Human Factors in High-Altitude Mountaineering
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Human Physiology an Integrated Approach
Gas Exchange and Transport Gas Exchange in the Lungs and Tissues 18 Lower Alveolar P Decreases Oxygen Uptake O2 Diff usion Problems Cause Hypoxia Gas Solubility Aff ects Diff usion Gas Transport in the Blood Hemoglobin Binds to Oxygen Oxygen Binding Obeys the Law of Mass Action Hemoglobin Transports Most Oxygen to the Tissues P Determines Oxygen-Hb Binding O2 Oxygen Binding Is Expressed As a Percentage Several Factors Aff ect Oxygen-Hb Binding Carbon Dioxide Is Transported in Three Ways Regulation of Ventilation Neurons in the Medulla Control Breathing Carbon Dioxide, Oxygen, and pH Infl uence Ventilation Protective Refl exes Guard the Lungs Higher Brain Centers Aff ect Patterns of Ventilation The successful ascent of Everest without supplementary oxygen is one of the great sagas of the 20th century. — John B. West, Climbing with O’s , NOVA Online (www.pbs.org) Background Basics Exchange epithelia pH and buff ers Law of mass action Cerebrospinal fl uid Simple diff usion Autonomic and somatic motor neurons Structure of the brain stem Red blood cells and Giant liposomes hemoglobin of pulmonary Blood-brain barrier surfactant (40X) From Chapter 18 of Human Physiology: An Integrated Approach, Sixth Edition. Dee Unglaub Silverthorn. Copyright © 2013 by Pearson Education, Inc. All rights reserved. 633 Gas Exchange and Transport he book Into Thin Air by Jon Krakauer chronicles an ill- RUNNING PROBLEM fated trek to the top of Mt. Everest. To reach the summit of Mt. Everest, climbers must pass through the “death zone” T High Altitude located at about 8000 meters (over 26,000 ft ). Of the thousands of people who have attempted the summit, only about 2000 have been In 1981 a group of 20 physiologists, physicians, and successful, and more than 185 have died. -
Everest and Oxygen—Ruminations by a Climber Anesthesiologist by David Larson, M.D
Everest and Oxygen—Ruminations by a Climber Anesthesiologist By David Larson, M.D. Gaining Altitude and Losing Partial Pressure with Dave and Samantha Larson Dr. Dave Larson is an obstetric anesthesiologist who practices at Long Beach Memorial Medical Center, and his daughter Samantha is a freshman at Stanford University. Together they have successfully ascended the Seven Summits, the tallest peaks on each of the seven continents, a feat of mountaineering postulated in the 1980s by Richard Bass, owner of the Snowbird Ski Resort in Utah. Bass accomplished it first in 1985. Samantha Larson, who scaled Everest in May 2007 (the youngest non-Sherpa to do so) and the Carstensz Pyramid in August 2007, is at age 18 the youngest ever to have achieved this feat. Because of varying definitions of continental borders based upon geography, geology, and geopolitics, there are nine potential summits, but the Seven Summits is based upon the American and Western European model. Reinhold Messner, an Italian mountaineer known for ascending without supplemental oxygen, postulated a list of Seven Summits that replaced a mountain on the Australian mainland (Mount Kosciuszko—2,228 m) with a higher peak in Oceania on New Guinea (the Carstensz Pyramid—4,884 m). The other variation in defining summits is whether you define Mount Blanc (4,808 m) as the highest European peak, or use Mount Elbrus (5,642 m) in the Caucasus. Other summits include Mount Kilimanjaro in Kenya, Africa (5,895 m), Vinson Massif in Antarctica (4,892 m), Mount Everest in Asia (8,848 m), Mount McKinley in Alaska, North America (6,194 m), and Mount Aconcagua in Argentina, South America (6,962 m). -
DEATH ZONE FREERIDE About the Project
