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Human Physiology an Integrated Approach
Gas Exchange and Transport Gas Exchange in the Lungs and Tissues 18 Lower Alveolar P Decreases Oxygen Uptake O2 Diff usion Problems Cause Hypoxia Gas Solubility Aff ects Diff usion Gas Transport in the Blood Hemoglobin Binds to Oxygen Oxygen Binding Obeys the Law of Mass Action Hemoglobin Transports Most Oxygen to the Tissues P Determines Oxygen-Hb Binding O2 Oxygen Binding Is Expressed As a Percentage Several Factors Aff ect Oxygen-Hb Binding Carbon Dioxide Is Transported in Three Ways Regulation of Ventilation Neurons in the Medulla Control Breathing Carbon Dioxide, Oxygen, and pH Infl uence Ventilation Protective Refl exes Guard the Lungs Higher Brain Centers Aff ect Patterns of Ventilation The successful ascent of Everest without supplementary oxygen is one of the great sagas of the 20th century. — John B. West, Climbing with O’s , NOVA Online (www.pbs.org) Background Basics Exchange epithelia pH and buff ers Law of mass action Cerebrospinal fl uid Simple diff usion Autonomic and somatic motor neurons Structure of the brain stem Red blood cells and Giant liposomes hemoglobin of pulmonary Blood-brain barrier surfactant (40X) From Chapter 18 of Human Physiology: An Integrated Approach, Sixth Edition. Dee Unglaub Silverthorn. Copyright © 2013 by Pearson Education, Inc. All rights reserved. 633 Gas Exchange and Transport he book Into Thin Air by Jon Krakauer chronicles an ill- RUNNING PROBLEM fated trek to the top of Mt. Everest. To reach the summit of Mt. Everest, climbers must pass through the “death zone” T High Altitude located at about 8000 meters (over 26,000 ft ). Of the thousands of people who have attempted the summit, only about 2000 have been In 1981 a group of 20 physiologists, physicians, and successful, and more than 185 have died. -
Everest and Oxygen—Ruminations by a Climber Anesthesiologist by David Larson, M.D
Everest and Oxygen—Ruminations by a Climber Anesthesiologist By David Larson, M.D. Gaining Altitude and Losing Partial Pressure with Dave and Samantha Larson Dr. Dave Larson is an obstetric anesthesiologist who practices at Long Beach Memorial Medical Center, and his daughter Samantha is a freshman at Stanford University. Together they have successfully ascended the Seven Summits, the tallest peaks on each of the seven continents, a feat of mountaineering postulated in the 1980s by Richard Bass, owner of the Snowbird Ski Resort in Utah. Bass accomplished it first in 1985. Samantha Larson, who scaled Everest in May 2007 (the youngest non-Sherpa to do so) and the Carstensz Pyramid in August 2007, is at age 18 the youngest ever to have achieved this feat. Because of varying definitions of continental borders based upon geography, geology, and geopolitics, there are nine potential summits, but the Seven Summits is based upon the American and Western European model. Reinhold Messner, an Italian mountaineer known for ascending without supplemental oxygen, postulated a list of Seven Summits that replaced a mountain on the Australian mainland (Mount Kosciuszko—2,228 m) with a higher peak in Oceania on New Guinea (the Carstensz Pyramid—4,884 m). The other variation in defining summits is whether you define Mount Blanc (4,808 m) as the highest European peak, or use Mount Elbrus (5,642 m) in the Caucasus. Other summits include Mount Kilimanjaro in Kenya, Africa (5,895 m), Vinson Massif in Antarctica (4,892 m), Mount Everest in Asia (8,848 m), Mount McKinley in Alaska, North America (6,194 m), and Mount Aconcagua in Argentina, South America (6,962 m). -
PROLOGUE If I Die, It Will Be in the Most Glorious Place That Nobody
