Part I Officers in Institutions Placed Under the Supervision of the General Board
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ANNUAL REVIEW 1 October 2005–30 September
WELLCOME TRUST ANNUAL REVIEW 1 October 2005–30 September 2006 ANNUAL REVIEW 2006 The Wellcome Trust is the largest charity in the UK and the second largest medical research charity in the world. It funds innovative biomedical research, in the UK and internationally, spending around £500 million each year to support the brightest scientists with the best ideas. The Wellcome Trust supports public debate about biomedical research and its impact on health and wellbeing. www.wellcome.ac.uk THE WELLCOME TRUST The Wellcome Trust is the largest charity in the UK and the second largest medical research charity in the world. 123 CONTENTS BOARD OF GOVERNORS 2 Director’s statement William Castell 4 Advancing knowledge Chairman 16 Using knowledge Martin Bobrow Deputy Chairman 24 Engaging society Adrian Bird 30 Developing people Leszek Borysiewicz 36 Facilitating research Patricia Hodgson 40 Developing our organisation Richard Hynes 41 Wellcome Trust 2005/06 Ronald Plasterk 42 Financial summary 2005/06 Alastair Ross Goobey 44 Funding developments 2005/06 Peter Smith 46 Streams funding 2005/06 Jean Thomas 48 Technology Transfer Edward Walker-Arnott 49 Wellcome Trust Genome Campus As at January 2007 50 Public Engagement 51 Library and information resources 52 Advisory committees Images 1 Surface of the gut. 3 Zebrafish. 5 Cells in a developing This Annual Review covers the 2 Young children in 4 A scene from Y fruit fly. Wellcome Trust’s financial year, from Kenya. Touring’s Every Breath. 6 Data management at the Sanger Institute. 1 October 2005 to 30 September 2006. CONTENTS 1 45 6 EXECUTIVE BOARD MAKING A DIFFERENCE Developing people: To foster a Mark Walport The Wellcome Trust’s mission is research community and individual Director to foster and promote research with researchers who can contribute to the advancement and use of knowledge Ted Bianco the aim of improving human and Director of Technology Transfer animal health. -
Is the Universe Expanding?: an Historical and Philosophical Perspective for Cosmologists Starting Anew
Western Michigan University ScholarWorks at WMU Master's Theses Graduate College 6-1996 Is the Universe Expanding?: An Historical and Philosophical Perspective for Cosmologists Starting Anew David A. Vlosak Follow this and additional works at: https://scholarworks.wmich.edu/masters_theses Part of the Cosmology, Relativity, and Gravity Commons Recommended Citation Vlosak, David A., "Is the Universe Expanding?: An Historical and Philosophical Perspective for Cosmologists Starting Anew" (1996). Master's Theses. 3474. https://scholarworks.wmich.edu/masters_theses/3474 This Masters Thesis-Open Access is brought to you for free and open access by the Graduate College at ScholarWorks at WMU. It has been accepted for inclusion in Master's Theses by an authorized administrator of ScholarWorks at WMU. For more information, please contact [email protected]. IS THEUN IVERSE EXPANDING?: AN HISTORICAL AND PHILOSOPHICAL PERSPECTIVE FOR COSMOLOGISTS STAR TING ANEW by David A Vlasak A Thesis Submitted to the Faculty of The Graduate College in partial fulfillment of the requirements forthe Degree of Master of Arts Department of Philosophy Western Michigan University Kalamazoo, Michigan June 1996 IS THE UNIVERSE EXPANDING?: AN HISTORICAL AND PHILOSOPHICAL PERSPECTIVE FOR COSMOLOGISTS STARTING ANEW David A Vlasak, M.A. Western Michigan University, 1996 This study addresses the problem of how scientists ought to go about resolving the current crisis in big bang cosmology. Although this problem can be addressed by scientists themselves at the level of their own practice, this study addresses it at the meta level by using the resources offered by philosophy of science. There are two ways to resolve the current crisis. -
Nhbs Annual New and Forthcoming Titles Issue: 2000 Complete January 2001 [email protected] +44 (0)1803 865913
