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Product List 2018 WE LIVE SERVICE Certificates quartett owns a production site that is certified according to EN ISO 9001:2008 Quality management systems - Requirements EN ISO 13485:2012 + AC:2012 Medical devices - Quality management systems - Requirements for regulatory purposes GMP Conformity Our quality management guarantees products of highest quality! 2 Foreword to the quartett product list quartett Immunodiagnostika, Biotechnologie + Kosmetik Vertriebs GmbH welcomes you as one of our new business partners as well as all of our previous loyal clients. You are now member of quartett´s worldwide customers. Founded as a family-run company in 1986, quartett ensures for more than 30 years consistent quality of products. In the end 80´s quartett offered radioimmunoassay and enzyme immunoassay kits from different manufacturers in the USA. In the beginning 90´s the company changed its strategy from offering products for routine diagnostic to the increasing field of research and development. Setting up a production plant in 1997 supported this decision. The company specialized its product profile in manufacturing and modification of synthetic peptides with HPLC purity > 95 % including protease inhibitors or peptides for antibody production. Second expertise of quartett is the production of a variety of reagents for histology, cytology and immunohistochemistry including > 8000 antibodies and detection systems. All products are exclusively manufactured in Germany without outsourcing any production step. Nowadays, we expand into all other diagnostic and research fields and supply our customers in universities, government institutes, pharmaceutical and biotechnological companies, hospitals and private doctor offices. But we are not only limited to provide our customers with consumable chemicals. Since quartett already offered cosmetic peptides, in 2011 we started working in the cosmetic field creating YOUmeDERM® care products. We have set ourselves the task to provide the best quality solutions in all spheres of research. quartett owns a production site that is certified according to EN ISO 9001:2008 & EN ISO 13485:2012 + AC:2012 and works in compliance with GMP conformity. Our quality management guarantees products of highest quality. Over the past decades we have steadily improved and enhanced our capabilities to satisfy your expectations. Service and support of our valued customers are our daily businesses. A network of worldwide distributors guarantees global customer supply. We participate at international exhibitions, such as MedLab in Dubai, Medica in Germany and various congresses for pathologists. Furthermore, we are represented by distributors at exhibitions we are not able to attend. After so many years it is again time to say thanks to each of our clients and business partners for trusting in us. Without them we were not as successful as we are and we are proud to have each of you in our quartett family. Welcome to quartett! Be part of us! 3 1. Antibodies 7 1.1. Antibodies for FFPE and Frozen Sections 7 1.2. Antibodies FITC-conjugated 172 2. Immunohistochemical Detection Systems 174 2.1. Streptavidin / Biotin Systems - ProTaqs® Essencial 175 2.2. Polymer Systems - ProTaqs® Suprema PolyColor 175 2.3. Polymer Systems - ProTaqs® Suprema DoubleStain 177 2.4. Polymer Systems - ProTaqs® Suprema TripleStain 179 2.5. Single Components for Immunhistochemical Detection Systems 180 2.5.1. Streptavidin and Enzyme Complexes 180 2.5.2. Secondary Antibodies 180 2.5.3. Secondary Antibodies for Double Staining Detection Systems 180 2.5.4. Chromogens for Alkaline Phosphatase 181 2.5.5. Chromogens for Horseradish Peroxidase 181 2.5.6. Sera 181 