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Dispersal of a Neotropical Nutmeg (Virola Sebifera) by Birds
DISPERSAL OF A NEOTROPICAL NUTMEG (VIROLA SEBIFERA) BY BIRDS HENRY F. HOWE Program in Evolutionary Ecologyand Behavior, Department of Zoology, University of Iowa, Iowa City, Iowa 52242 USA Al•ST•CT.--Feeding assemblagesof birds were observedat a Panamanian population of Virola sebifera (Myristicaceae) in order to test the hypothesisthat plants producing especiallynutritious fruits in limited supply should be efficiently dispersedby a small set of obligate frugivores. Virola sebifera producesan encapsulatedarillate seedthat is swallowed by birds shortly after dehiscence. The aril (54% lipid, 7% protein, 8% usable carbohydrate) is retained; the seed is regurgitated intact within 10-30 min. The plant produces 1-96 (Yc= 24) ripe arillate seedseach day, of which 40-89% (Yc= 76%) are taken within a few hours of dawn. The visitor assemblageconsists of six resident frugivores. Three [Chestnut-mandibledToucan (Ramphastosswainsonii), Keel-billed Toucans (R. sulfuratus), and Masked Tityra (Tityra semifasciata)] are "regulars," likely to visit all trees; three [Slaty-tailed Trogon (2•rogonmassena), Rufous Motmot (Baryphthengus martii), and Collared Aracari (Pteroglossustorquatus) are common throughout the Barro Colorado Forest but do not consistently use Virola sebifera. The Chestnut-mandibled Toucan is responsiblefor 43% of the seedsremoved by birds, although it is also responsiblefor more seedwaste (regurgi- tation under the tree crown) than other visitors. Rapid depletion of available fruits each morning and active defense of the crowns by toucans suggest a limited and preferred food resource for "regulars"in the assemblage. A review of recent work indicatesthat the assemblagevisiting Virola sebiferais similar to that frequenting its larger congener (V. surinamensis) but is far smaller and more specialized than those visiting other fruiting trees in the same forest. -
An Update on Ethnomedicines, Phytochemicals, Pharmacology, and Toxicity of the Myristicaceae Species
Received: 30 October 2020 Revised: 6 March 2021 Accepted: 9 March 2021 DOI: 10.1002/ptr.7098 REVIEW Nutmegs and wild nutmegs: An update on ethnomedicines, phytochemicals, pharmacology, and toxicity of the Myristicaceae species Rubi Barman1,2 | Pranjit Kumar Bora1,2 | Jadumoni Saikia1 | Phirose Kemprai1,2 | Siddhartha Proteem Saikia1,2 | Saikat Haldar1,2 | Dipanwita Banik1,2 1Agrotechnology and Rural Development Division, CSIR-North East Institute of Prized medicinal spice true nutmeg is obtained from Myristica fragrans Houtt. Rest spe- Science & Technology, Jorhat, 785006, Assam, cies of the family Myristicaceae are known as wild nutmegs. Nutmegs and wild nutmegs India 2Academy of Scientific and Innovative are a rich reservoir of bioactive molecules and used in traditional medicines of Europe, Research (AcSIR), Ghaziabad, 201002, Uttar Asia, Africa, America against madness, convulsion, cancer, skin infection, malaria, diar- Pradesh, India rhea, rheumatism, asthma, cough, cold, as stimulant, tonics, and psychotomimetic Correspondence agents. Nutmegs are cultivated around the tropics for high-value commercial spice, Dipanwita Banik, Agrotechnology and Rural Development Division, CSIR-North East used in global cuisine. A thorough literature survey of peer-reviewed publications, sci- Institute of Science & Technology, Jorhat, entific online databases, authentic webpages, and regulatory guidelines found major 785006, Assam, India. Email: [email protected] and phytochemicals namely, terpenes, fatty acids, phenylpropanoids, alkanes, lignans, flavo- [email protected] noids, coumarins, and indole alkaloids. Scientific names, synonyms were verified with Funding information www.theplantlist.org. Pharmacological evaluation of extracts and isolated biomarkers Council of Scientific and Industrial Research, showed cholinesterase inhibitory, anxiolytic, neuroprotective, anti-inflammatory, immu- Ministry of Science & Technology, Govt. -
A Molecular Taxonomic Treatment of the Neotropical Genera
