Sample test questions

Krok 2 Pharmacy

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Фармацевтична хiмiя 2

1. An analyst of a chemical laboratory A. Ammonium oxalate had received a glucose substance for B. Magnesium sulfate analysis. To check its quality he used a C. Potassium chloride polarimeter. The analyst measured: D. Sodium nitrite E. Ammonium molybdate A. Angle of rotation B. Refractive index 7. Optical rotation angle of substances is C. Optical density determined under the temperature of 20oC, D. Melting point in 1-decimeter-thick layer, with wavelength E. Specificgravity of sodium spectrum D-lines (λ = 589.3 nm), and is calculated with reference to a solution 2. The analytical laboratory received containing 1 g of the substance per ml. It is calcium chloride. What volumetric called: solution should be used for quantitative determination of this medicinal substance? A. Specific optical rotation B. Optical density A. Sodium edetate C. Refractive index B. Potassium bromate D. Relative density C. Hydrochloric acid E. Distribution coefficient D. Potassium permanganate E. Sodium hydroxide 8. Which of the following antibiotics can be identified by means of maltol test? 3. An analytical chemist of a central industrial laboratory performs quantitative A. Streptomycin sulfate determination of penicillin sum in B. Doxycycline hydrochloride benzylpenicillin sodium salt by means of C. Amoxicillin iodometric method. What indicator is used? D. Lincomycin hydrochloride E. Kanamycin monosulfate A. Starch B. Phenolphthalein 9. A pharmaceutical analyst identifies C. Potassium chromate the substance of potassium acetate. What D. Methyl orange reagent confirms the presence of potassium E. Methyl red cation in the substance? 4. Paracetamol substance has been sent A. Tartaric acid for analysis. Reaction with the solution of B. Sodium hydroxide iron (III) chloride resilted in the blue-violet C. Potassium permanganate coloring. This indicates the presence of: D. Iron (III) chloride E. Zinc oxide A. Phenolic hydroxyl B. Aldehyde group 10. An analytical chemist performs the C. Keto group qualitative assessment of mercury (II) D. Ester group chloride. What method is recommended by E. Alcoholic hydroxyl the State Pharmacopoeia of Ukraine for quantitative assessment in this case? 5. An analytical laboratory has received a procaine hydrochloride substance A. Complexometric titration for analysis. According to the State B. Nitritometric titration Pharmacopoeia of Ukraine limit content of C. Bromatometry heavy metals should be determined with the D. Alkalimetry following reagent: E. Acidimetry A. Thioacetamide 11. An analytical chemist investigates a B. Methoxyphenylacetic acid 3% hydrogen solution. What reagent is C. Hypophosphite recommended by the State Pharmacopoeia D. Aminomethyl alizarin acetic acid of Ukraine for identification of this E. Sulfomolybdenum substance? 6. Chloride of lime is identified by calcium A. Potassium chromate cations after boiling with acetic acid in order B. Sodium chloride to eliminate active chlorine. What reagent is C. Magnesium sulfate used? D. Calcium chloride E. Zinc oxide 12. Benzoic acid is known to have antiseptic properties. Toidentify this acid the following should be used: Фармацевтична хiмiя 3

A. Glutaconic A. FeCl3 B. Gluconic B. [NH4]2C2O4 C. Glutamic C. K2[HgI4] D. Glyoxylic D. K2CrO4 E. Hexanic E. KMnO4 18. What method is recommended by 13. An analytical chemist analyses the the State Pharmacopoeia of Ukraine for substance of racemic menthol according to quantitative determination of potassium the State Pharmacopoeia of Ukraine. To chloride substance that is used in treatment identify the drug and determine its purity he of hypokalemia? measures optical rotation that should occur within the interval: A. Argentometry B. Bromatometry A. From +0.2o to -0.2o C. Iodometry B. From -48o to -51o D. Cerimetry C. From +50o to +56o E. Polarimetry D. From +10o to +13o E. From -102o to -105o 19. During limit test for aluminium admixture, the State Pharmacopoeia of 14. Presence of phenolic hydroxyl in the Ukraine recommends to use the following structure of pyridoxine hydrochloride can solution as the basic reagent: be confirmed by application of the following solution: A. Hydroxyquinoline B. Sodium tetraphenylborate A. Iron (III) cloride C. Thioglycolic acid B. Potassium permanganate D. Sodium hypophosphite C. Sodium sulfate E. Barium chloride D. Silver nitrate E. Sodium nitrite 20. Presence of nitrate radical in metronidazole structure can be confirmed 15. An analytical chemist can quantitatively by reduction of nitrate radical to amino determine the thiamine bromide content in group with production of: powders by means of: A. Azo dye A. Alkalimetry B. Indophenol B. Nitritometric titration C. Thiochrome C. Bromometry D. Iodoform D. Permanganatometry E. Murexide E. Complexometric titration 21. Xycaine quantitative content can be 16. Quantitative content of theophylline can determined by means of argentometry (back be determined by alkalimetric titration of titration). What indicator is required by this nitric acid that is quantitatively obtained as method? the result of the following theophylline salt production: A. Iron (III) ammonium sulphate B. Sodium eosinate A. Silver C. Bromphenol blue B. Potassium D. Starch C. Sodium E. Potassium chromate D. Ammonium E. Lithium 22. An analytical chemist performs quantitative analysis of isoniazid by means 17. In the process of isoniazid identification of direct bromatometry with volumetric a pharmacy analyst thoroughly boiled the solutions of potassium bromate, potassium substance with 2,4-dinitrochlorobenzene. bromide, hydrochloric acid and methyl red The substance turned yellow. After adding as an indicator. This method is based on the alkaline solution the substance turned first following reaction: violet and then brownish-red. As the result of this reaction the following aldehyde derivative is produced: Фармацевтична хiмiя 4

A. Oxidation of the hydrazine group with reagent. If these admixtures are present the bromine substance colors: B. Reduction of the hydrazine residue with bromine A. Red C. Oxidation of the hydrazine residue with B. Blue potassium bromide C. Green D. Opening of the pyridine ring D. Turquoise E. Bromination of the pyridine ring E. White 23. The main method of quantitative 29. The analyst determines quantitative determination of corticosteroids is: content of sodium benzoate by means of acidimetry in non-aqueous medium A. Spectrophotometry according to the State Pharmacopoeia of B. Potentiometry Ukraine. What reagent is used as a solvent C. Cerimetry in this case? D. Argentometry E. Acidimetry A. Anhydrous acetic acid B. Pyridine 24. According to the State Pharmacopoeia C. Concentrated sulfuric acid of Ukraine, an analytical chemist D. Dimethyl formamide determines quantitative content of E. Sulfanilic acid potassium acetate by means of acidimetry in non-aqueous medium. Name the volumetric 30. What antibiotic has beta-lactam cycle in solution in this case: its structure? A. Perchloric acid A. Benzylpenicillin potassium salt B. Iodine B. Doxycycline hyclate C. Potassium bromate C. Chloramphenicol D. Sodium hydroxide D. Streptomycin sulfate E. Sodium nitrite E. Lincomycin hydrochloride 25. The chemical name of 2,2- 31. The chemical name of 2-benzyl-1H- (diphenylmethoxy)-N,N-dimethyl-ethanamine benzimidazole hydrochloride corresponds hydrochloride corresponds with the with the following medicinal substance: following medicinal substance: A. Dibazol (Bendazolum) A. Diphenhydramine hydrochloride B. Omeprazole B. Ethylmorphine hydrochloride C. Indometacin C. Lidocaine hydrochloride D. Phenazepam D. Ciprofloxacin hydrochloride E. Vicasol (Menadione) E. Papaverine hydrochloride 32. Identification of potassium iodide 26. An analytical chemist should use the requires performing an oxidation reaction following solution to identify sodium- in acid medium, which produces free iodine containing substances: that colors chloroform layer. What reagent is used for such a reaction? A. Potassium pyroantimonate B. Potassium permanganate A. Sodium nitrite C. Sodium citrate B. Silver nitrate D. Potassium carbonate C. Barium chloride E. Barium hydroxide D. Sodium carbonate E. Ammonium oxalate 27. An analytical chemist performs collargol identification by means of ashing. Obtained 33. An analytical chemist determines residue is then dissolved in hydrochloric potassium ions admixture in a medicinal acid. Specify the analytical effect that is substance with sodium tetraphenylborate observed in this case: according to the State Pharmacopoeia of Ukraine. What analytical effect would A. White precipitate confirm the presence of this admixture? B. Black precipitate C. Yellow precipitate A. White opalescence D. Blue precipitate B. Yellow coloring E. Light green precipitate C. Blue coloring D. Pink coloring 28. Calcium gluconate is being tested E. Brown coloring for presence of admixtures of saccharose and reducing sugars with copper-tartrate 34. What corticosteroid medicinal substance Фармацевтична хiмiя 5 has two fluorine atoms in its chemical alcohol medium. This drug is: structure? A. Boric acid A. Fluocinolone acetonide B. Benzoic acid B. Dexamethasone C. Salicylic acid C. Triamcinolone acetonide D. Glutaminic acid D. Prednisolone E. Acetylsalicylic acid E. Hydrocortisone acetate 41. Bromatometry allows quantitative 35. A private pharmacy received a supply analysis of the following drug: of a drug with 2.3-dihydro-2-methyl-1.4- naphthoquinone-2-sulfonate sodium as an A. Sodium salicylate active ingredient. Name this drug: B. Glutamic acid C. β-Alanine A. Vicasol (Menadione) D. Benzoic acid B. Rutin E. Potassium acetate C. Riboflavin D. Ergocalciferol 42. What drug, due to β-lactam ring in E. Cocarboxylase hydrochloride its structure, has positive reaction with hydroxylamine hydrochloride solution in 36. The reaction of glucose identification the presence of sodium hydroxide with produces red precipitate with the following subsequent addition of iron (III) chloride reagent: solution? A. Copper-tartrate A. Amoxicillin trihydrate B. Thiocyanogen bromide B. Metronidazole C. Ammoniacal silver nitrate solution C. Papaverine hydrochloride D. Alkaline potassium tetraiodomercurate D. Phenazone solution E. Dibazol (Bendazol) E. Sodium nitroprusside solution 43. A technological controller uses Marquis 37. During quantitative determination of reagent to identify the substance of Vicasol (Menadione) by means of cerimetry, acetylsalicylic acid after acid hydrolysis. the following indicator is used: Positive effect of the reaction would be indicated by the following coloring: A. Ferroin B. Naphtholbenzein A. Pink C. Crystal violet B. Blue D. Methyl orange C. Yellow E. Methyl red D. Green E. Violet 38. As the result of reduction of alcoholic solutions of 5-nitrofuran derivatives by 44. Nicotinamide is a pyridine derivative, means of their reaction with zinc in the which can be identified by its positive presence of diluted hydrochloric acid, the reaction with: following occurs: A. Cyanogen bromide reagent A. Solution decoloration B. Copper-tartrate solution B. Precipitation C. Grade reagent C. Ammonia production D. Thioacetamide reagent D. Color change from yellow to black E. Thioglycolic acid solution E. Precipitation and gassing 45. According to the State Pharmacopoeia 39. A certain drug explodes when heated of Ukraine, an analytical chemist should to 180oC or upon impact and, therefore, use acidimetry in non-aqueous medium must be handled carefully during receipt and to determine quantitative content of the storage. This drug is: following purine alkaloid: A. Nitroglycerine solution A. Caffeine B. Activated carbon B. Theobromine C. Alcoholic iodine solution C. Caffeine and sodium benzoate D. Barium chloride D. Theophylline ethylenediamine E. Calcium chloride E. Theophylline 40. A certain drug can be quantitatively 46. An analytical chemist performs assessed by means of direct alkalimetry identification of lidocaine hydrochloride. in glycerine, mannitol, or other polyhydric According to the State Pharmacopoeia of Фармацевтична хiмiя 6

