2013 BGA Marseille
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Fatty-Acid Binding Proteins Modulate Sleep and Enhance Long-Term Memory Consolidation in Drosophila Jason R
Washington University School of Medicine Digital Commons@Becker Open Access Publications 2011 Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila Jason R. Gerstner University of Wisconsin - Madison William M. Vanderheyden Washington University School of Medicine in St. Louis Paul J. Shaw Washington University School of Medicine in St. Louis Charles F. Landry Scarab Genomics Jerry C. P. Yin University of Wisconsin - Madison Follow this and additional works at: https://digitalcommons.wustl.edu/open_access_pubs Part of the Medicine and Health Sciences Commons Recommended Citation Gerstner, Jason R.; Vanderheyden, William M.; Shaw, Paul J.; Landry, Charles F.; and Yin, Jerry C. P., ,"Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila." PLoS One.,. e15890. (2011). https://digitalcommons.wustl.edu/open_access_pubs/510 This Open Access Publication is brought to you for free and open access by Digital Commons@Becker. It has been accepted for inclusion in Open Access Publications by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Fatty-Acid Binding Proteins Modulate Sleep and Enhance Long-Term Memory Consolidation in Drosophila Jason R. Gerstner1*¤, William M. Vanderheyden2, Paul J. Shaw2, Charles F. Landry3, Jerry C. P. Yin1,4,5* 1 Department of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, 2 Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, 3 Scarab Genomics, LLC, Madison, Wisconsin, United States of America, 4 Department of Neurology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, 5 Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America Abstract Sleep is thought to be important for memory consolidation, since sleep deprivation has been shown to interfere with memory processing. -
2018 Ibangs Meeting: the 20Th Annual Genes, Brain & Behavior Meeting
5/25/2018 Program for Thursday, May 17th 2018 IBANGS MEETING: THE 20TH ANNUAL GENES, BRAIN & BEHAVIOR MEETING WELCOME PROGRAM INDEXES PROGRAM FOR THURSDAY, MAY 17TH Days: next day all days View: session overview talk overview 08:30-16:00 Session FV: Pre-IBANGS Satellite Meeting, Functional Validation for Neurogenetics Location: Phillips Hall in the Siebens building room 1-11. The Siebens building is located at the Downtown Mayo Clinic Campus (not the Mayo Civic Center). Description:The transformative nature of next generation sequencing has changed how neuroscientists approach genomic sequence variation. Highly multiplexed molecular testing is providing an expanded level of information from which to make informed phenotypic predictions. The importance of this is reflected in the unprecedented expansion of genomic testing to determine the basis of neurologic conditions. Genomic testing results in many instances provide a definitive basis of a neurologic condition. However, in almost a high proportion of cases, the genomic sequencing results are confounded by the ambiguity of variants with uncertain clinical significance. Herein lies the key with which institutions will lead in the area of genomic medicine. There exists a critical need to provide a mechanism by which uncertain findings can be functionally characterized and translated into clinically actionable results. It is within thisr ealm that academic societies such as IBANGS can have a substantial and informative role on the future of clinical research and practice. This symposium will introduce the challenges and opportunities that exist in the field of human clinical neurogenetics and follow this with presentations of active work in the field of functional genetic finding validation for neurogenetics with a look to the future of genomic neurogenetics. -
Regulation of Learning by Epha Receptors: a Protein Targeting Study