2.5.7. Chromogen Dilution Solutions 182 3. Reagents for Immunohistochemistry / Histology / Cytology 183 3.1. Histological / Cytological Stains 183 3.1.1. Stain Solutions 183 3.1.2. Fast Stains 184 3.1.3. Special Stains 185 3.2. Buffer 186 3.2.1. Buffer Bags with Pre-mixed Salts 187 3.2.2. Citrate Buffer / Citrate EDTA Buffer / EDTA Buffer 187 3.2.3. Michel’s Buffer 188 3.2.4. Phosphate Buffered Saline / PBS 188 3.2.5. TRIS Buffered Saline / TBS 190 3.2.6. TRIS EDTA Buffer / TRIS EDTA Citrate Buffer 191 3.2.7. Buffer for Electrophoresis 192 3.3. Antigen Retrieval 193 3.4. Antibody Diluents 194 3.5. Blocking Reagents 195 3.6. Mounting Media 195 3.7. Fixatives 196 3.8. Decalcifier 197 3.9. Intermedium - Xylene Alternative ProTaqs® Clear 198 4. Instruments for Histology 200 4.1. Humidity Chamber - Slide Humidore 200 4.2. Tissue Float Bath 3 in 1 *** IVD *** 201 5. Molecularbiology and In-situ-Hybridization jelly 202 by FProISHTaqs® 5.1. Fluorescence-In-situ-Hybridization (FISH) 202 5.1.1. ProTaqs® jellyFISH Probes 203 5.1.2. Pretreatment and FISH on Paraffin Tissues 206 5.2. Wash Solutions and Buffer 206 6. Accessories for Anatomy and Pathology 207 4 7. Peptides 209 7.1. Enzyme Inhibitors 209 7.1.1. Protease Inhibitors 209 7.1.2. Protease Inhibitor Cocktail Kits 216 7.1.3. Protease and Phosphatase Inhibitor Cocktail Kits 217 7.2. Collagenase Inhibitors 218 8. Services 219 8.1. Peptide Services 219 8.1.1. Custom Peptide Synthesis 219 8.1.2. Modification and Derivatization of Peptides 220 8.1.3. Isolation and Purifcation of Peptides 220 8.2. Sugar Amino Acids (SAAs) 221 8.3. Carbohydrates 221 8.4. Nucleosides 221 8.5. Custom Antibody Production Services 221 8.5.1. Polyclonal Antisera and Antibodies from Rabbit 221 8.5.2. Monoclonal Mouse Antibodies 222 8.5.3. Monoclonal Rabbit Antibodies 222 8.5.4. Modification of Mono- and Polyclonal Antibodies 222 9. Cosmetics 223 9.1. YOUmeDERM® Care Products 223 10. Conditions of Supply 226 10.1. Address 226 10.2. Orders 226 10.3. Shipments 226 10.4. Shipping Charges 226 10.5. Prices 226 10.6. Payment and Credit Terms 227 10.7. Returns and Cancellations 227 10.8. Limited Warranty 227 10.9. Breakages and Shortages 227 10.10. Reservation of Property Rights 227 10.11. Liabilities and Conditions 227 10.12. Applicable Law, Jurisdiction and Partial Invalidity 227 10.13. Technical Support 227 5 Explanations AP Alkaline Phosphatase Bov Bovine Ch Chicken Ct Cat Conc. Concentrate Cw Cow Dg Dog Du Duck EIA Enzymimmunoassay ELISA Enzyme-linked Immunosorbent Assay FACS Fluorescence-activated Cell Sorting FISH Fluorescence In-situ Hybridization Fs Fish Gp Guinea Pig Gt Goat HIER Heat Induced Epitope Retrieval Hm Hamster Hs Horse HRP Horseradish Peroxidase Hu Human IC or ICC Immunocytochemistry IF Immunofluorescence IH Immunohistology IHC(p,f) Immunohistochemistry (Paraffin, Frozen) IP Immunoprecipitation ISH In-Situ Hybridization LSAB Labeled Streptavidin / Biotin method mM Reacts w. most mammals Mk Monkey Ms Mouse Ov Ovine PIER Proteolytic Induced Epitope Retrieval Pg Pig Rb Rabbit RIA Radioimmunoassay Rt Rat RTU Ready-to-use Sam Salamander Sh Sheep WB Western Blot 6 1. Antibodies A 1.1. Antibodies for FFPE and Frozen Sections quartett offers more than 8000 antibodies for formalin fixed paraffin embedded and frozen sections. Almost all antibodies are available in the same formats. If you want to place an order, please follow our intructions for catalog number writing using the article master shown in the table. Example: Article Master: PR292; Product Name: PD-L1 (QR1) ▶ 100 µl concentrate: 1-PR292-02 ▶ 1 ml concentrate: 1-PR292-07 ▶ 3 ml ready-to-use: 2-PR292-10 ▶ 7 ml ready-to-use: 2-PR292-13 Just ask our customer service team for the correct order number, if you have difficulties or if you need another size than shown here. Cat. No. Product Name Source Clone Application Reactivity 00001 14-3-3 epsilon Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rb, Rt, ... 