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Krok 2. Pharmacy

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Krok 2. Pharmacy Sample test questions Krok 2 Pharmacy () Фармацевтична хiмiя 2 1. An analyst of a chemical laboratory A. Ammonium oxalate had received a glucose substance for B. Magnesium sulfate analysis. To check its quality he used a C. Potassium chloride polarimeter. The analyst measured: D. Sodium nitrite E. Ammonium molybdate A. Angle of rotation B. Refractive index 7. Optical rotation angle of substances is C. Optical density determined under the temperature of 20oC, D. Melting point in 1-decimeter-thick layer, with wavelength E. Specificgravity of sodium spectrum D-lines (λ = 589.3 nm), and is calculated with reference to a solution 2. The analytical laboratory received containing 1 g of the substance per ml. It is calcium chloride. What volumetric called: solution should be used for quantitative determination of this medicinal substance? A. Specific optical rotation B. Optical density A. Sodium edetate C. Refractive index B. Potassium bromate D. Relative density C. Hydrochloric acid E. Distribution coefficient D. Potassium permanganate E. Sodium hydroxide 8. Which of the following antibiotics can be identified by means of maltol test? 3. An analytical chemist of a central industrial laboratory performs quantitative A. Streptomycin sulfate determination of penicillin sum in B. Doxycycline hydrochloride benzylpenicillin sodium salt by means of C. Amoxicillin iodometric method. What indicator is used? D. Lincomycin hydrochloride E. Kanamycin monosulfate A. Starch B. Phenolphthalein 9. A pharmaceutical analyst identifies C. Potassium chromate the substance of potassium acetate. What D. Methyl orange reagent confirms the presence of potassium E. Methyl red cation in the substance? 4. Paracetamol substance has been sent A. Tartaric acid for analysis. Reaction with the solution of B. Sodium hydroxide iron (III) chloride resilted in the blue-violet C. Potassium permanganate coloring. This indicates the presence of: D. Iron (III) chloride E. Zinc oxide A. Phenolic hydroxyl B. Aldehyde group 10. An analytical chemist performs the C. Keto group qualitative assessment of mercury (II) D. Ester group chloride. What method is recommended by E. Alcoholic hydroxyl the State Pharmacopoeia of Ukraine for quantitative assessment in this case? 5. An analytical laboratory has received a procaine hydrochloride substance A. Complexometric titration for analysis. According to the State B. Nitritometric titration Pharmacopoeia of Ukraine limit content of C. Bromatometry heavy metals should be determined with the D. Alkalimetry following reagent: E. Acidimetry A. Thioacetamide 11. An analytical chemist investigates a B. Methoxyphenylacetic acid 3% hydrogen solution. What reagent is C. Hypophosphite recommended by the State Pharmacopoeia D. Aminomethyl alizarin acetic acid of Ukraine for identification of this E. Sulfomolybdenum substance? 6. Chloride of lime is identified by calcium A. Potassium chromate cations after boiling with acetic acid in order B. Sodium chloride to eliminate active chlorine. What reagent is C. Magnesium sulfate used? D. Calcium chloride E. Zinc oxide 12. Benzoic acid is known to have antiseptic properties. Toidentify this acid the following should be used: Фармацевтична хiмiя 3 A. Glutaconic A. FeCl3 B. Gluconic B. [NH4]2C2O4 C. Glutamic C. K2[HgI4] D. Glyoxylic D. K2CrO4 E. Hexanic E. KMnO4 18. What method is recommended by 13. An analytical chemist analyses the the State Pharmacopoeia of Ukraine for substance of racemic menthol according to quantitative determination of potassium the State Pharmacopoeia of Ukraine. To chloride substance that is used in treatment identify the drug and determine its purity he of hypokalemia? measures optical rotation that should occur within the interval: A. Argentometry B. Bromatometry A. From +0.2o to -0.2o C. Iodometry B. From -48o to -51o D. Cerimetry C. From +50o to +56o E. Polarimetry D. From +10o to +13o E. From -102o to -105o 19. During limit test for aluminium admixture, the State Pharmacopoeia of 14. Presence of phenolic hydroxyl in the Ukraine recommends to use the following structure of pyridoxine hydrochloride can solution as the basic reagent: be confirmed by application of the following solution: A. Hydroxyquinoline B. Sodium tetraphenylborate A. Iron (III) cloride C. Thioglycolic acid B. Potassium permanganate D. Sodium hypophosphite C. Sodium sulfate E. Barium chloride D. Silver nitrate E. Sodium nitrite 20. Presence of nitrate radical in metronidazole structure can be confirmed 15. An analytical chemist can quantitatively by reduction of nitrate radical to amino determine the thiamine bromide content in group with production of: powders by means of: A. Azo dye A. Alkalimetry B. Indophenol B. Nitritometric titration C. Thiochrome