The Journal of Neuroscience, November 1, 1999, 19(21):9538–9549 Regulation of Learning by EphA Receptors: a Protein Targeting Study R. Gerlai,1 N. Shinsky,1 A. Shih,1 P. Williams,2 J. Winer,2 M. Armanini,1 B. Cairns,3 J. Winslow,1 W.-Q. Gao,1 and H. S. Phillips1 Genentech, Inc., Departments of 1Neuroscience, 2Research BioAssay, and 3Pathology, South San Francisco, California 94080 EphA family receptor tyrosine kinases and their ephrin-A li- spontaneous alternation and context-dependent fear condi- gands are involved in patterning axonal connections during tioning, sensitive to hippocampal function, whereas activation brain development, but until now a role for these molecules in of EphA by infusion of an agonist immunoadhesin results in the mature brain had not been elucidated. Here, we show that enhanced performance on these tasks. Because the two be- both the EphA5 receptor and its ephrin-A ligands (2 and 5) are havioral tasks have different motivational, perceptual, and mo- expressed in the adult mouse hippocampus, and the EphA5 tor requirements, we infer the changes were not caused by protein is present in a phosphorylated form. Because there are these performance factors but rather to cognitive alterations. no pharmacological agents available for EphA receptors, we We also find bidirectional changes in gene expression and in designed recombinant immunoadhesins that specifically bind electrophysiological measures of synaptic efficacy that corre- to the receptor binding site of the ephrin-A ligand (antagonist) late with the behavioral results. Thus, EphA receptors and their or the ligand binding site of the EphA receptor (agonist) and ligands are implicated as mediators of plasticity in the adult thus target EphA function. -
Reproducibility of Behavioral Phenotypes in Mouse Models - a Short History with Critical and Practical Notes
Reproducibility of behavioral phenotypes in mouse models - a short history with critical and practical notes Vootele Voikar Neuroscience Center and Laboratory Animal Center, Helsinki Institute of Life Science Correspondence: Mustialankatu 1 G Helsinki, Finland [email protected] Progress in pre-clinical research is built on endorsed by more than 1000 journals so far, reproducible findings, yet reproducibility has awareness of researchers and the quality of different dimensions and even meanings. Indeed, publications have not been sufficiently improved the terms reproducibility, repeatability, and (13-15). In order to facilitate and enhance replicability are often used interchangeably, implementation of the ARRIVE guidelines, a although each has a distinct definition. Moreover, revised version with exhaustive explanation and reproducibility can be discussed at the level of elaborative documentation was recently published methods, analysis, results, or conclusions (1, 2). (16, 17). Despite these differences in definitions and Paradigm shift. Mice and rats are the most dimensions, the main aim for an individual widely used model animals in basic biomedicine. research group is the ability to develop new However, there has been a drastic change in the studies and hypotheses based on firm and reliable relative use of these two rodent species over time findings from previous experiments. In practice (Figure 1). Historically, the rat was the model of this wish is often difficult to accomplish. In this choice for behavioral studies but from the review, issues affecting reproducibility in the field beginning of 1990s a sharp shift from rats to mice of mouse behavioral phenotyping are discussed. took place. Obviously, this was due to rapid Crisis in reproducibility. -
Contcenter for Genomic Regul
CONTCENTER FOR GENOMIC REGUL CRG SCIENTIFIC STRUCTURE . 4 CRG MANAGEMENT STRUCTURE . 6 CRG SCIENTIFIC ADVISORY BOARD (SAB) . 8 CRG BUSINESS BOARD . 9 YEAR RETROSPECT BY THE DIRECTOR OF THE CRG: MIGUEL BEATO . 10 GENE REGULATION. 14 p Chromatin and gene expression .....................16 p Transcriptional regulation and chromatin remodelling .....19 p Regulation of alternative pre-mRNA splicing during cell . 22 differentiation, development and disease p RNA interference and chromatin regulation . 26 p RNA-protein interactions and regulation . 30 p Regulation of protein synthesis in eukaryotes . 33 p Translational control of gene expression . 36 DIFFERENTIATION AND CANCER ...........................40 p Hematopoietic differentiation and stem cell biology..........42 p Myogenesis.....................................46 p Epigenetics events in cancer.......................49 p Epithelial homeostasis and cancer ...................52 ENTSATION ANNUAL REPORT 2006 GENES AND DISEASE .................................56 p Genetic causes of disease .............................58 p Gene therapy ......................................63 p Murine models of disease .............................66 p Neurobehavioral phenotyping of mouse models of disease .....68 p Gene function ......................................73 p Associated Core Facility: Genotyping Unit..................76 BIOINFORMATICS AND GENOMICS ..........................80 p Bioinformatics and genomics ...........................82 p Genomic analysis of development and disease ..............86 -