DEATH ZONE FREERIDE About the project We are 3 of Snow Leopards, who commit the hardest anoxic high altitude ascents and perform freeride from the tops of the highest mountains on Earth (8000+). We do professional one of a kind filming on the utmost altitude. THE TRICKIEST MOUNTAINS ON EARTH NO BOTTLED OXYGEN CHALLENGES TO HUMAN AND NATURE NO EXTERIOR SUPPORT 8000ERS FREERIDE FROM THE TOPS MOVIES ALONE WITH NATURE FREERIDE DESCENTS 5 3 SNOW LEOS Why the project is so unique? PROFESSIONAL FILMING IN THE HARDEST CONDITIONS ❖ Higher than 8000+ m ❖ Under challenging efforts ❖ Without bottled oxygen & exterior support ❖ Severe weather conditions OUTDOOR PROJECT-OF-THE-YEAR “CRYSTAL PEAK 2017” AWARD “Death zone freeride” project got the “Crystal Peak 2017” award in “Outdoor project-of-the-year” nomination. It is comparable with “Oscar” award for Russian outdoor sphere. Team ANTON VITALY CARLALBERTO PUGOVKIN LAZO CIMENTI Snow Leopard. Snow Leopard. Leader The first Italian Snow Leopard. MC in mountaineering. Manaslu of “Mountain territory” club. Specializes in a ski mountaineering. freeride 8163m. High altitude Ski-mountaineer. Participant cameraman. of more than 20 high altitude expeditions. Mountains of the project Manaslu Annapurna Nanga–Parbat Everest K2 8163m 8091m 8125m 8848m 8611m The highest mountains on Earth ❖ 8027 m Shishapangma ❖ 8167 m Dhaulagiri I ❖ 8035 m Gasherbrum II (K4) ❖ 8201 m Cho Oyu ❖ 8051 m Broad Peak (K3) ❖ 8485 m Makalu ❖ 8080 m Gasherbrum I (Hidden Peak, K5) ❖ 8516 m Lhotse ❖ 8091 m Annapurna ❖ 8586 m Kangchenjunga ❖ 8126 m Nanga–Parbat ❖ 8614 m Chogo Ri (K2) ❖ 8156 m Manaslu ❖ 8848 m Chomolungma (Everest) Mountains that we climbed on MANASLU September 2017 The first and unique freeride descent from the altitude 8000+ meters among Russian sportsmen. -
Deadly High Altitude Pulmonary Disorders: Acute Mountain Sickness
Research Article Int J Pul & Res Sci Volume 1 Issue 1 - April 2016 Copyright © All rights are reserved by Michael Obrowski DOI : 10.19080/IJOPRS.2016.01.555553 Deadly High Altitude Pulmonary Disorders: Acute Mountain Sickness (AMS); High Altitude Pulmonary Edema (HAPE) and High Altitude Cerebral Edema (HACE): A Clinical Review Michael Obrowski1* and Stephanie Obrowski2 1Doctor of Medicine (M.D. – 2000); Assistant Professor of Anatomy; CEO, Chief Physician and Surgeon of Wilderness Physicians, European Union 2Doctor of Medicine (M.D. – 2019); Medical University of Łódź; President of Wilderness Physicians, European Union Submission: January 26, 2016; Published: April 15, 2016 *Corresponding author: Michael Obrowski, M.D., Doctor of Medicine (M.D. – 2000); Assistant Professor of Anatomy; CEO, Chief Physician and Surgeon of Wilderness Physicians, European Union, 43C Żeligowskiego Street, #45, Łódź, Poland 90-644, Email: Abstract Acute Mountain Sickness (AMS); High Altitude Pulmonary Edema (HAPE) and High Altitude Cerebral Edema (HACE). These three disorders, withMountain relatively Sickness, unimportant also smallcalled variationsHigh Altitude seen Sickness, in some isPulmonology specifically aTextbooks, triad of different because disorders, these are inso orderserious, of increasingthey are all seriousness: potentially deadly pulmonary disorders and we will discuss these three major, deadly disorders. Each one, starting with AMS, can progress rapidly to HAPE and then HACE. The two authors of this article have over half a century of high altitude mountaineering experience. They have also alsohad anddisaster still domedicine. have, for Since the lastspring twenty is rapidly years, approaching an NGO, Non-Profit and many Medical “weekend Organization backpackers” (Wilderness will start Physicians going into www.wildernessphysicians. -
Outcomes from the 2015 Round Table on Sepsis
The official daily newsletter of the 35th ISICEM Thursday 19 March 2015 Day 3 Outcomes from the 2015 Round Table on sepsis uring the opening session on Tues- day morning, Simon Finfer (Royal North Shore Hospital of Sydney and Sydney Adventist Hospital, Sydney, Australia) was joined by Steven DOpal (Memorial Hospital of Rhode Island, RI, USA) to summarize the major outcomes of the two-day Round Table discussion “This will be a on sepsis. This was a joint conference significant part of our conducted between ISICEM and the Inter- national Sepsis Forum, with representa- research agenda in the tives from every continent highlighting the future – making sure global nature of the problem. Beginning by addressing the current that our patients are state of knowledge in the epidemiology of doing well after they sepsis, Professor Finfer