00002 14-3-3 pan (alpha, beta, gamma, delta, epsilon) Rb Polyclonal IHC(p*/f), WB Hu, Ms, Rt, ... 00003 14-3-3 pan (alpha, beta, gamma, delta, epsilon) Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... 00004 14-3-3 zeta Rb Polyclonal IHC(p*/f), WB Hu, Ms, Rt, ... 00005 2-aminoethanethiol dioxygenase/ADO Rb Polyclonal IHC(p*/f), WB Hu, Ms, Rt, ... 00006 2-oxoglutarate and iron dependent oxygenase domain contai- Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rb, Rt, ... ning 1/OGFOD1 00007 2-oxoglutarate and iron dependent oxygenase domain contai- Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... ning 2/OGFOD2 00008 2',3'-cyclic nucleotide 3' phosphodiesterase/CNP Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rb, Rt, ... 00009 2',5'-oligoadenylate synthetase 1/OAS1 Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, ... 00010 20S proteasome beta type subunit antibody proteasome com- Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... ponent C5/PRS3 00011 26S proteasome associated UCH interacting protein 1/UCH- Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... L5IP 00012 26S proteasome regulatory subunit S10/PSMD6 Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rb, Rt, ... 00013 3-hydroxyanthranilate oxygenase/HAAO Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... 00014 3-oxoacid CoA transferase 1/OXCT1 Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... 00015 3-phosphoglycerate dehydrogenase/PHGDH Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... 00016 4-N acetylglucosaminyltransferase/A4GNT Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... 00017 4'-phosphopantetheinyl transferase/AASDHPPT Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rb, Rt, ... 00019 5-methyl cytosine Rb Polyclonal IHC(p*/f), ELISA 00020 6-phosphofructo-1-kinase/fructose-1,6-bisphosphatase/PFK1 Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rb, Rt, ... 00021 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1/ Rb Polyclonal IHC(p*/f), ELISA, WB Hu, Ms, Rt, ... PFKFB1 Errors and misprints excepted. If you need help with the catalog number, just ask our customer service team.
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    Cellular and Molecular Signatures in the Disease Tissue of Early Rheumatoid Arthritis Stratify Clinical Response to csDMARD-Therapy and Predict Radiographic Progression Frances Humby1,* Myles Lewis1,* Nandhini Ramamoorthi2, Jason Hackney3, Michael Barnes1, Michele Bombardieri1, Francesca Setiadi2, Stephen Kelly1, Fabiola Bene1, Maria di Cicco1, Sudeh Riahi1, Vidalba Rocher-Ros1, Nora Ng1, Ilias Lazorou1, Rebecca E. Hands1, Desiree van der Heijde4, Robert Landewé5, Annette van der Helm-van Mil4, Alberto Cauli6, Iain B. McInnes7, Christopher D. Buckley8, Ernest Choy9, Peter Taylor10, Michael J. Townsend2 & Costantino Pitzalis1 1Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Departments of 2Biomarker Discovery OMNI, 3Bioinformatics and Computational Biology, Genentech Research and Early Development, South San Francisco, California 94080 USA 4Department of Rheumatology, Leiden University Medical Center, The Netherlands 5Department of Clinical Immunology & Rheumatology, Amsterdam Rheumatology & Immunology Center, Amsterdam, The Netherlands 6Rheumatology Unit, Department of Medical Sciences, Policlinico of the University of Cagliari, Cagliari, Italy 7Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow G12 8TA, UK 8Rheumatology Research Group, Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham B15 2WB, UK 9Institute of