nhbs annual new and forthcoming titles Issue: 2000 complete January 2001 [email protected] +44 (0)1803 865913 The NHBS Monthly Catalogue in a complete yearly edition Zoology: Mammals Birds Welcome to the Complete 2000 edition of the NHBS Monthly Catalogue, the ultimate Reptiles & Amphibians buyer's guide to new and forthcoming titles in natural history, conservation and the Fishes environment. With 300-400 new titles sourced every month from publishers and research organisations around the world, the catalogue provides key bibliographic data Invertebrates plus convenient hyperlinks to more complete information and nhbs.com online Palaeontology shopping - an invaluable resource. Each month's catalogue is sent out as an HTML Marine & Freshwater Biology email to registered subscribers (a plain text version is available on request). It is also General Natural History available online, and offered as a PDF download. Regional & Travel Please see our info page for more details, also our standard terms and conditions. Botany & Plant Science Prices are correct at the time of publication, please check www.nhbs.com for the Animal & General Biology latest prices. Evolutionary Biology Ecology Habitats & Ecosystems Conservation & Biodiversity Environmental Science Physical Sciences Sustainable Development Data Analysis Reference Mammals Activity Patterns in Small Mammals 318 pages | 59 figs, 11 tabs | Springer An Ecological Approach Hbk | 2000 | 354059244X | #109391A | Edited by S Halle and NC Stenseth £100.00 BUY Links chronobiology with behavioural and evolutionary ecology, drawing on research on mammals ranging from mongooses and civets to weasels, martens and shrews. .... African Rhino 92 pages | B/w photos, figs, tabs | IUCN Status Survey and Conservation Action Plan Pbk | 1999 | 2831705029 | #106031A | Richard Emslie and Martin Brooks £15.00 BUY Action plan aimed at donors, government and non-government organisations, and all those involved in rhino conservation. -
Risk Bounds for Classification and Regression Rules That Interpolate
Overfitting or perfect fitting? Risk bounds for classification and regression rules that interpolate Mikhail Belkin Daniel Hsu Partha P. Mitra The Ohio State University Columbia University Cold Spring Harbor Laboratory Abstract Many modern machine learning models are trained to achieve zero or near-zero training error in order to obtain near-optimal (but non-zero) test error. This phe- nomenon of strong generalization performance for “overfitted” / interpolated clas- sifiers appears to be ubiquitous in high-dimensional data, having been observed in deep networks, kernel machines, boosting and random forests. Their performance is consistently robust even when the data contain large amounts of label noise. Very little theory is available to explain these observations. The vast majority of theoretical analyses of generalization allows for interpolation only when there is little or no label noise. This paper takes a step toward a theoretical foundation for interpolated classifiers by analyzing local interpolating schemes, including geometric simplicial interpolation algorithm and singularly weighted k-nearest neighbor schemes. Consistency or near-consistency is proved for these schemes in classification and regression problems. Moreover, the nearest neighbor schemes exhibit optimal rates under some standard statistical assumptions. Finally, this paper suggests a way to explain the phenomenon of adversarial ex- amples, which are seemingly ubiquitous in modern machine learning, and also discusses some connections to kernel machines and random forests in the interpo- lated regime. 1 Introduction The central problem of supervised inference is to predict labels of unseen data points from a set of labeled training data. The literature on this subject is vast, ranging from classical parametric and non-parametric statistics [48, 49] to more recent machine learning methods, such as kernel machines [39], boosting [36], random forests [15], and deep neural networks [25]. -
Functional Effects Detailed Research Plan
