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Pharmaceutical and Veterinary Compounds and Metabolites

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Pharmaceutical and Veterinary Compounds and Metabolites PHARMACEUTICAL AND VETERINARY COMPOUNDS AND METABOLITES High quality reference materials for analytical testing of pharmaceutical and veterinary compounds and metabolites. lgcstandards.com/drehrenstorfer [email protected] LGC Quality | ISO 17034 | ISO/IEC 17025 | ISO 9001 PHARMACEUTICAL AND VETERINARY COMPOUNDS AND METABOLITES What you need to know Pharmaceutical and veterinary medicines are essential for To facilitate the fair trade of food, and to ensure a consistent human and animal welfare, but their use can leave residues and evidence-based approach to consumer protection across in both the food chain and the environment. In a 2019 survey the globe, the Codex Alimentarius Commission (“Codex”) was of EU member states, the European Food Safety Authority established in 1963. Codex is a joint agency of the FAO (Food (EFSA) found that the number one food safety concern was and Agriculture Office of the United Nations) and the WHO the misuse of antibiotics, hormones and steroids in farm (World Health Organisation). It is responsible for producing animals. This is, in part, related to the issue of growing antibiotic and maintaining the Codex Alimentarius: a compendium of resistance in humans as a result of their potential overuse in standards, guidelines and codes of practice relating to food animals. This level of concern and increasing awareness of safety. The legal framework for the authorisation, distribution the risks associated with veterinary residues entering the food and control of Veterinary Medicinal Products (VMPs) varies chain has led to many regulatory bodies increasing surveillance from country to country, but certain common principles activities for pharmaceutical and veterinary residues in food and apply which are described in the Codex guidelines. water supplies. For example, the EU Directive 96/23/EC sets out the requirements for residue monitoring plans and establishes On the following pages you will the range of substances to be tested in live animals and find our extensive selection of animal products. In addition, each EU member state must have a National Residue Control Plan (NRCP). NRCPs are targeted pharmaceutical and veterinary surveillance testing designed to police the correct use of reference materials, including where veterinary medicinal products. Non-EU countries exporting available the parent compounds, food to the EU must implement monitoring programmes which comply with equivalent food safety levels. associated metabolites and stable isotope labelled (SIL) compounds. In China, the Ministry of Agriculture Announcement No. 235 (中华人民共和国农业部公告第235号) sets out the requirements for residue monitoring plans and establishes the range of Visit lgcstandards.com/ substances to be tested in live animals and animal products. drehrenstorfer to explore the The government also sets National Food Safety Inspections full and extensive range of over (国家食品安全监督抽检) every year to police the correct use of veterinary medicinal products to ensure food safety. In 8,000 Dr. Ehrenstorfer reference addition, a new GB method took effect on 1 April, 2020, entitled materials available for food and ‘National food safety standard - Maximum Residue Limits For environmental analysis. Veterinary Drugs in Food’ (‘食品安全国家标准 动物性食品中兽药 最大残留限量 (报批稿)’). 2 Discover our pharmaceutical and veterinary compounds and metabolites range: lgcstandards.com/drehrenstorfer Our Dr. Ehrenstorfer range of pharmaceutical and veterinary We are continually adding products to this portfolio to maintain reference materials has been designed to support you in your pace with emerging and evolving analytical requirements. Our analytical testing and address different regulatory methods latest and full range can always be explored on our website applied around the world. You will find our comprehensive lgcstandards.com. offering includes both metabolites and stable isotope labelled (SIL) compounds for many of our parent compounds. With all measurements on our certificate of analysis carried out in accordance with ISO 17025 and a majority of products Testing the active drug is often not sufficient, since they are produced under the scope of our ISO 17034 accreditation, metabolized into other biologically active substances. As more we guarantee the highest quality reference materials for your research is conducted in this area, metabolites are increasingly analytical testing. being written into regulations with specific maximum residue limits, necessitating metabolite testing. SIL compounds can be added to samples to negate the ‘matrix effects’ often observed with mass spectrometric techniques such as LC-MSMS, further ensuring the reliability of your analysis. what