COM1\ION SKIN PR()Btems
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CLAPA Adults Conference
Adults Cleft Conference Camden Lock, London, England Saturday 17 November 2018 The Cleft Lip and Palate Association (CLAPA) is the only national charity supporting people and families affected by cleft lip and/or palate in the UK from diagnosis through to adulthood. Timetable • • • • • • • • • • • • • • • • What’s today all about? • • • • Some ground rules and caveats • • • • • About the Adult Services Project • There are an estimated 75,000 people over the age of 16 living in the United Kingdom who were born with a cleft. • Understanding and supporting the unique needs and experiences of adults affected by cleft is very important to CLAPA. • From March 2018-February 2021, CLAPA is undertaking an exciting project looking at improving services for adults who were born with a cleft funded by the VTCT Foundation. • The goals are to research and understand the experiences, challenges and unmet needs of adults in the UK who were born with a cleft lip and/or palate. • The Adult Services Coordinator is the primary contact for this piece of work. What we did in Year One • • • • • So…what did we find at the roadshow? • We were humbled by how candidly people shared some of their most pivotal moments with us. • As you would expect, there were many different (oftentimes unique) experiences in the community, however there were some common themes that came up many times – these included: • The struggle of obtaining a successful referral to the cleft team as an adult • Being unsure what to expect at cleft team appointments • Not knowing (and health -
Oral Lichen Planus: a Case Report and Review of Literature
Journal of the American Osteopathic College of Dermatology Volume 10, Number 1 SPONSORS: ',/"!,0!4(/,/'9,!"/2!4/29s-%$)#)3 March 2008 34)%&%,,!"/2!4/2)%3s#/,,!'%.%8 www.aocd.org Journal of the American Osteopathic College of Dermatology 2007-2008 Officers President: Jay Gottlieb, DO President Elect: Donald Tillman, DO Journal of the First Vice President: Marc Epstein, DO Second Vice President: Leslie Kramer, DO Third Vice President: Bradley Glick, DO American Secretary-Treasurer: Jere Mammino, DO (2007-2010) Immediate Past President: Bill Way, DO Trustees: James Towry, DO (2006-2008) Osteopathic Mark Kuriata, DO (2007-2010) Karen Neubauer, DO (2006-2008) College of David Grice, DO (2007-2010) Dermatology Sponsors: Global Pathology Laboratory Stiefel Laboratories Editors +BZ4(PUUMJFC %0 '0$00 Medicis 4UBOMFZ&4LPQJU %0 '"0$% CollaGenex +BNFT2%FM3PTTP %0 '"0$% Editorial Review Board 3POBME.JMMFS %0 JAOCD &VHFOF$POUF %0 Founding Sponsor &WBOHFMPT1PVMPT .% A0$%t&*MMJOPJTt,JSLTWJMMF .0 4UFQIFO1VSDFMM %0 t'"9 %BSSFM3JHFM .% wwwBPDEPSg 3PCFSU4DIXBS[F %0 COPYRIGHT AND PERMISSION: written permission must "OESFX)BOMZ .% be obtained from the Journal of the American Osteopathic College of Dermatology for copying or reprinting text of .JDIBFM4DPUU %0 more than half page, tables or figurFT Permissions are $JOEZ)PGGNBO %0 normally granted contingent upon similar permission from $IBSMFT)VHIFT %0 the author(s), inclusion of acknowledgement of the original source, and a payment of per page, table or figure of #JMM8BZ %0 reproduced matFSJBMPermission fees -
Seborrheic Dermatitis: an Overview ROBERT A
Seborrheic Dermatitis: An Overview ROBERT A. SCHWARTZ, M.D., M.P.H., CHRISTOPHER A. JANUSZ, M.D., and CAMILA K. JANNIGER, M.D. University of Medicine and Dentistry at New Jersey-New Jersey Medical School, Newark, New Jersey Seborrheic dermatitis affects the scalp, central face, and anterior chest. In adolescents and adults, it often presents as scalp scaling (dandruff). Seborrheic dermatitis also may cause mild to marked erythema of the nasolabial fold, often with scaling. Stress can cause flare-ups. The scales are greasy, not dry, as commonly thought. An uncommon generalized form in infants may be linked to immunodeficiencies. Topical therapy primarily consists of antifungal