Ukraine the presence of chloride ions can be A. Starch confirmed by means of reaction with silver B. Potassium chromate nitrate solution resulting in: C. Eriochrome black D. Methyl orange A. White caseous precipitate E. Bromthymol blue B. Green fluorescence C. Violet coloring 51. To identify pilocarpine hydrochloride D. Yellow precipitate it is necessary to use reaction with sodium E. Blue coloring nitroprusside in an alkaline medium (Legal’s test). Resulting cherry-red coloring 47. According to the State Pharmacopoeia confirms presence of the following in the of Ukraine, an analytical chemist can pilocarpine structure: determine sulfate admixtures in sodium tetraborate by the effect of white A. Lactonic ring opalescence that results from its reaction B. Imidazole ring with the following solution: C. Methylene group D. Chloride ions A. Barium chloride E. Methyl group B. Ammonium oxalate C. Magnesium sulfate 52. According to the State Pharmacopoeia D. Sodium sulfide of Ukraine, phthalylsulfathiazole is E. Silver nitrate quantitatively determined by means of alkalimetry in non-aqueous medium. The 48. According to the State Pharmacopoeia following substance is used as a solvent in of Ukraine quantitative content of salicylic this case: acid is to be determined by means of: A. Dimethyl formamide A. Alkalimetry B. Anhydrous acetic acid B. Nitritometric titration C. Ethyl alcohol C. Complexometric titration D. Benzene D. Acidimetry E. Chloroform E. Argentometry 53. A control laboratory needs to analyze 49. An analytical chemist conducts streptomycin powder for injections. quantitative determination of ibuprofen According to the State Pharmacopoeia of (substance) by means of direct alkalimetry. Ukraine, to identify it sodium hydroxide The following solution will be an indicator is added into the dissolved powder, the in this case: resulting substance is heated, and then iron (III) chloride solution is added, which A. Phenolphthalein results in violet coloring of the substance. B. Tropeolin 00 This test is known as: C. Mordant black D. Potassium chromate A. Maltol test E. Ammonium iron (III) sulfate B. Ninhydrin test C. Vitali-Morin reaction 50. What indicator is used in iodometry for D. Biuret test quantitative determination of caffeine in E. Thiochrome test caffeine and sodium benzoate? Фармакогнозiя 7

1. Vitali-Morin’s reaction is used to 7. During microscopy of althaea root it identify tropane alkaloids in herbal raw is necessary to determine the presence of material. Name the alkaloid that can be starch granules within the plant cells. What detected by means of this specific reaction: reagent enables such analysis? A. Scopolamine A. Lugol’s solution B. Codeine B. Ammonium hydroxide C. Morphine C. Concentrated sulfuric acid D. Platyphyllin D. Alcohol solution of α-naphthol E. Papaverine E. Thymol solution 2. What herbal bioactive substances yield 8. Preparations of sorrel roots can have both a positive reaction with ferric ammonium a laxative and astringent effect. This is due alum solution? to the presence of the following biologically active substances: A. Tannins B. Saponins A. Anthracene derivatives and tannins C. Polysaccharides B. Flavonoids and essential oils D. Bitters C. Essential and fatty oils E. Fatty oils D. Coumarins and phenol glycosides E. Iridoids and vitamins 3. Standard herbal material of lily-of- the-valley is obtained by drying it at a 9. Motherwort grass is a component of temperature of 50-60oC to prevent the hypotensive and sedative drugs. This herbal following possible biochemical process: raw material should be harvested taking into account its renewal rate. Therefore it can be A. Enzymatic hydrolysis of cardiac glycosides harvested: B. Oxidation of phenolic compounds C. Volatilization of essential oils A. Once every 5 years D. Oxidation of resins B. Once every 2 years E. Oxidation of terpenoids C. Once every 3 years D. Once every 10 years 4. Proper harvesting of Frangula alnus E. Every year herbal raw material greatly influences the quality and quantity of its active substances. 10. A certain type of herbal raw material is Therefore the optimal time for buckthorn being harvested in spring during sap flow. bark harvesting is the period of: Specify this material: A. Sap flow A. Bark B. Fruiting B. Flowers C. Flowering C. Buds D. Defoliation D. Roots E. Dormancy E. Infructescences 5. Drugs derived from Rauvolfia serpentina 11. To determine the quantity of wild- roots are used in hypertension treatment. growing medicinal plants, it is necessary to Authenticity of Rauvolfia serpentina herbal know their area of vegetation and yield per raw material can be confirmed by its content unit area. Yield of Thymus serpyllum grass of: can be determined by the following method: A. Reserpine A. Projective cover method B. Atropine B. Permanent quadrate method C. Hyoscyamine C. Visually D. Vinblastine D. Model sample method E. Adonitoxin E. Geodesically 6. Medications Passit and Novopassit are 12. Codeine is used as a cough-depressant. used as tranquilizing, sedative and mild What herbal raw material contains this hypnotic agents. These medications are alkaloid? produced from the following grass: A. Pods of opium poppy A. Purple passionflower B. Grass of plume poppy B. Three-lobe beggarticks C. Celandine grass C. Garden sage D. Grass of common periwinkle D. Elecampane E. Tea leaves E. Lesser periwinkle 13. What herbal drug produced form Фармакогнозiя 8 alkaloid-containing raw materials can be A. Iridoids recommended for neurasthenia, insomnia, B. Essential oils menopausal disorders? C. Alkaloids D. Polysaccharides A. Novopassit E. Saponins B. Ergotamine C. Glaucine hydrochloride 19. Specialists of a pharmaceutical D. Securinine nitrate enterprice confirm the identity of Cassia E. Vinblastine acutifolia herbal raw material. During reaction with alkali it developed cherry-red 14. A teenager with hyporexia has been coloring. What substances were identified? recommended to drink medicinal herbal tea of the following composition: Herba A. Anthraquinones Absinthii, Herba Millefolii. Specify the B. Tannins characteristic microscopic features of C. Alkaloids Artemisia absinthium, which indicate its D. Glycosides presence in the herb mixture: E. Iridoids A. T-shaped hairs along the leaf edge 20. Menthol has anesthetic and antiseptic B. Simple and capitate hairs effect. What plant is the source of menthol? C. Branched, simple and ciliated hairs D. Retor-shaped hairs A. Folia Menthae piperitae E. Branched and capitate hairs B. Folia Uvae ursi C. Folia Eucalypti 15. Representatives of the family Solanaceae D. Folia Salviae are widely used in medical practice E. Folia Absinthii as alkaloid-containing plants. Which representative is the source for production 21. The thyme grass is used for the of semi-synthetic steroid hormones? production of herbal medical products for the treatment of respiratory tract infections. A. Solanum laciniatum Under the State Pharmacopoeia of Ukraine B. Atropa belladonna the herbal raw material is subject to C. Datura Stramonium chromatographic identification by means of D. Hyoscyamus niger thin layer chromatography.What substances E. Solanum tuberosum are detected on the chromatographic plate after its treatment with due reagent? 16. Birch buds are used as a diuretic. Quality of the herbal raw material is determined by A. Thymol and carvacrol its content of: B. Atropine and hyoscyamine C. Quercetin and rutin A. Essential oil D. Apigenin and luteolin B. Vitamins E. Arbutin and methyl arbutin C. Lipids D. Iridoids 22. Yarrow grass is a component of herbal E. Saponins gastrointestinal remedies and is used to make herbal drugs. According to the State 17. Standardization of a certain herbal raw Pharmacopoeia of Ukraine the quality of material is done by calculating its alkaloid this herbal raw material is assessed by its content in terms of hyoscyamine. Name this content of: herbal raw material: A. Essential oils and proazulenes A. Folia Belladonnae B. Alkaloids B. Radices Berberidis C. Polysaccharides C. Herba Chelidonii D. Cardiac glycosides D. Herba Thermopsidis lanceolatae E. Vitamines E. Fructus Capsici 23. Snake venom-based drugs are widely 18. Valerian roots and rhizomes are applied in treatment of locomotor apparatus processed in the phytochemistry workshop diseases. Main components of these venoms to produce tinctures and thick extracts that are: are the components of combined sedatives. Name the group of bioactive compounds A. To x i c p r o t e i n s that includes valerian valepotriates, - B. Alkaloids valtrate, acevaltrate, and dihydrovaltrate: C. Cardiac glycosides D. Glucosinolates E. Phenol-alcohols Фармакогнозiя 9

