H OH metabolites OH Article Caulerpa lentillifera (Sea Grapes) Improves Cardiovascular and Metabolic Health of Rats with Diet-Induced Metabolic Syndrome 1, 2,3 2,3 1, Ryan du Preez y , Marwan E. Majzoub , Torsten Thomas , Sunil K. Panchal z and Lindsay Brown 1,4,* 1 Functional Foods Research Group, University of Southern Queensland, Toowoomba, QLD 4350, Australia;
[email protected] (R.d.P.);
[email protected] (S.K.P.) 2 Centre for Marine Science and Innovation, University of New South Wales, Sydney, NSW 2052, Australia;
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[email protected] (T.T.) 3 School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, NSW 2052, Australia 4 School of Health and Wellbeing, University of Southern Queensland, Ipswich, QLD 4305, Australia * Correspondence:
[email protected]; Tel.: +61-7-3812-6366 Current address: School of Health, Medical and Applied Sciences, Central Queensland University, y Rockhampton, QLD 4701, Australia. Current address: School of Science, Western Sydney University, Richmond, NSW 2753, Australia. z Received: 12 October 2020; Accepted: 3 December 2020; Published: 7 December 2020 Abstract: Caulerpa lentillifera (sea grapes) is widely consumed in South-East Asia as a low-energy food with high contents of vitamins and minerals. This study investigated dried sea grapes containing 16.6% insoluble fibre commercially produced in Vietnam as an intervention. We hypothesised that insoluble fibre is the primary metabolite that will reverse diet-induced metabolic syndrome. Male Wistar rats (n = 48) were randomly allocated to four groups in a 16 week protocol.