PROLOGUE 2001 If I die, it will be in the most glorious place that nobody has ever seen. I can no longer feel the fingers in my left hand. The glacial Antarctic water has seeped through a tiny puncture in my formerly waterproof glove. If this water were one-tenth of a degree colder, the ocean would become solid. Fighting the knife-edged freeze is depleting my strength, my blood vessels throbbing in a futile attempt to deliver warmth to my extremities. The archway of ice above our heads is furrowed like the surface of a golf ball, carved by the hand of the sea. Iridescent blue, Wedgwood, azure, cerulean, cobalt, and pastel robin’s egg meld with chalk and silvery alabaster. The ice is vibrant, bright, and at the same time ghostly, shadowy. The beauty contradicts the danger. We are the first people to cave dive inside an iceberg. And we may not live to tell the story. It’s February, in the middle of what passes for summer in Antarctica. My job, for National Geographic, is to lead an advanced technical diving team in search of underwater caves deep within the largest moving object on earth, the B-15 iceberg. I had known that diving into tunnels inside this giant piece of ice would be difficult, but I hadn’t calculated that getting out would be nearly impossible. The tidal currents accelerated so quickly that they’ve caged us inside the ice. We’re trapped in this frozen fortress, and I have to figure out how to escape. -
DEATH ZONE FREERIDE About the Project
DEATH ZONE FREERIDE About the project We are 3 of Snow Leopards, who commit the hardest anoxic high altitude ascents and perform freeride from the tops of the highest mountains on Earth (8000+). We do professional one of a kind filming on the utmost altitude. THE TRICKIEST MOUNTAINS ON EARTH NO BOTTLED OXYGEN CHALLENGES TO HUMAN AND NATURE NO EXTERIOR SUPPORT 8000ERS FREERIDE FROM THE TOPS MOVIES ALONE WITH NATURE FREERIDE DESCENTS 5 3 SNOW LEOS Why the project is so unique? PROFESSIONAL FILMING IN THE HARDEST CONDITIONS ❖ Higher than 8000+ m ❖ Under challenging efforts ❖ Without bottled oxygen & exterior support ❖ Severe weather conditions OUTDOOR PROJECT-OF-THE-YEAR “CRYSTAL PEAK 2017” AWARD “Death zone freeride” project got the “Crystal Peak 2017” award in “Outdoor project-of-the-year” nomination. It is comparable with “Oscar” award for Russian outdoor sphere. Team ANTON VITALY CARLALBERTO PUGOVKIN LAZO CIMENTI Snow Leopard. Snow Leopard. Leader The first Italian Snow Leopard. MC in mountaineering. Manaslu of “Mountain territory” club. Specializes in a ski mountaineering. freeride 8163m. High altitude Ski-mountaineer. Participant cameraman. of more than 20 high altitude expeditions. Mountains of the project Manaslu Annapurna Nanga–Parbat Everest K2 8163m 8091m 8125m 8848m 8611m The highest mountains on Earth ❖ 8027 m Shishapangma ❖ 8167 m Dhaulagiri I ❖ 8035 m Gasherbrum II (K4) ❖ 8201 m Cho Oyu ❖ 8051 m Broad Peak (K3) ❖ 8485 m Makalu ❖ 8080 m Gasherbrum I (Hidden Peak, K5) ❖ 8516 m Lhotse ❖ 8091 m Annapurna ❖ 8586 m Kangchenjunga ❖ 8126 m Nanga–Parbat ❖ 8614 m Chogo Ri (K2) ❖ 8156 m Manaslu ❖ 8848 m Chomolungma (Everest) Mountains that we climbed on MANASLU September 2017 The first and unique freeride descent from the altitude 8000+ meters among Russian sportsmen. -
Guideline for Technical Regulation on Hydropower Civil Works
SOCIALIST REPUBLIC OF VIETNAM Ministry of Construction (MOC) Guideline for Technical Regulation on Hydropower Civil Works Design and Construction of Civil Works and Hydromechanical Equipment Final Draft June 2013 Japan International Cooperation Agency Electric Power Development Co., Ltd. Shikoku Electric Power Co., Inc. West Japan Engineering Consultants, Inc. IL CR(2) 13-096 Guideline for QCVN xxxx : 2013/BXD Table of Contents 1. Scope of application .................................................................................................. 1 2. Reference documents ............................................................................................... 1 3. Nomenclatures and definitions ................................................................................. 1 4. Classification of works .............................................................................................. 1 4.1 General stipulation ................................................................................................. 1 4.2 Principles for the classification of hydropower works .............................................. 2 5. Guarantee of serving level of hydropower works .................................................... 7 6. Safety coefficient of hydropower civil works ........................................................... 7 7. Construction of hydropower civil works ................................................................ 26 7.1 General requirements ......................................................................................... -