noted that we know leave the hospital.” surprising little, but that obtaining this data will be crucial if any meaningful strategy is Steven Opal to be developed: “To some degree we have data from developed countries, possibly far less than you would expect or think,” he said. “But there are certainly places in, notably, Africa, where we are completely devoid of data.” The reasons for this lack of data can in part be understood by an appreciation of how patient data are currently characterized and treated, with the Global Burden of Disease Project emerging as a central player in generating evidence and guiding is surprising because we believe that sepsis kills one comes into your ICU with community-acquired global health policy. more people than prostate cancer, breast cancer, pneumonia, you treat the pneumonia; maybe they “The only reference to sepsis in these sta- and many other high profile diseases. -
Mount Everest's Death Zone
Mount Everest’s Death Zone Climate change and crowds of climbers are making the world’s tallest mountain more dangerous than ever Mara Grunbaum ast year, 73-year-old Tamae Watanabe of Japan became the oldest woman to climb Mount Everest, the world’s tallest mountain. In L 2010, 13-year-old Jordan Romero of California became the youngest to reach the top. All sorts of people of varying abilities scale the massive mountain in Asia these days. That may not be a good thing—for Everest or the climbers. Last year, more than 500 people reached the top of the Himalayan mountain, which towers 8,850 meters (29,035 feet) above sea level. Hundreds more climbed partway up. While it’s a great achievement to scale Everest, it can sometimes cause problems for the climbers and the mountain itself. Everest is changing. Warming Up Why is Everest becoming more dangerous to climb? One reason is changes in its environment. Much of the mountain is covered in huge sheets of ice called glaciers. Lately, warmer temperatures in the region have been melting these glaciers. Some places that used to be covered in ice year-round are now completely ice-free in the summer. Shrinking glaciers put climbers at risk. As glaciers melt, snow, ice, and rock are more likely to tumble down the mountain in huge avalanches. These snowslides can injure or even kill climbers. “As it gets warmer, more debris tends to fall down,” says American climbing guide Freddie Wilkinson. He’s one of a number of people who think that climbing Everest is becoming too risky. -
Into the Clouds
Into the Clouds ALSO BY TOD OLSON THE LOST® SERIES: Lost in the Pacific, 1942 Lost in Outer Space Lost in the Amazon Lost in the Antarctic Into the Clouds The Race to Climb the World’s Most Dangerous Mountain TOD OLSON New York Copyright © 2020 by Tod Olson All rights reserved. Published by Scholastic Focus, an imprint of Scholastic Inc., Publishers since 1920. SCHOLASTIC, SCHOLASTIC FOCUS, and associated logos are trademarks and/ or registered trademarks of Scholastic Inc. The publisher does not have any control over and does not assume any responsibility for author or third- party websites or their content. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without written permission of the publisher. For information regarding permission, write to Scholastic Inc., Attention: Permissions Department, 557 Broadway, New York, NY 10012. Library of Congress Cataloging-in-Publication Data Names: Olson, Tod, author. Title: Into the clouds : the race to climb the world’s most dangerous mountain / Tod Olson. Description: New York, NY : Scholastic Focus, 2020. | Audience: Age 10-14. Identifiers: LCCN 2019002127 (print) | LCCN 2019014682 (ebook) | ISBN 9781338207378 (E-book) | ISBN 9781338207361 (hardcover : alk. paper) Subjects: LCSH: K2 (Pakistan : Mountain)—Juvenile literature. | Mountaineering—Pakistan—K2 (Mountain)—Juvenile literature. Classification: LCC GB546.K13 (ebook) | LCC GB546.K13 O55 2020 (print) | DDC -
Catalogue 48: June 2013