agents and low-potency steroids. New topical calcineurin inhibitors (immunomodulators) sometimes are administered. (Am Fam Physician 2006;74:125-30. Copyright © 2006 American Academy of Family Physicians.) eborrheic dermatitis can affect patients levels, fungal infections, nutritional deficits, from infancy to old age.1-3 The con- neurogenic factors) are associated with the dition most commonly occurs in condition. The possible hormonal link may infants within the first three months explain why the condition appears in infancy, S of life and in adults at 30 to 60 years of age. In disappears spontaneously, then reappears adolescents and adults, it usually presents as more prominently after puberty. A more scalp scaling (dandruff) or as mild to marked causal link seems to exist between seborrheic erythema of the nasolabial fold during times dermatitis and the proliferation of Malassezia of stress or sleep deprivation. The latter type species (e.g., Malassezia furfur, Malassezia tends to affect men more often than women ovalis) found in normal dimorphic human and often is precipitated by emotional stress. -
FIG. 4A © O O Wo 2015/042110 Al III III II II III III 1 1 II III II II III III II III
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date W O 2015/042110 A l 2 6 March 2015 (26.03.2015) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61P 37/00 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, PCT/US20 14/056021 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, ΓΝ , IR, IS, JP, KE, KG, KN, KP, KR, 17 September 2014 (17.09.2014) KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, (25) Filing Language: English PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (26) Publication Language: English SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 61/880,522 20 September 2013 (20.09.2013) (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant: CHILDREN'S MEDICAL CENTER COR¬ GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, PORATION [US/US]; 55 Shattuck Street, Boston, Mas¬ TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, sachusetts 021 15 (US). -
Genital Lichen Simplex Chronicus (Eczema, Neurodermatitis, Dermatitis) !
Libby Edwards, MD Genital Lichen Simplex Chronicus (eczema, neurodermatitis, dermatitis) ! Lichen simplex chronicus (LSC), or eczema, is a common skin condition that is very itchy. Although not dangerous in any way, both the itching, and the pain from rubbing and scratching, can be miserable. Eczema/LSC of the genital area most often affects the scrotum of men, the vulva of women, or the rectal skin of both. Many people with eczema/LSC have had sensitive skin or eczema/LSC on other areas of the skin at some point, and many have a tendency towards allergies, especially hay fever or asthma. ! The skin usually appears red or dark, and thick from rubbing and scratching, sometimes with sores from scratching. ! The cause of eczema/LSC is not entirely clear. However, eczema/LSC starts with irritation that triggers itching. Often, at the office visit with the health care provider, the original infection or other initial cause of irritation is no longer present. Common triggers include a yeast or fungus infection, an irritating medication, moisturizer or lubricant, a wet bathing suit, anxiety or depression, over-washing, panty liners, sweat, heat, urine, a contraceptive jelly, an irritating condom, or any other activity or substance that can irritate the skin and start the itching. ! Although rubbing and scratching often feel good at first, rubbing irritates the skin and ultimately makes itching even worse, so that there is more scratching, then more itching, then more scratching. This is called the “itch-scratch cycle.” Treatment is very effective and requires clearing any infection and avoiding irritants as well as using a strong cortisone. -
4Th Annual Texas Children's Hospital Advanced Practice Provider