C. Bromometry D. Iodoform D. Permanganatometry E. Murexide E. Complexometric titration 21. Xycaine quantitative content can be 16. Quantitative content of theophylline can determined by means of argentometry (back be determined by alkalimetric titration of titration). What indicator is required by this nitric acid that is quantitatively obtained as method? the result of the following theophylline salt production: A. Iron (III) ammonium sulphate B. Sodium eosinate A. Silver C. Bromphenol blue B. Potassium D. Starch C. Sodium E. Potassium chromate D. Ammonium E. Lithium 22. An analytical chemist performs quantitative analysis of isoniazid by means 17. In the process of isoniazid identification of direct bromatometry with volumetric a pharmacy analyst thoroughly boiled the solutions of potassium bromate, potassium substance with 2,4-dinitrochlorobenzene. bromide, hydrochloric acid and methyl red The substance turned yellow. After adding as an indicator. This method is based on the alkaline solution the substance turned first following reaction: violet and then brownish-red. As the result of this reaction the following aldehyde derivative is produced: Фармацевтична хiмiя 4 A. Oxidation of the hydrazine group with reagent. If these admixtures are present the bromine substance colors: B. Reduction of the hydrazine residue with bromine A. Red C. Oxidation of the hydrazine residue with B. Blue potassium bromide C. Green D. Opening of the pyridine ring D. Turquoise E. Bromination of the pyridine ring E. White 23. The main method of quantitative 29. The analyst determines quantitative determination of corticosteroids is: content of sodium benzoate by means of acidimetry in non-aqueous medium A. Spectrophotometry according to the State Pharmacopoeia of B. Potentiometry Ukraine. What reagent is used as a solvent C. Cerimetry in this case? D. Argentometry E. Acidimetry A. Anhydrous acetic acid B. Pyridine 24. According to the State Pharmacopoeia C. Concentrated sulfuric acid of Ukraine, an analytical chemist D. Dimethyl formamide determines quantitative content of E. Sulfanilic acid potassium acetate by means of acidimetry in non-aqueous medium. Name the volumetric 30. What antibiotic has beta-lactam cycle in solution in this case: its structure? A. Perchloric acid A. Benzylpenicillin potassium salt B. Iodine B. Doxycycline hyclate C. Potassium bromate C. Chloramphenicol D. Sodium hydroxide D. Streptomycin sulfate E. Sodium nitrite E. Lincomycin hydrochloride 25. The chemical name of 2,2- 31. The chemical name of 2-benzyl-1H- (diphenylmethoxy)-N,N-dimethyl-ethanamine benzimidazole hydrochloride corresponds hydrochloride corresponds with the with the following medicinal substance: following medicinal substance: A. Dibazol (Bendazolum) A. Diphenhydramine hydrochloride B. Omeprazole B. Ethylmorphine hydrochloride C. Indometacin C. Lidocaine hydrochloride D. Phenazepam D. Ciprofloxacin hydrochloride E. Vicasol (Menadione) E. Papaverine hydrochloride 32. Identification of potassium iodide 26. An analytical chemist should use the requires performing an oxidation reaction following solution to identify sodium- in acid medium, which produces free iodine containing substances: that colors chloroform layer. What reagent is used for such a reaction? A. Potassium pyroantimonate B. Potassium permanganate A. Sodium nitrite C. Sodium citrate B. Silver nitrate D. Potassium carbonate C. Barium chloride E. Barium hydroxide D. Sodium carbonate E. Ammonium oxalate 27. An analytical chemist performs collargol identification by means of ashing. Obtained 33. An analytical chemist determines residue is then dissolved in hydrochloric potassium ions admixture in a medicinal acid. Specify the analytical effect that is substance with sodium tetraphenylborate observed in this case: according to the State Pharmacopoeia of Ukraine. What analytical effect would A. White precipitate confirm the presence of this admixture? B. Black precipitate C. Yellow precipitate A. White opalescence D. Blue precipitate B. Yellow coloring E. Light green precipitate C. Blue coloring D. Pink coloring 28. Calcium gluconate is being tested E. Brown coloring for presence of admixtures of saccharose and reducing sugars with copper-tartrate 34. What corticosteroid medicinal substance Фармацевтична хiмiя 5 has two fluorine atoms in its chemical alcohol medium. This drug is: structure? A. Boric acid A. Fluocinolone acetonide B. Benzoic acid B. Dexamethasone C. Salicylic acid C. Triamcinolone acetonide D. Glutaminic acid D. Prednisolone E. Acetylsalicylic acid E. Hydrocortisone acetate 41. Bromatometry allows quantitative 35. A private pharmacy received a supply analysis of the following drug: of a drug with 2.3-dihydro-2-methyl-1.4- naphthoquinone-2-sulfonate sodium as an A. Sodium salicylate active ingredient. Name this drug: B. Glutamic
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