2009-2010 Annual Report
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WORKING TOGETHER TO ADVANCE GENOMICS IN CANADA Abdallah Daar Peter Singer Aled Edwards Program Andrew Emili Andrew Macpherson Ontario Genomics Platform Affiliates Abdallah Daar Peter Singer Anthony Pawson Arturas Petronis Basil Arif Brenda Andrews Aled Edwards Andrew Emili Program Genomics Teaching Prize Summer Brent Zanke Cheryl Arrowsmith Chris Hogue Christian Burks Andrew Macpherson Anthony Pawson Research Fellowship Program Student Network Club Arturas Petronis Basil Arif Brenda Genome Pre-commercialization Business Development Fund Cynthia Guidos Daniel Figeys David MacLennan Gary Bader Geee! In Genome Tak Mak Canadian Barcode of Life Network Andrews Brent Zanke Cheryl Arrowsmith Quaid Morris Gilles Lajoie Jack Greenblatt James Woodgett Chris Hogue Christian Burks Cynthia Ontario Genomics Institute Annual Report 2010 Janet Rossant Jayne Danska Jeff Wrana John Coleman John Dick Guidos Daniel Figeys David MacLennan Celebrating 10 years of genomics leadership Gary Bader Quaid Morris Gilles Lajoie Katherine Siminovitch Kevin Kain Lap-Chee Tsui Lori Frappier Mark Jack Greenblatt James Woodgett Janet University of Guelph Genome Project The Hospital for Sick Children, Toronto Henkelman Mehrdad Hajibabaei Michael Rudnicki Paul Hebert Paul Rossant Jayne Danska Jeff Wrana John The Centre for Applied Genomics (TCAG) The Dynactome: Mapping Piunno Peter Durie Peter Liu Robert Hegele Scott Tanner Shana Kelley Coleman John Dick Katherine Siminovitch Spatio-Temporal Dynamic Systems in Humans Samuel Kevin Kain Lap-Chee Tsui Lori Frappier Lunenfeld Research Institute, Genomic Resource Core Facility Shawn Li Stephen Scherer Ted Sargent Tom Hudson Turlough Finan Ulrich Krull Mark Henkelman Mehrdad Hajibabaei Mount Sinai Hospital, Toronto U n i v e r s i t y o f W e s t e r n Xavier Estivill Database of Genomic Variants Barcode of Life Data Systems (BOLD) M i c h a e l Rudnicki Paul Hebert Paul Ontario, London Genome- Environment Interactions in Autism Chromosome Rearrangement Database Chromosome 7 Annotation Project Piunno Peter Durie Peter Liu Robert Type I Diabetes McMaster University Identification of Hegele Scott Tanner Shana Genetic Pathways that Regulate the Survival and Cystic Fibrosis Mutation Database Human Genome Segmental Duplication Database Kelley Shawn Li Stephen Development of Cancer and Cancer Stem Cells Non-Human Segmental Duplication Database StemBasse Structural Genomics Consortium Integrative Biology University of Toronto Quantum Dot Scherer Ted Sargent Tom Materials and Methods Toronto Yeast Interaction Database Toronto Yeast Pathway Database Hudson Turlough Finan Ulrich Diagnostics: Simultaneous Genomic and Proteomic Krull Xavier Estivill Database Profiling of Multiple Pathogens at Point-of-Care University DNA Barcoding Cancer stem cells Copy Number Varients (CNV) DVS Sciences Protein of Genomic Variants Barcode Health Network FIO Systems Corporation The Contribution Interaction Pathways Genomics and global health The Centre for Applied Genomics (TCAG) of Genetic Modulators of Disease Severity in Cystic of Life Data Systems (BOLD) Dynactome DyNeMo Yeast genetics Pre-commercialization Business Development Fund Chromosome Rearrangement Fibrosis to Other Diseases with Similarities of Clinical Database Chromosome 7 Phenotype Strengthening the Role of Genomics and Genomics Capacity Building Workshops Technology Days Science with Industry Workshops Annotation Project Cystic Global Health Structural and Functional Annotation of the Genomics Technology Seeding Program Ontario Genomics Platform Affiliates Program Human Genome for Disease Study Robarts Research Fibrosis Mutation Database Genomics Teaching Prize Summer Research Fellowship Program Student Network Human Genome Segmental Institute International Barcode of Life (iBOL) Duplication Database Non- Structural Genomics Consortium (SGC) – Phase II Club Genome Geee! In Genome Tak Mak Canadian Barcode Human Segmental Duplication International Regulome Consortium (IRC) Ottawa of Life Network University of Guelph Database StemBasse Structural Health Research Institute Automated Three-dimensional Hospital for Sick Children, Toronto Genomics Consortium Materials Phenotyping of Mouse Embryos Environmental and Methods Toronto Yeast Barcoding through Massively Parallelized Sequencing The Dynactome: Mapping Spatio- Interaction Database Toronto Massively Multiparametric Flow Cytometer Analyzer Temporal Dynamic Systems in Humans Yeast Pathway Database Multiplexed MicroRNA Detection on an Electronic Chip Proteomic Samuel Lunenfeld Research Institute DNA Barcoding Cancer stem Technologies for the Study of Rare Cells University of Ottawa cells Copy Number Varients Software Tools to Simplify Gene Function Prediction Technologies Mount