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'0> VIII. Appendix 'g =: 0.. Structures, systematic, trivial, generic and trade names of protein anabolic steroids ~. Structure Systematic name" Trivial and/or generic name Trade name Manufacturer L.T!'''..tosterQ!.le-deril1ed l!.rote~anabolic steroids 17 fi-Hydroxyandrost- Testosterone Geno-cristaux Gremy H 4-en-3-one Malestrone Kirk, N.Y. cOVo Orquisteron/Frosst (Columbia) Primotest Schering A.G. o 0 Oreton Schering -acetate Aceto-Sterandryl Roussel Aceto-Testoviron Schering A.G. Perandrone A ClBA -propionate Oreton Schering Perandren Ciba-Geigy Sterandryl Roussel Testoviron Schering Anertan Boehringer (M) Enarmon Takeda (Japan) -(3-p-hexyloxiphenyl)- Androdurin Leo, propionate (Helsingborg) -heptanoate (enanthate) Delatestryl Squibb Androtardyl Schering-Sepps Testoenant Geymonod -cycJopentyl propionate Depot testosterone Upjohn cypionate 4-Ch1oro-17 fi-hydroxy- Chlorotestosterone Steranabol Farmitalia androst-4-en-3-one -acetate Macrobin Teikoku ~Ol! Turinabol Jenapharm Turinabol inj. Jenapharm 0\ o 0 IV -capronate Macrobin-depot Teikoku -...J Cl 0\ Appendix (continued) tv 00 Structure Systematic namea Trivial and/or generic name Trade name Manufacturer 17 P-Hydroxy-17-methyl- Methyltestosterone Metandren Ciba androst-4-en-3-one Anertan Boehringer (M) Oreton Schering *OH Android Brown o ~ CH 3 9cx-Fluoro-llp,17P-dihydroxy- Fluoxymesterone Halotestin Upjohn 17-methylandrost-4-en-3-one Ultandren Ciba Androfluorene Midy 0£UOH Fluotestin Roter o ~ Orateston Hoechst CH 3 4,17 P-Dihydroxy-17-methyl- Oxymesterone, Oranabol Farmitalia androst -4-en -3-one 4-Hydroxymethyltestosterone Kabi Lipfa Q5DOIl May & Baker o ~ Sanaboral Ikapharm Theranabol Theraplix OH IIIX,17 P-Dihydroxy-17-methyl- lllX-Hydroxy- etsDoH androst-4-en-3-one methyltestosterone o ~ 17p-Hydroxy-17-methyl- 11-0xomethyltestosterone androst-4-ene-3,11-dione ct)BoH '0>- '0 (1) ::l o ~ 0- >;" Appendix (continued) Structure Systematic name" Trivial and/or generic name Trade name Manufacturer '0;..- '0 (1l CH 3 4-Chloro-17 fJ-hydroxy-17 -methyl- Chloromethyitestosterone Turinabol tab!. Jenapharm ::l q950H androst-4-en- 3-one ~ o ,-::; Cl CH 3 liX,7iX-Bis(acetylthio)- Thiomesterone Emdabol Merck A.G. ". OH 17 fJ-hydroxy-17-methyl- CH~ androst-4-en-3-one "'SCOCH o ~ 3 17 j3-Hydroxy-17-methyl- Methandrostenolone Dianabol Ciba androsta-l,4-dien-3-one Methandienone Abirol Takeda I-Dehydromethyltestosterone Geabol Gea mBoH Nabolin Eisai Nerobil Richter o ,-::; Vanabol Vitrum -cyclopentenyl ether Anabolicus Vister (gen.) Quinbolon 4-Chloro-17 j3-hydroxy- Chloro-l-dehydromethyl- Oral-Turinabol Jenapharm 17 -methylandrosta-l,4-dien- testosterone ~OH 3-one o ,-::; Cl CH 3 17 j3-Hydroxy-7iX, 17iX-dimethyl- Bolasterone, Myagen Upjohn ", OH androst-4-en-3-one Dimethyltestosterone Callusterone Methosarb Upjohn 0'1 oo2? N\0 0\ w Appendic (continued) 0 Structure Systematic name" Trivial and/or generic name Trade name Manufacturer II. J9-N ortestosterone-derived protein anabolic steroids 17[3-Hydroxyestr-4- 19-N ortestosterone Nerobolil Medimpex H en-3-one Nandrolone Nortestonate Upjohn oSDo -n-capronate Methybol-depot Mepha -propionate Norybol Serono o ~ Anabolicus-Serono Ausonia -phenyl propionate Activin Aristegui Durabol Pharmacia Durabolin Organon Nerobolil Richter Neutrosteron Organon -furylpropionate Demolon Mochida -hexahydrobenzoate Nor-Durandon Ferring -hexyloxyphenylpropionate Anadur Leo-Lundbeck -Iaurate Laurabolin Organon (Vet.) -undecylate Dynabolon Theramex -decanoate Abolon Benzon Deca-Durabol Pharmacia Deca-Durabolin Organon Eubolin Futerapica Nordecon IBSA Retabolil Richter -hemisuccinate Menidrabol Menarini -cyclohexylpropionate Fherbolico Fher Sanabolicum Sanabo -cyclopentylpropionate Sterocrinolo Orma Depo-N ortestonate Upjohn Pluropon Boehringer '0;I> '0 -4-methylbicyclo[2.2.2Joct- Syntex (1) 2-ene-I-carboxylate 0-::s ;;<. Appendix (continued) g'0>- Structure Systematic name" Trivial and/or generic name Trade name Manufacturer 0. :;;;" 4,17 fJ-Dihydroxyestr- Oxabolone Steranabol-depot Farmitalia 4-en-3-one 4-hydroxy-19-nortestosterone qSX50H -cycJopentylpropionate o .d OR 4-Chloro-17 fJ-hydroxyestr- Chloro-19-nortestosterone qSX50H 4-en-3-one -acetate Steranabol FarmitaJia o .d CI 17 fJ-Hydroxy-17-methyl- Methyl-19-nortestosterone Methalutin Syntex ~OH estr-4-en-3-one Orgasteron Organon o .d 17 fJ-Hydroxy-19-nor- N orethandrolone Nilevar Searle pregn-4-en-3-one Ethylnortestosterone Nor-Neutrormone ICI Pronabol Isis bH -propionate Solevar Byla oo13 .d 17fJ-Hydroxy-19-nor- Ethyldienolone ~bH pregna-4,9-dien-3-one a- o .d w 0'1 W Appendix (continued) N Structure Systematic name" Trivial and/or generic name Trade name Manufacturer HSC2 (dl)-17 {3-Hydroxy-13{3,17rx­ Norbolethone Genabol Wyeth C2Hs dieth ylgon A-en -3-one . OH (dl)-13-EthYI-17- ) ( hydroxy-18,19-dinor- 17rx-pregn-4-en-3-one o I I I. Androstane-derived protein anabolic steroids 3{3-Hydroxy-5rx-androstan- Epiandrosterone no* 17-one Isoandrosterone 17 {3-Hydroxy-5rx­ Androstanolone Anaboleen B.A.G. androstan -3-one Stanolone Uni Chemie Dihydrotestosterone Anabolex Lloyd-Hamol o&on Samil Androlone Orma Proteina Gremy Protona Gremy Apeton Fujisawa -valerian ate Apeton depot Fujisawa 3rx-Hydroxy-5rx­ Androsterone androstan-17 -one >­ 1I0cJ5rl g"0 0- ~. Appendix (continued) Structure Systematic namea Trivial and/or generic name Trade name Manufacturer > 17 P-Hydroxy-2ct-methyl- Drostanolone Drolban Lilly ] Q.. 5ct-androstan-3-one 2ct-Methylandrostanolone Masterone Recovdati ~. H3C ... Sarva *OH Syntex o : 2ct-Methyldihydrotestosterone Metorman Latino -propionate Mastizol Shionogi 17 P-Hydroxy-lct-methyl- Mesterolone Mestoran Schering 5ct-androstan-3-one (Denmark) asuOH Proviron Schering A.G. o : 5ct-Androstane-3p,17 P-diol- Androstanediol- Ectovis Vister o*OH 3-n-octyl-enol-ether 3-n-octyl-enol ether Ectovister Drovyssa \ . n-CSH7 CH3 17 p-Hydroxy-17 -methyl- Mestanolone Ermalon Roussel 5il-androstan-3-one Methylandrostanolone Androstalone Roussel *OH -enanthoyl-acetate N otandron-depot Boehringer (M) o .: CH3 17 P-Hydroxy-17-methyl- Oxymetholone Adroyd Parke-Davis ... OH 2-(hydroxy-methylene)- Sankyo 5ct-androstan-3-one Anadrol Shionogi Syntex HOCH~xX(5 Anadroyd Parke-Davis Anapolon ICI Anasterone Syntex Anasterona Latino Nastenon Cassenne w~ Protanabol Recordati Synasterobe Sarva 0\ w Appendix (continued) .j>. Structure Systematic namea Trivial and/or generic name Trade name Manufacturer IV Heterocyclic protein anabolic steroids 17-Methyl-51X-androstano- Stanozolol Winstrol Yamanouchi [3,2-c]-pyrazol-17 f3-ol Winthrop Zambon HC,20H Stromba Winthrop HN' \W : Tevabolin Teva 17-Methyl-51X-androstano- Androisoxazole Androxan Leo-Lundbeck [3,2-c]-isoxazol-17 f3-ol Neo-Ponden Serono Neo-Pondus Ausonia HC,20H 0' \N'" : CH 3 2',17-Dimethylandrost-5(10)- eno[3,2-dJ-thiazol-17f3-ol ?