Deadly High Altitude Pulmonary Disorders: Acute Mountain Sickness
Research Article Int J Pul & Res Sci Volume 1 Issue 1 - April 2016 Copyright © All rights are reserved by Michael Obrowski DOI : 10.19080/IJOPRS.2016.01.555553 Deadly High Altitude Pulmonary Disorders: Acute Mountain Sickness (AMS); High Altitude Pulmonary Edema (HAPE) and High Altitude Cerebral Edema (HACE): A Clinical Review Michael Obrowski1* and Stephanie Obrowski2 1Doctor of Medicine (M.D. – 2000); Assistant Professor of Anatomy; CEO, Chief Physician and Surgeon of Wilderness Physicians, European Union 2Doctor of Medicine (M.D. – 2019); Medical University of Łódź; President of Wilderness Physicians, European Union Submission: January 26, 2016; Published: April 15, 2016 *Corresponding author: Michael Obrowski, M.D., Doctor of Medicine (M.D. – 2000); Assistant Professor of Anatomy; CEO, Chief Physician and Surgeon of Wilderness Physicians, European Union, 43C Żeligowskiego Street, #45, Łódź, Poland 90-644, Email: Abstract Acute Mountain Sickness (AMS); High Altitude Pulmonary Edema (HAPE) and High Altitude Cerebral Edema (HACE). These three disorders, withMountain relatively Sickness, unimportant also smallcalled variationsHigh Altitude seen Sickness, in some isPulmonology specifically aTextbooks, triad of different because disorders, these are inso orderserious, of increasingthey are all seriousness: potentially deadly pulmonary disorders and we will discuss these three major, deadly disorders. Each one, starting with AMS, can progress rapidly to HAPE and then HACE. The two authors of this article have over half a century of high altitude mountaineering experience. They have also alsohad anddisaster still domedicine. have, for Since the lastspring twenty is rapidly years, approaching an NGO, Non-Profit and many Medical “weekend Organization backpackers” (Wilderness will start Physicians going into www.wildernessphysicians. -
Underwater Speleology
... _.__ ._._ ........ _- ..... _---------------. UNDERWATER SPELEOLOGY OFFICIAL NEWSLmER OF THE CAVE DIVING SECTION OF THE NATIONAL SPELEOLOGICAL SOCIETY VOLUME 8 NUMBER 1 Underwater Speleology, vol.8, N9.1 UNDERWATER SPELEOLOGY ON THE COVER ............... Published Bimonthly Beginning in February Sheck Exley (NSS 13146) begins an extensive by exploration of one of the many clear first The Cave Diving Section of magnitude springs in Florida. These springs The National Speleological Society include nine of the ten longest caves in Florida. Photo by John Zumrick (NSS 187B8). c/o Stephen Maegeriein, P. O. Box 60 Williams, Indiana 47470 CALENDAR Deadline for publication is the second Friday of the preceeding month. Send exchange publications and editorial correspondence to the editor: July 12-18 5th International Cave Diving John Zumrick Camp. Contact Sheck Exley, 10259 120 Rusty Gans Dr. Panama City Beach, Florida 32407 Crystal Sprgs Rd., Jacksonvil Ie, Florida 32221 Section membership, including a subscription to un· derwater speleology is open to all members in good stan· July 18-24 8th International Congress of ding of the National Speleological Society at $3.00 per Speleology, Bowling Green, Ky. year. Subscription to non-members is $5.00 per year. Make checks payabie to the NSS Cave Diving Section in For information write Eighth care of the Treasurer. Opinions expresSed in Underwater International Congress of Speleology are not necessarily those of the section or the Speleology, Secretariat, Dept of NSS. Geography and Geology, Western Kentucky Unlv., Bowling Green, Kentucky 42101. EXECUTIVE COMMITTEE ***************RENEWAL TIME?****************** CHAIRPERSON VICE-CHAI RPERSON Dennis Williams (N55 182&11 Karen E. -
Deep Sea Dive Ebook Free Download