Sinai Hospital,Toronto (CNV) DVS Sciences Protein for Methylome Studies Centre for Addiction and Mental Health University of Western Ontario, London Interaction Pathways Autism Bioproducts and Enzymes from Environmental Metagenomes (BEEM) Genome-Environment Interactions in Genomics and global health The Geosyntec Consultants Genomics for Crop Improvement: Agricultural Pest Type I Diabetes McMaster University Centre for Applied Genomics Management Development of Highly Active Anti-Leukemia Stem Cell (TCAG) Dynactome DyNeMo Therapy (HALT) Therapeutic Opportunities to Target Tumor Initiating Identification of Genetic Pathways Yeast genetics Genomics Cells in Solid Tumors Canadian Program on Genomics and Global that Regulate the Survival and Capacity Building Workshops Health Genetic Determinants of Human Health and Disease Development of Technology Days Science Annotation of Chromosome 7 Proteomics Technology with Industry Workshops Core Facility (PTCF) Genetic Determinants of Cancer and Cancer Genomics Technology Seeding Human Health and Disease Stem Cells Integrative Biology Quantum Dot Diagnostics PARTIAL GENE SEQUENCES DERIVED FROM: Page 7 Butterfly - Danaus plexippus pgm Gene OGI’S MISSION Page 9 Yeast - Saccharomyces cerevisiae strain S288C ARP4 gene Page 11 Cancer Stem Cell - Homo sapiens T-cell acute lymphocytic leukemia 1 (TAL1), USE WORLD-CLASS RESEARCH TO CREATE STRATEGIC GENOMICS RESOURCES Page 13 Genomics platform - TCAG: from the cystic fibrosis mutation database Page 15 Autism - Homo sapiens SHANK3 and multiple ankyrin repeat domains MaRS Centre, Heritage Building t. +1 416-977-9582 AND ACCELERATE ONTARIO’S DEVELOPMENT OF A GLOBALLY-COMPETITIVE Page 17 Mosquito - Anopheles gambiae AGAP007345-PA 101 College Street, Suite HL50 f. +1 416-977-8342 Toronto, Ontario www.OntarioGenomics.ca Page 19 Protein Interaction Mapping - Homo sapiens breast cancer 2, early onset (BRCA2) Canada M5G 1L7 [email protected] LIFE SCIENCES SECTOR. Page 21 Global Health - from HIV-1 isolate SE6954 from Uganda Page 23 Crop pest - Tribolium confusum β tubulin WORKING TOGETHER TO ADVANCE GENOMICS IN CANADA Abdallah Daar Peter Singer Aled Edwards Program Andrew Emili Andrew Macpherson Ontario Genomics Platform Affiliates Abdallah Daar Peter Singer Anthony Pawson Arturas Petronis Basil Arif Brenda Andrews Aled Edwards Andrew Emili Program Genomics Teaching Prize Summer Brent Zanke Cheryl Arrowsmith Chris Hogue Christian Burks Andrew Macpherson Anthony Pawson Research Fellowship Program Student Network Club Arturas Petronis Basil Arif Brenda Genome Pre-commercialization Business Development Fund Cynthia Guidos Daniel Figeys David MacLennan Gary Bader Geee! In Genome Tak Mak Canadian Barcode of Life Network Andrews Brent Zanke Cheryl Arrowsmith Quaid Morris Gilles Lajoie Jack Greenblatt James Woodgett Chris Hogue Christian Burks Cynthia Ontario Genomics Institute Annual Report 2010 Janet Rossant Jayne Danska Jeff Wrana John Coleman John Dick Guidos Daniel Figeys David MacLennan Celebrating 10 years of genomics leadership Gary Bader Quaid Morris Gilles Lajoie Katherine Siminovitch Kevin Kain Lap-Chee Tsui Lori Frappier Mark Jack Greenblatt James Woodgett Janet University of Guelph Genome Project The Hospital for Sick Children, Toronto Henkelman Mehrdad Hajibabaei Michael Rudnicki Paul Hebert Paul Rossant Jayne Danska Jeff Wrana John The Centre for Applied Genomics (TCAG) The Dynactome: Mapping Piunno Peter Durie Peter Liu Robert Hegele Scott Tanner Shana Kelley Coleman John Dick Katherine Siminovitch Spatio-Temporal Dynamic Systems in Humans Samuel Kevin Kain Lap-Chee Tsui Lori Frappier Lunenfeld Research Institute, Genomic Resource Core Facility Shawn Li Stephen Scherer Ted Sargent Tom Hudson Turlough Finan Ulrich Krull Mark Henkelman Mehrdad Hajibabaei Mount Sinai Hospital, Toronto U n i v e r s i t y o f W e s t e r n Xavier Estivill Database of Genomic Variants Barcode of Life Data Systems (BOLD) M i c h a e l Rudnicki Paul Hebert Paul Ontario, London Genome- Environment Interactions in Autism Chromosome Rearrangement Database Chromosome 7 Annotation Project Piunno Peter Durie Peter Liu Robert Type I Diabetes McMaster University Identification of Hegele Scott Tanner Shana Genetic Pathways that Regulate the Survival and Cystic Fibrosis Mutation Database Human Genome Segmental Duplication Database Kelley Shawn Li Stephen Development of Cancer and Cancer Stem Cells Non-Human Segmental Duplication Database StemBasse Structural Genomics Consortium Integrative Biology University of Toronto Quantum Dot Scherer Ted Sargent Tom Materials and Methods Toronto Yeast Interaction Database Toronto Yeast Pathway Database Hudson Turlough Finan Ulrich Diagnostics: Simultaneous Genomic and Proteomic Krull Xavier Estivill Database Profiling of Multiple Pathogens at Point-of-Care University