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Microplate Selection and Recommended Practices in High-Throughput Screening and Quantitative Biology
NLM Citation: Auld DSPh.D., Coassin PAB.S., Coussens NPPh.D., et al. Microplate Selection and Recommended Practices in High-throughput Screening and Quantitative Biology. 2020 Jun 1. In: Sittampalam GS, Grossman A, Brimacombe K, et al., editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-. Bookshelf URL: https://www.ncbi.nlm.nih.gov/books/ Microplate Selection and Recommended Practices in High-throughput Screening and Quantitative Biology Douglas S. Auld, Ph.D.,1 Peter A. Coassin, B.S.,2 Nathan P. Coussens, Ph.D.,3 Paul Hensley,4 Carleen Klumpp-Thomas,5 Sam Michael,5 G. Sitta Sittampalam, Ph.D.,5 O. Joseph Trask, B.S.,6 Bridget K. Wagner, Ph.D.,7 Jeffrey R. Weidner, Ph.D.,8 Mary Jo Wildey, Ph.D.,9 and Jayme L. Dahlin, M.D., Ph.D. 7,10 Created: June 1, 2020. Abstract High-throughput screening (HTS) can efficiently assay multiple discrete biological reactions using multi-well microplates. The choice of microplate is a crucial yet often overlooked technical decision in HTS and quantitative biology. This chapter reviews key criteria for microplate selection, including: well number, well volume and shape, microplate color, surface treatments/coatings, and considerations for specialized applications such as high-content screening. This chapter then provides important technical advice for microplate handling including mixing, dispensing, incubation, and centrifugation. Special topics are discussed, including microplate surface properties, plate washing, well-to-well contamination, microplate positional effects, well-to-well and inter-lot variability, and troubleshooting. This information and best practices derived from academic, government, and industry screening centers, as well as microplate vendors, should accelerate assay development and enhance assay quality. -
Assessment of Society's Awareness, Acceptance, and Demand for Robotic Wait Staff in Restaurant Operations Jeffrey Parrent Regis University
Regis University ePublications at Regis University All Regis University Theses Summer 2010 Assessment of Society's Awareness, Acceptance, and Demand for Robotic Wait Staff in Restaurant Operations Jeffrey Parrent Regis University Follow this and additional works at: https://epublications.regis.edu/theses Part of the Computer Sciences Commons Recommended Citation Parrent, Jeffrey, "Assessment of Society's Awareness, Acceptance, and Demand for Robotic Wait Staff in Restaurant Operations" (2010). All Regis University Theses. 127. https://epublications.regis.edu/theses/127 This Thesis - Open Access is brought to you for free and open access by ePublications at Regis University. It has been accepted for inclusion in All Regis University Theses by an authorized administrator of ePublications at Regis University. For more information, please contact [email protected]. Regis University College for Professional Studies Graduate Programs Final Project/Thesis Disclaimer Use of the materials available in the Regis University Thesis Collection (“Collection”) is limited and restricted to those users who agree to comply with the following terms of use. Regis University reserves the right to deny access to the Collection to any person who violates these terms of use or who seeks to or does alter, avoid or supersede the functional conditions, restrictions and limitations of the Collection. The site may be used only for lawful purposes. The user is solely responsible for knowing and adhering to any and all applicable laws, rules, and regulations relating or pertaining to use of the Collection. All content in this Collection is owned by and subject to the exclusive control of Regis University and the authors of the materials. -
Towards Robotic Laboratory Automation Plug & Play: The" LAPP