DEEP SEA DIVE PDF, EPUB, EBOOK Frank Lampard | 112 pages | 07 Apr 2016 | Hachette Children's Group | 9780349132136 | English | London, United Kingdom Deep Sea Dive PDF Book Zombie Worm. Marrus orthocanna. Deep diving can mean something else in the commercial diving field. They can be found all over the world. Depth at which breathing compressed air exposes the diver to an oxygen partial pressure of 1. Retrieved 31 May Diving medicine. Arthur J. Retrieved 13 March Although commercial and military divers often operate at those depths, or even deeper, they are surface supplied. Minimal visibility is still possible far deeper. The temperature is rising in the ocean and we still don't know what kind of an impact that will have on the many species that exist in the ocean. Guiel Jr. His dive was aborted due to equipment failure. Smithsonian Institution, Washington, DC. Depth limit for a group of 2 to 3 French Level 3 recreational divers, breathing air. Underwater diving to a depth beyond the norm accepted by the associated community. Limpet mine Speargun Hawaiian sling Polespear. Michele Geraci [42]. Diving safety. Retrieved 19 September All of these considerations result in the amount of breathing gas required for deep diving being much greater than for shallow open water diving. King Crab. Atrial septal defect Effects of drugs on fitness to dive Fitness to dive Psychological fitness to dive. The bottom part which has the pilot sphere inside. List of diving environments by type Altitude diving Benign water diving Confined water diving Deep diving Inland diving Inshore diving Muck diving Night diving Open-water diving Black-water diving Blue-water diving Penetration diving Cave diving Ice diving Wreck diving Recreational dive sites Underwater environment. -
Outcomes from the 2015 Round Table on Sepsis
The official daily newsletter of the 35th ISICEM Thursday 19 March 2015 Day 3 Outcomes from the 2015 Round Table on sepsis uring the opening session on Tues- day morning, Simon Finfer (Royal North Shore Hospital of Sydney and Sydney Adventist Hospital, Sydney, Australia) was joined by Steven DOpal (Memorial Hospital of Rhode Island, RI, USA) to summarize the major outcomes of the two-day Round Table discussion “This will be a on sepsis. This was a joint conference significant part of our conducted between ISICEM and the Inter- national Sepsis Forum, with representa- research agenda in the tives from every continent highlighting the future – making sure global nature of the problem. Beginning by addressing the current that our patients are state of knowledge in the epidemiology of doing well after they sepsis, Professor Finfer noted that we know leave the hospital.” surprising little, but that obtaining this data will be crucial if any meaningful strategy is Steven Opal to be developed: “To some degree we have data from developed countries, possibly far less than you would expect or think,” he said. “But there are certainly places in, notably, Africa, where we are completely devoid of data.” The reasons for this lack of data can in part be understood by an appreciation of how patient data are currently characterized and treated, with the Global Burden of Disease Project emerging as a central player in generating evidence and guiding is surprising because we believe that sepsis kills one comes into your ICU with community-acquired global health policy. more people than prostate cancer, breast cancer, pneumonia, you treat the pneumonia; maybe they “The only reference to sepsis in these sta- and many other high profile diseases. -
Mount Everest's Death Zone