~url C~ :1 3-Azi-17-methyl-51X- Methyldiazirinol H androstan-17f3-ol NaOII " N : 17 f3-Hydroxy-21X, 17-dimethyl- Dimethazine Roxilon Richter 51X-androstan-3,3' -azine Dostalon Richter ( CH, '0:> j '0 (1) ~:nSXyH2 ::s0- ;;<" :» Appendix (continued) "0 "0 0 i:I Structure Systematic name' Trivial and/or generic name Trade name Manufacturer 0- :;;;. 17 f3-Hydroxy-17 -methyl- Oxandrolone Anavar Searle mEoH 2-oxa -SO(-androstan -3-one o : v. Miscellaneous structure protein anabolic steroids 17f3-Hydroxy-l-methyl- Methenolone Nibol Squibb SO(-androst-l-en-3-one Primobolan Schering A. G. H Primobolan-Acetate Schering A.G. JpDO -acetate -enanthate Primo bolan-Depot Schering A.G. CH3 17-Methyl-3-methylene-Sa:- androst-l-en-17f3-01 ~ca9=yH CH3 17-Methyl-androst-S- Methylandrostenediol Crestabolic Nutrition ene-3f3,17f3-diol Control Products H Methandriol Diandrin Astra HorO Megabion Teikoku Metilandrostendiol Schering A. G. Neosteron Organon Pharmacia Neutrormone lSI Notandren Boehringer (M) Protandren Ciba 0\ <.;.> Stenediol Organon Vl 0\~ Appendix (continucd) Structure Systematic namea Trivial and/or generic name Trade name Manufacturer -3-propionate Metilbisexovis Vister Methilbisexovister Drovyssa Metildiolo Orma -dipropionate Anabolin Rafa Metandiol Roussel -dienanthoylacetate N otandren-depot Boehringer (M) 3 p-H ydroxyandrost- Dehydroepiandrosterone Psicosterone ICI 5-en-17 -one Dehydroisoandrosterone Diandrone Organon lIoaSrl -acetate 17 -Chetovis Vister C2HS 19-N orpregn-4-en-17 p-ol Ethylestrenol Duraboral Organon Maxibolin Organon Orabolin Organon CJ500H Orgaboral Organon Durabolin-O Organon Orgabolin Organon 17IX-Oxo-D-homo-androsta- L1' -testololactone Teslac Squibb ~laOJO 1,4-diene-3,17-dione 1,2,3,4,4a,4b,7,9,lO,10a- ) OOJ~ ( decahydro-2-hydroxy-2, 4b-dimethyl-7-oxo-l­ phenanthrene propionic acid a Chemical Abstracts Systematic Name, Collective Subject Indices, Chemical Abstract. e. Prepared by ARNOLD, A., POTTS,G.O., and BEYLER,A.L. fQ.. ~. Author Index Page numbers in italics refer to bibliography Aakvaag,A., see Stromme, Adda,M. 581,599 Al brigh t, F., Parsons, W., S. B. 521,534 Addis, T., Lew, W. 121, 143 Bloomberg, E. 50,56,62,68 Abarbanei,A.R., see Rubinstein, Adler, P., see Poser, G. 547,618 Albright, F., Reifenstein, E. C. H.S. 73,152 Aebi, U., see Vassella, F. 561, 56,68 Abe,O., Herranen,A., 623 Albright, F., Smith,P. H., Fraser, Dorfman,R.L 197, 198,207 Aepli,R. 567,596,599 R. 167,177 Abe,O., see Rooks,W.H. Aegerter, E. A., see Shay, H. Albright, F., see Klinefelter, 197,209 201,202,209 H. F., Jr. 456,477 Abe,O., see Takatani,O. 193, Agafonowa,G.A., see Sinitzin, Albright, F., see Reifenstein, 210 P.D. 557,621 E.C.,Jr. 8,43,388,405425, Abeliuk,J., see Vargas,L. 78, Agapova, E. N., Tkachenko, 426, 427, 430, 434, 436, 438 108, 129, 132,153 A. M., Krutovskaya, O. V. Aleksandriva, L. M., see Tirkina, Abraham;R., Staudinger,Hj. 550,599 T. N. 571, 622 295,298,351 Agerty,H.A., see Seitchik,J. N. Alessi, E., see Bonelli, M. Abrahamson,M., see 449,481 175,178 Muldowney,F.P. 435,438 Ahlendorf, W., Kob,D. 581, Alexanian,R. 488,494 Abramowicz,M., see 599 Alexanian,R., see Adamson, Bettmann,H.K. 425,436, Ahn,C.S., see Rosenberg, LN. J. W. 488,494 452,473 467,480 Alfert, M., see Bern. H. A. Abritta,J. 465,472 Ahren,K., Arvil\,A., Hjalmar­ 118, 144 Aceto,M.D., see Watzman,N. son,A. 98,143 Alfin-Slater,R.
