US 2004O167159A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2004/0167159 A1 DO-Y00 (43) Pub. Date: Aug. 26, 2004

(54) HEMORRHOID THERAPEUTIC Publication Classification TREATMENT (51) Int. Cl." ...... A61K 31/4745; A61K 31/125 (76) Inventor: Young Hee Do-Yoo, Carmichael, CA (52) U.S. Cl...... 514305; 514/692 (US) (57) ABSTRACT Correspondence Address: Mark C. Jacobs A water Solution of a mixture of quinine and camphor in 3033 El Camino Avenue preferably a ratio of 2 parts quinine to 1 part camphor is Sacramento, CA 95821 (US) injected into hemorrhoidal tissue to effectuate a cure of the hemorrhoid. After a period of time, dependent upon the age (21) Appl. No.: 10/374,377 and other aspects of the physical condition of the patient, the hemorrhoid will turn black, shrivel and flake off to yield a (22) Filed: Feb. 26, 2003 clean non-hemorrhoid area Surrounding the anus. US 2004/0167159 A1 Aug. 26, 2004

HEMORRHOD THERAPEUTIC TREATMENT BRIEF DESCRIPTION OF THE FIGURES 0008. There are no FIGURES in this application. FIELD OF THE INVENTION SUMMARY OF THE INVENTION 0001. This invention pertains to a chemical treatment of 0009. A chemical treatment for the permanent relief of body tissue to rid the body of hemorrhoids using a novel hemorrhoids is provided by the chemical composition of this composition. invention. The composition comprises a mixture of Yong Noe, a Chinese herb known to Western man as camphor, BACKGROUND OF THE INVENTION quinine, and distilled water. These two ingredients are ground into powder and dissolved in distilled water. The 0002 Hemorrhoids-a.k.a. piles, consist of a mass composition is then injected by a medical practitioner into formed by the distention of the veins under the mucous the affected area at least once, and perhaps Several times, membrane that lines the anal channel. These veins in essence over a two week period. After a period of time, the hemor lie under the skin that forms the external portion of the anus. rhoidal tissue will turn dark, harden, and flake off leaving the It can be Said that a hemorrhoid is related to varicose veins. skin clear at the site of the former hemorrhoid. A hemorrhoid may develop from an anal infection or from 0010. It is a first object to provide a process for the an increase in intra-abdominal pressure Such as might take chemical removal of hemorrhoids. place during the course of pregnancy or while lifting heavy 0011. It is a second object to provide a chemical compo objects. Hemorrhoids may also arise if one Strains to def Sition that can be injected into the hemorrhoidal tissue and ecate and/or from complications of certain diseases. The cause the hemorrhoid to Shrivel and disappear. weakneSS in the vein's wall permits the defect to develop. Mild hemorrhoids can be removed or may be treated by 0012. It is a third object to provide a procedure to cause Suppositories and/or nonirritating laxatives. Sometimes it is hemorrhoids to disappear within a two to three week period necessary to Surgically remove the hemorrhoid. Subsequent to treatment. 0013. Other objects of the invention will in part be 0003. Many over-the-counter remedies provide short obvious and will in part appear hereinafter. term relief from hemorrhoids. They do not however provide 0014. The invention accordingly comprises the features, permanent relief. This invention relates to a chemical treat properties, and the relation of components of the instant ment to rid the body of hemorrhoid(s), as opposed to composition, and the process of using the composition, Surgery. This invention does provide permanent relief that which are exemplified in the following detailed disclosure, will last for years. and the scope of the application of which will be indicated 0004. This patent application relates to the chemical in the appended claims. composition and process of using these formulations for the 0015 For a fuller understanding of the nature and objects of the invention reference should be made to the following removal of hemorrhoidal tissue. detailed description. 0005 Camphor, whose formula is CHO, is a ketone DESCRIPTION OF THE PREFERRED that occurs naturally in the wood of the camphor tree and is EMBODIMENT known to be useful as a topical application to relieve pain. 0016 Camphor whose Latin name is Cinnamomum cam It has been applied topically as an analgesic and antipruritic. phora, and is Scientifically known as Dryobalanops aro It is well known to use camphor as a rub to treat respiratory matica Gaertn; and quinine (Cinchona) are the two primary diseases that involve mucous inflammations. Other topical ingredients of the formulation of this invention. They are uses and its use as an oral expectorant have also been used together in a water Solution for injection into the documented. irritated hemorrhoidal tissue to cause the hemorrhoid to 0006 Quinine, whose formula is CHNO-3HO, is contract, flake off, and disappear. a white amorphous powder or crystalline alkaloid that is 0017 Applicant, who is an instructor at the Academy of both water and alcohol Soluble. The preparation of quinine Chinese Culture and Health Medicine, is a licensed acu from ground cinchona bark using a lime and hot paraffin oil puncturist and is an OMD, who practices Chinese medicine extraction System followed by a dilute Sulfuric acid treat in this country. She has discovered a water Solution of a ment and neutralization to yield quinine Sulfate, which in Specific ratio of these two ingredients when injected into the turn is treated with ammonia to yield the alkaloid quinine is hemorrhoid, will cause the hemorrhoid to Shrink and disap well known in the art. The use of quinine both orally and pear. topically has been documented. Topically cinchona has been 0018 Chinese medicine books have indicated that qui used as an astringent in eye Solutions to combat infection. Its nine alone can be used as a topical agent for the relief of the bacterial and anesthetic efforts led to it being used early on pain from hemorrhoids, but these books do not indicate that for malaria caused by the bite of the anopheles mosquito, quinine can be used as an injectable Solution to cure a perSon and derivatives of quinine are used in tonic beverages. of hemorrhoids. 