2009 Program
International Behavioral Neuroscience Society Annual Meeting Program and Abstracts Nassau, The Bahamas June 9-14, 2009 Abstracts of the International Behavioral Neuroscience Society, Volume 18, June 2009 TABLE OF CONTENTS Abstracts....................................................................................................................... 23-66 Acknowledgments................................................................................................................5 Call for 2010 Symposium Proposals....................................................................................7 Advertisements............................................................................................................. 71-75 Author Index ................................................................................................................ 67-70 Exhibitors/Sponsors .............................................................................................................4 Future Meetings...................................................................................................Back Cover Officers/Council...................................................................................................................2 Program/Schedule .......................................................................................................... 8-22 Summary Program ...................................................................................Inside Back Cover Travel Awards......................................................................................................................3 -
Michèle Carlier Brief CV and Publications Born : May, 2, 1947
Michèle Carlier Brief CV and publications Born : May, 2, 1947 Married to Pierre Roubertoux 1child Current position : Emeritus professor, Aix Marseille University Honoray member of the French University Institute Education Master theses: in clinical and social psychology (1968); master thesis in experimental psychology (1969). Thesis (“3ème cycle”) 1972. (University of Paris X Nanterre). Etude différentielle d’une modalité de la créativité: la flexibilité. Differential study on a modality of creativity : the flexibility Thesis (« Thèse d’Etat ») 1986. (University of Paris V René Descartes. L’origine des différences individuelles par la méthode des adoptions. Adoption method and the origin of individual differences Habilitation to direct research in Biology. University of Paris V René Descartes (1990) Teaching experience and Research administration 1) Aix Marseille University (Tenure professor) 2001 – 2011: Behavior Genetics, laterality, mental deficiency, and methodology. Head of the Department 3C (Cognition, Brain, Behavior). Head of the Psychology master 2) School of Education, Orléans University (Tenure Professor) 1997-2001: Developmental psychology, intellectual deficiency. President of the Scientific Committee (1998-2001). Head of the Laboratory CNRS Genetics, Neurogenetics and Behavior (2000-2001). 3) University of Reims (Tenure Professor) 1988-1997: Differential and experimental psychology, behavior genetics, laterality. Head of the Department of Psychology (1989-1992). 4) University of Paris X (assistant then associate professor): 1972-1988: Differential and experimental psychology. Distinctions : Chevalier dans l’Ordre des Palmes Académiques (3/8/1999). Chevalier dans l’Ordre national de la Légion d’Honneur (31/12/2010) President of the Behavior Genetic Association (2003-2006) President of the French Psychological Association (1997-1999) French delegate at the IUPsyS (1994-2004) French delegate at the Scientific comittee of the European Federation of Psychologist’ Association (2005 -2008). -
63-19 Management Challenges, Ku<017A>
