Important mcqs: Must do mcqs from cracks. Edema is define as----- accumulation of fluid in the interstitial tissue spaces and body cavities Heart failure cells------ are hemosiderin laden macrophages seen inchronic pulmonary congestion One of the inherited cause of hypercoagulability ---- mutation in factor V gene and growth prothrombin gene are the most common The most dominant histologic characteristic of infarction is ischemic coagulative necrosis Deficency of gp1b is called---- bernard-souller syndrome Inherited deficency of gpIIb-IIIa results in a bleeding disorder---- glanzmann thrombasthenia Dense or gamma granules ---- contain ADP,ATP ,ionized calcium ,serotonin and epinephrine www.themedicalglobe.com / www.mgElearning.net Page 1 of 5 Most common cause of infarction---- Arterial thrombosis Long bone fractures are the main cause of fat embolism Lines of zahn confirms a thrombus. They are alternate layers of platelets with fibrin and Rbcs Sudden death is majority linked with embolism Major types of shock--- cardiogenic , hypovolumic , septic ,neurogenic and anaphylactic Virchow’s triad include ----- endothelial injury , stasis or tubulent blood flow and hypercoagulability Infarct--------- is an area of ischemic necrosis caused by occlusion of either the arterial supply or the venous drainage in a particular tissue Arterial thrombi------- usually occur over ruptured artherosclerotic plaques , less often at sites of other vascular disease or old surgery Important SEQs: Which pathophysiological changes involved in the production of pulmonary edema in patients of CCF. Give the pathogenesis of cardiac edema Enlist difference between congestion and hyperemia A 65 year old lady is bedridden due to a cardiac problem.she develops swelling of the right leg.the clinician suspects DVT. define thrombosis. Enumerate 3 important sites where venous www.themedicalglobe.com / www.mgElearning.net Page 2 of 5 thrombi could be formed.what complications can develop with an atrial thrombus What is virchow’s triade. What is recanalization of thrombus What is pathogenesis of thrombus formation Enlist the possible fates of thrombus Enumerate the 3 primary abnormalities that lead to a thrombus formation How are venous thrombi differ from atrial thrombi regarding the vessels affected the color and the size Give morphological differences between deep venous thrombus and post-mortem clot Define embolism and its types A 43 year old man was hospitalized due to multiple fractures of long bone in a motorcade accident. He was in stable condition until 33 days later when he develops dyspnea ,tachypnea and tachycardia followed by lose of consciousness and death. What is most likely diagnosis . Give the pathogenesis of this condition A 55 year old man suffered from an attack of myocardial infaraction due to thrombotic occlusion of the coronary artery branch suppling the affected area of myocardium. What is the mechanism of injury to myocardial fibers in this patient. Describe the morphology of infarcted area Give the most common cause of infarction Difference between red and white infaract Define shock. Major types of shock. Pathogenesis of shock Enumerate the different stages of shock www.themedicalglobe.com / www.mgElearning.net Page 3 of 5 Important topics 1st priority: Thrombus Embolism Shock Edema 2nHdyperrimoiraiatnyd: congestion Haemorrhage Haemostasis Coagulation cascade endothelium Copyright: Medical Globe 2020 www.themedicalglobe.com / www.mgElearning.net Page 4 of 5 www.themedicalglobe.com / www.mgElearning.net Page 5 of 5.