0007. In the instant invention, these two ingredients are 0019 Applicant has found that when quinine alone is used neither topically nor orally, but rather as the basis for used as an injectable with water, the results are not effectual. an injectable solution for hemorrhoid relief The formulation The outer Surface hardens, but the interior of the hemorrhoid of this invention is used not just to relieve the pain and is Still very raw and thus painful. The analogy is made to the irritation of hemorrhoids, but to completely rid the body of Searing of a Steak on a very hot pan. The Surface is done, but the hemorrhoid(s). the interior is still red and raw. Camphor, which is only US 2004/0167159 A1 Aug. 26, 2004

slightly soluble in water, is believed to be too much of an pestle to yield a white flaky powder. In the alterative, after irritant to the body to be capable for injection use alone. purchased as a powder, it is ground further to a very fine 0020. Accordingly, to both Chinese and Western medi powder using a mortar and pestle. No determination of cine, there are five types of hemorrhoids. The invention of particle size was made. this application has been found to work and cause full relief 0029. The second ingredient is quinine. This is a bitter in four of five different types of hemorrhoidal tissue. They crystal alkaloid extracted from cinchona bark. It has the are: 1) Internal hemorrhoids; 2) External hemorrhoids; 3) formula CH2N2O. Internal Side of anus hemorrhoids, clumps of hemorrhoids, 0030) The third ingredient is distilled water. The Cam 4) Prolapse of the anus; but not type 5) Anal fistula. The phor and quinine are preferably mixed in a ratio within the reason for the ineffectiveness on the fifth type of hemorrhoid range of 1 part of Camphor to 3 parts of quinine down to 1 is that the anal fistula, which is one of the five types of part of each ingredient prior to dissolving them in the hemorrhoids, can possibly be treated if it has developed near distilled water. The preferred ratio, as determined by experi the anus and has shallow penetration in the Surface skin. mentation is a 1:2 ratio of camphor to quinine. At the 1:2 However, if the anal fistula has developed deep inside the ratio, patients exhibited little pain and relief was achievable skin tissue, penetrating close to the bones or the intestines, in the shortest period of time for any similar case. When treatment is very difficult. Further Studies are necessary to extra quinine was added to the formulation, the patient felt ascertain treatment efficaciously. pain for the week following injection, but not to the degree 0021. If a patient has more than one of the 1-4 types prior to treatment. When less than a 1:1 ratio of dry hemorrhoids, applicant has found it is better to treat only one ingredients were used, the hemorrhoid took more time to area at a time to avoid anxiety in the patient. Shrink and disappear. Also when less than a 1:1 ratio is used, 0022. It has been found that generally after 10-14 days pain was felt by the patient. If less water is used in making have elapsed, after the Second treatment (injection) the the Solution, the weighed out portion will not dissolve. hemorrhoidal area will have disappeared. The treated area 0031. No side effects from these treatments have been first turns black, hardens and then scales and flakes off. No observed, and the composition is not toxic to adjacent skin. Scar tissue is formed and permanent relief is achieved. In The color change observed is that the tissue goes from Sore Some instances, a third treatment generally a week later, has inflamed red, to gray, to black, and then Scales or falls off been needed and in no instance has it taken more than four leaving the Skin clear. During the period Subsequent to weeks to achieve the desired result. injection, pus is secreted from the treated area, which is 0023. Unlike creams or ointments, which give short-term easily removed by Swabbing with alcohol or water to keep pain relief, the treatment of this invention provides perma the treated area clean. This oozing commences within 3-4 nent relief and removal of the hemorrhoidal tissue. days of the first treatment. 0024. In order to ensure efficiency of the treatment, the EXAMPLE 1. patient is advised to refrain from the consumption of alcohol and/or beverages containing alcohol during the period of 0032. A mixture of Yong Noe and quinine in a 1:1 treatment. mixture in an amount of 37.5 grams are divided into 7 equal weight portions. Each portion of the mixture is dissolved in Composition 4 grams of water by placing the composition in a container in boiling water for 3-5 minutes. The composition is a clear 0.025 This patent application relates to the chemical whitish Solution. This Solution is used at room temperature composition comprising an intimate mixture of camphor and as the medicament for the treatment of hemorrhoids as will quinine dissolved in a water Solution, and to the process of be discussed infra. using this formulation for the removal of hemorrhoidal tissue. EXAMPLE 2 0026. In the instant invention, Camphor, whose chemical 0033. A mixture of camphor and quinine in a ratio of 2 formula is CHO, and Quinine, whose chemical formula parts quinine to 1 part camphor was prepared as in Example is CoHNO-3H2O, are the two ingredients both of 1 and dissolved in 4 grams of distilled water to yield an which have been used separately either topically or orally, amount of the composition of this invention for one injec and are now newly combined as the basis for an injectable tion. solution for the permanent relief of hemorrhoids. The for mulation of this invention is used not just to relieve the pain Preferred Formulation and irritation of hemorrhoids, but to completely rid the body of the hemorrhoids. 