24. The cholagogue derived from Rosa 30. Essential oil of a certain plant contains canina fruit is used in treatment of liver and up to 80% of cineole. Specify the herbal raw gallbladder diseases. Name this drug: material that is collected from this plant: A. Cholosas A. Folia Eucalypti B. Chophytol B. Folia Betulae C. Phytolyt C. Folia Menthae piperitae D. Allochol D. Folia Мelissae E. Altan E. Folia Absinthii 25. A medicinal plant contains hydroxycoumarins 31. To identify cardiac glycosides there are and is used in production of venotonic usually three groups of color reactions being agents. Name the herbal raw material performed: for steroid nucleus, for lactonic harvested from this plant: ring, and for carbohydrate component. Specify the reaction for identification of A. Semina Hippocastani butenolide ring: B. Herba Meliloti C. Fructus Ammi majoris A. Legal’s test D. Fructus Pastinacae sativae B. Stahl’s reaction E. Fructus Dauci carotae C. Mayer’s test D. Reaction of sublimation 26. Senna (cassia) foliage contains E. Dragendorff’s test anthracene derivatives. Their presence can be confirmed by qualitative reaction with: 32. What fatty oil is nondrying due to its oleic acid glyceride content? A. Alkali B. Molisch’s reagent A. Ricini oleum C. Iron ammonium alum B. Helianthi oleum D. Iron (II) sulfate C. Maydis oleum E. Fehling’s reagent D. Cucurbitae oleum E. Lini oleum 27. Digoxin is given to the patients with chronic heart failure. What medicinal plant 33. Several species of Polygonum genus are that contains cardiac glycoside is a source of used in medicine. One of these species has this medicinal substance? rootstocks rich in tanning agents, which are used to treat diarrrhea. Name this species: A. Digitalis lanata B. Erysimum canescens A. Polygonum bistorta C. Strophanthus kombe B. Polygonum hydropiper D. Adonis vernalis C. Polygonum persicaria E. Convallaria majalis D. Polygonum aviculare E. Polygonum alpinum 28. Vinblastine and Vincristine demonstrate antitumor activity. Name the herbal raw 34. Hyoscyamine and scopolamine are material used in production of these typically contained in the plants of the medicines: following family: A. Folia Catharanthi rosei A. Solanaceae B. Herba Vincae minoris B. Asteraceae C. Rhizomata Nupharis lutei C. Papaveraceae D. Folia Berberidis D. Apocynaceae E. Herba Selaginis E. Fabaceae 29. A pharmaceutical warehouse received a 35. Spectrophotometric analysis of herbal raw material that consists of ”cones” anthracene derivatives contained in with loose scales that are attached to a firm buckthorn bark is based on the following twig with or without fruits. Its collective reaction: fruits are pale green, fragrant, and bitter. Name the plant from which this herbal raw A. Production of phenolates with alkali- material was harvested: ammonia solution B. Oxidation of anthracene derivatives A. Humulus lupulus C. Anthraquinone reduction B. Alnus incana D. Salt precipitation C. Juniperus communis E. Sublimation D. Rubus idaeus E. Olea europeaea 36. A certain herbal raw material is used to make Flamin cholagogue. Name this Фармакогнозiя 10 material: are used as laxatives in medicine. According to the State Pharmacopoeia of Ukraine, A. Helichrysi arenarii flores during chromatographic identification of B. Meliloti herba buckthorn bark it is necessary to detect: C. Violae herba D. Tanaceti flores A. Glucofrangulins E. Cratаegi flores B. Panaxosides C. Lanatosides 37. In the process of phytochemical D. Ginkgosides examination of buckthorn bark, the reaction E. Purpurea glycosides with alkaline solution resulted in red coloring, which indicates the presence of the 41. Helichrysum arenarium herbal raw following: material has anti-inflammatory and choleretic effect. What parts of this plant A. Anthracene derivatives are harvested? B. Saponins C. Alkaloids A. Flowers D. Flavonoids B. Grass E. Slime C. Rhizomes D. Fruits 38. Atropa belladonna grass extract is a E. Roots component of compound antispasmodic drugs. Select such drug from the list: 42. A substance was received for analysis. The substance is a round seed 1-1,8 mm A. Bellasthesin in diameter, yellow with bluish tint. When B. Olimetinum mashed with water, emits characteristic C. Solutan irritant odor; is sharp and acrid to taste. The D. Urolesan raw material can be identified as: E. Herbogastrine A. Mustard seeds 39. A pharmaceutical warehouse has B. Flax seeds received a batch of herbal raw material C. Plantago psyllium seeds - hawthorn flowers. Merchandise analysis D. Fenugreek seeds revealed in one of the sacks significant E. Nigella seeds amount of bird-cherry flowers besides the hawthorn. What quality assessment of the 43. What effect will anthracene derivatives herbal raw material should be performed? have, if -OH- groups are located in both benzene rings of anthraquinone? A. Acceptable admixtures B. Mineral admixtures A. Laxative C. Moisture content B. Diuretic D. Ash values (Total ash) C. Litholytic E. Extractive values D. Sedative E. Choleretic 40. Buckthorn bark and its derivative drugs Аптечна технологiя лiкiв 11

1. To improve iodine solubility in the optimal isotonic agent in this case: purified water, iodine must be: A. Sodium chloride A. Dissolved in the saturated solution of B. Sodium sulfate potassium iodide C. Glucose B. Dissolved in the boiling water D. Boric acid C. Reduced to fine powder E. Sodium nitrite D. Dispersed with glycerine E. Comminuted with alcohol 8. A pharmacist has made a drug by the prescription: 2. A pharmacist prepares fat-based Rp.: Sol. Protargoli 0,31,0 suppositories by pouring. Specify the type D.S. For irrigation. of fatty vehicle in this case: Specify the optimal technology of preparation: A. Butyrol B. Vaseline (petroleum jelly) A. Grind protargol in the mortar with C. Cocoa butter glycerine, add water D. Wax B. Dissolve glycerine in the water, add E. Spermaceti protargol C. Dissolve protargol in the water, add 3. To prepare a suspension a medicinal glycerine substance should be triturated with a small D. Measure out protargol into the vial, amount of liquid. Specify the optimal dissolve it in the water, add glycerine amount of liquid for trituration of 10 g of E. Measure out subsequently glycerine, zinc oxide according to the Deriagin’s rule: water, and protargol into the vial A. 5ml 9. The doctor prescribed a patient 100 ml of B. 10 ml thermopsis grass infusion. How much of the C. 2ml dry concentrate of thermopsis grass (1:1) D. 1ml should the pharmacist measure out for this E. 0,5 ml patient? 4. A doctor has prescribed pessaries of A. 0.25 g unspecified mass. What mass should be B. 0.5 g chosen when pessaries are being prepared C. 0.3 g in a pharmacy? D. 0.2 g 0.1 g A. 4,0 E. B. 3,0 10. A patient needs the pharmacy to C. 1,5 prepare him a camphor ointment. What D. 0,5 concentration of camphor should be in E. 6,0 the ointment according to the regulatory documents? 5. A pharmacist has made an injection solution that contains a salt produced by A. 10% reaction of a strong base with a weak acid. B. 20% Specify the necessary stabilizer: C. 15% Sodium hydrochloride D. 5% A. 1% B. Sodium sulfate E. C. Hydrochloric acid 11. Urethral suppositories are being made D. Ascorbic acid for a patient. What parameters should be E. Cysteine specified by the doctor in the formulation for the pharmacist to be able to calculate the 6. A pharmacist prepares an injection solution that must be stabilized with 0,1M necessary amount of the vehicle correctly? of hydrochloric acid solution. What solution A. Diameter, length, and quantity of the is to be prepared? supositories B. Diameter and quantity of the supositories A. Novocaine Length and quantity of the supositories B. Calcium chloride C. Potassium chloride D. Diameter and vehicle of the supositories C. E. Quantity and vehicle of the supositories D. Hexamethylenetetramine E. Sodium benzoate 12. A pharmacy prepares 10% sodium chloride injection solution. What 7. A pharmacist needs to prepare eyedrops with pilocarpine hydrochloride. Specify the sterilization would be optimal in this case? Аптечна технологiя лiкiв 12

