Intake of Omega-3 Long Chain Polyunsaturated Fatty Acid (N-3 LCPUFA)
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University of Wollongong Research Online University of Wollongong Thesis Collection University of Wollongong Thesis Collections 2013 Intake of omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) among Australian children (2-16 years): in depth nutrient and food analysis Setyaningrum Rahmawaty University of Wollongong Recommended Citation Rahmawaty, Setyaningrum, Intake of omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) among Australian children (2-16 years): in depth nutrient and food analysis, Doctor of Philosophy thesis, School of Health Sciences, University of Wollongong, 2013. http://ro.uow.edu.au/theses/3945 Research Online is the open access institutional repository for the University of Wollongong. For further information contact the UOW Library: [email protected] INTAKE OF OMEGA-3 LONG CHAIN POLYUNSATURATED FATTY ACID (n-3 LCPUFA) AMONG AUSTRALIAN CHILDREN (2-16 YEARS): In depth nutrient and food analysis A thesis submitted in fulfilment of the requirements for the award of the degree DOCTOR OF PHILOSOPHY from UNIVERSITY OF WOLLONGONG by Setyaningrum Rahmawaty Grad Dip. III Nutr (Academy of Nutrition Semarang, Indonesia) Grad Dip. IV Clin Nutr (Brawijaya University, Indonesia) MHSc. Clin Nutr (Gadjah Mada University, Indonesia) SCHOOL OF HEALTH SCIENCES 2013 Certification I, Setyaningrum Rahmawaty, declare that this thesis, submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy, in the School of Health Sciences, University of Wollongong, is wholly my own work unless otherwise referenced or acknowledged. The document has not been submitted for qualifications at any other academic institution. Setyaningrum Rahmawaty 1 July 2013 ii “Innallooha laa yughoyyiruma biqoumin hatta yughoyyiruma bi anfusihim – verily, He will not change the good condition of a people as long as they do not change their state of goodness themselves” Qur’an Surah Ar-Ra’d 11 iii Dedicated to: My country, Indonesia The memory of my Father, Mother and elder Brother iv Funding sources This study was supported by a scholarship from Directorate General of Higher Education Indonesia (DIKTI) for lecturer in universities in Indonesia and University of Muhammadiyah Surakarta Indonesia. Small grant scheme was also provided by Metabolic Research Centre and Higher Degree Research Student Funding at the School of Health Sciences, University of Wollongong. v Acknowledgments I would like to offer my sincere gratitude to Almighty Allah first for enabling me to undertake and successfully complete the hardest journey of my life in the form of this thesis. If there are some moments in life when one fails to express their feelings, perhaps this is that point in my life at least. I can hardly think of proper words that can convey what I feel deep in my heart; I can only recall many ups and downs during this three a half years long venture, with friendly faces of many people around joining their hands to help me. It is not possible to list all the names and narrate how they supported me; since both time and space will fall short for this. I am grateful to all those people whose support, contribution and well wishes proved invaluable along the way. However, I feel indebted to: - Prof. Bambang Setiadji and staffs at the University of Muhammadiyah Surakarta. Thank you very much for supporting me from the beginning to get funding from the DIKTI until finishing my PhD. - A/Prof. Barbara Meyer, thanks for being such an ‘enthusiastic and very thorough’ supervisor as well as being mom, friend and colleague; A/Prof. Karen Charlton, thanks for being a ‘smart and nice’ supervisor and; A/Prof. Philippa Lyons-Wall, thanks for being a ‘lovely’ supervisor; Dr Marijka Batterham, thanks for her ‘nice’ statistical consultant. I really enjoy learning through your different styles of guiding and supervising me to be a better scientist. - All participants in the Fish Survey and Kids’ Omega-3 Intake Study as well as a number of media persons, child care centres, mother groups, supermarkets, public offices and private primary schools in Wollongong: Sam and Adam from Mercury, thanks for the great shoot and news; Scoot from Win television; Emily from ABC Illawarra; Miss Nicole Delbridge from Illawarra Christian school and Jenny Werakso from St Brigid’s Catholic school. - Prof Paul Else, Dr. Todd Mitchell and Dr Simon Brown, thanks for sharing your knowledge about how to do cheek cell sampling and fatty acid extraction. vi - Dr Jimmy Louie, thank you for his assistance in dietary analysis programming. - To Adam, Beryl, Lucy, Nola, Gai-Ellen, Sandie, Jenny and Anne, thanks a lot for your great service during my PhD at the School of Health Sciences. - Zoe, Samuel Eather, Hanieh, Sarah Norris and David, thanks so