A Potpourri of Pediatric Dermatology 4th Annual Texas Children’s Hospital Advanced Practice Provider Conference April 2017 MOISE L. LEVY, M.D. DELL CHILDREN’S MEDICAL CENTER DELL MEDICAL SCHOOL/UT, AUSTIN AUSTIN, TX Conflicts of Interest Ø Anacor Ø Scioderm Ø Castle Creek Pharmaceuticals Ø Up to Date None Should Apply For This Presentation One way we are viewed… It’s just a birthmark 9 month old with asymptomatic scalp lesion noted in NICU; increases in size with straining But maybe something else… Sinus Pericranii Ø Communication between intra- and extracranial venous drainage pathways Ø Most are midline and non.pulsatile Ø Connect pericranial veins with superior sagittal sinus Ø TX depends on flow pattern/direction -Dominant; main flow via SP -Accessory; small flow via SP Neuroradiology 2007;49:505 Neurology 2009;72:e66 Case History 5 y/o girl w celiac disease Seen for evaluation of perianal growth Present, by hx, x 2 yrs No prior tx Case History Was seen by pediatric surgery Excised Condyloma - HPV 6, 16 Management? ARS – Pediatric Anogenital Warts When seeing a 5 yo with anogenital warts A. HPV testing should be done B. All cases are due to abuse C. All cases should be treated with imiquimod D. History and physical examination are key for suspicion of abuse E. Call Dr Eichenfield; he’ll know what to do Pediatric Anogenital Warts Age of onset and abuse - 6.5 ± 3.8 yrs (5.3 yrs) - 37% 2-12 yrs; 70% > 8 yrs - 4 yrs 8 months (83% female) HPV testing felt not of use… high subclinical History and PE key - physical findings abuse rare Arch Dermatol 1990;126:1575 Pediatrics 2005;116:815 Arch Dis Child 2006;91:696 Pediatr Dermatol 2006;23:199 J Pediatr Adolesc Gynecol 2013;26:e121 Age of Onset and Abuse Pediatr Dermatol 2006;23:199 ARS – Pediatric Anogenital Warts When seeing a 5 yo with anogenital warts A. -
Scalp Eczema Factsheet the Scalp Is an Area of the Body That Can Be Affected by Several Types of Eczema
12 Scalp eczema factsheet The scalp is an area of the body that can be affected by several types of eczema. The scalp may be dry, itchy and scaly in a chronic phase and inflamed (red), weepy and painful in an acute (eczema flare) phase. Aside from eczema, there are a number of reasons why the scalp can become dry and itchy (e.g. psoriasis, fungal infection, ringworm, head lice etc.), so it is wise to get a firm diagnosis if there is uncertainty. Types of eczema • Hair clips and headgear – especially those containing that affect the scalp rubber or nickel. Seborrhoeic eczema (dermatitis) is one of the most See the NES booklet on Contact Dermatitis for more common types of eczema seen on the scalp and hairline. details. It can affect babies (cradle cap), children and adults. The Irritant contact dermatitis is a type of eczema that skin appears red and scaly and there is often dandruff as occurs when the skin’s surface is irritated by a substance well, which can vary in severity. There may also be a rash that causes the skin to become dry, red and itchy. on other parts of the face, such as around the eyebrows, For example, shampoos, mousses, hair gels, hair spray, eyelids and sides of the nose. Seborrhoeic eczema can perm solution and fragrance can all cause irritant contact become infected. See the NES factsheets on Adult dermatitis. See the NES booklet on Contact Dermatitis for Seborrhoeic Dermatitis and Infantile Seborrhoeic more details. Dermatitis and Cradle Cap for more details. -
Skin Diseases in Wrestling
Skin conditions in wrestling – how to prevent Krisztián Gáspár, MD, PhD Assistant professor University of Debrecen Faculty of Medicine Department of Dermatology Debrecen, Hungary Disclosure • Presenter: Krisztián Gáspár • I have the Relationships with commercial interests: – Advisory Board/Speakers Bureau: none – Funding (Grants/Honoraria): none – Research/Clinical Trials: Eli Lilly, Novartis, Pfizer, Janssen, Sanofi, Abbvie – Speaker/Consulting Fees: Eli Lilly, Novartis, Janssen, Sanofi, Abbvie • None to disclose regarding this presentation Objectives • Normal and impaired skin barrier • Atopic dermatitis – model