Top of the World Books Catalogue 48: June 2013 Mountaineering Fiction. The story of the struggles of a Swiss guide in the French Alps. Neate X134. Pete Schoening Collection – Part 1 Habeler, Peter. The Lonely Victory: Mount Everest ‘78. 1979 Simon & We are most pleased to offer a number of items from the collection of American Schuster, NY, 1st, 8vo, pp.224, 23 color & 50 bw photos, map, white/blue mountaineer Pete Schoening (1927-2004). Pete is best remembered in boards; bookplate Ex Libris Pete Schoening & his name in pencil, dj w/ edge mountaineering circles for performing ‘The Belay’ during the dramatic descent wear, vg-, cloth vg+. #9709, $25.- of K2 by the Third American Karakoram Expedition in 1953. Pete’s heroics The first oxygenless ascent of Everest in 1978 with Messner. This is the US saved six men. However, Pete had many other mountain adventures, before and edition of ‘Everest: Impossible Victory’. Neate H01, SB H01, Yak H06. after K2, including: numerous climbs with Fred Beckey (1948-49), Mount Herrligkoffer, Karl. Nanga Parbat: The Killer Mountain. 1954 Knopf, NY, Saugstad (1st ascent, 1951), Mount Augusta (1st ascent) and King Peak (2nd & 1st, 8vo, pp.xx, 263, viii, 56 bw photos, 6 maps, appendices, blue cloth; book- 3rd ascents, 1952), Gasherburm I/Hidden Peak (1st ascent, 1958), McKinley plate Ex Libris Pete Schoening, dj spine faded, edge wear, vg, cloth bookplate, (1960), Mount Vinson (1st ascent, 1966), Pamirs (1974), Aconcagua (1995), vg. #9744, $35.- Kilimanjaro (1995), Everest (1996), not to mention countless climbs in the Summarizes the early attempts on Nanga Parbat from Mummery in 1895 and Pacific Northwest. -
Safe Sojourns to High Altitudes: the Risks of Annual Religious Pilgrimages in Jammu and Kashmir, India- Clinical Diagnostics and Treatment
Research Article JOJ Pub Health Volume 2 Issue 1 - May 2017 Copyright © All rights are reserved by SM Kadri Safe Sojourns to High Altitudes: The Risks of Annual Religious Pilgrimages in Jammu and Kashmir, India- Clinical Diagnostics and Treatment SM Kadri1*, Saleem-ur-Rehman2, Michael W Popejoy3 and Christoph S Eberle4 1Division of Epidemiology and Public Health, Integrated Disease Surveillance Programme, India 2Department of Health Services, Fellow WHO Director, India 3Department of Health Promotion and Disease Prevention, Florida International University, USA 4National Academy of Clinical Biochemistry, Associate Fellow, USA Submission: May 04, 2017; Published: May 26, 2017 *Corresponding author: SM Kadri, Division of Epidemiology and Public Health, RFPTC Building, Barzulla, Srinagar 190005, Kashmir, India, Email: Abstract increasing prevalence for this type of illness. In The behavioral characteristics of high altitude climbers and the precautions necessary to This article addresses the clinical diagnosis and clinical treatment plan for several diseases that afflict high altitude climbers and the described; then, the common treatment regimens for climbermal adaptation for high altitude sickness are covered. The conclusion explored inprevent the discussion death from is thatthe high no one altitude need sportdie from activities high altitude are introduced; sickness iffirst; proper then. planning The clinical and manifestationsgood judgment ofare different applied diseaseto climbing complexes protocols; are and, that these rules are -
A Fundamental Concept in COVID-19 Lung Disease
1 Pneumolysis: a fundamental concept in COVID-19 lung disease Gustavo R. Zubieta-Calleja1, Natalia Zubieta-DeUrioste1, Felipe de Jesús Montelongo2, Manuel Gabriel Romo Sanchez2 & Murray Epstein3 1. High Altitude Pulmonary and Pathology Institute (IPPA), La Paz, Bolivia. 2. Hospital General de Ecatepec “Las Américas”, ISEM, México 3. University of Miami Miller School of Medicine, Miami, USA Keywords: HAPE, SARS-CoV-2, ACE-2, EPO, Lung sequelae, Kawasaki disease COVID-19 tongue Running title: Pneumolysis in COVID-19 lung disease Corresponding author: Prof. Dr. Gustavo R. Zubieta-Calleja Director High Altitude Pulmonary and Pathology Institute (HAPPI-IPPA) www.Altitudeclinic.com Av. Copacabana - Prolongación # 55, Teleféricos Celeste y Blanco, Estación Av. Del Poeta, La Paz, Bolivia. E-mail: [email protected]; Cel: 591-73258026. Prof. Dr. Gustavo Zubieta-Calleja ORCID: 0000-0002-4283-6514 Dr. Natalia Zubieta-DeUrioste ORCID: 0000-0003-2675-5025 Declaration of interest: None. Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not- for-profit sectors. 2 ABSTRACT Background COVID-19 severe lung compromise often evolves to life-threatening hypoxia. The experience led to the implementation of standardized protocols assuming similarity to SARS-CoV. Impulsive use of ventilators ended in up to 88% fatality. Methods COVID-19 pathophysiology and histopathological lung biopsy photomicrographs are analyzed. Results Pneumolysis is defined as progressive alveolar-capillary destruction resulting from the CoV-2 attack on pneumocytes. The histopathological results show the presence of Masson bodies, alveolar coating cells with nuclear atypia, reactive pneumocytes, reparative fibrosis, intra- alveolar hemorrhage, moderate inflammatory infiltrates, microabscesses, microthrombus, hyaline membrane remnants, and emphysema. -
1953 Conquest of Mount Everest
1953 Conquest of Mount Everest Mount Everest is in the Himalaya mountain range located between Nepal and Tibet, an autonomous region of China. At 8,849 meters (29,032 feet), it is considered the tallest point on Earth. In the 19th century, the mountain was named after George Everest, a former Surveyor General of India. The Tibetan name is Chomolungma, which means “Mother Goddess of the World.” The Nepali name is Sagarmatha. The 1953 British Mount Everest expedition was the ninth to attempt the first ascent and the first confirmed to have succeeded when Sherpa Tenzing Norgay and (later Sir) Edmund Hillary reached the summit on 29 May 1953. Led by Colonel John Hunt, it was organised and financed by the Joint Himalayan Committee. News of the expedition's success reached London in time to be released on the morning of Queen Elizabeth II's coronation on 2nd June. The conquest of Everest caught the imagination of the world. So, there are many commemorative & souvenir issues & first day covers. Consequently, it can make a good philatelic theme. This display shows just a small selection of what is available. This Indian first day cover shows a photo, taken by Edmund Hillary, of Sherpa Tenzing Norgay on the summit. Postcard - Edmund Hillary, Tenzing Norgay & Sir John Hunt’s Expedition Team Sir John Hunt (L), leader of the British Everest expedition, and Sir Edmund Hillary (R) arrive at Lancaster House for reception being given in their honour. Earlier they had been received by Queen Elizabeth who knighted the two men. Edmund Hilary Quotes “People do not decide to become extraordinary. -
The Modernisation of Elite British Mountaineering
The Modernisation of Elite British Mountaineering: Entrepreneurship, Commercialisation and the Career Climber, 1953-2000 Thomas P. Barcham Thesis submitted in partial fulfilment of the requirements of De Montfort University for the degree of Doctor of Philosophy Submission date: March 2018 Contents Abstract ................................................................................................................................................... 4 Acknowledgments ................................................................................................................................... 5 Table of Abbreviations and Acronyms .................................................................................................... 6 Table of Figures ....................................................................................................................................... 7 Chapter 1. Introduction .......................................................................................................................... 8 Literature Review ............................................................................................................................ 14 Definitions, Methodology and Structure ........................................................................................ 29 Chapter 2. 1953 to 1969 - Breaking a New Trail: The Early Search for Earnings in a Fast Changing Pursuit ..................................................................................................................................................