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Newsworthy Notes December 2018 a MONTHLY PUBLICATION OF Issue No. 313 NEWSWORTHY NOTES December 2018 A MONTHLY PUBLICATION OF ICBII UPDATE ON THE MESSAGE ROAD TO THE CURE ecember: the end of another amazing year all wrapped up Common Link Between Parkinson’s, Alzheimer’s and in Holiday celebrations, merriment, good cheer, New Year’s Schizophrenia Dresolutions, and reflections. Many people take stock and This article focuses on a potential common link related to mark the year as one to remember, forget, celebrate, regret. Each the dysfunctional synaptic plasticity that science associates summary is as unique, personal and individual as we are, but in with neurodegenerative disorders such as Parkinson’s, the end, one year ends, and a new one begins. Alzheimer’s, and schizophrenia. A specific protein implicated How will you remember the year? At PRO, blessed by your in the cognitive decline of Alzheimer’s also appears to appreciation and gratitude, our choice is to reflect on the good play a role in the genetic predisposition to Parkinson’s and we have done, the difference we have made and the change Schizophrenia, meaning that a drug that targets that protein in attitude and circumstance we help bring about with the could potentially treat a variety of neuropsychiatric disorders, resources, counseling, support groups, and education we deliver according to a new study published October 18, 2018, in the to those needing our help. Journal of Molecular Psychiatry. The road seems never ending. Every step takes so much This protein is known as Striatal-Enriched Protein effort, yet as we move forward we must always reflect on our Tyrosine Phosphatase (STEP) and plays an important role PROGRESS; a desperate cry for help answered, a resource shared in the healthy functioning of synapses, the connections with someone in need, answers to a million questions asked by a between brain cells. Excessive amounts of STEP protein new attendee at a support group. Miracles and magic, one and all, are found in the brains of humans and animal models each giving PRO the power and inspiration to greet the new year of Alzheimer’s disease, Parkinson’s disease, fragile X with enthusiasm and excitement. syndrome, and schizophrenia. The increase in STEP We all have much to be grateful for. PRO is grateful for YOU, leads to a disruption of synaptic function and contributes your thoughts, your encouragement, and your constant support. to the cognitive deficits present in these disorders. Together let’s move forward with the strength of our progress and An experimental drug designed to inhibit the STEP PRESIDENT’S PRESIDENT’S the inspiration of all that is possible in the months and years to protein restores cognitive deficits in a mouse model of come. Alzheimer’s disease. The researchers have shown that The ICBII UPDATE ON THE ROAD TO THE CURE is on this page. genetically eliminating STEP or using the drug to inhibit Enjoy other PROvocative and informative news such as: THE STEP activity improves cognitive deficits in a mouse HEALTHY BENEFITS OF GRATITUDE on page 2; HOLY BASIL TO BEAT model that has behavioral features related to symptoms STRESS AND SLEEP BETTER on page 3; 2018 TAX REFORM: ARE of Schizophrenia. Unfortunately, these small molecule YOU PREPARED FOR THE END OF THE YEAR? on page 4, HEALTH drugs stop working after a while as is the case with BENEFITS OF WILD LETTUCE on page 5, and INSPIRATIONAL L-Dopa. LESSONS on page 7. These findings suggest that a STEP inhibitor if Join us in making a difference in your life, or the life of a loved developed, may be the basis of a new drug that can treat one this MONTH. Donate to us by using Amazon.Smile.com and any number of neurodegenerative diseases. choosing PRO as your charity of choice, which costs you nothing. Good News But know that we could never do all that we do without you. We ICB International, Inc. has the technology to develop know we are providing valuable information and support in the inhibitors of STEP protein. The Company plans to start Parkinson’s community, we continue to appreciate your monthly a research program to develop STEP-SMART Molecule or general donations through our safe PayPal donation page at to restore cognition of Alzheimer’s, Parkinson’s, and ParkinsonsResource.org/#modal-donate or by mail to our office in schizophrenia patients and provide these patients a Palm Desert, California. chance to live a normal life. Until next month, REMEMBER the start of Hanukkah on the 2nd WOULD YOU LIKE TO HELP get their drugs to market Pearl Harbor Remembrance Day on the 7th, Winter Solstice on faster? The joy of being a part of this historical event the 21st, Super Saturday on the 22nd, Christmas Day on the 25th can be had by helping ICBII find the funds to bring and the last day of 2018 or the Eve of 2019 on the 31st. Happy these trials to fruition through your investing, and by New Year from all of us at PRO!! The flowers are the Narcissus & finding others with the financial ability and humanitarian Holly, and the Birthstones are Turquoise & Blue Topaz. ALWAYS mindset to accomplish the, until now, impossible. remember to CELEBRATE YOU and PRAY FOR OUR TROOPS! Please contact Jo Rosen at 760-773-5628 or JoRosen@ Love, Parkinsonsresource.org or by contacting ICBII directly through their website ICBII.com/ or by phone 858-455- 9880. IMAGINE the world without Parkinson’s, MSA or President & Founder Alzheimer’s disease. JUST IMAGINE. 