September 29 & 30, 2020
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
International Symposium of Human Genetics
ichg2022.com THE INTERNATIONAL The 14th International Congress of Human FEDERATION OF HUMAN Genetics was postponed GENETICS SOCIETIES by almost a year due to the COVID-19 pandemic, PRESENTS: and the LOC has decided to host a Symposium in 2021 as a taster of what will be expected at the International Congress in 2022. We are bringing together Symposium on exceptional speakers for two sessions on topics that are highly relevant to Human Genetics human geneticists and these discussions will be picked up again at the 9 & 10 March 2021 main meeting in 2022. DAY 1: The shaping of modern Tue 9 March 2021 3pm - 5pm human genomes: migration, admixture & Wed 10 March 2021 9am - 11 am ancient genomic Times are listed in SAST introgression DAY 2: Infectious diseases and Virtual Conference Platform our genome Programme: T U E S D A Y , 9 M A R C H 2 0 2 1 1 5 : 0 0 - 1 7 : 0 0 S A S T ( G M T + 2 ) The shaping of modern human genomes: migration, admixture and ancient genomic introgression - Chaired by Charles Rotimi & Michele Ramsay Since the emergence of modern man in Africa between 400,000 and 600,000 years ago, evolutionary forces have been shaping the human genome. Studies on the genomes of people living today and some who died thousands of years ago provide clues to our past and we begin to unravel a story of migration, admixture and adaptation. In this session we start with African population genomics, then adaptive signatures and introgression form extinct hominids to the peopling of Asia. -
CV Than, NA Rosenberg
Noah A. Rosenberg Department of Biology Stanford University Stanford, CA 94305-5020 USA (650) 721-2599 (phone) (650) 724-5114 (fax) [email protected] http://rosenberglab.stanford.edu/ August 9, 2017 Academic appointments 2014- Stanford Professor of Population Genetics and Society, Stanford University School of Humanities and Sciences 2014- Professor, Stanford University Department of Biology 2011-2014 Associate Professor, Stanford University Department of Biology 2009-2011 Associate Professor, University of Michigan Depts. of Human Genetics, Ecology & Evolutionary Biology, and Biostatistics Research Associate Professor, University of Michigan Life Sciences Institute and Center for Computational Medicine & Bioinformatics 2005-2009 Assistant Professor, University of Michigan Depts. of Human Genetics, Ecology & Evolutionary Biology (2006-2009), and Biostatistics Research Assistant Professor, University of Michigan Life Sciences Institute and Center for Computational Medicine & Bioinformatics Education 2001-2005 Postdoc, University of Southern California, Molecular and Computational Biology 1998-2001 PhD, Stanford University, Biological Sciences 1997-1999 MS, Stanford University, Mathematics 1993-1997 BA, Rice University, Mathematics and Russian Studies, summa cum laude Awards Fellowships 2007 Faculty Research Grant, University of Michigan Rackham Graduate School 2006 Faculty Fellowship Enhancement Award, University of Michigan Rackham Graduate School 2006-2010 Alfred P. Sloan Research Fellowship in Computational and Evolutionary Molecular -
Malaria Journal Biomed Central
Malaria Journal BioMed Central Review Open Access Sex separation strategies: past experience and new approaches Philippos A Papathanos1, Hervé C Bossin2, Mark Q Benedict3, Flaminia Catteruccia1, Colin A Malcolm4, Luke Alphey5,6 and Andrea Crisanti*1 Address: 1Imperial College London, Department of Biological Sciences, Imperial College Road, London SW7 2AZ, UK, 2Medical Entomology Laboratory, Institut Louis Malardé, BP 30, 98713 Papeete, Tahiti - French Polynesia, 3Entomology Unit, FAO/IAEA Agriculture and Biotechnology Laboratory, IAEA Laboratories, A-2444 Seibersdorf, Austria, 4School of Biological Sciences, Queen Mary, University of London, Mile End Road, London, E1 4NS, UK, 5Oxitec Ltd, Milton Park, Abingdon, Oxford OX14 4RX, UK and 6Dept. of Zoology, University of Oxford, South Parks Road, Oxford OX1 2PS, UK Email: Philippos A Papathanos - [email protected]; Hervé C Bossin - [email protected]; Mark Q Benedict - [email protected]; Flaminia Catteruccia - [email protected]; Colin A Malcolm - [email protected]; Luke Alphey - [email protected]; Andrea Crisanti* - [email protected] * Corresponding author Published: 16 November 2009 <supplement>and Tropical Medicine. <title> <p>Development His scientific efforts of theto control sterile insectvector-borne technique diseases for African continually malaria focused vectors</p> on maximizing </title> <editor>Markhumanitarian o Qutcomes.</note> Benedict, Alan S </sponsor> Robinson and <note>Reviews</note> Bart GJ Knols</editor> </supplement> <sponsor> <note>This supplement is dedicated to Prof. Chris Curtis (1939-2008) of the London School of Hygiene Malaria Journal 2009, 8(Suppl 2):S5 doi:10.1186/1475-2875-8-S2-S5 This article is available from: http://www.malariajournal.com/content/8/S2/S5 © 2009 Papathanos et al; licensee BioMed Central Ltd. -
Angela N. Koehler