An Intrageneric and Intraspecific Study of Morphological and Genetic Variation in the Neotropical Compsoneura and Virola (Myristicaceae) by Royce Allan David Steeves A Thesis Presented to The University of Guelph In partial fulfillment of requirements for the degree of Doctor of Philosophy in Botany Guelph, Ontario, Canada © Royce Steeves, August, 2011 ABSTRACT AN INTRAGENERIC AND INTRASPECIFIC STUDY OF MORPHOLOGICAL AND GENETIC VARIATION IN THE NEOTROPICAL COMPSONEURA AND VIROLA (MYRISTICACEAE) Royce Allan David Steeves Advisor: University of Guelph, 2011 Dr. Steven G. Newmaster The Myristicaceae, or nutmeg family, consists of 21 genera and about 500 species of dioecious canopy to sub canopy trees that are distributed worldwide in tropical rainforests. The Myristicaceae are of considerable ecological and ethnobotanical significance as they are important food for many animals and are harvested by humans for timber, spices, dart/arrow poison, medicine, and a hallucinogenic snuff employed in medico-religious ceremonies. Despite the importance of the Myristicaceae throughout the wet tropics, our taxonomic knowledge of these trees is primarily based on the last revision of the five neotropical genera completed in 1937. The objective of this thesis was to perform a molecular and morphological study of the neotropical genera Compsoneura and Virola. To this end, I generated phylogenetic hypotheses, surveyed morphological and genetic diversity of focal species, and tested the ability of DNA barcodes to distinguish species of wild nutmegs. Morphological and molecular analyses of Compsoneura. indicate a deep divergence between two monophyletic clades corresponding to informal sections Hadrocarpa and Compsoneura. Although 23 loci were tested for DNA variability, only the trnH-psbA intergenic spacer contained enough variation to delimit 11 of 13 species sequenced. -
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanismss
Supplemental Material can be found at: /content/suppl/2020/12/18/73.1.202.DC1.html 1521-0081/73/1/202–277$35.00 https://doi.org/10.1124/pharmrev.120.000056 PHARMACOLOGICAL REVIEWS Pharmacol Rev 73:202–277, January 2021 Copyright © 2020 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license. ASSOCIATE EDITOR: MICHAEL NADER Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanismss Antonio Inserra, Danilo De Gregorio, and Gabriella Gobbi Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada Abstract ...................................................................................205 Significance Statement. ..................................................................205 I. Introduction . ..............................................................................205 A. Review Outline ........................................................................205 B. Psychiatric Disorders and the Need for Novel Pharmacotherapies .......................206 C. Psychedelic Compounds as Novel Therapeutics in Psychiatry: Overview and Comparison with Current Available Treatments . .....................................206 D. Classical or Serotonergic Psychedelics versus Nonclassical Psychedelics: Definition ......208 Downloaded from E. Dissociative Anesthetics................................................................209 F. Empathogens-Entactogens . ............................................................209 -
Plants from the Brazilian Traditional Medicine: Species from the Books Of
Revista Brasileira de Farmacognosia 27 (2017) 388–400 ww w.elsevier.com/locate/bjp Original Article Plants from the Brazilian Traditional Medicine: species from the books of the Polish physician Piotr Czerniewicz (Pedro Luiz Napoleão Chernoviz, 1812–1881) a,c d b,c b,c,∗ Letícia M. Ricardo , Juliana de Paula-Souza , Aretha Andrade , Maria G.L. Brandão a Ministério da Saúde, Departamento de Assistência Farmacêutica e Insumos Estratégicos, Esplanada dos Ministérios, Brasília, DF, Brazil b Centro Especializado em Plantas Aromáticas, Medicinais e Tóxicas, Museu de História Natural e Jardim Botânico, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil c Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil d Universidade Federal de São João del Rei, Campus Sete Lagoas, Sete Lagoas, MG, Brazil a b s t r a c t a r t i c l e i n f o Article history: The Brazilian flora is very rich in medicinal plants, and much information about the traditional use of Received 1 October 2016 the Brazilian plants is only available from early literature and we are facing a rapid process of loss of Accepted 10 January 2017 biodiversity. To retrieve data about useful plants registered in the books of the Polish physicist P.L.N. Available online 2 March 2017 Chernoviz, who lived in Brazil for 15 years in the 19th century. The aim is to improve our knowledge about Brazilian plants, and to ensure the benefits of sharing it with potential users. Data about Brazilian Keywords: plants were obtained from six editions of the book Formulary and Medical Guide (Formulário e Guia Historical records Médico), published in 1864, 1874, 1888, 1892, 1897 and 1920. -