GeCIP Detailed Research Plan Form Background The Genomics England Clinical Interpretation Partnership (GeCIP) brings together researchers, clinicians and trainees from both academia and the NHS to analyse, refine and make new discoveries from the data from the 100,000 Genomes Project. The aims of the partnerships are: 1. To optimise: • clinical data and sample collection • clinical reporting • data validation and interpretation. 2. To improve understanding of the implications of genomic findings and improve the accuracy and reliability of information fed back to patients. To add to knowledge of the genetic basis of disease. 3. To provide a sustainable thriving training environment. The initial wave of GeCIP domains was announced in June 2015 following a first round of applications in January 2015. On the 18th June 2015 we invited the inaugurated GeCIP domains to develop more detailed research plans working closely with Genomics England. These will be used to ensure that the plans are complimentary and add real value across the GeCIP portfolio and address the aims and objectives of the 100,000 Genomes Project. They will be shared with the MRC, Wellcome Trust, NIHR and Cancer Research UK as existing members of the GeCIP Board to give advance warning and manage funding requests to maximise the funds available to each domain. However, formal applications will then be required to be submitted to individual funders. They will allow Genomics England to plan shared core analyses and the required research and computing infrastructure to support the proposed research. They will also form the basis of assessment by the Project’s Access Review Committee, to permit access to data. -
Mothers in Science
The aim of this book is to illustrate, graphically, that it is perfectly possible to combine a successful and fulfilling career in research science with motherhood, and that there are no rules about how to do this. On each page you will find a timeline showing on one side, the career path of a research group leader in academic science, and on the other side, important events in her family life. Each contributor has also provided a brief text about their research and about how they have combined their career and family commitments. This project was funded by a Rosalind Franklin Award from the Royal Society 1 Foreword It is well known that women are under-represented in careers in These rules are part of a much wider mythology among scientists of science. In academia, considerable attention has been focused on the both genders at the PhD and post-doctoral stages in their careers. paucity of women at lecturer level, and the even more lamentable The myths bubble up from the combination of two aspects of the state of affairs at more senior levels. The academic career path has academic science environment. First, a quick look at the numbers a long apprenticeship. Typically there is an undergraduate degree, immediately shows that there are far fewer lectureship positions followed by a PhD, then some post-doctoral research contracts and than qualified candidates to fill them. Second, the mentors of early research fellowships, and then finally a more stable lectureship or career researchers are academic scientists who have successfully permanent research leader position, with promotion on up the made the transition to lectureships and beyond. -
Female Fellows of the Royal Society
Female Fellows of the Royal Society Professor Jan Anderson FRS [1996] Professor Ruth Lynden-Bell FRS [2006] Professor Judith Armitage FRS [2013] Dr Mary Lyon FRS [1973] Professor Frances Ashcroft FMedSci FRS [1999] Professor Georgina Mace CBE FRS [2002] Professor Gillian Bates FMedSci FRS [2007] Professor Trudy Mackay FRS [2006] Professor Jean Beggs CBE FRS [1998] Professor Enid MacRobbie FRS [1991] Dame Jocelyn Bell Burnell DBE FRS [2003] Dr Philippa Marrack FMedSci FRS [1997] Dame Valerie Beral DBE FMedSci FRS [2006] Professor Dusa McDuff FRS [1994] Dr Mariann Bienz FMedSci FRS [2003] Professor Angela McLean FRS [2009] Professor Elizabeth Blackburn AC FRS [1992] Professor Anne Mills FMedSci FRS [2013] Professor Andrea Brand FMedSci FRS [2010] Professor Brenda Milner CC FRS [1979] Professor Eleanor Burbidge FRS [1964] Dr Anne O'Garra FMedSci FRS [2008] Professor Eleanor Campbell FRS [2010] Dame Bridget Ogilvie AC DBE FMedSci FRS [2003] Professor Doreen Cantrell FMedSci FRS [2011] Baroness Onora O'Neill * CBE FBA FMedSci FRS [2007] Professor Lorna Casselton CBE FRS [1999] Dame Linda Partridge DBE FMedSci FRS [1996] Professor Deborah Charlesworth FRS [2005] Dr Barbara Pearse FRS [1988] Professor Jennifer Clack FRS [2009] Professor Fiona Powrie FRS [2011] Professor Nicola Clayton FRS [2010] Professor Susan Rees FRS [2002] Professor Suzanne Cory AC FRS [1992] Professor Daniela Rhodes FRS [2007] Dame Kay Davies DBE FMedSci FRS [2003] Professor Elizabeth Robertson FRS [2003] Professor Caroline Dean OBE FRS [2004] Dame Carol Robinson DBE FMedSci -
