase awareness about Myrcludex B Entry inhibitor MYR-GmbH, Germany myr-pharma.com Phase II this serious virus that co-infects hepatitis B patients, promote screening and testing, and provide information Lonafarnib Prenylation inhibitor Eiger Biopharma, USA eigerbio.com FDA Fast Track / Orphan Drug Designation Phase II and support for those affected. If you are a hepatitis D patient or provider and have questions, please visit our REP 2139 / REP 2165 HBsAg inhibitor REPLICor, Canada replicor.com Phase II Hepatitis Delta Connect website at www.hepdconnect.org, or email us at: [email protected]. Ezetimibe NTCP inhibitor Ziauddin University Hospital, Pakistan zu.edu.pk Phase II Aln-hDV RNAi gene silencer Alnylam, USA alnylam.com Preclinical GI-18000 Immune Response Stimulator GlobeImmune, USA globeimmune.com Preclinical 4 Hepatitis B Foundation | B Informed | Fall 2018 | hepb.org * Generics Available Hepatitis B Foundation | B Informed | Fall 2018 | hepb.org 5 Sixth Annual Hep B United Summit Focuses Provider Profile on Achieving Health Equity

he 6th Annual Hep B United Su Wang, MD, MPH T Medical Director, Center for Asian Health Saint Barnabas Medical Center 26, 2018National – just Summit a few days was beforeheld Board Member, Hepatitis B Foundation in Washington, D.C. on July 24- Approximately 80 people from 50World organizations, Hepatitis Day campaigns, on July 28. and coalitions from around the United When Dr. Su Wang moved to from learn more about the current state New York City, she noticed something unusual ofStates hepatitis joined B Hepand Bto United advocate (HBU) for to about the way local patients sought care. increased support and prioritization from the federal government. The Summit provides came to her. federal, state, and community- The 2018 Hep B United Summit attracted over 80 attendees “A “Treating hepatitis B was not something based organizations with the from 50 organizations to the event in Washington, DC. was a veryfter strong living Asian[in northern community New here,Jersey] highest“New Asian Jersey population just hadn’t in been the US,” tapped she says.into opportunity to join forces and but people for were three not years, accessing I noticed health that care there as much and yet it is so diverse. It’s the fourth one of the pioneers to start training [primary share their expertise and knowledge. Health and Human Services’ commitment to to do some screenings. We’re really trying to I learned during residency, but CBWCHC was The collaborative work that is done at hours! Advocates shared their personal eliminating hepatitis B. Senator Hirono was Flushing, into Chinatown to see a doctor once do“My prevention passion was and hepatitis true population B, so I got health, grants important training for doctors who treat a the Summit provides momentum for the experiencesCongressional with offices hepatitis in just B underand asked four alocally. year, butThey then would they go wouldn’t into New have York, anybody into which means not just treating people who populationcare] doctors of topeople treat withhep B.high It is prevalence,” especially hepatitis B community and allows for the their representatives to support funding B Congressional Champion Award for her nearby to see. Some of it was the language are sick, but really trying to keep people from growth of new ideas and plans of action on for expanded hepatitis B surveillance and dedicationpresented withto elevating the first hepatitis annual Hepatitis B research barrier, the cultural barrier. When it comes respond to a need in their own community. both a community and organizational level. prevention programs, funding towards at a national level; Arman Altug from the to medical stuff, they still prefer to speak to Sometimesshe continued. seeing “It’s a aspecialist way for ais physician a barrier, to Each annual Summit advances our movement Charles somebody in their own language. And that is “Becausegetting sick. for That’s hep B, where the screening I think the and public early and primary care doctors who see high risk hepatitis B and improving treatment B. Wang Community Health Center, and enough of a barrier where they just won’t go.” treatmenthealth thing all that helps I do keep is helpful,” people healthy.”she says. patients should be able to offer care.” recent successes, and move the community options,accelerating and researchimproved to resources find a cure to forincrease KensonHepatitis and Education Rensely Project, Alik from the Hep Free to effectively address hepatitis B, reflect on one step closer to eliminating hepatitis B. vaccination rates among adults. Hawaii and the #justB storytelling campaign She approached the Saint Barnabas Health during her medical training at University Su Wang, MD, MPH is the Medical The 2018 summit theme was Achieving On Wednesday, July 25, Senator Mazie were also recognized for the work that SystemDr. Wang’s with her vision idea. was “They to fillhad that great void. of Miami.Dr. Wang’s After interest her residency, in public she health did a begantwo Director for the Center for Asian Health at Health Equity to End Hepatitis B, with Hirono from Hawaii, and Representatives they’ve done to address hepatitis B in their year public health fellowship with Centers Saint Barnabas Medical Center in Florham sessions that addressed expanding hepatitis Judy Chu from California’s 27th district, communities. between those services and the community,” Park, NJ. She is committed to Asian B screenings in high-risk communities, Hank Johnson from Georgia’s 4th district, Established by the Hepatitis B Foundation sheservices, says. andThey I wantedagreed, andto be in the 2013, bridge the for a clinical position. That search landed health and wellness, as well as the clinical combating stigma and discrimination, and Brian Fitzpatrick Center for Asian Health at Saint Barnabas herfor Disease a job at Control,the Charles then B beganWang Communitysearching identification and treatment of hepatitis B. She currently serves as the Executive disparities in hepatitis B medication pricing, 8th district joined a Congressional reception more than 30 local coalitions across 26 cities Board Member for the Americas Region for and preventing perinatal transmission. hosted by the Hepatitis fromB Foundation Pennsylvania’s to and AAPCHO in 2012, Hep B United now has The Center’s patient population had a high Medical Center in Florham Park was born. Health Center in New York City (CBWCHC). the World Hepatitis Alliance. She joined the The day before the Summit began, recognize community and Congressional all with the goal of promoting screening, Mandarin, also recruited other bilingual Board of the Hepatitis B Foundation in 2017. attendees participated in a hepatitis B Hep B Champions. Dr. Matthew Lin vaccinationin 19 states and linkagethe District to care of Columbia, to eliminate physiciansDr. Wang, who to join is fluent her practice. in both English and quickly learned how to treat the patients who advocacy day on Capitol Hill. More than Assistant Secretary for Minority Health, hepatitis B. prevalence of hepatitis B, and Dr. Wang 65 participants were able to meet with 61 , Deputy