for understanding barrier • Skin diseases in wrestling • Treatments • Prevention techniques in skin infections Skin barrier Danger model: ”The basic function of immune system is not to distinct between self and non-self, but to recognize danger” Polly Matzinger, PhD, Immunologist, NIH In order to avoid or prevent a loss on the mat you need a good defense – The same is true for skin (an active defense) Skin barrier functions Physicochemical barrier and immunological barrier – in close morphological and functional connection Physicochemical barrier Immunological barrier (SIS) Stratum corneum: corneocytes • Epidermis, dermis Stratum granulosum: keratinocytes • Keratinocytes, dendritic cells, T cells Cornified envelop , structural proteins • Defensins, cytokines, chemokines (filaggrin) Lipid layer, proteases, protease inhibitors, defensins Tight junctions, corneodesmosomes Physicochemical barrier Genetics Environmental factors -
Nevus Sebaceous
Nevus Sebaceous A nevus sebaceous (NEE vuhs sih BAY shus) is a type of birthmark that usually appears on the scalp. It may also appear on the face but this is less common. It is made of extra oil glands in the skin. It starts as a flat pink or orange plaque (slightly raised area). Hair does not grow in a nevus sebaceous. Typically, these are fairly small areas of skin. However, they can sometimes be larger and more noticeable. These birthmarks usually look the same until puberty. Hormonal changes cause them to become more raised. During adolescence (teen years) they can become very bumpy and wart-like. This can make them bothersome when brushing, combing or cutting the hair. A nevus sebaceous does not go away on its own. The cause is unknown. As a person gets older, typically after adolescence, abnormal changes to the area can sometimes occur. Your child’s doctor will monitor it over time. Diagnosis Your child’s doctor can usually diagnosis this kind of birthmark. If unsure, the doctor may take a small piece of the birthmark as a biopsy. The doctor will send it to a lab to be looked at under a microscope. This can confirm the diagnosis. Treatment Generally, it is very safe for your child’s doctor to simply watch a nevus sebaceous over time. This is especially true while your child is young (before puberty). A nevus sebaceous will not affect your child’s health, but you or your child may still want it to be taken off. If your child’s nevus sebaceous is large or becomes bothersome, it may be removed. -
Lichen Simplex Chronicus
LICHEN SIMPLEX CHRONICUS http://www.aocd.org Lichen simplex chronicus is a localized form of lichenified (thickened, inflamed) atopic dermatitis or eczema that occurs in well defined plaques. It is the result of ongoing, chronic rubbing and scratching of the skin in localized areas. It is generally seen in patients greater than 20 years of age and is more frequent in women. Emotional stress can play a part in the course of this skin disease. There is mainly one symptom: itching. The rubbing and scratching that occurs in response to the itch can become automatic and even unconscious making it very difficult to treat. It can be magnified by seeming innocuous stimuli such as putting on clothes, or clothes rubbing the skin which makes the skin warmer resulting in increased itch sensation. The lesions themselves are generally very well defined areas of thickened, erythematous, raised area of skin. Frequently they are linear, oval or round in shape. Sites of predilection include the back of the neck, ankles, lower legs, upper thighs, forearms and the genital areas. They can be single lesions or multiple. This can be a very difficult condition to treat much less resolve. It is of utmost importance that the scratching and rubbing of the skin must stop. Treatment is usually initiated with topical corticosteroids for larger areas and intralesional steroids might also be considered for small lesion(s). If the patient simply cannot keep from rubbing the area an occlusive dressing might be considered to keep the skin protected from probing fingers. Since this is not a histamine driven itch phenomena oral antihistamines are generally of little use in these cases. -