Towards Robotic Laboratory Automation Plug & Play: The \LAPP" Framework Ad´amWolf´ ,∗,y,z David Wolton,{ Josef Trapl,{ Julien Janda,{ Stefan Romeder-Finger,x Thomas Gatternig ,x Jean-Baptiste Farcet ,x P´eter Galambos ,k and K´arolySz´ell k,? yBaxter AG, a Takeda company zDoctoral School of Applied Informatics and Applied Mathematics, Obuda´ University {Takeda Pharmaceuticals International AG, a Takeda company xBaxalta Innovations GmbH, a Takeda company kAntal Bejczy Center for Intelligent Robotics, Obuda´ University ?Alba Regia Technical Faculty, Obuda´ University, H-8000 Sz´ekesfeh´erv´ar,Hungary E-mail: [email protected] arXiv:2106.10129v2 [cs.RO] 26 Aug 2021 1 Abstract Increasing the level of automation in pharmaceutical laboratories and production facilities plays a crucial role in delivering medicine to patients. However, the particular requirements of this field make it challenging to adapt cutting-edge technologies present in other industries. This article provides an overview of relevant approaches and how they can be utilized in the pharmaceutical industry, especially in development labo- ratories. Recent advancements include the application of flexible mobile manipulators capable of handling complex tasks. However, integrating devices from many different vendors into an end-to-end automation system is complicated due to the diversity of interfaces. Therefore, various approaches for standardization are considered in this article, and a concept is proposed for taking them a step further. This concept enables a mobile manipulator with a vision system to \learn" the pose of each device and - utilizing a barcode - fetch interface information from a universal cloud database. This information includes control and communication protocol definitions and a representa- tion of robot actions needed to operate the device. -
Automation and Robotics Are Increasingly Prominent Features in the Laboratory
Automation and robotics are increasingly prominent features in the laboratory. Freeing up scientists to be creative and transforming the working day for many individuals. a brief history 1875 1945 1961 1981 1993 2004 The earliest mention of Little progress was The world’s first Dr Masahide Sasaki Dr Rod Markin at the The NIH and 300 laboratory automation made until the dust industrial robotic arm opened the first fully University of Nebraska leaders in research in the chemical had settled after WW2 for factory automation automated laboratory Medical Center created and government literature is from 18751, when commercially was released by at the Kochi Medical one of the world’s first identified automation that’s 52 years before available automated Unimation, paving the school to make rapid automated clinical lab technology as crucial the first TV was equipment started to way for all automated and accurate blood management systems, in accelerating medical demonstrated!2 become much more robotics to follow. sampling a reality. tying together discovery and complex. Spotting a Others quickly followed computer processing improving health.5 demand, Washington and, within 10 years, with physical robotics. University was the first 72% of Japanese The original to teach students how national university LAB-InterLink system to operate automated hospitals had adopted consisted of multiple equipment. 3 lab automation.1 testing stages along 112 feet of conveyor belts and was capable of full sample prep, testing and archiving.4 state of the market now $ 3.92 -
Laboratory Automation Selection Guide
Laboratory Automation Selection Guide Issue 2 The Equipment Compatibility Program Quality and Compatibility, Only from Corning. Corning Life Sciences maintains a comprehensive equipment compatibility program in which leading equipment manufacturers certify the compatibility of our products with their instruments. This information is continually updated with our new products as well as new instruments. Corning microplates offer compatibility with a wide range of laboratory instrumentation, including microplate readers, microplate washers, liquid handling instruments, automation accessories, and robotic systems. To make it easy to identify the Corning microplates that perform well with your instruments, we’ve assembled an Equipment Reference Guide with the help of manufacturers from throughout the industry. The Guide is available at www.corning.com/lifesciences. To ensure the accuracy of this reference guide, we invited leading manufacturers to test our microplates on their instru- ments using extensive criteria for fit and function. For example, a microplate reader manufacturer would have tested a Corning microplate for proper fit in the microplate carrier, suitable optical performance, and compatibility with all of the instrument’s accessories, including microplate stackers and bar code readers. If the microplate met all criteria, the manufacturer then signed a form certifying that the microplate was tested for fit and function and found compatible with their instrument and all relevant accessories. So you have their assurance as well as ours that the Corning microplates you choose will perform as needed. Please use this Equipment Reference Guide with confidence. Expert assistance is just a telephone call or email away Customer service and technical representatives are available to answer any question – from pricing and product availability to protocols and applications advice. -