2 Issue No. 313 Newsworthy Notes December 2018 Our Wellness Villagers ACUPUNCTURE ELDER LAW ATTORNEYS MASSAGE & BODYWORK – (cont) • Dr. David Shirazi • (CA) Zoran K. Basich • Rehab Specialists • (CA) William R. Remery ANIMAL-ASSISTED THERAPY • (NY) Ronald A. Fatoullah MEDICAL MARIJUANA • Canine Companions • PSA Organica ESTATE PLANNING- LEGAL AROMA THERAPY • (CA) William R. Remery • MEDI-CAL CONSULTING • Renee Gauthier (NY) Ronald A. Fatoullah • Medi-Cal Consulting Services, LLC NEW ASSISTIVE TECHNOLOGY ESTATE PLANNING – FINANCIAL PLANNING MOBILITY PRODUCTS • California Phones • Cypress Wealth Services • In & Out Mobility • LiftUp, Inc BEAUTY FELDENKRAIS METHOD® PRACTITIONERS • Younger By Tonight NEW • LeAnn Brightwell, CM MEDICINE • US World Meds BOXING/EXERCISE FINANCIAL ASSISTANCE • Rock Steady Boxing NEW • The Assistance Fund, Inc NURSING HOME ATTORNEYS Coachella Valley • (CA) Zoran K. Basich GRAPHIC DESIGN / PHOTOGRAPHY CARE FACILITIES NEW • G-Aries Visions OCCUPATIONAL THERAPY • Atria Hacienda • Easy Speech Therapy Center • A&A Home Care Services HEALTHY PRODUCTS • Caleo Bay • Healthy Chocolate PHARMACIES • Wild Blue-Green Algae • Cornerstone Pharmacy CHIROPRACTIC • Nerium Age Defying Formula • Dr. Curtis Buddingh • Protandim Nrf2 PHYSICAL THERAPISTS- TRAINING SPECIALISTS • Life Wave • Arroyo Physical Health CLINICAL TRIALS • New Beginning Physical Therapy • Parexel International HOSPICE CARE • Innergy Therapy Systems • Asclepes • Family Hospice (local) • Rosi Physiotherapy • Gentiva Hospice (regional) • Rehab Specialists DEEP BRAIN STIMULATION • Vitas Healthcare (nationwide) • Easy Speech Therapy Center • Dr. Michel Lévesque INCONTINENCE SUPPLIES PHYSICIANS AND SURGEONS DENTISTS • Geewhiz • Dr. Michel Lévesque CMD/TMJ Dentists • (CA) Dr. George Altuzarra IN HOME CARE PROFESSIONALS • REAL ESTATE • (CA) Dr. Maryam Bakhtiyari Cambrian Homecare • John Sloan Real Estate Group NEW • (CA) Dr. Dwight Jennings • Senior Helpers of the Desert • (CA) Dr. Steven Olmos • A&A Home Care Services • (CA) Dr. David Shirazi • Brightstar Care NEW RESIDENTIAL CARE FACILITIES • (CT) Dr. Patricia A. Richard NEW • AccentCare, Inc • A & A Home Care • (IL) Drs. Ed and Lynn Lipskis • (TX) Dr. Risto Hurme LEGAL-ATTORNEY-LAWYERS SENIOR HOUSING • (VA) Dr. Brendan C. Stack • (CA) Zoran K. Basich • Atria Hacienda • (VA) Dr Jeffrey L. Brown • (CA) William R. Remery, Esq. • (CA) Dr Alice Sun • (NY) Ronald A. Fatoullah SPEECH THERAPY NEW • Easy Speech Therapy Center Sleep Medicine Dentists LSVT LOUD PROGRAM • Bolden Communications • • (CA) Dr. Maryam Bakhtiyari Easy Speech Therapy Center NEW • Bolden Communication, Inc VISION • (CA) Dr. Steven Olmos • Riverside Institute of Vision Rehabilitation • (CA) Dr. David Shirazi Drs. Kohtz & Spurling • (IL) Drs. Ed and Lynn Lipskis LSVT BIG PROGRAM • New Beginning Physical Therapy • (TX) Dr. Risto Hurme • • (VA) Dr. Brendan C. Stack Rosi Physiotherapy • (VA) Jeffrey L. Brown MASSAGE & BODYWORK • (CA) Dr. George Altuzarra • • (CA) Dr. Dwight Jennings Mot’us Floatation & Wellness Center THE HEALTHY BENEFITS OF GRATITUDE activated when we feel gratitude or display acts of kindness. Caleo Bay Alz Special Care Center Research has also proven that gratitude is also addictive, in a We all know that gratitude is a good thing, but here’s a fact positive way. that might surprise you: gratitude is good for your body. In acts of kindness, feelings of gratitude flood our brains The concept is simple; a healthy mind equals a healthy with a chemical called dopamine. When we are truly grateful body. Since kindness lifts our spirits and warms our hearts, for something (or someone), our brains reward us by giving it aids in fighting off, healing and sometimes even curing a us a natural high. Because this feeling is so good, we are plethora of illnesses that ail us. There are many ways to reap motivated to feel it again and become more inclined to give the benefits of gratitude; for example, keeping a gratitude thanks, and also to do good for others. journal, praying, meditating or simply saying how you feel. Believe it or not, something as simple as saying ‘thank you’ Gratitude is good for our brains. The hypothalamus is the can decrease pain as well. Studies have shown that keeping part of our brain that regulates several of our bodily functions a gratitude journal after a surgery or illness increases including appetites, sleep, temperature, metabolism, and motivation to exercise and will speed up the recovery growth. Studies have shown that our hypothalamus is process. cont. on page 6 HOLY BASIL TO BEAT STRESS AND SLEEP BETTER 3 Dr.
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