Probabilistic Circuits: Representations, Inference, Learning and Theory
Inference Probabilistic Representations Learning Circuits Theory Antonio Vergari YooJung Choi University of California, Los Angeles University of California, Los Angeles Robert Peharz Guy Van den Broeck TU Eindhoven University of California, Los Angeles January 7th, 2021 - IJCAI-PRICAI 2020 Fully factorized NaiveBayes AndOrGraphs PDGs Trees PSDDs CNets LTMs SPNs NADEs Thin Junction Trees ACs MADEs MAFs VAEs DPPs FVSBNs TACs IAFs NAFs RAEs Mixtures BNs NICE FGs GANs RealNVP MNs The Alphabet Soup of probabilistic models 2/153 Fully factorized NaiveBayes AndOrGraphs PDGs Trees PSDDs CNets LTMs SPNs NADEs Thin Junction Trees ACs MADEs MAFs VAEs DPPs FVSBNs TACs IAFs NAFs RAEs Mixtures BNs NICE FGs GANs RealNVP MNs Intractable and tractable models 3/153 Fully factorized NaiveBayes AndOrGraphs PDGs Trees PSDDs CNets LTMs SPNs NADEs Thin Junction Trees ACs MADEs MAFs VAEs DPPs FVSBNs TACs IAFs NAFs RAEs Mixtures BNs NICE FGs GANs RealNVP MNs tractability is a spectrum 4/153 Fully factorized NaiveBayes AndOrGraphs PDGs Trees PSDDs CNets LTMs SPNs NADEs Thin Junction Trees ACs MADEs MAFs VAEs DPPs FVSBNs TACs IAFs NAFs RAEs Mixtures BNs NICE FGs GANs RealNVP MNs Expressive models without compromises 5/153 Fully factorized NaiveBayes AndOrGraphs PDGs Trees PSDDs CNets LTMs SPNs NADEs Thin Junction Trees ACs MADEs MAFs VAEs DPPs FVSBNs TACs IAFs NAFs RAEs Mixtures BNs NICE FGs GANs RealNVP MNs a unifying framework for tractable models 6/153 Why tractable inference? or expressiveness vs tractability 7/153 Why tractable inference? or expressiveness -
Cambridge University Reporter No 6611, Wednesday 17 March 2021
CAMBRIDGE UNIVERSITY REPORTER No 6611 Wednesday 17 March 2021 Vol cli No 23 CONTENTS Notices Obituaries Calendar 431 Obituary Notice 437 Discussion on Tuesday, 23 March 2021 431 Graces Honorary Degree Congregation on Grace submitted to the Regent House on Wednesday, 23 June 2021: Cancellation 431 17 March 2021 437 Sermon at the Commemoration of John Mere: Postponement 431 End of the Official Part of the ‘Reporter’ Election to the Board of Scrutiny 431 Report of Discussion: 9 March 2021 Awards, etc. Remarks on the Report of the Council on Thomas Mulvey Egyptology Fund, 2021 431 recognition of the merger of Cambridge Events, courses, etc. University Press and Cambridge Assessment Announcement of lectures, seminars, etc. 432 in the University’s Statutes and Ordinances 438 No remarks on the Report of the General Notices by Faculty Boards, etc. Board on the establishment of a Professorship 440 History and Modern Languages Tripos, 2020–21 432 Linguistics Tripos, 2020–21 434 College Notices Elections 441 Modern and Medieval Languages Tripos, 2020–21 435 PUBLISHED BY AUTHORITY 431 CAMBRIDGE UNIVERSITY REPORTER 17 March 2021 NOTICES Calendar 19 March, Friday. Full Term ends. 23 March, Tuesday. Discussion via videoconference at 2 p.m. (see below). 24 March, Wednesday. Last issue of the Reporter in the Lent Term. 25 March, Thursday. Lent Term ends. 27 March, Saturday. Congregation of the Regent House via videoconference at 11 a.m. 17 April, Saturday. Easter Term begins. 21 April, Wednesday. First issue of the Reporter in the Easter Term. Discussion on Tuesday, 23 March 2021 The Vice-Chancellor invites those qualified under the regulations for Discussions (Statutes and Ordinances, p. -
Biology, Bioinformatics, Bioengineering, Biophysics, Biostatistics, Neuroscience, Medicine, Ophthalmology, and Dentistry