Angela N. Koehler Broad Institute of MIT and Harvard Office: 617-714-7364 Chemical Biology Program Fax: 617-714-8943 7 Cambridge Center Email: [email protected] Cambridge, MA 02142 Website: www.broadinstitute.org/node/2445 Education Ph.D. Chemistry, Harvard University, 2003 B.A. Biochemistry and Molecular Biology, Reed College, 1997 Research Experience Investigator, Chemical Biology Program, Broad Institute 2009-present Project & Center Manager, Broad NCI Cancer Target Discovery and Development (CTD2) Center 2010-2012 Institute Fellow, Chemical Biology Program, Broad Institute 2003-2009 Director, Ligand Discovery, NCI Initiative for Chemical Genetics (ICG) at Harvard 2003-2009 Graduate Student, Department of Chemistry and Chemical Biology, Harvard University 1998-2003 Laboratory of Professor Stuart L. Schreiber Thesis: Small molecule microarrays: A high-throughput tool for discovering protein-small molecule interactions Researcher, Department of Chemistry, California Institute of Technology 1997-1998 Laboratory of Professor Barbara Imperiali Project: Biochemical reconstitution of the oligosaccharyltransferase (OST) complex Undergraduate Researcher, Department of Chemistry, Reed College 1995-1997 Laboratory of Professor Arthur Glasfeld Co-mentored by Professor Richard G. Brennan at Oregon Health Sciences University Thesis: Biochemical and structural characterization of the tRNA-modifying enzyme QueA from Escherichia coli Teaching Experience Research Advisor to postdoctoral fellows, undergraduates, high school students, and staff scientists 2003-present Broad Institute of MIT and Harvard Instructor, Biochemical Sciences Research (BS91r) 2004-2006, 2010-2011 Harvard University Associated Instructor, Experimental Research in the Life Sciences (LS100r) 2009 Harvard University Associated Instructor, Experimental Molecular and Cellular Biology (MCB100) 2004-2006 Harvard University Teaching Fellow, Chemical Biology (Chem 170) 1999, 2000 Harvard University, Professor David R. -
CRISPR-Based Innovative Genetic Tools for Control of Anopheles Gambiae Mosquitoes
CRISPR-based innovative genetic tools for control of Anopheles gambiae mosquitoes The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Smidler, Andrea. 2019. CRISPR-based innovative genetic tools for control of Anopheles gambiae mosquitoes. Doctoral dissertation, Harvard University, Graduate School of Arts & Sciences. Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:42029729 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of- use#LAA CRISPR-based innovative genetic tools for control of Anopheles gambiae mosquitoes A dissertation presented by Andrea L. Smidler to The Committee on Higher Degrees in Biological Sciences in Public Health in partial fulfillment of the requirements for the degree of Doctor of Philosophy In the subject of Biological Sciences in Public Health Harvard University Cambridge, Massachusetts April 2019 i © 2019 – Andrea Smidler All rights reserved ii Dissertation Advisor: Dr. Flaminia Catteruccia, Dr. George Church Andrea Smidler CRISPR-based innovative genetic tools for control of Anopheles gambiae mosquitoes ABSTRACT Malaria and other mosquito-borne diseases pose an immense burden on mankind. Since the turn of the century, control campaigns have relied on the use of insecticide-impregnated bed nets and indoor residual sprays to stop Anopheles mosquitoes from transmitting the malaria parasite. Although these are our best strategies to control the spread of disease, wild mosquito populations are developing resistance to insecticides at an alarming rate, making disease control increasingly challenging. -
Prediction of Mosquito Species and Population Age Structure Using Mid-Infrared Spectroscopy and Supervised Machine Learning
JANUARY 2020 Contents Selected Recent Publications ...................................................................................................................................................... 1 Prediction of mosquito species and population age structure using mid-infrared spectroscopy and supervised machine learning .................................................................................................................................................................................... 1 Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges. ................... 1 Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand ................................................................................................ 2 Efficacy of a spatial repellent for control of malaria in Indonesia: a cluster-randomized controlled trial ............................. 2 Cross-resistance profiles of malaria mosquito P450s associated with pyrethroid resistance against WHO insecticides ...... 2 Characterisation of Anopheles strains used for laboratory screening of new vector control ................................................ 3 Bacteria-mediated modification of insecticide toxicity in the yellow fever mosquito, Aedes aegypti ................................... 3 Open source 3D printable replacement parts for the WHO insecticide susceptibility bioassay system ............................... -
2021 the Packard Fellowships for Science and Engineering