Mount Everest’s Death Zone Climate change and crowds of climbers are making the world’s tallest mountain more dangerous than ever Mara Grunbaum ast year, 73-year-old Tamae Watanabe of Japan became the oldest woman to climb Mount Everest, the world’s tallest mountain. In L 2010, 13-year-old Jordan Romero of California became the youngest to reach the top. All sorts of people of varying abilities scale the massive mountain in Asia these days. That may not be a good thing—for Everest or the climbers. Last year, more than 500 people reached the top of the Himalayan mountain, which towers 8,850 meters (29,035 feet) above sea level. Hundreds more climbed partway up. While it’s a great achievement to scale Everest, it can sometimes cause problems for the climbers and the mountain itself. Everest is changing. Warming Up Why is Everest becoming more dangerous to climb? One reason is changes in its environment. Much of the mountain is covered in huge sheets of ice called glaciers. Lately, warmer temperatures in the region have been melting these glaciers. Some places that used to be covered in ice year-round are now completely ice-free in the summer. Shrinking glaciers put climbers at risk. As glaciers melt, snow, ice, and rock are more likely to tumble down the mountain in huge avalanches. These snowslides can injure or even kill climbers. “As it gets warmer, more debris tends to fall down,” says American climbing guide Freddie Wilkinson. He’s one of a number of people who think that climbing Everest is becoming too risky. -
Into the Clouds
Into the Clouds ALSO BY TOD OLSON THE LOST® SERIES: Lost in the Pacific, 1942 Lost in Outer Space Lost in the Amazon Lost in the Antarctic Into the Clouds The Race to Climb the World’s Most Dangerous Mountain TOD OLSON New York Copyright © 2020 by Tod Olson All rights reserved. Published by Scholastic Focus, an imprint of Scholastic Inc., Publishers since 1920. SCHOLASTIC, SCHOLASTIC FOCUS, and associated logos are trademarks and/ or registered trademarks of Scholastic Inc. The publisher does not have any control over and does not assume any responsibility for author or third- party websites or their content. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without written permission of the publisher. For information regarding permission, write to Scholastic Inc., Attention: Permissions Department, 557 Broadway, New York, NY 10012. Library of Congress Cataloging-in-Publication Data Names: Olson, Tod, author. Title: Into the clouds : the race to climb the world’s most dangerous mountain / Tod Olson. Description: New York, NY : Scholastic Focus, 2020. | Audience: Age 10-14. Identifiers: LCCN 2019002127 (print) | LCCN 2019014682 (ebook) | ISBN 9781338207378 (E-book) | ISBN 9781338207361 (hardcover : alk. paper) Subjects: LCSH: K2 (Pakistan : Mountain)—Juvenile literature. | Mountaineering—Pakistan—K2 (Mountain)—Juvenile literature. Classification: LCC GB546.K13 (ebook) | LCC GB546.K13 O55 2020 (print) | DDC -
Wreck Diver Specialty Course Instructor Guide
Instructor Wreck Diver Guide Wreck Diver Specialty Course Instructor Guide Product No. 70232 (Rev. 4/07) Version 2.0 Instructor Guide Wreck Diver PADI Wreck Diver Specialty Course Instructor Guide © PADI 2007 Portions of the Appendix of this guide may be reproduced by PADI Members for use in PADI-sanctioned training, but not for resale or personal gain. No other reproduction is allowed without the express written permission of PADI. Published and distributed by PADI 30151 Tomas Rancho Santa Margarita, CA 92688-2125 USA Printed in U.S.A. Product No. 70232 (04/07) Version 2.0 2 Specialty Course Instructor Guide Instructor Wreck Diver Guide Table of Contents Introduction How to Use this Guide .......................................................................................5 Course Philosophy and Goals .............................................................................5 Course Flow Options .........................................................................................6 Program Options ................................................................................................7 Section One: Course Standards Standards at a Glance .........................................................................................8 Instructor Prerequisites .......................................................................................9 Student Diver Prerequisites ...............................................................................9 Supervision and Ratios .......................................................................................9