Datasheet BA3564-2 Anti-FES Antibody

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Product datasheet Anti-FES Antibody Catalog Number: BA3564-2 BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected] Basic Information Product Name Anti-FES Antibody Gene Name FES Source Rabbit IgG Species Reactivity human,mouse,rat Tested Application WB Contents 500ug/ml antibody with PBS ，0.02% NaN3 , 1mg BSA and 50% glycerol. Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human FES(808-822aa STIYQELQSIRKRHR). Purification Immunogen affinity purified. Observed MW Dilution Ratios Western blot: 1:500-2000 Storage 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing Background Information FES(feline sarcoma oncogene) is an enzyme that in humans is encoded by the FES gene, also known as Proto-oncogene tyrosine-protein kinase Fes/Fps, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes c-fes/fps protein, FPS, Oncogene FES, feline sarcoma virus, FPS. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. Non-onc intervening sequences were present in the human counterpart. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of°Cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Reference Anti-FES Antibody被引用在0文献中。暂无引用 FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC AND CLINICAL USE. 1 Product datasheet Anti-FES Antibody Catalog Number: BA3564-2 BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected] Selected Validation Data FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC AND CLINICAL USE. 2 Powered by TCPDF (www.tcpdf.org).

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Katalog 2015 Cover Paul Lin *Hinweis Förderung.Indd
Product List 2015 WE LIVE SERVICE Certificates quartett owns two productions sites that are certified according to EN ISO 9001:2008 Quality management systems - Requirements EN ISO 13485:2012 + AC:2012 Medical devices - Quality management systems - Requirements for regulatory purposes GMP Conformity Our quality management guarantees products of highest quality! 2 Foreword to the quartett product list 2015 quartett Immunodiagnostika, Biotechnologie + Kosmetik Vertriebs GmbH welcomes you as one of our new business partners as well as all of our previous loyal clients. You are now member of quartett´s worldwide customers. First of all we would like to introduce ourselves to you. Founded as a family-run company in 1986, quartett ensures for more than a quarter of a century consistent quality of products. Service and support of our valued customers are our daily businesses. And we will continue! In the end 80´s quartett offered radioimmunoassay and enzyme immunoassay kits from different manufacturers in the USA. In the beginning 90´s the company changed its strategy from offering products for routine diagnostic to the increasing field of research and development. Setting up a production plant in 1997 and a second one in 2011 supported this decision. The company specialized its product profile in the field of manufacturing synthetic peptides for antibody production, peptides such as protease inhibitors, biochemical reagents and products for histology, cytology and immunohistology. All products are exclusively manufactured in Germany without outsourcing any production step. Nowadays, we expand into all other diagnostic and research fields and supply our customers in universities, government institutes, pharmaceutical and biotechnological companies, hospitals, and private doctor offices.
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Supplementary Table 1. in Vitro Side Effect Profiling Study for LDN/OSU-0212320. Neurotransmitter Related Steroids
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Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia
cancers Review Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia Kalpana K. Bhanumathy 1,*, Amrutha Balagopal 1, Frederick S. Vizeacoumar 2 , Franco J. Vizeacoumar 1,3, Andrew Freywald 2 and Vincenzo Giambra 4,* 1 Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; [email protected] (A.B.); [email protected] (F.J.V.) 2 Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; [email protected] (F.S.V.); [email protected] (A.F.) 3 Cancer Research Department, Saskatchewan Cancer Agency, 107 Wiggins Road, Saskatoon, SK S7N 5E5, Canada 4 Institute for Stem Cell Biology, Regenerative Medicine and Innovative Therapies (ISBReMIT), Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, FG, Italy * Correspondence: [email protected] (K.K.B.); [email protected] (V.G.); Tel.: +1-(306)-716-7456 (K.K.B.); +39-0882-416574 (V.G.) Simple Summary: Protein phosphorylation is a key regulatory mechanism that controls a wide variety of cellular responses. This process is catalysed by the members of the protein kinase su- perfamily that are classiﬁed into two main families based on their ability to phosphorylate either tyrosine or serine and threonine residues in their substrates. Massive research efforts have been invested in dissecting the functions of tyrosine kinases, revealing their importance in the initiation and progression of human malignancies. Based on these investigations, numerous tyrosine kinase inhibitors have been included in clinical protocols and proved to be effective in targeted therapies for various haematological malignancies.
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FES Rabbit Polyclonal Antibody – TA590713 | Origene
OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA590713 FES Rabbit Polyclonal Antibody Product data: Product Type: Primary Antibodies Applications: ELISA, WB Recommended Dilution: WB 1:20000, ELISA 1:100-1:2000 Reactivity: Human Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: DNA immunization. This antibody is specific for the Middle Region of the target protein. Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 Concentration: 0.83mg/ml Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Gene Name: FES proto-oncogene, tyrosine kinase Database Link: NP_001996 Entrez Gene 2242 Human P07332 This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 FES Rabbit Polyclonal Antibody – TA590713 Background: FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses.