The Packard Fellowships for Science and Engineering 2021 Guidelines The Packard Fellowships for Science and Engineering $175,000 paid each year, $17,500 is available to the program invests in future leaders who have the university as compensation for administrative costs. freedom to take risks, explore new frontiers in their fields of study, and follow uncharted paths that may Over the past 32 years, the Foundation has awarded lead to groundbreaking discoveries. $447 million to support over 630 scientists and engineers from 54 top national universities. It is Program Overview among the nation's largest nongovernmental fellowships, designed to allow maximum flexibility on The success of the Hewlett-Packard Company was how the funding is used. Packard Fellows have gone built on technology, derived in large measure from on to receive many additional awards and honors, research and development in university laboratories. including Nobel Prizes in Chemistry and Physics, Fields Because the endowment of the David and Lucile Medals, Alan T. Waterman Awards, Breakthrough Packard Foundation would not have been possible Prizes and elections to the National Academy of without the success of HP and because the research Science, Engineering and Medicine. performed by university-educated engineers and scientists will provide the basis for future high-value What We Fund economic activity for the nation, the Foundation has a long-standing interest in strengthening both Candidates must be faculty members who are eligible university-based research and graduate education. to serve as principal investigators engaged in research in the natural and physical sciences or engineering In 1988, the Foundation established the Packard and must be within the first three years of their Fellowships for Science and Engineering to allow the faculty careers. -
20131114 D44001 Mosquito RCM1 Report
FIRST RESEARCH CO-ORDINATION MEETING Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture Co-ordinated Research Programme on Explore mechanical, molecular, behavioural or genetic methods of sex separation in mosquitoes Scientific Secretary: Jeremie Gilles & Kostas Bourtzis IAEA Headquarters Vienna, Austria 30 September -4 October 2013 1 Contents PROPOSAL FOR A COORDINATED RESEARCH PROJECT (CRP) ................................ 3 Title .................................................................................................................................. 3 Budget Cycle..................................................................................................................... 3 Project ............................................................................................................................... 3 Division ............................................................................................................................ 3 Responsible Project Officer ............................................................................................... 3 Alternate Project Officer ................................................................................................... 3 Summary ........................................................................................................................... 3 Background Situation Analysis: ........................................................................................ 4 To explore irradiation and classical genetic approaches -
Dysregulated Hematopoiesis Caused by Mammary Cancer Is Associated with Epigenetic Changes and Hox Gene Expression in Hematopoietic Cells Alexander Sio1*, Manreet K
Author Manuscript Published OnlineFirst on August 1, 2013; DOI: 10.1158/0008-5472.CAN-13-0842 Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Dysregulated hematopoiesis caused by mammary cancer is associated with epigenetic changes and Hox gene expression in hematopoietic cells Alexander Sio1*, Manreet K. Chehal1*, Kevin Tsai1, Xueling Fan1, Morgan E. Roberts1, Brad H. Nelson2, Jolanta Grembecka3, Tomasz Cierpicki3, Danielle L. Krebs1 and Kenneth W. Harder1 1Department of Microbiology and Immunology, I3 Research Group, Life Sciences Institute, University of British Columbia, Vancouver, B.C., Canada. 2Trev and Joyce Deeley Research Centre, British Columbia Cancer Agency, Victoria, B.C., Canada. 3Department of Pathology, University of Michigan, Ann Arbor, MI., USA. *Authors contributed equally to this work. Running Title: MAMMARY CANCER INDUCES DEFECTS IN HEMATOPOIESIS Keywords: hematopoiesis, mammary tumors, HOXA9, G-CSF, epigenetics Supported by grants from the Canadian Breast Cancer Foundation (KWH, DLK) and Canadian Institutes of Health Research (CIHR, KWH, CIHRMOP-86694). KWH holds a Tier-II Canada Research Chair. Studentships to MKC (Michael Smith Foundation and CIHR), MER (CIHR Training Program in Transplantation), and XF (University of British Columbia/4YF) helped support these studies. Correspondence: Kenneth W. Harder, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, B.C., V6T-1Z3; e-mail: [email protected] Word Count: Total number of figures and tables: 7 Conflict-of-interest disclosure: The authors declare no competing financial interests. 1 Downloaded from cancerres.aacrjournals.org on October 1, 2021. © 2013 American Association for Cancer Research. Author Manuscript Published OnlineFirst on August 1, 2013; DOI: 10.1158/0008-5472.CAN-13-0842 Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. -