Myristicaceae
1762 TROPICAL FORESTS / Myristicaceae Burtt Davy J (1938) Classification of Tropical Woody importance. Fruit of the Myristicaceae, particularly Vegetation Types. Oxford, UK: Imperial Forestry In- the lipid-rich aril surrounding the seed in some stitute. species, are important as food for birds and mam- Champion HG and Seth SK (1968) Revised Survey of the mals of tropical forests. Numerous species are valued Forest Types of India. New Delhi, India: Manager of by humans as sources of food, medicine, narcotics, Publications, Government of India. and timber, including Myristica fragrans, the source Collins NM, Sagyer JA, and Whitmore TC (eds) (1991) of nutmeg and mace, the spices of commerce. The Conservation Atlas of Tropical Forests: Asia and Pacific. London: Macmillan. Throughout the geographical range of Myristica- Edward MV (1950) Burma Forest Types. Indian Forest ceae, aromatic leaves, often stellate pubescence, a Records (new series). Silviculture 7(2). Dehra Dun, India: unique arborescent architecture (Figure 1), and sap Forest Research Institute. the color of blood (Figure 2) are characteristics that Holmer CH (1958) The broad pattern of climate and strongly enhance recognition of this family in the vegetation distribution in Ceylon. In Proceedings of a field. Species of this family are usually dioecious. Symposium on Humid Tropics Vegetation, Kanly. Paris: Flowers are tiny and found in paniculate inflores- UNESCO. cences, with filaments of stamens fused into a IUCN (1988) The Red Data Book. Switzerland: IUCN. column, giving rise to either free or fused anthers Kurz S (1877) Forest Flora of British Burma, 2 vols. (Figures 3 and 4). Fruits are one-seeded, dehiscent or Calcutta, India: Bishen Singh, Dehra Dun. -
Biologia Reprodutiva E Fenologia De Virola Sebifera Aubl. (Myristicaceae) Em Mata Mesofítica De Uberlândia, MG, Brasil EDDIE LENZA1,3 E PAULO EUGÊNIO OLIVEIRA2
Revista Brasil. Bot., V.29, n.3, p.443-451, jul.-set. 2006 Biologia reprodutiva e fenologia de Virola sebifera Aubl. (Myristicaceae) em mata mesofítica de Uberlândia, MG, Brasil EDDIE LENZA1,3 e PAULO EUGÊNIO OLIVEIRA2 (recebido: 3 de novembro de 2005; aceito: 27 de julho de 2006) ABSTRACT – (Reproductive biology and phenology of Virola sebifera Aubl. (Myristicaceae) in a mesophytic forest of Uberlândia, MG, Brazil). We studied some aspects of the floral and reproductive biology of Virola sebifera Aubl., a dioecious woody species of mesophytic forest in Uberlândia, Minas Gerais. The sex of 54 individuals in the study area was determined in three consecutive reproductive periods. Reproductive phenology of 11 individuals of each sex was followed from October 1998 to April 2000. The sex ratio was always male biased and no sex change was observed, which indicates sexual stability. The flowering was annual, relatively long and massive (cornucopia type) with male individuals blooming earlier and for a longer period than the female ones. Flowers, grouped in paniculate inflorescences, were small (3 and 4 mm long for male and female flowers respectively) and inconspicuous, with an infundibuliforme periant and inserted reproductive whorls. Both male and female flowers have long lifespan (ca. one week). Pollen in male flowers is the sole floral reward. Strong scent and similar flower morphology between sexes may lead to visits to rewardless female flowers (floral self-mimicry). Natural pollination resulted in relatively low number of initiated fruits (5.8%). Fruit-set from bagged unpollinated flowers (apomixis) were much lower than from natural pollination. These results show that V. -
Dextromethorphan and Memantine After Ketamine Analgesia: a Randomized Control Trial