0034) 1 part camphor and 2 parts of quinine are inti 0.027 Camphor whose scientific name is Cinnamomum mately mixed to yield a composition having 37.5 grams of camphora, and quinine (Cinchona) are two of the primary solids. The composition of 37.5 grams of solids is comprised ingredients of the formulation of this invention. They are of 25 grams of quinine and 12.5 grams of camphor. This used together in a water Solution for injection into the mixture is equally divided and filled into seven different 10 irritated tissue to cause the tissue to contract, flake off, and cc Vials, and 4 cc distilled water is added to each Vial. Vials disappear. containing the composition of quinine, camphor, and the distilled water are heated in the boiling water in a metal 0028 Yong Noe, the first ingredient, is a Korean herb container for 3-5 minutes. After 3-5 minutes of heating, only which in Western culture, is referred to as Camphor. The the dissolved liquid is extracted from each vial and used for Young Noe is harvested, dried and ground with a mortar and the hemorrhoid treatment. US 2004/0167159 A1 Aug. 26, 2004

Mode of Treatment The duration of complete recovery of treatment differs Slightly depending on the patient's age, physical condition, Typical Treatment Session and skin's elasticity. Patients between the ages of 20-40 take 0035) Step 1. An examination of the condition of the approximately 10-14 days whereas patients between the patient is conducted, to determine the patient's health, e.g., ages of 50 and up take approximately 14-21 days on average blood preSSure, pulse, tongue discoloration, etc. The patient to Cure. is then asked to comfortably lie on one side on top of the 0039 Since certain changes maybe made in the described examination table for examination of the hemorrhoid. This composition and the method of using the composition with position makes both the practitioner and the patient feel out departing from the Scope of the invention herein most comfortable. involved, it is intended that all matter contained in the above 0.036 Step 2. After carefully examining the hemor description shall be interpreted as illustrative and not in a rhoid(s), a determination of the condition and the type is limiting Sense. made. When a patient has a few hemorrhoids, treatment of I claim: the most painful one is carried out first, or, the tissue 1. A proceSS for treating human hemorrhoids which com protrusion that a patient complains most about because of prises preparing a water Solution of quinine and camphor, the associated pain is treated first. and injecting the Solution into the hemorrhoidal tissue. 0037 Step 3. After injection into the hemorrhoid protru 2. The process of claim 1, wherein the ingredients are Sion, the impacted area appears to slightly expand and Subjected to heat to achieve maximum Solubility prior to harden, turning a gray or darkish color; however, the change injection. is not consistent. After a single injection, in 3-4 days, the 3. A new composition of matter for the treatment of treated area Starts to ooze. In approximately 7 days, the size human hemorrhoids which comprises a water Solution of of the injected area is reduced, forms clefs, and emits an quinine and camphor. offensive Smell. As a result of the injection, this procedure, 4. The composition of claim 3, wherein the ratio of the treated hemorrhoid shrinks entirely without pain, and quinine to camphor is in the range of 3 parts quinine:1 part Separates from the treated area. A patient is asked to return camphor, to 1 part quinine to 1 part camphor. for follow-ups on a weekly basis until the hemorrhoid is 5. The composition of claim 3, wherein the ratio of completely cured. The skin Surface will, after healing, have quinine to camphor is about 2:1. gone from black and grey, back to the normal skin tone of 6. A composition for Seven injection treatments of human the perSon. hemorrhoids which comprises a ratio 2 parts quinine to 1 part camphor in the amount of 37.5 grams of Solids, dis Efficacy of this Hemorrhoid Medication solved in 28 grams of distilled water, yields 70 cc of 0.038 Applicant would like to draw special attention to solution, each injection being /7th of the total volume of the fact that when an injection of the newly developed Solution. hemorrhoid medication is administered only into the hem 7. The composition of claim 6, wherein each injection orrhoid protrusion. The medication penetrates into the comprises 5.5 grams of dissolved Solids in 4 grams of water. infested or affected area only, and not into Surrounding 8. The process of claim 1, wherein the composition tissue. Therefore, when the infested hemorrhoid protrusion injected has a quinine to camphor ration of 2:1. is filled with this medication, the remnant of the medication Starts to overflow without disturbing the Surrounding tissue.