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Supp Tables.Pdf
Supplementary Table 1. Complete list of 1,628 human samples included in the study Normal Tissues Tumorigenic Samples Non-cancerous diseases n n n (n: 424) (n: 1054) (n: 150) Primary tissues (n: 390) Solid tumors (n: 611) Aorta (n: 18) Aorta 2 Bladder 44 Atherosclerotic lesions 18 Apheresis 4 Breast 76 Bladder 8 Cervix 4 Blood (n: 86) Blood 180 Colon 110 Lupus 7 Bone marrow 14 Endometrium 68 Autism 30 Brain 6 Esophagus 13 Alzheimer 35 Breast 2 Ganglioneurom 1 Primary biliary cirrhosis (PBC) 4 Buccal epithelium 21 Glioma 90 Systemic sclerosis (SSc) 10 Cerebellum 1 Head-neck 9 Cervix 1 Kidney 5 Brain (n: 26) Colon 97 Liver 19 Alzheimer 11 Endometrium 2 Melanoma 21 Dementia (with Lewy bodies) 13 Esophagus 5 Neuroblastoma 16 Parkinson 1 Fetal brain 1 Non-small Cell Lung Carcinoma 23 Heart 2 Ovarian 30 Muscle (n: 17) Liver 5 Pancreas* 29 Myopathies 17 Lung 3 Prostate 14 Muscle 5 Stomach 16 Ovary 2 Testis 23 Immunodeficiency, Centromere Pancreas 7 instability and Facial anomalies Prostate 5 Hematologic malignancies (n: 244) syndrome (ICF syndrome) 4 Skin 5 Acute lymphoblastic leukemia (ALL) 58 Stomach 7 Acute myeloblastic leukemia (AML) 34 Suprarenal gland 1 Chronic lymphocytic leukemia (CLL) 25 Testis 4 Diffuse large B-cell lymphoma (DLBCL) 49 Follicular lymphoma (FL) 14 Normal cell lines (n: 7) Mantle cell lymphoma (MCL) 10 Lymphoblastoid 6 Molecular Burkitt's lymphoma (mBL) 18 Melanocyte 1 Multiple myeloma (MM) 14 Myeloproliferative syndromes (MDS/MPS) 13 Stem Cells (n: 27) Mixed lineage leukemia 9 Adult 19 Embryonic 8 Metastases (n:50) Colon to Liver 32 Colon to Brain 13 Kidney to Brain 5 Premalignant lesions (n: 25) Adenomas (colon) 12 Breast 7 Endometrium hyperplasia 6 Cancer cell lines (n: 82) Breast 6 Cervix 4 Colon 10 Esophagus 2 Head-neck 2 Leukemia 3 Liver 3 Lung 10 Lymphoma 23 Melanocyte 2 Neuroblastoma 2 Pancreas 12 Prostate 3 Carcinoma of unknow primary (CUP) 42 Supplementary Table 2.
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Protein Kinase
Flexi® ORF Clone www.promega.co.jp/flexiclone/ Protein Kinase 355個（2012/4/1 現在）遺伝子シンボル説明 FXC_PID 価格 FHC_PID 価格 AAK1 AP2 associated kinase 1 FXC00722 ¥40,000 FHC00722 ¥50,000 AATK apoptosis-associated tyrosine kinase FXC04004 ¥40,000 FHC04004M ¥60,000 ABL1 c-abl oncogene 1, receptor tyrosine kinase FXC01406 ¥40,000 FHC01406 ¥50,000 ACTR2 ARP2 actin-related protein 2 homolog (yeast) FXC02146 ¥40,000 FHC02146 ¥50,000 Activin receptor type-1 Precursor (EC 2.7.11.30)(Activin receptor type I)(ACTR-I)(Serine/threonine-protein kinase ACVR1 FXC03971 ¥40,000 FHC03971 ¥50,000 receptor R1)(SKR1)(Activin receptor-like kinase 2)(ALK- 2)(TGF-B superfamily receptor type I)(TSR-I) ACVR1B activin A receptor, type IB FXC01408 ¥40,000 FHC01408 ¥50,000 ACVR1C activin A receptor, type IC FXC09109M ¥50,000 FHC09109 ¥50,000 ACVRL1 activin A receptor type II-like 1, transcript variant 1 FXC28135M ¥50,000 FHC28135 ¥50,000 ADRBK1 adrenergic, beta, receptor kinase 1 FXC09648M ¥50,000 FHC09648 ¥50,000 ADRBK2 adrenergic, beta, receptor kinase 2 FXC27231M ¥50,000 FHC27231 ¥50,000 AKT1 v-akt murine thymoma viral oncogene homolog 1 FXC02215 ¥40,000 FHC02215 ¥50,000 AKT2 v-akt murine thymoma viral oncogene homolog 2 FXC26633 ¥40,000 FHC26633 ¥50,000 v-akt murine thymoma viral oncogene homolog 3 (protein AKT3 FXC02812 ¥40,000 FHC02812 ¥50,000 kinase B, gamma) ALK anaplastic lymphoma receptor tyrosine kinase FXC00337 ¥40,000 FHC00337 ¥50,000 A-Raf proto-oncogene serine/threonine-protein kinase (EC ARAF FXC08066 ¥40,000 FHC08066 ¥50,000 2.7.11.1)(A-raf-1)(Proto-oncogene
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Supplementary Data
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Dema and Faust Et Al., Suppl. Material 2020.02.03