NOMENCLATURE in LABORATORY ROBOTICS and AUTOMATION (IUPAC Recommendations 1994)
Pure & Appl. Chern., Vol. 66, No. 3, pp. 609-630, 1994. Printed in Great Britain. @ 1994 IUPAC INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY ANALYTICAL CHEMISTRY DIVISION COMMISSION ON ANALYTICAL NOMENCLATURE* COMMISSION ON GENERAL ASPECTS OF ANALYTICAL CHEMISTRY? NOMENCLATURE IN LABORATORY ROBOTICS AND AUTOMATION (IUPAC Recommendations 1994) Prepared for publication by H. M. (Skip) KINGSTON' and M. L. KINGSTON2 'Department of Chemistry, Duquesne University, Pittsburgh, PA 15282, USA 2Pittsburgh Regional Library Center, Pittsburgh, PA 15221, USA *Membership of the Commission during the period (1987-1989) when this report was being prepared is given hereunder (Note: The Commission ceased to exist after the 35th IUPAC General Assembly, Lund, 1989). Chairman: R. E. Van Grieken (Belgium); Secretary: C. L. Graham (UK); Titular Members: C. A. M. G. Cramers (Netherlands), L. A. Cume (USA), W. Honvitz (USA), D. Klockow (FRG), M. Parkany (Switzerland); Associate Members: L. S. Ettre (USA), D. M. Everaerts (Netherlands), Y.Gohshi (Japan), P. S. Goel (India), H. M. Kingston (USA), G. J. Patriarche (Belgium), D. L. Rabenstein (USA), J. W. Stahl (USA); National Representatives: Magda Ariel (Israel), K. Danzer (GDR), U. L. Haldna (USSR), D. R. Reeves (New Zealand), B. Schreiber (Switzerland), J. Stary (Czechoslovakia), C. Svehla (UK). +Membershipof the Commission during the preparation of this report (1989-93) was as follows: Chairman: 1989-91 F. Ingman (Sweden); 1991-93 W. E. van der Linden (Netherlands); Vice-chairman: 1989-91 R. E. van Grieken (Belgium); Secretary: 1989-91 W. E. van der Linden (Netherlands); Co-Secretary: 1989-91 C. L. Graham (UK); Secretary: 1991-93 C. L. Graham (UK); Titular Members: L. -
Laboratory Robotics: New Opportunities Internal
December 2018 Volume 13 • Number 11 LabManager.com FOSTERING PRODUCTIVITY AT THE BENCH OR IN THE FIELD Internal Communication Laboratory Robotics: New Opportunities Lab Automation Product Resource Guide Follow us on www.genohm.com squad when they do. they happen, and alert your current with industry trends. defenses prevent errors before and is exible so you can stay conguration, and automatic and maintain. It saves you money An arsenal of rules, ags, The right LIMS is easy to set up Reduce Errors Investment workow, everytime. efciently and protect data. tracking samples in every permissions to work more creating digital locations and access with user, role, and group Foil the gambits of chaos by You control the gateways of Protection Visibility Management Capabilities all in a Single Solution, look no further than SLIMS! laboratory needs Sample Management, an Electronic Laboratory Notebook or Workow SLIMS is a digital platform used for managing all information in a laboratory. Whether your They deserve SLIMS Super Power Your Lab is full of heroes Your Lab is full of heroes They deserve SLIMS Super Power SLIMS is a digital platform used for managing all information in a laboratory. Whether your laboratory needs Sample Management, an Electronic Laboratory Notebook or Workow Management Capabilities all in a Single Solution, look no further than SLIMS! Visibility Protection Foil the gambits of chaos by You control the gateways of creating digital locations and access with user, role, and group tracking samples in every permissions to work more workow, everytime. efciently and protect data. Reduce Errors Investment An arsenal of rules, ags, The right LIMS is easy to set up conguration, and automatic and maintain. -
Laboratory Automation and Robotics