A. Suspension ointment A. Autoclave chamber with high-pressure B. Solution ointment saturated steam C. Hydrophilic ointment B. Sterile filtration through membrane D. Combined ointment C. Gas sterilization E. Extraction ointment D. Dry-heat sterilization E. Irradiation sterilization 18. To stabilize the suspension a pharmacist has used potassium soap. What substance 13. Prior to making a sodium chloride does this suspension contain? isotonic solution a pharmacist baked the powder in a dry heat box. What substances A. Sulfur are removed by this operation? B. Phenyl salicylate C. Menthol A. Pyrogenic substances D. Basic bismuth nitrate B. Redox substances E. Camphor C. Sulfates D. Chlorides 19. A pharmacist has prepared a compound E. Moisture ointment. What is the correct sequence of its preparation? 14. A pharmacy received an infusion formulation. What herbal raw material can A. Suspension - solution - emulsion be used to make this dosage form? B. Solution - emulsion - suspension C. Emulsion - suspension - solution A. Valerian roots with rhizomes D. Solution - suspension - emulsion B. Rhubarb roots E. Emulsion - solution - suspension C. Oak bark D. Arrow-wood bark 20. To prepare decoctions with the volume E. Buckthorn bark of 1000-3000 ml, they should be infused in a boiling water bath for: 15. A pharmacist has prepared an eyedrops vehicle. What method of sterilization should A. 40 minutes be chosen in this case? B. 25 minutes C. 30 minutes A. Dry heat D. 45 minutes B. Flowing steam E. 15 minutes C. Pasteurization D. Ultraviolet irradiation 21. What medicinal agents must be E. Membrane filtration manufactured in aseptic conditions followed by thermal sterilization with high-pressure 16. A pharmacist has prepared a drug by the saturated steam? prescription: Rp.: Olei Helianthi 7,4 A. Injection solutions with thermostable Solutionis Ammonii caustici 2,5 ml substances Асidi oleinici 0,1 B. Injection solutions with thermolabile M. D. S:. Ammoniac liniment. For infriction. substances Specify the type of disperse system: C. Concentrated solutions for burette systems A. Liniment-emulsion D. Liquid ingestible antibiotics B. Combined liniment E. 2% collargol solution for infants C. Liniment-solution D. Liniment-suspension 22. When preparing dermatological E. Extractive liniment ointments the following substance should be introduced by suspending: 17. A pharmacist has prepared a drug by the prescription: A. Xeroform Rp.: Streptocidi B. Camphor Dermatoli ana 1,0 C. Menthol Lanolini D. Protargol (silver proteinate) Vaselini ana 5,0 E. Ephedrine hydrochloride M.D.S.: Apply to the affected skin. 23. What is the function of anhydrous Specify the type of the disperse system: lanolin in the suppository mass used for suppositories prepared via hand rolling? Аптечна технологiя лiкiв 13

A. Plasticizer A. Vaseline (petroleum jelly) B. Solvent B. Glycerine C. Preservative C. Purified water D. Solubilizer D. Glycerine-water solution E. Emollient E. Dimethylsulfoxide 24. A paharmacist makes powders by 30. Standard stactometer divides 1 ml of grinding one of the formulation components water into: with ethyl alcohol. This technology is typically applied when working with the A. 20 drops following substance: B. 15 drops C. 25 drops A. Streptocid D. 30 drops B. Starch E. 10 drops C. Ta l c u m D. Zinc oxide 31. To prepare eyedrops with antibiotic a E. Bolus alba dispensing chemist has been using flowing steam sterilization under 100oC for 30 25. A pharmacist prepares suppositories minutes. What antibiotic allows for such by pouring. Name the coefficient sterilization? for substitution of fatty vehicle with glycerinated gelatin vehicle: A. Levomycetin (Chloramphenicol) B. Sodium benzylpenicillin A. 1.21 C. Streptomycin sulfate B. 1.20 D. Biomycin C. 1.31 E. Erythromycin D. 1.11 E. 1.25 32. A pharmacist prepares 180 ml of adonis grass infusion. How much herbal raw 26. What technology should be chosen by a material should be taken to prepare this pharmacist to make a liquid dosage form, if infusion? it contains calcium gluconate? A. 6.0 A. Dissolve it in hot solvent or heat it up to B. 10.0 full dissolution C. 2.0 B. First grind it into powder when it is dry or D. 15.0 with small amount of solvent added E. 18.0 C. Dissolve in the water free of redox subsatances 33. A pharmacy prepares a drug that D. Add equal amount of sodium chloride contains a high-molecular compound with E. Dissolve in alkaline medium unlimited swelling ability. Name this material: 27. A pharmacy received a prescription for compound powders containing a coloring A. Pepsin agent. Which of the powder components B. Methylcellulose given below is a colouring agent? C. Gelatine D. Starch A. Ethacridine lactate (Rivanol) E. Protargol B. Camphor C. Sulfanilamide 34. A pharmacy has received a prescription D. Bismuth nitrate for colloid solution. Name this solution: E. Silver proteinate (Protargol) A. Collargol solution 28. Infuser apparatus is used by a pharmacy B. Sodium chloride solution to prepare: C. Nonaqueous solution D. 5% glucose solution A. Infusions and decoctions E. Burow’s solution B. Infusion solutions C. Suspensions 35. A pharmacy has received a formulation D. Emulsions for the solution with a substance that E. Ointments moderately expands in the cold water. Name this substance: 29. Specify the fluid used to coat the forms for pouring of the suppositories with hydrophilic vehicles: Аптечна технологiя лiкiв 14

A. Gelatin to make an eye ointment. Specify this B. Glucose medicinal substance: C. Calcium chloride D. Sodium chloride A. Pilocarpine hydrochloride E. Protargol (Silver proteinate) B. Xeroform C. Menthol 36. A pharmacist prepares an infusion in D. Basic bismuth nitrate proportion 1:400. Specify the herbal raw E. Purified sulfur material used in this infusion: 41. A powder containing a substance with A. Thermopsis grass specific weight has been prepared in a B. Motherwort grass pharmacy. Name this substance: C. Oak bark D. Althaea roots A. Basic bismuth nitrate E. Camomile grass B. Sugar C. Bolus alba 37. A pharmacist prepares a chamomile D. Ta l c u m flowers infusion. Specify the proportion of E. Sodium bicarbonate raw material to infusion: 42. Weibel’s liquid is necessary to stabilize A. 1:10 the solution of a certain substance. Name B. 1:30 this substance: C. 1:50 D. 1:400 A. Glucose E. 1:20 B. Novocaine C. Potassium chloride 38. 50 ml of injection solution has been D. Sodium chloride made in a pharmacy. Specify the process of E. Magnesium sulfate solution sterilization: 43. A powder with a hard to disintegrate A. 120oC - 8 minutes substance has been made in a pharmacy. B. 180oC - 30 minutes Specify this substance: C. 160oC - 15 minutes D. 140oC - 12 minutes A. Camphor E. 110oC - 15 minutes B. Sodium chlorides C. Osarsolum (Acetarsol) 39. A pharmacist prepares 100 ml of glucose D. Ta l c u m solution. Specify the amount of Weibel’s E. Sugar stabilizer necessary in this case: 44. Choose the solvent necessary to A. 5ml prepare a concentrated solution of sodium B. 10 ml bicarbonate in the pharmacy: C. 15 ml D. 20 ml A. Purified water E. 2ml B. Peach-kernel oil C. Chloroform 40. A pharmacist has dissolved a medicinal D. Vaseline (petroleum jelly) substance in the sterile purified water E. Ethanol Заводська технологiя лiкiв 15