Drug Design, Development and Therapy Dovepress open access to scientific and medical research Open Access Full Text Article ORIGINAL RESEARCH Dextromethorphan and memantine after ketamine analgesia: a randomized control trial This article was published in the following Dove Press journal: Drug Design, Development and Therapy Elodie Martin,1 Marc Sorel,2 Purpose: Intravenous ketamine is often prescribed in severe neuropathic pain. Oral N- 3 Véronique Morel, Fabienne methyl-D-aspartate receptor (NMDAR) antagonists might prolong pain relief, reducing the 4 4 Marcaillou, Pascale Picard, frequency of ketamine infusions and hospital admissions. This clinical trial aimed at asses- Noémie Delage,4 Florence sing whether oral dextromethorphan or memantine might prolong pain relief after intrave- Tiberghien,5 Marie-Christine 6 6 nous ketamine. Crosmary, Mitra Najjar, Renato Colamarino,6 Christelle Créach,7,8 Patients and methods: A multicenter randomized controlled clinical trial included 60 Béatrice Lietar,7 Géraldine Brumauld patients after ketamine infusion for refractory neuropathic pain. Dextromethorphan (90 mg/ de Montgazon,9 Anne Margot- day), memantine (20 mg/day) or placebo was given for 12 weeks (n=20 each) after ketamine 10 11,12 Duclot, Marie-Anne Loriot, infusion. The primary endpoint was pain intensity at one month. Secondary endpoints 11,12 13 Céline Narjoz, Céline Lambert, included pain, sleep, anxiety, depression, cognitive function and quality of life evaluations 13 1,3 Bruno Pereira, Gisèle Pickering up to 12 weeks. 1Université Clermont Auvergne, Pharmacologie Results: At 1 month, dextromethorphan maintained ketamine pain relief (Numeric Pain Fondamentale Et Clinique de la Douleur, Neuro- Dol, Inserm 1107, F-63000 Clermont-Ferrand, Scale: 4.01±1.87 to 4.05±2.61, p=0.53) and diminished pain paroxysms (p=0.03) while pain France; 2Centre D’evaluation et de Traitement de intensity increased significantly with memantine and placebo (p=0.04). -
From Panama, with a Key to Panamanian Species
ZooKeys 1047: 1–25 (2021) A peer-reviewed open-access journal doi: 10.3897/zookeys.1047.68409 RESEARCH ARTICLE https://zookeys.pensoft.net Launched to accelerate biodiversity research Four new species of Aspidiotini (Hemiptera, Diaspididae, Aspidiotinae) from Panama, with a key to Panamanian species Jiufeng Wei1, Scott A. Schneider2, Roxanna D. Normark3, Benjamin B. Normark3,4 1 College of Plant Protection, Shanxi Agricultural University, Taigu, Shanxi, 030801, China 2 USDA, Ag- ricultural Research Service, Henry A. Wallace Beltsville Agricultural Research Center, Systematic Entomology Laboratory, Building 005 – Room 004, 10300 Baltimore Avenue, Beltsville, MD, 20705, USA 3 Department of Biology, University of Massachusetts, Amherst, MA 01003, USA 4 Graduate Program in Organismic and Evolutionary Biology, University of Massachusetts, Amherst, MA 01003, USA Corresponding author: Scott A. Schneider ([email protected]) Academic editor: Roger Blackman | Received 7 May 2021 | Accepted 4 June 2021 | Published 24 June 2021 http://zoobank.org/77E36ADC-70CF-494F-A346-89B29D09CAFE Citation: Wei J, Schneider SA, Normark RD, Normark BB (2021) Four new species of Aspidiotini (Hemiptera, Diaspididae, Aspidiotinae) from Panama, with a key to Panamanian species. ZooKeys 1047: 1–25. https://doi. org/10.3897/zookeys.1047.68409 Abstract Four new species of armored scale insect, Clavaspis selvatica sp. nov., Clavaspis virolae sp. nov., Davidsonaspis tovomitae sp. nov., and Rungaspis neotropicalis sp. nov., are described and illustrated from Panama. We also transfer two previously described species of Panamanian Aspidiotini to new genera, Hemiberlesia crescentiae (Ferris) comb. nov. and Rungaspis rigida (Ferris) comb. nov., and report the first record ofSelenaspidopsis browni Nakahara in Panama. A key to the species of Aspidiotini occurring in Panama is provided. -
First Records of Stranded Nutnegs Myristica Fragrans Houttuyn, 1774 (Magnoliales: Myristicaceae) on the Irish Coast and a Review of North Atlantic Records
Bulletin of the Irish Biogeographical Society Number 44 (2020) FIRST RECORDS OF STRANDED NUTNEGS MYRISTICA FRAGRANS HOUTTUYN, 1774 (MAGNOLIALES: MYRISTICACEAE) ON THE IRISH COAST AND A REVIEW OF NORTH ATLANTIC RECORDS *Declan T. G. Quigley1, Liam MacNamara2 and Paul A. Gainey3 1Sea Fisheries Protection Authority, Eastern Region, West Pier, Howth, Co. Dublin, Ireland. 2Derreen, Craggagh, Fanore, Co. Clare, Ireland. 