Journal of Automatic Chemistry, Vol. 12, No. 6 (November-December 1990), pp. 227-250 The 1990 International Symposium on Laboratory Automation and Robotics The eighth meeting on this subject was held in Bostonfrom 16 September to 19 September 1990, and brought together around 300 delegates mainly from the USA but with a few from other countries. Hosted by Zymark, the conference covered various facets of automation whilst focusing on laboratory robotics. The symposium included a series ofplenary lectures, invited lectures andposter sessions. The highlights were, for this delegate, thejqrst plenary by Glenn Taylor of Shell (on 'Roboticsfuljqll a strategic need') and a visit to the Zymarkfacility where several distinct robotic systems were in evidence. Whilst promoted as robotic systems these exhibits included quite a considerable degree of laboratory automation, especially solution handling. Glen Taylor's plenary session set the meeting off on a high note. He outlined his company's commitment to automation and robotics and described the changes that encouraged this move, and the problems associated with the acceptance by staff etc., prior to introducing it into all applications. We are in a new culture where the focus is on the customer's needs for analysis rather than just for numbers. New demands by regulatory requirements, environmental requirements, pressures from competition and, in the oil business, by a change in crude starting materials, are specc factors which have changed customers' needs. Accurate, cost-effective analyses are now ofparamount importance and these require good quality control, automation and robotics. A vital role for automation is to improve the credibility of analytical results and Dr Taylor suggested that up to 30% of all analytical demands werefor blind duplicates- sent to test the analyst rather than because they were needed. -
Process Automation for Analytical Measurements Providing High Precise Sample Preparation
Process Automation for Analytical Measurements Providing High Precise Sample Preparation in Life Science Applications Dissertation zur Erlangung des akademischen Grades Doktor-Ingenieur (Dr.-Ing.) der Fakultät für Informatik und Elektrotechnik der Universität Rostock Ellen Vorberg eingereicht am 25.02.2015 in Rostock verteidigt am 08.09.2015 in Rostock Supervisors 1. Prof. Dr.-Ing. habil. Kerstin Thurow, University of Rostock, Center for Life Science Automation 2. Prof. Dr.-Ing. Norbert Stoll, University of Rostock, Institute of Automation 3. Prof. Robin A. Felder, Ph.D., University of Virginia, School of Medicine, Department of Pathology, Charlottesville, VA Acknowledgment First of all, I would like to thank Prof. Dr. Kerstin Thurow for her continuous support throughout my PhD studies and dissertation work. I am truly grateful for her advices and suggestions and, moreover, for the excellent laboratory equipment. Furthermore, I would like to extend my thanks to all the staff members of celisca and the Institute of Automation. Especially, I would like to thank Sybille Horn, Dr. Heidi Fleischer, Dr. Thomas Roddelkopf, Lars Woinar, Heiko Engelhardt, Dr. Hui Liu, Dr. Sebastian Neubert, and Dr. Steffen Junginger for technical support. Most importantly, I thank my beloved husband, Mike Vorberg, for his love, support, and encouragement. Table of Contents Table of Contents List of Figures ............................................................................................................................................ i Sources of Figures -
Download Overview of Industrial Process Automation 2Nd Edition
OVERVIEW OF INDUSTRIAL PROCESS AUTOMATION 2ND EDITION DOWNLOAD FREE BOOK K Sharma | --- | --- | --- | 9780128053546 | --- | --- Industrail Automation and Process Control Greg McMillan Greg. Institutional Subscription. Abstract Topics 2 Citations Related Papers. It pushes the ISA test methods and reports. Application Programming Power Supply Systems Input—Output Redundancy Input Data Reliability Enhancement 3. Field Device Considerations E. ISA 95 Standard Customization Emerging Trends Summary 6. Machine Safety Management Industrial robot Autonomous research robot Domestic robot. This book also provides an extensive bibliography to related publications and topic-specific information. Open Access. Some features of the site may not work correctly. Curt Wendt WendtCW cdmsmith. Basic Modules 8. Selected type: Hardcover. Classification of Industrial Processes Safety Systems I have been using your books for years as basic references in my daily work, and I have my own personal