1. A pharmaceutical company produces A. Syringe a medicine under the brand name B. Vacuum ”Corglyconum”. What herbal raw material C. Devaporation is used in preparation of this drug? D. Syringe and vacuum E. Syringe and devaporation A. Lily-of-the-valley grass B. Wormwood grass 7. Production of tablets requires stage-to- C. Dandelion roots stage quality control. What devices are used D. Plantain foliage to determine the particle size distribution E. Buckthorn bark (fraction) of granules? 2. A factrory workshop producing A. Standard set of sieves suspensions and emulsions is going to B. Various vibrosieves develop the manufacture of new drugs. What C. Friabilators mechanisms can be used for the ultrasound D. Laboratory identifiers processing of drugs? E. Microscope A. Liquid whistle, magnetostrictive source 8. Among various types of tablet external B. Dismembrator, electrical impulse layers there are enterosoluble coatings. plasmolyzer Where in the body are they dissolved? C. Disintegrator, liquid whistle D. Rotor-pulsation apparatus, dismembrator A. Intestine E. Centrifugal mixer with rotating housing B. Stomach C. Oral cavity 3. A pharmaceutical factory produces tablets D. Rectum of sodium chloride. What is the method of E. Esophagus their poduction? 9. Specify the control methods aimed at A. Direct compression without additional detecting mechanical impurities in parenteral substances solutions: B. Moulding C. Direct compression with the addition of A. Visual optical excipients B. Limulus test D. Wet granulation prior to compression C. Amperometric E. Dry granulation prior to compression D. Gravitational E. NMR and UV-visible spectroscopy 4. There are various groups of adjuvants used in tablet production. What is the function of 10. What stage is the last in making injection excipients? solutions? A. To make pills of a certain weight A. Labeling B. To create necessary adhesive force between B. Sterilization particles C. Filtering C. To improve disintegration D. Qualitative control D. To improve the flowability of granular E. Quantitative control material E. To improve the taste 11. Specify the indicator that measures the total contribution of various solutes to the 5. Various types of dryers can be used for osmotic pressure of the solution: granule dehumidification. Specify the type of ”СП-30” dryer: A. Osmolality B. Isohydricity A. Fluidized bed dryer C. Isotonicity B. Freeze dryer D. Isoviscosity C. Infrared dryer E. Apyrogenicity D. Silica gel dryer E. Forced air dryer 12. Dosage precision during tablet making mainly depends on the following 6. Ampoule workshop of a factory produces technological property of tablet mass: 5% oil solution of tocopherol acetate for injections. What method of filling the A. Flowability ampoules is optimal in this case? B. Relative density C. Compression ratio D. Compressibility E. Lyophilic property 13. Quality of dried extracts is assessed according to several criteria. Specify the Заводська технологiя лiкiв 16 highest acceptable amount of moisture A. Amount and nature of disintegrating in dried extracts according to the State agents Pharmacopoeia of Ukraine: B. Poor flowability C. High specific gravity of powders A. 5% D. Tablet powder contains lamellar crystals B. 25% E. Heterogeneity of granulated material C. 20% D. 75% 20. A pharmaceutical company produces E. 95% essential oils via a method that consists of essential oil transfer into gas phase followed 14. Tyndallization is used at a pharmaceutical by its absorption with fats and then its factory as a sterilization method for extraction with alcohol. Name this method: thermolabile substances. Essentially this method consists of: A. Enfleurage B. Compression A. Triple heating of solution to 40-60oC C. Extraction with 24-hour-long intervals in between for D. Hydrodistillation thermostating E. Dynamic sorption B. Autoclaving at 119-121oC with pressure at 1.0-1.1 atm 21. A pharmaceutical company produces C. Sterilization with flowing steam at 100oC belladonna tincture. In the process of D. Sterilization with dry heat at 180-200oC for standardization, excessive content of active a lengthy period of time substances was detected. How can this E. Sterilization with high-frequency and situation be remedied? microwave frequency current A. Dilute the tincture with extractant to 15. When an extractant is filtered through a normal concentration herbal raw material to obtain an extract of B. Precipitate excessive active substances the substances soluble in this extractant, this C. Filter the tincture through adsorbent process is called: D. The tincture is a non-recoverable reject material A. Percolation E. This kind of deviation is not important B. Maceration C. Remaceration 22. The phytochemical workshop of a factory D. Turbo extraction produces liquid extracts. What extractants E. Steeping are used in this manufacturing process? 16. Phytochemical workshop of a factory A. Aqueous-alcoholic solutions manufactures pancreatin. What is the source B. Chloroform material for obtaining pancreatin? C. Ammonia solution D. Dichloroethane A. Pancreas of pigs or cattle E. Water B. Gastric mucosa of pigs C. Lungs of cattle 23. A pharmaceutical company produces D. Heart of cattle tablets. Tabletting by means of direct E. Egg white compression requires: 17. The following substance is used as an A. No prior granulation extractant in production of liquid extracts: B. Prior granulation C. Formation of masses A. Ethanol D. Prior homogenization B. Acetone E. Application of hydraulic press C. Dichloroethane D. Chloroform 24. A pharmaceutical company produces E. Glycerine suppositories made from thermolabile medicinal substances. What method is used 18. Propellants are used in aerosols in their production? production. Specify the function of propellants: A. Pressing B. Steeping A. Create pressure in the package C. Pouring B. Action prolongation D. Rolling C. Stabilization E. Dispersion D. Emulsification E. Dispersion 25. A pharmaceutical company produces liquid dosage forms. What principle is used 19. What factors affect tablet disintegration? in rotary pulsation apparatus to obtain an emulsion? Заводська технологiя лiкiв 17

31. Name the optimal vehicle for soluble A. Mechanical dispersion vaginal suppositories: B. Ultrasonic dispersion C. Solubilization A. Polyethylene oxide D. Coacervation B. Cocoa butter E. Maceration C. Glycerine D. Fat 26. A pharmaceutical company produces E. Hard fat aromatic waters. Peppermint water should be prepared in the following proportion: 32. What tablet coating protects stomach from harmful influence of active ingredients? A. 1:1000 B. 1:2000 A. Intestinally absorbed C. 1:4000 B. Water-soluble D. 1:10 C. Gastrically absorbed E. 1:1 D. Fat-soluble E. - 27. A pharmaceutical company produces soft dosage forms. What indicator should be 33. In the process of industrial production measured additionally for the soft dosage of rectal suppositories, certain substances forms that are intended for application on insoluble both in water and suppository heavily damaged skin? vehicle are introduced into this dosage form. Specify the optimal way to introduce these A. Sterility substances: B. pH C. Identification A. Introduce the substances as a suspension D. Microbiological purity B. Introduce the substances as an emulsion E. Quantitative determination C. Dissolve the substances in the water heated to 45oC 28. A pharmaceutical company produces D. Melt a part of fatty vehicle and dissolve the warious medicines. Name the dosage form substances there consisting of separate hard dry particles E. Melt all of fatty vehicle and dissolve the disintegrated to varying degree: substances there A. Powders 34. In the process of industrial production, B. Ta b l e t s certain adjuvants are included in the soft C. Suspensions dosage forms as pH regulators. Name these D. Emulsions adjuvants: E. Dried extract A. Citric acid, sodium phosphate salts 29. Core tablets that are to be made into B. Paraffin, spermaceti dragees must not have a flat shape. Why such C. Glycerine, dimethyl sulfoxide requirement is necessary? D. Sodium lauryl sulfate, tween emulsifiers E. Benzalkonium chloride, benzyl alcohol A. To prevent them from adhesion to each other 35. Polyethylene oxide base belongs to the B. They are not durable enough following group: C. To avoid prolonged contact with overlaying suspension A. Hydrophilic D. To improve their appearance B. Hydrophobic E. To speed up the process of applying the C. Amphiphilic coating D. Emulsion E. Fat 30. Specify the formula of extractant calculation in the process of creating a 36. During storage, suspension instability tincture: manifests itself as:

A. V = Vtincture + mrawmaterial ·Kalcoholabsorption A. Sedimentation of particles B. mrawmaterial = mendproduct + mlosses B. Flocculation of particles C. E = mlosses · 100% C. Dissolution of particles mrawmaterial mendproduct D. Caking of particles D. µ = · 100% mrawmaterial E. Change of particles shape E. V = Vtincture · n + mrawmaterial · Kalcoholabsorption Органiзацiя та економiка фармацiї 18

1. A pharmacy prepares drugs by of a medicine allows its classification as over- individual prescriptions. How often should the-counter drug? the floors be mopped down in the prescription department? A. Medicine can cause no direct or indirect harm to the patient’s health A. Once in a shift B. Medicine is available only for in-patient B. Once in a week treatment C. Once every 10 days C. Medicine contains substances that require D. Once every 5 days additional research into their activity and E. Once every 3 days side-effects D. Medicine is available only by prescription 2. Schedule of sanitation actions in E. Medicine has entered the pharmaceutical pharmacies is regulated by the relevant market only resently and actual experience regulatory acts. Cleaning day at a pharmacy with its practical application is limited must be scheduled at least once: 8. Who is responsible for the acceptance A. In a month of goods and medical products with B. In a week accompanying incoming quality control? C. In 3 days D. In 10 days A. Authorized representative E. In 5 days B. Supplier pharmacist C. Dispensing chemist 3. Which of the pharmacy departments is D. Pharmacy head manager responsible for checking the quantity and E. Analyst quality of received goods, their storage and dispensing to other departments? 9. A pharmacy receives centralized deliveries of goods from the warehouse. Specify the A. Inventory department document that is NOT NECESSARY for B. Compounding and production department accounting of goods receipt by the pharmacy: C. Department of finished dosage forms D. Department of over-the-counter drugs A. Cash receipt order E. Department of curative cosmetics B. Goods report (Inventory change report) C. Goods received record book by groups of 4. A pharmacy opens a bank account to goods store funds and conduct ongoing business D. Goods received record book by item and transactions. What kind of account should be supplier opened? E. Financial operating report of the pharmacy A. Current 10. An accountant conducts necessary B. Provisional calculations for remuneration of labor. Name C. Deposit the type of remuneration that is due for labor D. Letter of credit carried out according to the work standards E. Investment and is paid within the amount determined by basic or piece wages for factory workers and 5. Natural persons registered as small salaries for office workers: business entities with simplified taxation scheme are subject to limitation of the A. Basic pay annual amount of sales proceeds. Specify the B. Bonus proceeds limit: C. Increment One-off payment 500 000 UAH D. A. E. Financial aid B. 750 000 UAH C. 100 000 UAH 11. A dispensing chemist with calculated D. 3 000 000 UAH length of service of 7 years has fallen ill. E. 5 000 000 UAH What percent of the sum stated in her sick list would she receive? 6. What final document is used for the preparation of the report on the A. 80% discrepancies revealed in the course of B. 100% inventory at the pharmacy? C. 70% 60% Act on the inventory results D. A. E. 50% B. Inventory item description C. Checklist 12. Commercial and financial activity of a D. Commercial report pharmacy involves using returnable tare. E. Invoice Which of the following containers are returned to the supplier? 7. What pharmacotherapeutic characteristic Органiзацiя та економiка фармацiї 19