much for your kind support in data collection and working in lab (they never said ‘no/wait’ – so nice) ; Andi, Lukman, Yusuf, Dhany and Caesar many thanks for sharing your knowledge and valuable information about computer/mathematic programming. - Bothaina Bukatow, my best friend indeed!!!...I will miss walking & ‘fighting’ when exploring Wollongong and discussing our PhD progress; Josip Matesic, thanks for sharing Australia…I felt confidence to do my research here; my officemates (Dian, Li Min, Katherine, Jo, Ali, Jamila, Alisa, Khlood, Bel) - nice gossip, study, etc…wish all the best for you all friends!!! - A big thanks to my sisters, brothers, nieces, nephews for all their supports and prayers for me. Last but not least, to my beloved late parents; my father, M Busro Busraini Burhani and my mother, Nangimah who cannot see me with this achievement. There is not even a single word that can express my deep feeling for everything they have given me in my life. May Allah shower His blessings on them and gave them a pleasant abode in ‘Jannat ul Firdous’ - Aameen. And many thanks to Najeeb’i’, your support from a thousand miles made the final stage of my PhD journey colorful. vii Table of contents Page Certification ...................................................................................................................... ii Funding sources ................................................................................................................. v Acknowledgements ......................................................................................................... vi Table of contents ........................................................................................................... viii Tables ................................................................................................................................ x Figures ............................................................................................................................ xii Abbreviations ................................................................................................................ xiii Publications ..................................................................................................................... xv Abstract ......................................................................................................................... xvii Chapter 1 - Introduction .................................................................................................... 1 1.1 An overview of n-3 LCPUFA .................................................................................. 2 1.1.1 Dietary source of n-3 LCPUFA ................................................................... 2 1.1.2 Metabolism of n-3 LCPUFA ........................................................................ 3 1.1.3 Eicosanoids metabolism.... ........................................................................... 4 1.2 Health benefits of n-3 LCPUFA in children ............................................................ 6 1.2.1 The role of n-3 LCPUFA on brain development and school children’s performance ................................................................................................. 6 1.2.2 The role of n-3 LCPUFA in chronic-diseases prevention.... ........................ 9 1.3 Dietary n-3 LCPUFA intake and fish consumption in children’s diet ................... 12 1.3.1 International perspective on n-3 LCPUFA intake in children .................... 12 1.3.2 Dietary n-3 LCPUFA intake in Australian children.... ............................... 14 1.3.2.1 Dietary recommendations for n-3 LCPUFA intake for Australian children.... ..................................................................................... 14 1.3.2.2 Situational analysis: dietary n-3 LCPUFA intake in Australian children ......................................................................................... 16 1.4 Factors that influence fish/or seafood consumption............................................... 17 1.5 Foods enriched with n-3 LCPUFA – an alternative source of n-3 LCPUFA intake and their potential health benefits .......................................................................... 18 1.6 Methods to improve dietary intake in children ...................................................... 25 1.6.1 Intervention Mapping – a stepwise approach for designing behaviour changes development ................................................................................. 24 1.6.2 Parent’s influence to children’ eating habit ................................................ 26 1.6.3 Dietary modelling as a strategy to meet dietary recommendation.... ......... 26 1.6.4 Food pattern analysis .................................................................................