The Road Ahead in Genetics and Genomics
VIEWPOINT against police brutality towards African American citizens4 have strengthened The road ahead in genetics and the antiracism movement and amplified demands for racial equity. genomics To be part of this movement and effect change will require humility. We must actively listen and learn from each other, Amy L. McGuire, Stacey Gabriel, Sarah A. Tishkoff , Ambroise Wonkam , especially when it is uncomfortable and our Aravinda Chakravarti , Eileen E. M. Furlong , Barbara Treutlein , own complicity may be implicated. It will Alexander Meissner , Howard Y. Chang , Núria López- Bigas , Eran Segal require solidarity and a recognition that and Jin- Soo Kim we are all connected through our common humanity. And it will require courage. It Abstract | In celebration of the 20th anniversary of Nature Reviews Genetics, we may seem like a platitude, but it is true that asked 12 leading researchers to reflect on the key challenges and opportunities nothing will change unless actual change is faced by the field of genetics and genomics. Keeping their particular research area made. If we continue to do things as they in mind, they take stock of the current state of play and emphasize the work that have always been done, we will end up where remains to be done over the next few years so that, ultimately, the benefits of we have always been. It is time to step into the discomfort and dare to do something genetic and genomic research can be felt by everyone. different. So what can we do differently to make Making genomics truly equitable These advancements raise many ethical genomics more equitable? I propose three Amy McGuire. -
Angela N. Koehler
Angela N. Koehler Koch Institute for Integrative Cancer Research at MIT Office: 617-324-7631 Department of Biological Engineering, MIT Email: [email protected] 76-361C Website: http://koehler-lab.mit.edu/ 77 Massachusetts Avenue Cambridge, MA 02139 Education Ph.D. Chemistry, Harvard University 2003 B.A. Biochemistry and Molecular Biology, Reed College 1997 Professional Appointments Associate Professor, Department of Biological Engineering, MIT 2019-present Institute Member, Broad Institute of MIT and Harvard 2019-present Founding Member, MIT Center for Precision Cancer Medicine 2018-present Goldblith Career Development Professor in Applied Biology 2018-2021 Intramural Faculty, Koch Institute for Integrative Cancer Research at MIT 2014-present Assistant Professor, Department of Biological Engineering, MIT 2014-2018 Karl Van Tassel (1925) Career Development Professor 2014-2017 Director, Transcriptional Chemical Biology, Chemical Biology Program, Broad Institute 2010-2013 Project & Center Manager, Broad NCI Cancer Target Discovery and Development (CTD2) Center Institute Fellow, Chemical Biology Program, Broad Institute 2003-2009 Director, Ligand Discovery, NCI Initiative for Chemical Genetics (ICG) at Harvard Research Training Graduate Student, Department of Chemistry and Chemical Biology, Harvard University 1998-2003 Laboratory of Professor Stuart L. Schreiber Committee: Professors Eric. N. Jacobsen, David R. Liu Thesis: Small molecule microarrays: A high-throughput tool for discovering protein-small molecule interactions Researcher, Department -
High-Throughput Sorting of Mosquito Larvae for Laboratory Studies and for Future Vector Control Interventions
High-throughput sorting of mosquito larvae for laboratory studies and for future vector control interventions. Eric Marois, Christina Scali, Julien Soichot, Christine Kappler, Elena Levashina, Flaminia Catteruccia To cite this version: Eric Marois, Christina Scali, Julien Soichot, Christine Kappler, Elena Levashina, et al.. High- throughput sorting of mosquito larvae for laboratory studies and for future vector control interven- tions.. Malaria Journal, BioMed Central, 2012, 11 (1), pp.302. 10.1186/1475-2875-11-302. inserm- 00741472 HAL Id: inserm-00741472 https://www.hal.inserm.fr/inserm-00741472 Submitted on 12 Oct 2012 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Marois et al. Malaria Journal 2012, 11:302 http://www.malariajournal.com/content/11/1/302 METHODOLOGY Open Access High-throughput sorting of mosquito larvae for laboratory studies and for future vector control interventions Eric Marois1, Christina Scali2, Julien Soichot1, Christine Kappler1, Elena A Levashina1,3*† and Flaminia Catteruccia4,5*† Abstract Background: Mosquito transgenesis offers new promises for the genetic control of vector-borne infectious diseases such as malaria and dengue fever. Genetic control strategies require the release of large number of male mosquitoes into field populations, whether they are based on the use of sterile males (sterile insect technique, SIT) or on introducing genetic traits conferring refractoriness to disease transmission (population replacement).