3Polwithen Road, Penryn, Cornwall TR10 8QT, U.K. *Corresponding author e-mail: <[email protected]> Abstract Between July and October 2019, LMN discovered a total of 23 nutmegs Myristica fragrans Houttuyn, 1774 stranded at various locations along the shoreline of County Clare, on the Atlantic coast of western Ireland. The specimens represent the first records of stranded M. fragrans seeds from Irish waters. The occurrence and potential provenance of stranded nutmegs on Irish and North Atlantic maritime shores are reviewed. Flotation experiments suggest that some stranded nutmegs may represent true peregrine trans-Atlantic drifters while others may have been locally discarded. Key words: Nutmeg, Myristica fragrans, stranded nutmegs, Irish waters and North Atlantic. Introduction The pantropical family Myristicaceae consists of c.21 genera and c.520 species of woody trees, shrubs and, occasionally lianas (Cristenhusz and Byng, 2016; Santamari-Aguilar et al., 2019). Myristica is a genus of trees native to tropical Asia and the Western Pacific. Although at least 446 species and sub-species of Myristica have been described (Anon., 2020a), the identification of Myristica species based on traditional morphological criteria has always proven difficult, and so far, even DNA barcoding techniques based on rbcL and matK genes have generally failed to satisfactorily differentiate between species (Tallei and Kolondam, 2015; Nanlohy et al., 2017; Swetha et al., 2019). -
ICE 2020/1 Seized Materials Test Group
INTERNATIONAL COLLABORATIVE EXERCISES (ICE) Summary Report ICE Round 2020/1 1 SEIZED MATERIALS / 20 ICE 20 International Collaborative Exercises (ICE) Summary report 2020/1-Seized Materials Final summary report for ICE 2020/1 Seized Materials Test Group Original language: English © United Nations, January 2021. All rights reserved, worldwide. The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. This publication has not been formally edited. ICE 2020/1-SM Copyright © 2021 UNODC Page 1 of 104 International Collaborative Exercises (ICE) Summary report 2020/1-Seized Materials Acknowledgements The Laboratory and Scientific Section (LSS) of the UNODC, headed by Dr. Justice Tettey, wishes to express its appreciation and thanks to all laboratories for participating in the International Collaborative Exercises (ICE) round 2020/1. The valuable comments and contribution from the following members of the International Panel of Forensic Experts are gratefully acknowledged: Mr. Benoit Archambault, Health Canada, Canada Mr. Elvio Dias Botelho, Brazilian Federal Police, Brazil Prof. Heesun Chung, Sungkyunkwan University, Republic of Korea Prof. Niamh Nic Daéid, University of Dundee, Scotland, UK Mr. Scott Oulton, Drug Enforcement Administration, USA Ms. Catherine Quinn, Victoria Police, Australia Prof. Franco Tagliaro, University of Verona, Italy Dr. Angeline Tiong Whei Yap, Health Sciences Authority, Singapore In addition, LSS would like to acknowledge the valuable contribution of the Chemical Metrology Laboratory of the Health Sciences Authority, Singapore, for the provision of specific software used for the quantitative statistical calculations in the ICE programme. -
Separation, Quantification and Control of Enatiomers of the Key Starting Material of Dextromethorphan Hydrobromide
Journal of Applied Pharmaceutical Science Vol. 8(08), pp 032-038, August, 2018 Available online at http://www.japsonline.com DOI: 10.7324/JAPS.2018.8805 ISSN 2231-3354 Separation, Quantification and Control of Enatiomers of the Key Starting Material of Dextromethorphan Hydrobromide Ajit Anerao*, Vishal Solase, Amol More, Nitin Pradhan R&D Centre (API), Wanbury Ltd., EL-16, TTC Industrial Estate, Mahape, Navi Mumbai 400710, India. ARTICLE INFO ABSTRACT Article history: Objective: Enantiomeric resolution of racemic 1-(4-Methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, a key Received on: 16/05/2018 starting material in the synthesis of the antitussive agent dextromethorphan hydrobromide. Material and method: Accepted on: 11/07/2018 Chiral liquid chromatographic method is developed and enantiomers are resolved on a Chiralpak ID-3 column using Available online: 31/08/2018 gradient mode of elution. Mobile phase A and B containing a mixture of 0.1% diethylamine in acetonitrile and 0.1% diethylamine in methanol respectively are optimized with the timed programme. The flow rate is 1.0 mL/minute and the column temperature was maintained at 40°C. Ultraviolet detection was performed at 280 nm wavelength and Key words: the injection volume was 20 μL. Results: The resolution between the enantiomers is found to be more than 2.5. The HPLC; chiral purity; developed method is extensively validated and proved to be robust. The limit of detection and limit of quantification dextromethorphan; of unwanted (R)-enantiomer is found to be 0.0075% and 0.025% with respect to test concentration, respectively. The development; validation.