Management Challenges in the Era of Globalization Edited by $QQD.XŞPLİVND MANAGEMENT CHALLENGES IN THE ERA OF GLOBALIZATION MANAGEMENT CHALLENGES IN THE ERA OF GLOBALIZATION EDITED BY ANNA KUŹMIŃSKA WARSAW 2019 Reviewers: Prof. Eugene Burnstein – University of Michigan, USA Dr Adam Stivers – Gonzaga University, USA Prof. Alireza Khorakian – Ferdowsi University of Mashhad, Iran Prof. zw. dr hab. Jerzy Kisielnicki – Uniwersytet Warszawski, Poland Prof. zw. dr hab. Grażyna Wieczorkowska-Wierzbińska – Uniwersytet Warszawski, Poland Prof. dr hab. Jerzy Wierzbiński – Uniwersytet Warszawski, Poland Prof. dr. hab. Przemysław Hensel – Uniwersytet Warszawski, Poland Dr hab. Renata Karkowska – Uniwersytet Warszawski, Poland Dr hab. Marta Postuła – Uniwersytet Warszawski, Poland Dr hab. Igor Postuła – Uniwersytet Warszawski, Poland Dr hab. Anna Pawłowska – Uniwersytet Warszawski, Poland Dr hab. Maciej Bernatt – Uniwersytet Warszawski, Poland Dr Marzena Starnawska – Uniwersytet Warszawski, Poland Editorial Supervision: Jerzy Jagodziński Cover design: Agnieszka Miłaszewicz The project “Multicultural Management in the Era of Globalization” is realised by the Faculty of Manage- ment at University of Warsaw on the basis of the legal agreement no POWR.03.02.00-00-I053/16-00 within the Operational Programme Knowledge Education Development 2014-2020 financed through the EU Struc- tural Funds. © Copyright by Wydawnictwo Naukowe Wydziału Zarządzania, Uniwersytetu Warszaw- skiego, Warsaw 2019 ISBN (on-line): 978-83-65402-94-3 DOI: 10.7172/978-83-65402-94-3.2019.wwz.3 Typesetting: Dom Wydawniczy ELIPSA ul. Inflancka 15/198, 00-189 Warszawa tel. 22 635 03 01, e-mail: [email protected] Contents Preface . 7 PART 1 EMPIRICAL PAPERS Who Doesn't Want to Share Leadership? The Role of Personality, Control Preferences, and Political Orientation in Preferences for Shared vs. -
Correlation Not Causation: the Relationship Between Personality Traits and Political Ideologies
Correlation not Causation: The Relationship between Personality Traits and Political Ideologies Brad Verhulst Virginia Commonwealth University Lindon J. Eaves Virginia Commonwealth University Peter K. Hatemi The Pennsylvania State University and University of Sydney The assumption in the personality and politics literature is that a person’s personality motivates them to develop certain political attitudes later in life. This assumption is founded on the simple correlation between the two constructs and the observation that personality traits are genetically influenced and develop in infancy, whereas political preferences develop later in life. Work in psychology, behavioral genetics, and recently political science, however, has demonstrated that political preferences also develop in childhood and are equally influenced by genetic factors. These findings cast doubt on the assumed causal relationship between personality and politics. Here we test the causal relationship between personality traits and political attitudes using a direction of causation structural model on a genetically informative sample. The results suggest that personality traits do not cause people to develop political attitudes; rather, the correlation between the two is a function of an innate common underlying genetic factor. he field of political science is witnessing a re- political attitudes has been found to be largely a function naissance in the exploration of the relationship of latent shared genetic influences (Eaves and Eysenck T between personality traits and political prefer- 1974; Verhulst, Hatemi, and Martin 2010). These find- ences (Gerber et al. 2010; Jost et al. 2003; Mondak and ings cast doubt on the critical foundations necessary for Halperin 2008; Mondak et al. 2010). The belief that per- the assumed causal structure expounded throughout the sonality traits are innate, genetically influenced, and de- extant literature (e.g., Gerber et al. -
42Nd Annual Meeting &
42nd Annual Meeting & Festschrift New from Worth Publishers Behavioral BEHAVIORAL GENETICS - Genetics Behavior Genetics Association A..... PLOMIX loxx C D.Ao Sixth Edition Vname S. K.U.I. The purpose of the Behavior Genetics Association is to promote the scientific study of the it... M. elf MAMBO/ For over four decades, interrelationship of genetic mechanisms and behavior, both human and animal; to encourage Behavioral Genetics and aid the education and training of research workers in the field of behavior genetics; and to has explored the crossroads where Robert Plomin Institute of Psychiatry, London aid in the dissemination and interpretation to the general public of knowledge concerning the psychology and genetics meet, John C. DeFries University of Colorado, Boulder interrelationship of genetics and behavior, and its implications for health and human advancing step by step with this development and Valerie S. Knopik Rhode Island Hospital, education. dynamic area of research as new Brown University discoveries emerge. Available For additional information about the Behavior Genetics