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HOW TO USE 30°C 13 min. No sample preparation. REVOLUTIONARY Just mix milk and reagents, MILK ANALYSIS PLATFORM then incubate with the EXTENSO BIOSTICK and read. 1. Mix milk and reagents 2. Incubate for 13 minutes into the Extenso Incubator DUO FROM RISK ANALYSIS TO DAILY SCREENING

3. Insert the BIOSTICK in the drawer 4. Tap to start the reading of the DEVICE

RESULTS ON THE EXTENSO DEVICE

EXTENSO is the all-in-one multiplex, fast, easy and automated solution the dairy industry needs to detect the widest range of contaminants in milk. All in the shortest possible time and ANALYSIS THROUGH The EXTENSO Data Manager providing a simple data-processing interface. allows you to store, track and YOUR DATA MANAGER manage your data in your PREVENT ANTIBIOTICS FROM ENDING UP IN THE FOOD CHAIN centralized environment, in the START FROM MONITORING AND... cloud or on premise. Residues of antibiotics in raw milk alters the efficiency of DETERMINE THE ANTIBIOTIC RISK PROFILE industrial processing of cheese or other fermented dairy products preparation. THEN ADOPT A SPECIFIC SCREENING PLAN

Moreover, the extensive use of antibiotics is linked to the emergence of multi-resistant bacteria raising a big challenge CHOOSE YOUR CUSTOM CONFIGURATION for both animal and human health.

CHANNELS BENEFITS AFLA COLI QUINO X TETRA X AZINE X ERYTHRO X SDX TYLO MULTIPLE BETA X GENTA SPIRA Detect more than 100 antibiotic residues and CAP LINCO STREPTO PRODUCT REFERENCES toxins in milk in one single test. CEFA NEO SULFA X EXTENSO ASSAY APP075 APP027 Define your own surveillance plan: check and pay only for the channels EXTENSO DEVICE EXTENSO INCUBATOR DUO corresponding to the contaminants you wish to detect in your sample. • 6 CHANNELS FLEXIBLE • 12 CHANNELS Whether for monitoring or for a release plan, • 17 CHANNELS choose any combination of contaminants to test amongst 131071 possibilities. EXTENSO IS VALIDATED AND CERTIFIED

RAPID Only 13 minutes to get your results. EXTENSO helps you to take immediate action. Reseller Liège Science Park EXT 39/01-10/2018 CONNECTED Rue Louis Plescia, 8 ALTERNATIVE ANALYTICAL METHODS B-4102 Seraing (Ougrée) Remote access, multiple data export options, FOR AGRIBUSINESS BELGIUM full traceability and automated actions. http://nf-validation.afnor.org/en unisensor.be Phone +32 4 252 66 02 [email protected] MKT152-2019-11-29 SENSITIVITY

TEST DETECTION EU-MRL/MRPL in ng/ml - ppb TEST DETECTION EU-MRL/MRPL in ng/ml - ppb FAMILY NAME OF FAMILY NAME OF CHANNEL ID COMPOUNDS DETECTED (ng/mL ; ppb) (codex) CHANNEL ID COMPOUNDS DETECTED (ng/mL ; ppb) (codex) THE COMPOUNDS THE COMPOUNDS [Not validated by ILVO] [US safe level] [Not validated by ILVO] [US safe level]

Aflatoxin-M1 0,4 0,05 [0,5] Difloxacin 16 / AFLA MYCOTOXINS Aflatoxin-B1 [0,2-0,5] / Enofloxacin [<20] /

Melamine 30 1000-2500 Lomefloxacin [<30] / MELAMINE Ammeline 600 / Flumequine 25 50 AZINE Baquiloprim 250 30 Norfloxacin 20 / PYRIMIDINE DERIVATIVES Trimethoprim 200 50 Pefloxacin [<20] /

Amoxicillin 3 4 (4) Orbilfloxacin [>100] /

Ampicillin 4 4 Oxolonic acid 125 /

Benzylpenicillin (Pen G) 2 4 (4) Nalidixic acid 150 /

Phenoxymethylpenicillin (Pen V) 4 / Sarafloxacin 16 n.f.u.