Biology, Bioinformatics, Bioengineering, Biophysics, Biostatistics, Neuroscience, Medicine, Ophthalmology, and Dentistry This section contains links to textbooks, books, and articles in digital libraries of several publishers (Springer, Elsevier, Wiley, etc.). Most links will work without login on any campus (or remotely using the institution’s VPN) where the institution (company) subscribes to those digital libraries. For De Gruyter and the associated university presses (Chicago, Columbia, Harvard, Princeton, Yale, etc.) you may have to go through your institution’s library portal first. A red title indicates an excellent item, and a blue title indicates a very good (often introductory) item. A purple year of publication is a warning sign. Titles of Open Access (free access) items are colored green. The library is being converted to conform to the university virtual library model that I developed. This section of the library was updated on 06 September 2021. Professor Joseph Vaisman Computer Science and Engineering Department NYU Tandon School of Engineering This section (and the library as a whole) is a free resource published under Attribution-NonCommercial-NoDerivatives 4.0 International license: You can share – copy and redistribute the material in any medium or format under the following terms: Attribution, NonCommercial, and NoDerivatives. https://creativecommons.org/licenses/by-nc-nd/4.0/ Copyright 2021 Joseph Vaisman Table of Contents Food for Thought Biographies Biology Books Articles Web John Tyler Bonner Morphogenesis Evolution -
Anne-Ruxandra Carvunis
Des protéines et de leurs interactions aux principes évolutifs des systèmes biologiques Anne-Ruxandra Carvunis To cite this version: Anne-Ruxandra Carvunis. Des protéines et de leurs interactions aux principes évolutifs des sys- tèmes biologiques. Médecine humaine et pathologie. Université de Grenoble, 2011. Français. NNT : 2011GRENS001. tel-00586614 HAL Id: tel-00586614 https://tel.archives-ouvertes.fr/tel-00586614 Submitted on 18 Apr 2011 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. THÈSE Pour obtenir le grade de DOCTEUR DE L’UNIVERSITÉ DE GRENOBLE Spécialité : MODELES, METHODES ET ALGORITHMES EN BIOLOGIE, SANTE ET ENVIRONNEMENT Arrêté ministériel : 7 août 2006 Présentée par Anne-Ruxandra CARVUNIS Thèse dirigée par Laurent TRILLING et codirigée par Nicolas THIERRY-MIEG et Marc VIDAL préparée au sein du Laboratoire du Professeur Marc Vidal et du laboratoire Techniques de l’Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications de Grenoble dans l’Ecole Doctorale Ingénierie pour la Santé, la Cognition et l’Environnement -
University of Cambridge Department of Veterinary Medicine Self
University of Cambridge Department of Veterinary Medicine Self-Evaluation Report Prepared for the joint visit of The Royal College of Veterinary Surgeons and The European Association of Establishments for Veterinary Education 1 List of Visitors Professor Susan Rhind University of Edinburgh, Chair Mr David Wadsworth RCVS Dr Katharina Stärk Spallek RCVS Professor Laslo Fodor EAEVE Dr Pierre Lekeux EAEVE Co-ordinator Professor John Elmerdahl EAEVE Professor Norman Williamson Australasian Veterinary Boards Council Miss Hannelore De Porte EAEVE-nominated student Mrs Clare Tapsfield-Wright RCVS observer Professor Vinny Naidoo South African Veterinary Council observer Mrs Freda Andrews RCVS staff Mrs Christine Warman RCVS staff 2 CONTENTS List of Visitors ............................................................................................................. 2 INTRODUCTION ........................................................................................................ 5 CHAPTER 1 OBJECTIVES ..................................................................................... 11 1.1 Factual information and overall objectives ................................................... 11 1.2 Comments ................................................................................................... 15 1.3 Suggestions ................................................................................................. 16 CHAPTER 2 ORGANISATION ................................................................................ 17 2.1 Factual information