short list of books that I always keep on my desk. Fieldbus Communication Integrated Assemblies 8. If you wish to place a tax exempt order please contact us. Sharma is an industrial automation professional by education, qualification, and practice. Nderim Zeqiri, A. Search for books, journals or webpages Research Feed. Asset Management Operator Station Please guide me. Concluding Remarks Utility Processes Summary Appendix A. Data Acquisition and Control Unit: Software 9. Automated attendant Automated guided vehicle Automated highway system Automated pool cleaner Automated reasoning Automated teller machine Automatic painting robotic Pop music automation Robotic lawn mower Telephone switchboard Vending machine. Introduction 9. Features of Operator Station Introduction 4. Overview of Industrial Process Automation 2nd edition Device Integration Shinskey, F. Needs met by Automation 1. You are connected as. -
Working with Laboratory Automation in Synthetic Biology
This thesis has been submitted in fulfilment of the requirements for a postgraduate degree (e.g. PhD, MPhil, DClinPsychol) at the University of Edinburgh. Please note the following terms and conditions of use: This work is protected by copyright and other intellectual property rights, which are retained by the thesis author, unless otherwise stated. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge. This thesis cannot be reproduced or quoted extensively from without first obtaining permission in writing from the author. The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the author. When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given. Amphibious Researchers: working with laboratory automation in synthetic biology Chris Mellingwood PhD University of Edinburgh October 2018 ii I declare that this thesis has been composed solely by myself and that it has not been submitted, in whole or in part, in any previous application for a degree. Except where stated otherwise by reference or acknowledgment, the work presented is entirely my own. Signature: 5 June 2019 iii Acknowledgements I have been fortunate to have incredibly insightful and patient academic mentors willing to share their knowledge and experiences. I am very grateful to my supervisors Jane Calvert, Pablo Schyfter, and Alistair Elfick for their time, generosity, and thoughtful advice. Special thanks also go to Dominic Berry, Emma Frow, Julie and David Morroll for their invaluable support and guidance. -
Autonomous Robots*
Autonomous Robots* Don Berkich 5/29/08 Texas A&M University-Corpus Christi Abstract “Autonomy” enjoys much wider application in robotics than philosophy. Roboticists dub virtually any robot not directly controlled by a human agent “autonomous” regardless of the extent of its behavioral repertoire or the complexity of its control mechanisms. Yet it can be argued that there is an important difference between autonomy as not-directly-controlled and autonomy as self-control. With all due respect to the enormous achievement Mars rovers Spirit and Opportunity represent, in this paper I argue that the roboticists' conception of autonomy is over-broad in the sense that it is too easily achieved, uninteresting, and ultimately not especially useful. I then propose a theory of autonomous agency that capitalizes on the roboticists' insights while capturing the philosophical conception of autonomy as self-rule. I close by describing some of the capacities autonomous agency so construed presupposes and explaining why those capacities make it a serious challenge to achieve while arguing that it is nonetheless an important goal. word count: 3318 1/13 Introduction In a 1986 manuscript Rod Brooks set the path for robotics development by announcing that he wished “to build completely autonomous mobile agents that co-exist in the world with humans, and are seen by those humans as intelligent beings in their own right.” (1999 p. 86) Brooks astutely sided-stepped difficult questions about intelligence and intentionality with the decidedly dennettian phrase, “are seen by”, yet showed not the slightest hesitation in declaring the goal to be autonomous agency. (Dennett 1987) To be sure, the field of situated robotics Brooks arguably initiated has achieved far more than the commercial success of the floor cleaning Roomba: Mars rovers Spirit and Opportunity are particularly spectacular examples.