Datasheet Version: 1.0.0 Revision date: 25 Jul 2021

Ficolin 1 (FCN1) Antibody Catalogue No.:abx005053

Western blot analysis of extracts of various cell lines, using FCN1 antibody (abx005053) at 1/1000 dilution.

Immunohistochemistry of paraffin-embedded human tonsil using FCN1 Antibody (abx005053) at dilution of 1/100 (40x lens).

Immunohistochemistry of paraffin-embedded human brain astrocytoma using FCN1 Antibody (abx005053) at dilution of 1/100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse lung using FCN1 Antibody (abx005053) at dilution of 1/100 (40x lens). For Reference Only

FCN1 Antibody is a Rabbit Polyclonal antibody against FCN1. The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C- type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.

Target: Ficolin 1 (FCN1)

v1.0.0 Abbexa LTD, Cambridge, UK · Phone: +44 (0) 1223 755950 · Fax: +44 (0) 1223 755951 1 of 2 Abbexa LLC, Houston, TX USA · Phone: +1 832 327 7413 Website: www.abbexa.com · Email: [email protected] Datasheet Version: 1.0.0 Revision date: 25 Jul 2021

Clonality: Polyclonal

Reactivity: Human, Mouse, Rat

Tested Applications: WB, IHC

Host: Rabbit

Recommended dilutions: WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.

Conjugation: Unconjugated

Immunogen: Recombinant protein of human FCN1.

Isotype: IgG

Form: Liquid

Purification: Affinity purified.

Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

UniProt Primary AC: O00602 (UniProt, ExPASy)

Gene Symbol: FCN1

GeneID: 2219

KEGG: hsa:2219

String: 9606.ENSP00000360871

Molecular Weight: Calculated MW: 35 kDa Observed MW: 38 kDa Buffer: ForPBS, pH 7.3,Reference 0.02% sodium azide, 50% glycerol. Only

Concentration: > 1 mg/ml

Note: This product is for research use only.

v1.0.0 Abbexa LTD, Cambridge, UK · Phone: +44 (0) 1223 755950 · Fax: +44 (0) 1223 755951 2 of 2 Abbexa LLC, Houston, TX USA · Phone: +1 832 327 7413 Website: www.abbexa.com · Email: [email protected]