Association, please contact the Jenae M. Neiderhiser The Pennsylvania State October 2012, the new edition Secretary, Arpana Agrawal (agrawala @psychiatry.wustl.edu) or visit the website (www.bga.org). University takes its place as the clearest, most up-to-date overview of EXECUTIVE COMMITTEE human and animal behavioral genetics available, introducing October 2012 (©2013) students to the field's underlying principles, defining hardcover 14292-4215-9 Position 2011-2012 2012-2013 experiments, recent advances, and ongoing controversies. President Michael Pogue-Geile Eric Turkheimer President-Elect Eric Turkheimer Carol Prescott Contents the New Edition Past President Irwin Waldman Michael Pogue-Geile Secretary Arpana Agrawal Arpana Agrawal Treasurer Soo Rhee Soo Rhee 1. -
Nicholas Gordon Martin
Nicholas Gordon Martin Table of Contents Birmingham and Beyond by Lindon Eaves Nicholas Gordon Martin by Georgia Chenevix-Trench Nick Martin’s History of the Genetics of Human DZ Twinning by Dorret Boomsma The Genetics of Biochemical Phenotypes by John B Whitfield Nick Martin and the Boulder Workshops by John K Hewitt Nick Martin and the Extended Twin Model by Hermine H Maes Statistical Power and the Classical Twin Design by Pak Sham, Shaun Purcell, Stacey Cherny, Mike Neale, Ben Neale Gene Discovery Using Twins by David Duffy, Rick Sturm, Gu Zhu, Stuart Macgregor Nick Martin by Nathan Gillespie It's in the bloody genes! by David Evans Curly Questions by Sarah Medland The Genetics of Reading and Language by Michelle Luciano and Tim Bates The Genetics of Endometriosis by Grant Montgomery Migraine, Human Genetics and a Passion for Science by Dale R Nyholt Musings on Visscher et al. (2006) by Peter Visscher Genetics of Depression: sample size, sample size, sample size by Enda Byrne, Anjali K Henders, Ian B Hickie, Christel Middeldorp, Naomi R Wray Genetic Risk Prediction of Supreme Cognitive Ability: An Exceptional Case Study by Meike Bartels and Danielle Posthuma Nick Martin as a Mentor- A Perspective by Matthew C Keller Twin Cohorts by Jaakko Kaprio, Dorret Boomsma Human Sexuality by Karin Verweij and Brendan Zietsch SNP-based Heritability- A Commentary on Yang et al. (2010) by Jian Yang The Barbarians are at the Gate! by Pete Hatemi Do People with Lower IQ Have Weaker Taste Perception? A Hidden Supplementary Table in “Is the Association Between Sweet and Bitter Perception due to Genetic Variation? by Daniel Hwang Sociopolitical Attitudes Through the Lens of Behavioral Genetics: Contributions from Dr. -
Curriculum Vita
Jerry Hirsch 1 University of Illinois CURRICULUM VITA Jerry Hirsch Psychology Department University of Illinois at Urbana-Champaign 10/26/07 Revised with additions by Deborah (Zander) Dexter, Secretary to Dr. Hirsch, 1982-2004. Page Biographical Information …………………………………………….. 1 - 4 Research Interests …………………………………………………….. 5 - 8 Publications and Presentations: ……………………………………..... 9 - 41 Refereed Journals of Technical Publications …………………… 9 - 19 Books and Book Chapters ………………………………………. 20 - 23 Reviews ………………………………………………………….. 24 - 27 Commentaries …………………………………………………… 28 - 30 Professional Meeting Abstracts ………………………………….. 31 - 34 Unpublished Papers ……………………………………………… 35 Lecture Notices and Unpublished Talks ………………………… 36 - 37 Newspaper and Journal Articles reporting Hirsch research ………. 38 - 41 Hirsch Correspondence, distributions, attachments ………………….. 42 - 43 Reprints of Others ………………………………………………………. 44 - 46 Biographical Information Jerry Hirsch University of Illinois at Urbana-Champaign Depts of Psychology & of Animal Biology (formerly Ecology, Ethology and Evolution). Born: New York, NY, 20 Sept l922, Army Air Corps 1942-43. Columbia Grammar & Prep Schl, New York City, 1934-38. Johns Hopkins U., Baltimore, MD, 1938-40; U. of Paris, France, 1949-50. B.A. Highest Honors 1952 & Ph.D. 1955, Psych, U. of California, Berkeley. Columbia University 1956-60 -- Asst Prof Psych University of Illinois at Urbana-Champaign 1960-present: Assoc Prof Psychology & Zoology 1960-63 Prof of Psychology 1963 Prof of Zoology 1966 Prof of Ecology, Ethology, Evolution 1976 (EEE renamed Animal Biology 1999) Prof Emeritus (active) 1993 – 2004 Jerry Hirsch 2 University of Illinois Honors and Recognition: Animal Behavior Society: Exec Comm 1967-76, Rep-at-large 1967; Editor of Animal Behaviour 1968-72; 2nd Pres elect, 1st Pres elect, Pres, Past Pres 1973-76; Chairman, then member, of nominating comm 1976-79; Rep to AAAS 1975-93, renewed 1993-96.