Skin Conditions and Related Need for Medical Care Among Persons 1=74 Years United States, 1971-1974
Data from the Series 11 NATIONAL HEALTH SURVEY Number 212 Skin Conditions and Related Need for Medical Care Among Persons 1=74 Years United States, 1971-1974 DHEW Publication No. (PHS) 79-1660 U.S, DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service Office of the Assistant Secretary for Health National Center for Health Statistics Hyattsville, Md. November 1978 NATIONAL CENTIER FOR HEALTH STATISTICS DOROTHY P. RICE, Director ROBERT A. ISRAEL, Deputy Director JACOB J. FELDAMN, Ph.D., Associate Director for Amdy.sis GAIL F. FISHER, Ph.D., Associate Director for the Cooperative Health Statistics System ELIJAH L. WHITE, Associate Director for Data Systems JAMES T. BAIRD, JR., Ph.D., Associate Director for International Statistics ROBERT C. HUBER, Associate Director for Managewzent MONROE G. SIRKEN, Ph.D., Associate Director for Mathematical Statistics PETER L. HURLEY, Associate Director for Operations JAMES M. ROBEY, Ph.D., Associate Director for Program Development PAUL E. LEAVERTON, Ph.D., Associate Director for Research ALICE HAYWOOD,, Information Officer DIVISION OF HEALTH EXAMINATION STATISTICS MICHAEL A. W. HATTWICK, M.D., Director JEAN ROEERTS, Chiej, Medical Statistics Branch ROBERT S. MURPHY, Chiej Survey Planning and Development Branch DIVISION OF OPERATIONS HENRY MILLER, ChieJ Health -Examination Field Operations Branch COOPERATION OF THE U.S. BUREAU OF THE CENSUS Under the legislation establishing the National Health Survey, the Public Health Service is authorized to use, insofar as possible, the sesw?icesor facilities of other Federal, State, or private agencies. In accordance with specifications established by the National Center for Health Statis- tics, the U.S. Bureau of the Census participated in the design and selection of the sample and carried out the household interview stage of :the data collection and certain parts of the statis- tical processing. -
Dyshidrotic Eczema
University of Calgary PRISM: University of Calgary's Digital Repository Cumming School of Medicine Cumming School of Medicine Research & Publications 2014-09-16 Dyshidrotic eczema Leung, Alexander K.C.; Barankin, Benjamin; Hon, Kam Lun Enliven Archive Leung AK, Barankin B, Hon KL (2014) Dyshidrotic Eczema. Enliven: Pediatr Neonatol Biol 1(1): 002. http://hdl.handle.net/1880/50267 journal article Downloaded from PRISM: https://prism.ucalgary.ca Research Article www.enlivenarchive.org Enliven: Pediatrics and Neonatal Biology Dyshidrotic Eczema Alexander K. C. Leung1*, Benjamin Barankin2, and Kam Lun Hon3 1Clinical Professor of Pediatrics, University of Calgary, Pediatric Consultant, Alberta Children’s Hospital 2Medical Director and Founder, Toronto Dermatology Centre 3Professor of Pediatrics, Chinese University of Hong Kong * Corresponding author: Alexander K. C. Leung, MBBS, FRCPC, FRCP Citation: Leung AK, Barankin B, Hon KL (2014) Dyshidrotic Eczema. (UK & Irel), FRCPCH, FAAP, Clinical Professor of Pediatrics, University Enliven: Pediatr Neonatol Biol 1(1): 002. of Calgary, Pediatric Consultant, Alberta Children’s Hospital, Canada, Tel: Copyright:@ 2014 Dr. Alexander K. C. Leung. This is an Open Access (403) 230-3322; Fax: (403) 230-3322; E-mail: [email protected] article published and distributed under the terms of the Creative Commons th Received Date: 14 August 2014 Attribution License, which permits unrestricted use, distribution and th Accepted Date: 10 September 2014 reproduction in any medium, provided the original author and source are th Published Date: 16 September 2014 credited. Abstract Dyshidrotic eczema, also known as dyshidrotic dermatitis or pompholyx, is characterized by pruritic, tense, deep-seated vesicles mainly on the palms and lateral surfaces of the fingers.