is your smart solution™ ? Challenge us to meet your analyte needs, no matter the complexity. Put us to the test at lgcstandards.com/custom 3 Discover our pharmaceutical and veterinary compounds and metabolites range: lgcstandards.com/drehrenstorfer pharmaceutical and veterinary compounds and metabolites Dr. Ehrenstorfer has an extensive range of neat, single solution and multicomponent solution products for the analytical testing of pharmaceutical and veterinary compounds and metabolites. In addition, we offer not just the parent compounds, but also stable isotope labelled (SIL) compounds, associated metabolites and SIL variants of metabolites for some products. On the following pages you will find an index of selected parent compounds and available associated SILs and metabolites, allowing you to thoroughly test for pharmaceutical and veterinary compounds. You can also visit lgcstandards.com/drehrenstorfer to browse the full range of products. Product code Description Pack CAS number SIL Metabolite SIL of size Metabolite DRE-C10006000 Aceclofenac 50mg 89796-99-6 NEW DRE-C10008000 Acenocoumarol 10mg 152-72-7 NEW DRE-C10010290 Acepromazine hydrochloride 10mg 973-12-6 DRE-C10010300 Acezpromazine maleate 100mg 3598-37-6 DRE-C10010320 Acepromazine D6 maleate 10mg 1331655-50-5 • DRE-C10011900 4-Acetylaminoantipyrine 100mg 83-15-8 DRE-C10012500 2-Acetamido-5-nitrothiazole 100mg 140-40-9 DRE-C10013700 Acetanilide 100mg 103-84-4 DRE-C10016950 Acetildenafil 10mg 831217-01-7 DRE-C10018700 Acetompenaphthone 100mg 573-20-6 NEW DRE-C10023150 N-Acetyl-L-cysteine 25mg 616-91-1 NEW DRE-C10024000 Acetylsalicylic acid 250mg 50-78-2 DRE-C10024050 Acetylsulfamethoxazole 100mg 21312-10-7 DRE-C10024051 Acetylsulfamethoxazole D4 10mg 1215530-54-3 • DRE-C10024500 N-Acetyl-L-tyrosine 100mg 537-55-3 NEW DRE-C10032000 Acitretin 50mg 55079-83-9 NEW DRE-C10045600 Acyclovir 100mg 59277-89-3 DRE-C10045750 Adapalene 50mg 106685-40-9 NEW DRE-C10045805 Adefovir dipivoxil 100mg 142340-99-6 NEW DRE-C10045810 Adenine 100mg 73-24-5 NEW DRE-C10045820 Adenosine 250mg 58-61-7 DRE-C10045850 Adrenochrome semicarbazone 100mg 69-81-8 DRE-C10046500 Adonit 100mg 488-81-3 DRE-C10047700 Agaric acid 250mg 666-99-9 DRE-C10049000 Aklomide 100mg 3011-89-0 DRE-C10065000 Albendazole 100mg 54965-21-8 DRE-A10065000AL-100 Albendazole 100 µg/mL in Acetonitrile 1ml 54965-21-8 NEW DRE-C10065020 Albendazole-2-amino 100mg 80983-36-4 • DRE-C10065200 Albendazole-2-aminosulfone 50mg 80983-34-2 • DRE-A10065200AL-100 Albendazole-2-aminosulfone 100 µg/mL in 1ml 80983-34-2 • NEW Acetonitrile 4 Discover our pharmaceutical and veterinary compounds and metabolites range: lgcstandards.com/drehrenstorfer Product code Description Pack CAS number SIL Metabolite SIL of size Metabolite DRE-C10065250 Albendazole-2-aminosulfoxide 50mg 80983-35-3 • DRE-C10065300 Albendazole-sulfone 10mg 75184-71-3 • DRE-A10065300AL-100 Albendazole-sulfone 100 µg/mL in Acetonitrile 1ml 75184-71-3 • NEW DRE-C10065400 Albendazole-sulfoxide 10mg 54029-12-8 • DRE-C10065410 Albendazole-sulfoxide D3 (methyl D3) 10mg 1448346-38-0 • DRE-C12772050 Albendazole-2-aminosulfoxide 10mg 936-05-0 • DRE-XA12772050AC Dimetridazole-2-hydroxy 100 µg/mL in Acetone 1.1ml 936-05-0 • DRE-C12772051 Dimetridazole-2-hydroxy D3 10mg 1015855-78-3 • DRE-C10098000 Allantoin 100mg 97-59-6 DRE-C10118000 Allopurinol 100mg 315-30-0 DRE-C15811500 Oxypurinol 10mg 2465-59-0 • NEW DRE-C10142700 Alprostadil 10mg 745-65-3 NEW DRE-C10144000 Altrenogest 100mg 850-52-2 DRE-A10144000AL-100 Altrenogest 100 µg/mL in Acetonitrile 1ml 850-52-2 NEW DRE-C10146000 Amantadine hydrochloride 100mg 665-66-7 DRE-C10148800 Ambroxol hydrochloride 100mg 23828-92-4 DRE-A10148800AL-100 Ambroxol hydrochloride 100 µg/mL in Acetonitrile 1ml 23828-92-4 NEW DRE-C10148850 Amcinonide 100mg 51022-69-6 DRE-CA10158000 Amidate 100mg 17321-47-0 DRE-C10163900 Amikacin 100mg 37517-28-5 NEW DRE-C10166000 4-Aminoantipyrine 10mg 83-07-8 DRE-C10185000 Aminocaproic acid 100mg 60-32-2 NEW DRE-C10202370 2-Aminoflubendazole 10mg 82050-13-3 DRE-L10202370ME 2-Aminoflubendazole 10 µg/mL in Methanol 10ml 82050-13-3 DRE-C10209400 Aminopentamide 10mg 60-46-8 NEW DRE-C10227010 4-Aminosalicylic acid 100mg 65-49-6 DRE-C10227020 5-Aminosalicylic acid 100mg 89-57-6 DRE-C10227200 Aminotadalafil 25mg 385769-84-6 DRE-C10227220 (R,S)-Aminotadalafil 50mg 1093940-68-1 NEW DRE-C10231000 Amitriptyline hydrochloride 100mg 549-18-8 NEW DRE-C10240500 Amlodipine besylate 100mg 111470-99-6 DRE-C10242500 Amoxicillin trihydrate 250mg 61336-70-7 DRE-A10242500AL-100 Amoxicillin trihydrate 100 µg/mL in Acetonitrile 1ml 61336-70-7 NEW DRE-C10243050 Amphotericin B 100mg 1397-89-3 DRE-C10243080 Ampicillin trihydrate 100mg 7177-48-2 DRE-C10243090 Amprenavir 10mg 161814-49-9 NEW DRE-C10243100 Amprolium hydrochloride 250mg 137-88-2 DRE-C10245500 D-Amygdalin 100mg 29883-15-6 DRE-C10246500 Amylmetacresol
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