A. Metal cylinders A. Monetary funds B. Packaging materials B. Equity capital C. Paper boxes C. Bank loans D. Glass-stoppered bottles D. Debt settlement with the creditors E. Glassware E. Salaries payment 13. How often should a pharmacy make an 19. According to the rules in force, inventory of its fixed assets? workrooms should regularly undergo humid disinfection. How often should the floors be A. Once a year washed? B. At least thrice a year C. At least once in a quarter A. No less than once in a shift D. Once every three years B. No less than twice in a week E. At least twice a year C. No less than once in a week D. No less than thrice in a week 14. Limit cash balance is the maximum E. No less than twice in a month amount of monetary funds that can remain in the cash desk of an organization at the end 20. When servicing customers it is necessary of a workday. This limit is established by the to maintain cash desk discipline. A cashier following authorities: should make records in the cash book: A. Pharmacy management A. Immediately after the cash transaction B. Chief physician occurred C. Local authorities B. Monthly D. Tax Inspectorate C. Quarterly E. - D. Weekly E. At the end of a workday 15. Inspection of received medicines should be performed by an authorized employee. 21. What department of a wholesale firm What is NOT a part of the responsibilities of is tasked with search for and analysis of this person? potential suppliers’ commercial offers, as well as concluding supply contracts and A. To draw up orders for medicines and supervision of contract fulfillment? medical products, to conclude sales contracts B. To draw up conclusions regarding A. Supply department inspection of received medicines B. Marketing department C. To keep a record book of received C. Shipping department medicines D. Stores development D. To check the pharmacy stock for low- E. Finance department quality or fake medicines E. - 22. The Income Statement of a pharmacy for the first quarter of 20XX contains the 16. Doctor’s prescription fulfills several following entries: goods turnover - 45 000 functions. What function indicates that UAH, production cost of products sold - 30 the doctor bears responsibility for correct 000 UAH, turnover costs - 10 000 UAH. prescription of medicines to the patient? Determine the income: A. Legal A. 5 000 UAH B. Social B. 30 000 UAH C. Informational C. 40 000 UAH D. Technological D. 15 000 UAH E. Economic E. 35 000 UAH 17. Pharmacy premises can be divided into 23. Under the current legislation, full or service rooms and workrooms. Name the partial exemption of persons and legal workroom for storage of medical products: entities from tax payment is called: A. Material storage room A. Tax concession B. Shop floor B. Ta x r a t e C. Washing room C. Ta x D. Aseptic block D. Ta x s y s t e m E. Distillation room E. Subject to taxation 18. Accounting records are classified by the 24. Name the official document on audit type of asset accounting or by their sources. results, which is drawn under the standard Active accounts keep record of the following: procedure and contains conclusions about reporting credibillity and integrity of financial statements of an organization: Органiзацiя та економiка фармацiї 20

certificates issued by drug manufacturers? A. Auditor’s conclusion B. Income statement A. 3 years C. Balance sheet B. 1 year D. Cash flow statement C. 2 years E. Statement of changes in equity D. 6 months E. 5 years 25. In Ukraine the auditor position eligibility requires the candidate to be a Ukrainian 31. Pharmacy employees receive their salary citizen and have the qualification certificate payments twice a month. What should the for work as an auditor within the Ukraine’s cashier do, if a pay day coincides with a territory. The certificate is effective for: holiday? A. 5 years A. To pay the salaries one day earlier B. 3 years B. To pay the salaries after the holiday C. 2 years C. To pay the salaries on the holiday D. 1 years D. To pay the salaries 10 days earlier E. Indefinitely E. There are no regulations regarding payment of salaries in this case 26. The Dobropharma pharmacy manager makes plans for standard stock of various 32. An important indicator of business groups of goods, based on their purpose. activity is profitability of a business. Specify Convenience goods belong to the following the indices that can be used to measure the group: profitability: A. Current demand A. Profit/turnover B. Specific demand B. Turnover/cost price C. Prior delivery C. Turnover/income D. Seasonal accumulation D. Income/turnover E. Single delivery E. Liquidity/solvency 27. Accounts receivable develop in the 33. Difference between the retail price of process of pharmaceutical company work. products sold and the margin determines: Specify where in the balance book they are recorded: A. Production cost B. Markup A. Assets C. Margin B. Liabilities D. Income C. Debit E. Breakeven D. Credit E. Account 34. An accountable person has received a sum of money from the pharmacy cash desk 28. Doctor’s prescription has several to buy a calculator. What document records functions. What function of the prescription the cash flow in such a transaction? allows its participation in the process of payment in cases when medicines should be A. Cash expense order issued free of charge or at a reduced price? B. Cash income order C. Invoice A. Economic D. Receipt B. Social E. Remains unregistered documentarily C. Legal D. Medical 35. Where on the shop floor of a pharmacy E. Technological should various nutritional supplements and health food be placed? 29. To ensure the quality of medicines the pharmacy devotes much attention to quality A. On separate shelves and in separate control. The following document is the shopwindows quality assurance of a drug: B. By their pharmacotherapy group C. By their application A. Quality certificate D. Alongside medicines B. Registration certificate E. By their Anatomical Therapeutic Chemical C. Certificate of compliance with hygiene Classification regulations D. Sanitary-epidemiological certificate 36. A pharmacy provides certain categories E. Sanitary passport of ill persons with medicines free of charge or at a reduced price. What conditions allow 30. How long should a retail business free of charge supply of out-patients with that deals in medicines keep the quality necessary medicines? Органiзацiя та економiка фармацiї 21

41. Under the current legislation there is A. Diabetes mellitus a certain list of controlled substances that B. Headache require keeping of the special inventory log. C. Cold Select the drug that belongs on this list: D. Muscle pain E. Cuts and abrasions A. Phenobarbital B. Novocaine 37. Medicinal dyes should be stored in a C. Solpadeine special cabinet. Which of the listed medical D. Digoxin products is a dye: E. Analgin (Metamizole) A. Brilliant green 42. Bank is a financial mediator in B. Hydrogen peroxide pharmacy’s payments. Payment of taxes C. Ethyl alcohol withheld from the employees’ salary into the D. Glucose budget requires the following document: E. Ascorbic acid A. Payment order 38. To re p l e n i s h i t s fixed assets, the pharmacy B. Check payable in account made a decision to arrange a credit with C. Accounting form the trading bank. What document must be D. Cash register receipt concluded in writing between the creditor E. Cash order and the debtor in this case? 43. A system of indicators characterizes A. Credit contract financial and businesss activity of an B. Full material liability contract organization and the state of its assets and C. License sources on the certain day in the monetary D. Balance sheet unit. Name this system: E. Auditor’s conclusion A. Balance sheet 39. A pharmacy supplies the surgical ward B. Business transactions log book of a hospital. What document enables the C. Double entry dispensing chemist to supply the goods: D. Turnover balance sheet E. Receipts and expenditures report A. Purchase order B. Product revaluation notice 44. According to the current Ukrainian C. Report on the movement of packaging legislation all drugs are divided into two D. Consolidated register categories: prescription and nonprescription E. Receipt log book (over-the-counter). Which one of the listed 40. According to the law regulating labour drugs requires no prescription? remuneration, the businesses must establish A. Ascorbic acid, 500 mg №30 their compensation plan in the following B. Tramadol, capsules, 0,05 №10 document: C. Clonidine, ampoules, 1 ml of 0,01% A. Collective agreement solution №10 B. Contract of delivery D. Phenobarbital, tablets, 100 mg №6 C. Decree E. Ketamine, 5% infusion solution, 2 ml №10 D. Statement E. Job description Менеджмент та маркетинг у фармацiї 22

1. A pharmaceutical company focuses on A. Multichannel selling a diverse range of products covering B. Horizontal different customer groups and regions. What C. Corporate kind of organizational structure is typical for D. Contractual such company? E. Administered A. Divisional 7. One of the most important market B. Bureaucratic characteristics is a goods economic trend. C. Functional What economic trend can be characterized by D. Centralized relative stability of high prices and the highest E. Decentralized activity of manufacturers and customers? 2. A pharmacist has a labour dispute with the A. High (stable) pharmacy administration about rescheduling B. Subsiding his annual vacation leave. The employee can C. Downward appeal against the decision of the pharmacy D. Sluggish administration to the following body: E. Low A. Labour disputes committee (LDC) 8. The market can be characterized by the B. Trade union committee following conditions: there are many sellers C. Highest management bodies of and buyers, who have no influence over pharmaceutical service at the regional level current prices; similar and interchangeable D. The Ministry of Public Health of Ukraine competing goods are available; there are no E. Commercial court price limits. What type of market is it? 3. What concept can be described as ”...an A. Pure competition area of exchange with its characteristic B. Monopolistic competition system of economic relations between goods C. Oligopoly manufacturers and consumers”? D. Pure monopoly E. Economic planning A. Market B. Marketing 9. Manufacturer’s marketing department C. Sales detected negative demand for a certain goods. D. Agreement What would be the marketing task? What E. Management type of marketing should be applied? 4. Collective labour agreement is concluded A. Demand making, conversion marketing by a trade union committee with the business B. Demand leveling, synchromarketing owner on behalf of the workforce. Any C. Demand increase, remarketing collective agreement is worked out in written D. Demand decrease, demarketing form. Which article of the Labour Code E. Demand stimulation, promotional regulates the duration of the collective marketing agreement? 10. Highly convincing approach to informing A. 17 the population about the company and its B. 36 products, commercial promotion of high use C. 38 value of the goods and proper conduct of D. 40 business by the company, actions intended to E. 41 prompt purchase of goods by both active and potential customers are all characteristic of: 5. A set of values, traditions, behavioral norms, and views inherent to an organisation A. Adverticement characterizes its following feature: B. Trademark C. Marketing A. Culture D. Communications B. Success E. Supply C. Profitability D. Capitalization level 11. A process dealing with drawing the E. Self-development capability documents, their processing, circulation and storage is called records management. If all 6. For better coverage of various markets documents circulate through one organisation the ”Lubnyfarm” company sells a portion center, - office desk, - then such system of of its production through its own chain of records management is called: pharmacies, another portion is being sold through distributors, and the third - through pharmacies of another business owners. What marketing system of distribution is applied by this company? Менеджмент та маркетинг у фармацiї 23

