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Important mcqs: Must do mcqs from cracks. 

Edema is define as----- accumulation of fluid in the interstitial  tissue spaces and body cavities failure cells------are hemosiderin laden macrophages seen  inchronic pulmonary congestion One of the inherited cause of hypercoagulability ---- mutation in factor V gene and growth prothrombin gene are the most  common The most dominant histologic characteristic of infarction is  ischemic coagulative necrosis  Deficency of gp1b is called---- bernard-souller syndrome Inherited deficency of gpIIb-IIIa results in a bleeding disorder----  glanzmann thrombasthenia Dense or gamma granules ---- contain ADP,ATP ,ionized calcium ,serotonin and epinephrine www.themedicalglobe.com / www.mgElearning.net Page 1 of 5 

 Most common cause of infarction---- Arterial thrombosis  Long bone fractures are the main cause of fat embolism Lines of zahn confirms a . They are alternate layers of  platelets with and Rbcs  Sudden death is majority linked with embolism Major types of --- cardiogenic , hypovolumic ,  septic ,neurogenic and anaphylactic Virchow’s triad include ----- endothelial injury , stasis or tubulent  blood flow and hypercoagulability Infarct------is an area of ischemic necrosis caused by occlusion of either the arterial supply or the venous drainage in a  particular tissue Arterial thrombi------usually occur over ruptured artherosclerotic plaques , less often at sites of other or old surgery Important SEQs: 

Which pathophysiological changes involved in the production of  pulmonary edema in patients of CCF. Give the pathogenesis of  cardiac edema Enlist difference between congestion and hyperemia A 65 year old lady is bedridden due to a cardiac problem.she develops swelling of the right leg.the clinician suspects DVT. define thrombosis. Enumerate 3 important sites where venous

www.themedicalglobe.com / www.mgElearning.net Page 2 of 5  thrombi could be formed.what complications can develop with  an atrial thrombus  What is virchow’s triade. What is recanalization of thrombus  What is pathogenesis of thrombus formation Enlist the possible fates of thrombus  Enumerate the 3 primary abnormalities that lead to a thrombus formation  How are venous thrombi differ from atrial thrombi regarding the vessels affected the color and the size  Give morphological differences between deep venous thrombus  and post-mortem clot Define embolism and its types A 43 year old man was hospitalized due to multiple fractures of long bone in a motorcade accident. He was in stable condition until 33 days later when he develops dyspnea ,tachypnea and  followed by lose of consciousness and death. What is most likely diagnosis . Give the pathogenesis of this condition A 55 year old man suffered from an attack of myocardial infaraction due to thrombotic occlusion of the coronary branch suppling the affected area of myocardium. What is the  mechanism of injury to myocardial fibers in this patient. Describe  the morphology of infarcted area  Give the most common cause of infarction  Difference between red and white infaract Define shock. Major types of shock. Pathogenesis of shock Enumerate the different stages of shock

www.themedicalglobe.com / www.mgElearning.net Page 3 of 5 Important topics 1st priority:    Thrombus  Embolism  Shock Edema 2nHdyperrimoiraiatnyd: congestion    Haemorrhage  Haemostasis Coagulation cascade endothelium

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