shared remarks on the Department of n YES! I want to support the Hepatitis B Foundation with a tax-deductible gift. Name______he Hepatitis B Foundation recorded six These stories were created to provide information Address______Tnew stories this summer for our #justB and raise awareness about hepatitis B issues in the New Videos campaign, for a total of 30 unique stories and globally. We invite others to use the City______State______Zip______Email______Your gift gives hope and Updated available as part of our national, multilingual videos as a tool to educate audiences about screening Donation Amount: n $25 n $50 n $100 n Other $______hepatitis B storytelling campaign. Their and prevention, and advocate for increased attention to millions affected Please charge my gift to my credit card: n Mastercard n Visa n American Express n Discover Discussion stories include messages of hope and encouragement to the virus within the health professions and broader by hepatitis B. Name on Card______Exp Date______Guide despite difficult situations such as facing discrimination medical community. To help facilitate discussion, a due to having chronic hepatitis B, recovering from an newly updated Discussion Guide is available to prepare Make a secure donation Card #______Security Code*______Now Available *We cannot process your donation emergency liver transplant surgery, learning to take presenters to lead conversations about online at www.hepb.org Signature______without the security code. control of one’s health after being diagnosed and losing the experiences presented in the videos. Please make check payable to: Hepatitis B Foundation a family member to the disease, or working with limited To view the new videos and download Use remittance envelope or mail to: 3805 Old Easton Road, Doylestown, PA 18902 USA resources to fill the gaps in hepatitis B education and the newly updated Discussion Guide, Donations will be acknowledged in our Annual Report unless otherwise requested. access to care for your community. visit www.hepb.org/justb. A copy of the official registration and financial information may be obtained by calling the PA Department of State toll-free within PA at 800-732-0999 or out-of-state at 717-783-1720. Registration does not imply endorsement.

6 Hepatitis B Foundation | B Informed | Fall 2018 | hepb.org Hepatitis B Foundation | B Informed | Fall 2018 | hepb.org 7 Nonprofit Org u.s. postage paid Permit No 38 Doylestown, PA 3805 Easton Road Doylestown, PA 18902 Phone: (215) 489-4900 www.hepb.org [email protected]

Hepatitis B Foundation Boards Add Two New Members

he Hepatitis B Foundation is Tpleased to announce the addition of David A. Gruber, CPA to its Board Anna Lok, MD to its

of Directors, and Scientificaccountant and with Medical over 40 Advisory years of Board. Mr. Gruber is a certified public

andexperience consulting in nonprofit services throughaccounting. his He Calendar of Events company,currently providesGruber Administrative financial, business, Services, and serves as trustee for several family trusts. He is a member 2019 April 26 2019 Crystal Ball Gala Feb 20-24 Hepatitis B Foundation Accountantsof both the American and is active and onPennsylvania several APASL 2019 Blue Bell, PA, USA Institutes of Certified Public Asian Pacific Association for the Study hepb.org of the Liver nonprofit boards. He joined the HBF Manila, Philippines May 19 apasl2019manila.org National Hepatitis Testing Day Board of Directors in August. renowned hepatologist with a more United States CDC Dr. Lok is an internationally than 30 year career focused on the March 8-9 Events around the country natural history and treatment of EASL-AASLD HBV Endpoints Meeting cdc.gov/hepatitis/testingday hepatitis B and C. She is the Alice European Association for the Study of the Liver and American Association for July 28 the Study of Liver Diseases World Hepatitis Day Lohrman Andrews Research Professor London, UK WHO and WHA Events around the world Michiganin Hepatology Health at System.the Department Her research of easl.eu Internal Medicine at the University of worldhepatitisday.org has been supported by federal April 10-14 International Liver Congress October 1-4 European Association for the Study of 2019 International HBV Meeting grants from the Veterans Health the Liver Hepatitis B Foundation moreAdministration than 350 articles,and the reviews,National Vienna, Austria Melbourne, Australia editorials,Institutes ofand Health. book Shechapters. has published easl.eu HBVmeeting.org

For More Information About Find HBF on social media networks… Hepatitis B Foundation Programs /hepbfoundation @hepbfoundation @hepbfoundation ● HB V Info & Support List … HBList.net ● HB V Clinical Trials … hepb.org/clinicaltrials /hepbfoundation hepb.org/blog @hepbfoundation ● HB V Drug Watch … hepb.org/drugwatch ●  B Informed and all back issues are available online at Hepatitis Delta Connect … hepDconnect.org www.hepb.org/newsletters ● Liver Cancer Connect … livercancerconnect.org

8 Hepatitis B Foundation | B Informed | Fall 2018 | hepb.org