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Gene Symbol Accession Alias/Prev Symbol Official Full Name AAK1 NM 014911.2 KIAA1048, Dkfzp686k16132 AP2 Associated Kinase 1
Gene Symbol Accession Alias/Prev Symbol Official Full Name AAK1 NM_014911.2 KIAA1048, DKFZp686K16132 AP2 associated kinase 1 (AAK1) AATK NM_001080395.2 AATYK, AATYK1, KIAA0641, LMR1, LMTK1, p35BP apoptosis-associated tyrosine kinase (AATK) ABL1 NM_007313.2 ABL, JTK7, c-ABL, p150 v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1) ABL2 NM_007314.3 ABLL, ARG v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (ABL2) ACVR1 NM_001105.2 ACVRLK2, SKR1, ALK2, ACVR1A activin A receptor ACVR1B NM_004302.3 ACVRLK4, ALK4, SKR2, ActRIB activin A receptor, type IB (ACVR1B) ACVR1C NM_145259.2 ACVRLK7, ALK7 activin A receptor, type IC (ACVR1C) ACVR2A NM_001616.3 ACVR2, ACTRII activin A receptor ACVR2B NM_001106.2 ActR-IIB activin A receptor ACVRL1 NM_000020.1 ACVRLK1, ORW2, HHT2, ALK1, HHT activin A receptor type II-like 1 (ACVRL1) ADCK1 NM_020421.2 FLJ39600 aarF domain containing kinase 1 (ADCK1) ADCK2 NM_052853.3 MGC20727 aarF domain containing kinase 2 (ADCK2) ADCK3 NM_020247.3 CABC1, COQ8, SCAR9 chaperone, ABC1 activity of bc1 complex like (S. pombe) (CABC1) ADCK4 NM_024876.3 aarF domain containing kinase 4 (ADCK4) ADCK5 NM_174922.3 FLJ35454 aarF domain containing kinase 5 (ADCK5) ADRBK1 NM_001619.2 GRK2, BARK1 adrenergic, beta, receptor kinase 1 (ADRBK1) ADRBK2 NM_005160.2 GRK3, BARK2 adrenergic, beta, receptor kinase 2 (ADRBK2) AKT1 NM_001014431.1 RAC, PKB, PRKBA, AKT v-akt murine thymoma viral oncogene homolog 1 (AKT1) AKT2 NM_001626.2 v-akt murine thymoma viral oncogene homolog 2 (AKT2) AKT3 NM_181690.1
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Anti-FES Antibody Catalog # ABO11162
10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 Anti-FES Antibody Catalog # ABO11162 Specification Anti-FES Antibody - Product Information Application WB Primary Accession P07332 Host Rabbit Reactivity Human Clonality Polyclonal Format Lyophilized Description Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Fes/Fps(FES) detection. Tested with WB in Human. Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml. Anti-FES antibody, ABO11162, Western blottingAll lanes: Anti FES (ABO11162) at 0.5ug/mlWB: HELA Whole Cell Lysate at Anti-FES Antibody - Additional Information 40ugPredicted bind size: 93KDObserved bind size: 93KD Gene ID 2242 Other Names Anti-FES Antibody - Background Tyrosine-protein kinase Fes/Fps, 2.7.10.2, Feline sarcoma/Fujinami avian sarcoma FES(feline sarcoma oncogene) is oncogene homolog, Proto-oncogene c-Fes, anÂ enzymeÂ that in humans is encoded by Proto-oncogene c-Fps, p93c-fes, FES, FPS theÂ FESÂ gene, also known as Proto-oncogene tyrosine-protein kinase Fes/Fps, Feline Calculated MW sarcoma/Fujinami avian sarcoma oncogene 93497 MW KDa homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes c-fes/fps Application Details protein, FPS, Oncogene FES, feline sarcoma Western blot, 0.1-0.5 µg/ml, Human<br> virus, FPS. This gene encodes the human cellular counterpart of a feline sarcoma Subcellular Localization retrovirus protein with transforming Cytoplasm, cytosol. Cytoplasm, capabilities. Non-onc intervening sequences cytoskeleton. Cell membrane; Peripheral were present in the human counterpart. The membrane protein; Cytoplasmic side. gene product has tyrosine-specific protein Cytoplasmic vesicle.
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Kinome Expression Profiling to Target New Therapeutic Avenues in Multiple Myeloma
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Mouse Oncogene Primer Library
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