A. Centralized A. Authoritarian B. Decentralized B. Democratic C. Mixed C. Collective D. Referent D. Liberal E. Specialized E. Direct 12. A pharmaceutical manufacturer sets the 17. Number of mediators that pharmaceutical priceforadrugbasingonitsprimecostwith goods pass on their way from manufacturer to premium. What model of pricing is it? consumer is called: A. Cost-based A. Length of distribution channel B. Competitive B. Level of distribution channel C. Demand-based C. Width of distribution channel D. Supply-based D. Volume of distribution channel E. Breakeven E. - 13. Lately the ”Phytopharm” pharmaceutical 18. To increase its sales, the ”Have a good company has been forced to decrease its day!” pharmacy introduced a discount system. production volume and range of goods. According to this system if a customer Not only does the company head manager buys 100 UAH worth of medical products, demonstrate no managerial abilities, but he this customer receives 2% discount. What also appears to be completely disinterested in marketing communication has this pharmacy the running of the business and executes no implemented? control over it. Determine the leadership type of the head manager in this case: A. Consumer-oriented sales promotion B. Middlemen-oriented sales promotion A. Liberal C. Personal sale B. Democratic D. Public relations, sponsorship C. Directive E. Salesmen-oriented sales promotion D. Authoritarian E. Autocratic 19. A pharmacy offers to its customers a chance to measure their blood pressure. What 14. The ”Medpharm” wholesale pharmaceutical type of goods is it? firm employs a system that encourages its managers to achieve better results in sales A. Service by assigning them points for surpassing B. Convenience goods their sale goals. The points then become C. Nondurable goods converted into material remuneration. This D. Specialty goods way the company management carries out the E. Unsought goods following management function: 20. Several independent mediators work in A. Motivation resale of medical equipment. What group of B. Organization mediators includes persons and legal entities C. Control that specialize in sales of durable goods that D. Delegation require considerabe after-sales service? E. Planning A. Dealer 15. To retain full control over its trade B. Broker operations on the regional market, the C. Commission agent ”Fitoprom” pharmaceutical company D. Consignee conducts its marketing policy without any E. Agent intermediate parties. Name the marketing practice that excludes the middleman: 21. A pharmaceutical company has divided its customers into groups based on their gender, A. Direct age, and size of their families. What approach B. Combined to market segmentation is the basis of this C. Mixed customer division? D. Mediated E. Indirect A. Demographic B. Geographic 16. A certain management style can be C. Socioeconomic characterized by the following features: the D. Psychographic authority is highly centralized; work duties of E. Behavioral the employees are very structured; the ability of employees to make decisions is extremely 22. To decrease business risks, a limited; strict compliance with numerous pharmaceutical company decided to expand rules and regulations is prioritized. Name this its activity and penetrate into new market (to management style: open a fitness center). Name this process: Менеджмент та маркетинг у фармацiї 24

A. Diversification What marketing concept is chosen by this B. Intensification manufacturer in relations with its customers? C. Conglomeration D. Modernization A. Socio-ethical marketing E. Integration B. Product development C. Intensification of commercial effort 23. Hierarchic structure of the Agapetus D. Production development pharmacy management foresees that E. Integrated marketing authority is being passed on directly from the pharmacy manager to the employees. Specify 29. Publicly-owned ”Isotope” factory is the this type of authority: only manufacturer of radiopharmaceuticals in Ukraine. What type of distribution is A. Line characteristic of radioactive drugs? B. Functional C. Line and staff A. Exclusive D. Divisional B. Selective E. Matrix C. Intensive D. Sample 24. A pharmacist approached the chief E. Bulk manager of the pharmacy with a request for pay raise. The chief manager turned down this 30. A pharmaceutical company plans to request. What type of conflict is it? introduce traditional herbal remedies to new markets. What marketing opportunity A. Interpersonal conflict according to Ansoff Matrix was used by the B. Intrapersonal conflict company? C. Dysfunctional conflict D. Intergroup conflict A. Market development E. Conflict between individual and group B. Market penetration C. Product development 25. Product sales manager of a pharmaceutical D. Diversification company was tasked with sales program E. Consolidation inspection and given 10 days to complete this task. The manager completed this task 31. Calendula Ointment is placed on the shelf within 5 days and expects to be rewarded next to Dr. Theiss Calendula Ointment.What with a bonus. What theory of achievement approach to the shelf layout is used in this motivation is based on expectation of a pharmacy? certain event? A. Among competitors A. Vroom’s expectancy theory B. Corporate block layout B. Maslow’s hierarchy of needs C. By package size C. Herzberg’s two-factor theory D. Doubling product facings D. McClelland’s theory of needs E. Seasonality E. McGregor’s Theory X and Theory Y 32. The chief manager of a pharmacy 26. The management plans to open a new designs its organizational structure and pharmacy in one of the local villages. Such job descriptions for its employees. These activity can be identified as: arrangements belong to the following management method: A. Growth strategy B. Vertical integration A. Organizational C. Horizontal integration B. Economic D. Conglomerate diversification C. Legal E. Horizontal diversification D. Simulation E. Psychosocial 27. To minimize business risks, the board of directors of a pharmaceutical company 33. Strategic planning of pharmaceutical decides to expand into a market of plant companies consists of several consecutive protection products. Such approach to risk stages. What stage is the final one? management is called: A. Strategy assessment A. Diversification B. Setting goals and tasks B. Insurance C. Environment assessment and analysis C. Intensification D. Analysis of organisation’s internal strength D. Integration and weaknesses E. Consolidation E. Choice of strategy 28. According to ecological survey, a certain 34. A pharmacist approached the chief pharmaceutical manufacturer holds the first manager of the pharmacy with a proposition place among the local ”green” industries. to introduce an additional service for their Менеджмент та маркетинг у фармацiї 25 customers - blood pressure measurement. 39. What variable of the internal environment What type of communication is it? of the ”Provisor” pharmacy can be described as the ways of transformation of component A. Vertical ascending materials (medicinal agents "an gross") into B. Vertical descending end product (various dosage forms)? C. External D. Intra-level A. Technologies E. Horizontal B. Mission C. Ta s k s 35. A manager of a wholesale pharmaceutical D. Structure company is responsible for relaying various E. Human resources tasks to the employees and supervises the fulfillment of assigned tasks. What 40. The documents of a pharmaceutical management level corresponds with these company are being received and sent in duties? a centralized manner; the documents are stored, drawn-up, registered, and assembled A. Technical into cases both in the Office Desk of the B. Administrative company and the company’s divisions. Specify C. Institutional this type of records management system: D. Top-level E. Middle-level A. Mixed B. Centralized 36. A ”Sunrise” pharmacy chain has changed C. Decentralized the placement of medical products on its D. Referent shelves and in the shop windows, to study E. - what effect would this merchandising tactics have on the sales amount. What method of 41. Employees of a wholesale pharmaceutical marketing research was used by this pharmacy company have undergone an assessment for chain? their compliance with the requirements of their respective positions. Specify the type of A. Experiment human resources assessment: B. Panel C. Survey A. Concluding D. Observation B. Preliminary E. - C. Concurrent D. Financial 37. A pharmaceutical company lowered E. - its price for a certain drug due to strong competition and decreasing demand for this 42. In the process of pharmaceutical company drug. What is the purpose of such price entering an offshore market the traditions policy? and customs, religion, system of values, and education level of the local population A. To ensure business survival were analyzed. What factors of international B. To maximize profits marketing environment were researched? C. Tocreate the image of high-quality medicine manufacturer A. Sociocultural D. To gain leadership due to high quality of B. Political manufactured medicines C. Economic E. - D. Legal E. Technological 38. What activity of a pharmaceutical company includes improvement of 43. What means of demand stimulation can be employees’ working and living conditions, applied by pharmacy management among its healthcare and medical insurance and other employees? means of social development? A. Bonuses A. Social responsibility B. In-store advertising B. Commercial activity C. Layout of medical products in shop- C. Financial activity windows and on shelves D. Industrial activity D. Coupons E. Charity E. - Клiнiчна фармацiя 26