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    The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth Daniela Roell, Aria Baniahmad To cite this version: Daniela Roell, Aria Baniahmad. The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth. Molec- ular and Cellular Endocrinology, Elsevier, 2010, 332 (1-2), pp.1. 10.1016/j.mce.2010.09.013. hal- 00654968 HAL Id: hal-00654968 https://hal.archives-ouvertes.fr/hal-00654968 Submitted on 24 Dec 2011 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Accepted Manuscript Title: The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth Authors: Daniela Roell, Aria Baniahmad PII: S0303-7207(10)00474-0 DOI: doi:10.1016/j.mce.2010.09.013 Reference: MCE 7644 To appear in: Molecular and Cellular Endocrinology Received date: 29-6-2010 Revised date: 3-9-2010 Accepted date: 27-9-2010 Please cite this article as: Roell, D., Baniahmad, A., The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth, Molecular and Cellular Endocrinology (2010), doi:10.1016/j.mce.2010.09.013 This is a PDF file of an unedited manuscript that has been accepted for publication.
  • Effects of Zilpaterol and Melengestrol Acetate On

    Effects of Zilpaterol and Melengestrol Acetate On

    EFFECTS OF ZILPATEROL AND MELENGESTROL ACETATE ON BOVINE SKELETAL MUSCLE GROWTH AND DEVELOPMENT by ERIN KATHRYN SISSOM B.S., California State University, Fresno, 2002 M.S., Kansas State University, 2004 AN ABSTRACT OF A DISSERTATION submitted in partial fulfillment of the requirements for the degree DOCTOR OF PHILOSOPHY Department of Animal Sciences and Industry College of Agriculture KANSAS STATE UNIVERSITY Manhattan, Kansas 2009 Abstract Zilpaterol (ZIL) is a β-adrenergic receptor (β-AR) agonist that has been recently approved for use in feedlot cattle to improve production efficiencies and animal performance. One of the mechanisms through which this occurs is increased skeletal muscle growth. Therefore, two experiments were conducted to determine the effects of ZIL both in vivo and in vitro . In the first experiment, ZIL addition to bovine satellite cells resulted in a tendency to increase IGF-I mRNA and increased myosin heavy chain IIA (MHC) mRNA with 0.001 µ M and decreased MHC mRNA with 0.01 and 10 µ M. There were no effects of ZIL on protein synthesis or degradation. In myoblast cultures, there was a decrease in all three β-AR mRNA, and this was also reported in western blot analysis with a reduction in β2-AR expression due to ZIL treatment. In myotubes, there was an increase in β2-AR protein expression. In the second and third experiment, ZIL improved performance and carcass characteristics of feedlot steers and heifers. Additionally, ZIL decreased MHC IIA mRNA in semimembranosus muscle tissue collected from both steers and heifers. An additional part of the third study was conducted to determine the effects of melengestrol acetate (MGA) on bovine satellite cell and semimembranosus muscle gene expression.
  • Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017

    Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017

    Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 BR 111 / 2017 The Minister responsible for health, in exercise of the power conferred by section 48A(1) of the Pharmacy and Poisons Act 1979, makes the following Order: Citation 1 This Order may be cited as the Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017. Repeals and replaces the Third and Fourth Schedule of the Pharmacy and Poisons Act 1979 2 The Third and Fourth Schedules to the Pharmacy and Poisons Act 1979 are repealed and replaced with— “THIRD SCHEDULE (Sections 25(6); 27(1))) DRUGS OBTAINABLE ONLY ON PRESCRIPTION EXCEPT WHERE SPECIFIED IN THE FOURTH SCHEDULE (PART I AND PART II) Note: The following annotations used in this Schedule have the following meanings: md (maximum dose) i.e. the maximum quantity of the substance contained in the amount of a medicinal product which is recommended to be taken or administered at any one time. 1 PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 mdd (maximum daily dose) i.e. the maximum quantity of the substance that is contained in the amount of a medicinal product which is recommended to be taken or administered in any period of 24 hours. mg milligram ms (maximum strength) i.e. either or, if so specified, both of the following: (a) the maximum quantity of the substance by weight or volume that is contained in the dosage unit of a medicinal product; or (b) the maximum percentage of the substance contained in a medicinal product calculated in terms of w/w, w/v, v/w, or v/v, as appropriate.