CD4 Receptor Diversity Represents an Ancient Protection Mechanism Against Primate Lentiviruses
CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses Ronnie M. Russella,b,1, Frederic Bibollet-Ruchea,1, Weimin Liua, Scott Sherrill-Mixa,b, Yingying Lia, Jesse Connella, Dorothy E. Loya,b, Stephanie Trimbolia,b, Andrew G. Smitha, Alexa N. Avittoa, Marcos V. P. Gondima, Lindsey J. Plenderleithc,d, Katherine S. Wetzelb, Ronald G. Collmana,b, Ahidjo Ayoubae, Amandine Estebane, Martine Peeterse, William J. Kohlerf, Richard A. Millerf, Sandrine François-Souquiereg, William M. Switzerh, Vanessa M. Hirschi, Preston A. Marxj,k, Alex K. Piell, Fiona A. Stewartl,m, Alexander V. Georgievn,o, Volker Sommerl, Paco Bertolanip, John A. Hartq, Terese B. Hartq, George M. Shawa,b, Paul M. Sharpc,d, and Beatrice H. Hahna,b,2 aDepartment of Medicine, University of Pennsylvania, Philadelphia, PA 19104; bDepartment of Microbiology, University of Pennsylvania, Philadelphia, PA 19104; cInstitute of Evolutionary Biology, University of Edinburgh, EH9 3FL Edinburgh, United Kingdom; dCentre for Immunity, Infection, and Evolution, University of Edinburgh, EH9 3FL Edinburgh, United Kingdom; eRecherche Translationnelle Appliquée au VIH et aux Maladies Infectieuses, Institut de Recherche pour le Développement, University of Montpellier, INSERM, 34090 Montpellier, France; fDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109; gHepatology and Gastroenterology Unit, University Hospital of Limoges, 87042 Limoges, France; hLaboratory Branch, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention,
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