1. A patient suffering from bronchial A. Nitrates asthma was diagnosed with essential B. β-adrenergic blockers hypertension. What antihypertensive drug C. Calcium antagonists is contraindicated for this patient? D. Anticoagulants E. Statins A. Propranolol B. Captopril 7. What hypotensive drug is an agent C. Amlodipine of choice for the patients suffering from D. Hypothiazid (Hydrochlorothiazide) arterial hypertension with concomitant type E. Verapamil I diabetes mellitus? 2. A pharmacy customer complains of A. Lisinopril constricting retrosternal pain that irradiates B. Hydrochlorothiazide into the left arm; he fears that he may die. C. Atenolol The pain appeared suddenly after physical D. Labetalol exertion. Name the first aid medicine in this E. Carvedilol case: 8. A 25-year-old man is diagnosed with acute A. Nitroglycerine pyelonephritis of moderate severity. What B. Metacycline drugs should be prescribed for etiotropic C. Naphthyzin (Naphazoline) therapy? D. Panangin A. Antimicrobial agents E. Riboxin (Inosine) B. Glucocorticoids 3. To treat iron-deficiency anemia the C. Nonsteroidal anti-inflammatory drugs following drug is usually prescribed: D. Anticholinesterase drugs E. Antiarrhythmic drugs A. Ferroplex 9. A 53-year-old woman suffers from B. Furagin (Furazidinum) ischemic heart disease and angina pectoris. C. Corticosteroids Whatdrugcanbeusedtostopangina D. Heparin pectoris attacks? E. Vicasol (Menadione) A. Nitroglycerine 4. A 45-year-old man has been taking B. Drotaverine hydrochloride long-acting nitrates twice a day for a year. C. Propranolol Currently a decrease in effectiveness of the D. Dipiridamol pharmacotherapy is being observed. What E. Acetylsalicylic acid side-effect can be suspected in the first place? 10. A patient is 20 years old. After she was stung by a bee the patient developed A. Development of nitrate tolerance Quincke’s disease; rash in the form of B. Progressing ischemic heart disease blisters and papulae appeared on her torso. C. Progressing coronary atherosclerosis First aid in this case should start with D. Myocardial infarction administering the following drug: E. Impairment of coronary circulation A. Prednisolone 5. A 43-year-old patient was delivered to B. Penicillin an admission room with renal colic attack. C. Freshfrozenplasma What group of drugs would be the most D. Rheopolyglukin (Dextran) effective during the attack? E. Haemodes A. Antispasmodics 11. A patient developed dry cough while B. Hepatoprotectors undergoing pharmacotherapy for arterial C. Antacids hypertension. What group of drugs can be D. Antibiotics characterized by this side effect? E. Cholagogues A. ACE inhibitors 6. A 63-year-old man suffering from B. Calcium antagonists ischemic heart disease was diagnosed with C. Antipsychotics angle closure glaucoma. What group of D. Tranquilizers drugs is CONTRAINDICATED in this E. Antacids case? 12. During an asphyxiating attack the patient with bronchial asthma was given intravenously a drug that caused nausea, headache, excitation, and palpitations as Клiнiчна фармацiя 27 side effects. What drug can cause such acetylsalicylic acid for antiaggregatory reaction? effect: A. Euphylline (Aminophylline) A. 100 mg B. Prednisolone B. 200 mg C. Ambroxol C. 300 mg D. Suprastin (Chloropyramine) D. 400 mg E. Papaverine hydrochloride E. 500 mg 13. A man with gastric ulcer is prescribed 19. Genetically induced adverse reaction to anti-Helicobacter pylori therapy. On the 3rd a certain drug is caused by various enzyme day the patient developed black coloring of defects. Name this reaction: feces. What had caused such changes? A. Idiosyncrasy A. Bismuth subcitrate B. Withdrawal syndrome B. Omeprazole C. Steal syndrome C. Metronidazole D. Rebound effect D. Tetracycline E. Dysbiosis E. Tinidazole 20. A 25-year-old woman is in the 14. A 46-year-old pharmacy customer third trimester of her pregnancy. During suffers from chronic bronchitis and needs a her regular examination, US detected medicine to facilitate expectoration of thick a malformation in the fetus. Medical viscous sputum. What drug is indicated in history of the patient shows that she was this case? taking large doses of diazepam without prescription during her pregnancy. What A. Ambroxol type of side effect has occurred in this case? B. Oxeladin C. Salbutamol A. Teratogenic D. Butamirate B. Embryotoxic E. Codeine phosphate C. Fetotoxic D. Carcinogenic 15. A 52-year-old patient has been E. Mutagenic diagnosed with gouty arthritis, phase 2. What drug should be basic in treatment of 21. A 43-year-old woman has come to this patient? a pharmacy with complaints of sharp headache in the occipital area, palpitations, A. Allopurinol ”visual snow” in her eyes, nausea; her B. Hydrochlorothiazide BP is 180/110 mm Hg. These symptoms C. Paracetamol correspond with: D. Furosemide E. Penicillin A. Hypertensic crisis B. Migraine attack 16. A 3-year-old child is intolerant to C. Exertional angina pectoris attack paracetamol. What antipyretic drug can be D. Cervical osteochondrosis taken instead? E. Acute conjunctivitis A. Ibuprofen 22. A patient, who has undergone treatment B. Acetylsalicylic acid for community-acquired pneumonia, C. Nimesulide complains of hearing impairment. What D. Naproxen antibacterial drug could result in such a side- E. Diclofenac sodium effect? 17. A patient with angina pectoris takes A. Gentamicin long-acting nitrates. Consult him what side- B. Amoxicillin/clavulanate effect is the most common for these drugs: C. Cefazolin D. Ciprofloxacin A. Headache E. Clarithromycin B. Nausea C. Vomiting 23. A 36-year-old woman with herpetic D. Diarrhea rash on her lips has come to a pharmacy. E. Constipation Recommend her a drug for topical treatment: 18. A 60-year-old patient, who had suffered a myocardial infarction, was prescribed acetylsalicylic acid as an antiaggregant. Specify the optimal daily dosage of Клiнiчна фармацiя 28

A. Acyclovir subcutaneous hematomas. What medicine B. Fluconazole should be prescribed as an antidote in this C. Levofloxacin case? D. Metronidazole E. Amikacin A. Protamine sulfate B. Vicasol (Menadione) 24. A woman with open tuberculosis C. Streptokinase is undergoing in-patient treatment in D. Clopidogrel the tuberculosis clinic. What drug was E. Acetylsalicylic acid prescribed by her physician for etiotropic treatment? 30. A young mother has come to a pharmacy to buy an antipyretic drug for her 3-month- A. Isoniazid old infant. What dosage form would you B. Acyclovir choose for the infant? C. Metronidazole D. Doxycycline hydrochloride A. Suppositories E. Benzylpenicillin (Penicillin G) B. Ta b l e t s C. Capsules 25. A patient has been receiving palliative D. Spray treatment with morphine hydrochloride E. Lozenges for a week. Following that the patient demands continuation of this treatment. 31. A 74-year-old man came to the What phenomenon has occurred in this pharmacy. He had been prescribed case? ampicillin for antibiotic treatment of dysenteric gastroenterocolitis. What group A. Dependence of drugs should be recommended for B. To l e r a n c e dysbiosis prevention in this case? C. Cumulation D. Potentiation A. Probiotics E. Summation B. Antacids C. Enzymatic agents 26. A 65-year-old man with community- D. Sorbents acquired pneumonia was prescribed E. Immunosuppressants antibiotic agent amikacin. It should be kept in mind, that amikacin has the following 32. A 28-year-old woman came to a side-effect: pharmacy complaining of constipation that developed after antacid treatment. What A. Ototoxicity drug could be the cause of this symptom? B. Red coloring of urine C. Vomiting A. Aluminium-containing drugs D. Increased blood pressure B. Magnesium-containing drugs E. Decreased blood pressure C. Calcium carbonate D. Simethicone 27. Several cholesterol gallstones are E. Ranitidine detected in the gallbladder of a woman. Choose the drug to dissolve and excrete the 33. What antacid can cause constipations, stones: osteoporosis, and encephalopathy when taken for a long period of time? A. Ursodeoxycholic acid B. Papaverine A. Aluminium hydroxide C. Domperidone B. Sodium bicarbonate D. Loperamide C. Calcium carbonate E. Platyphyllin D. Sodium alginate E. Magnesium oxide 28. During anti-Helicobacter quadrotherapy patient’s feces colored black. What drug 34. A 60-year-old man has come could have caused this effect? to a pharmacy with complaints of impaired twilight vision, dry sclera, A. Bismuth subcitrate cracked and peeling skin. The dispensing B. Omeprazole chemist suspected hypovitaminosis and C. Amoxicillin recommended the customer to take the D. Clarithromycin following drug after consultation with the E. Metronidazole physician: 29. A patient receives heparin for acute myocardial infarction. On the third day the patient developed hematuria and Клiнiчна фармацiя 29

A. Retinol acetate should be taken separately with 2-hour B. Tocopherol acetate interval in between. Simultaneous taking of C. Ergocalciferol both drugs: D. Vicasol (Menadione) E. Ascorbic acid A. Decreases ofloxacin absorption B. Increases ofloxacin absorption 35. A patient with arterial hypertension, C. Increases antacid effectiveness who takes captopril, was prescribed a D. Decreases antacid effectiveness potassium-sparing diuretic, spironolactone. E. Increases risk of dysbiosis What complication can develop in the patient due to this combination of drugs? 40. A 54-year-old hypertonic patient undergoing pharmacotherapy developed A. Hyperkalemia bronchial spasm. His physician considers B. Hypocalcemia it to be a therapy-induced complication C. Hyponatremia caused by the drug that belongs to the D. Hypoglycemia following group: E. Hypernatremia A. β-adrenergic blockers 36. A patient was prescribed an oral B. Calcium antagonists antibiotic for treatment and an antacid to C. α-adrenergic blockers remove heartburn symptoms. If the drugs D. Ganglionic blockers are taken simultaneously their interaction E. Diuretics can result in the following: 41. A patient with chronic heart failure, A. Antibiotic malabsorption who has been taking cardiac glycosides, B. Relative overdosage developed signs of glycoside intoxication. C. Inhibition of hepatic microsomal enzymes What antidote would be advisable in this D. Mutual potentiation case? E. Acceleration of metabolism and excretion A. Unithiol (DMPS) 37. A 63-year-old woman suffering from B. Vicasol (Menadione) diabetic nephropathy with functional C. Protamine disturbance of the kidneys needs etiotropic D. Naloxone treatment for focal pneumonia. What drug E. Methionine is CONTRAINDICATED in this case? 42. For treatment of enteric infection a 36- A. Aminoglycosides year-old woman was prescribed a nitrofuran B. Natural penicillins derivative that is poorly absorbed in the C. Synthetic penicillins intestine and takes its effect along the D. Macrolides intestinal tract. Name this drug: E. Combined penicillins A. Nifuroxazide 38. A 68-year-old man has been prescribed B. Furacilin (Nitrofural) a hypolipidemic agent as a part of his C. Nitroxoline combination therapy for ischemic heart D. Furadonin (Nitrofurantoin) disease. Name this drug: E. Nalidixic acid A. Atorvastatin 43. Specify the drugs recommended for B. Nitroglycerine prevention and correction of dysbiotic C. Lisinopril problems caused by antibiotic therapy: D. Nifedipine E. Hydrochlorothiazide A. Probiotics B. Antacids 39. When dispensing an antacid agent and C. Prokinetics ofloxacin in tablets, the dispensing chemist D. Uroseptics warned the customer that these drugs E. Choleretics