Cloxacillin 12 30 Cinoxacin [<1000] /

Nafcillin 350 30 Fleroxacin [<50] /

BETALACTAMS - Dicloxacillin 8 30 Pipemidic acid Not detected /

PENICILLINS Oxacillin 16 30 Piromidic acid Not detected /

Penethamate [55] 4 Levofloxacin tbd /

Piperacillin [0,5-1] / SDX SULFONAMIDES Sulfadoxine 70 100***

Ticarcillin [10-15] / Spiramycin 80 SPIRA MACROLIDES 200** (200) Aspoxicillin [1-2] / Neospiramycin 90

Sulbactam [100-1000] / Dihydrostreptomycin 150 200 (200) STREPTO AMINOGLYCOSIDES BETA Tazobactam [1000] / Streptomycin 175 200 (200)

BETALACTAMASE INHIBITORS Clavunalic acid Not detected 200 Sulfadiazine 3

Cefalonium 3 20 Sulfamerazin 1

Cefazolin 9 50 Sulfadimethoxine 5

Cefoperazone 3 50 Sulfamethazine (SMTZ) 1

Cefquinome 14 20 Sulfamethoxazol 100

Ceftiofur 8 Sulfaquinoxaline 4 100** (100) BETALACTAMS - Desfuroylceftiofur 60 Sulfamonomethoxin 2

CEPHALOSPORINS Cephapirin 4 Sulfamethoxypyridazin 1 60** Desacetylcephapirin 16 Sulfaethoxypyridazin tbd

Cefacetrile 9 125 Sulfazalasin [115] 100*** SULFONAMIDES Ceftizoxime 200 / SULFA Sulfapyridin 1 (25 for SMTZ)

Cefuroxime 90 50 Sulfacetamide Not detected

Ceftriaxone 6 / Sulfachloropyridazin 8

Chloramphenicol 0,6 n.f.u. (0,3) Sulfaguanidin 7

Chloramphenicol succinate [0,6] / Sulfathiazol 3 CAP PHENICOLS Thiamphenicol [5000] 50 Sulfisoxazol tbd

Florphenicol(amine) [5000] n.f.u. Sulphatroxozole Not detected

BETALACTAMS - Cefalexin 4 100 Sulfamethizole 150 CEFA CEPHALOSPORINS Cefadroxil 4 / Sulfameter 2

COLI POLYMYXINS Colistin 30 50 (50) Sulfamoxol 1

Erythromycin 30 40 DAPSONE Dapsone Not detected n.f.u.

Gamithromycin Not detected n.f.u. Tetracycline (TC) 70 ERYTHRO MACROLIDES 100* (100) Oleandomycin Not detected / 4-epimer of TC Not detected

Roxithromycin 700 / Chlortetracycline (CTC) 25 100* (100) Gentamicin (C1, C1a, C2, C2a) 60 100 (200) 4-epimer of CTC 1000

Kanamycin A Not detected 150 Oxytetracycline (OTC) 40 GENTA AMINOGLYCOSIDES 100* (100) Spectinomycin Not detected 200 4-epimer of OTC 1000

Sisomycin 175 / TETRA TETRACYCLINES Doxycycline 10 n.f.u.

Lincomycin 80 150 (150) Mynocycline [<50] /

LINCO LINCOSAMIDES Clindamycin 40 / Demeclocycline [<50] /

Pirlimycin Not detected 100 (100) Sancycline [<50] /

Neomycin 1000 1500 (1500) Amicycline [<50] /

NEO AMINOGLYCOSIDES Paramomycin [4000-20000] n.f.u. Meclocycline [<50] /

Apramycin 125 n.f.u. Methacycline [<50] /

Danofloxacin 14 30 Tylosin A 30 50 (100)

Enrofloxacin 14 Desmycosin 30 50 100** QUINO QUINOLONES Ciprofloxacin 16 TYLO MACROLIDES Tilmicosin Not detected 50

Marbofloxacin 14 75 Tulathromycin equivalents Not detected n.f.u.

Ofloxacin [<20] / Tildipirosine Not detected n.f.u.

EXTENSO LODs can be adapted to local regulations upon request | RUSSIA: Decision of the Board of the Eurasian Economic Commission dated February 13, 2018 N 28 | CHINA: Annex No. 235 of the Ministry of Agriculture and Rural Affairs of the People’s Republic of China - Maximum Residue Limits of Veterinary Drugs in Animal Foods | USA: Tolerance And/Or Target Testing Levels Of Animal Drug Residues In Milk (M-I-18-9 February 12, 2018) | tbd : to be determined / n.f.u : not for use in product for human consumption - not permissible taking into consideration the limit of the reference method / * : sum of the single compound and its epimer form / ** : sum of the single compound and its metabolites / *** : sum of all compounds of the family