BREAK THROUGHS F O R L I F E MESSAGE FROM DR. LARRY COREY, PRESIDENT AND DIRECTOR

When you give to science, Your gifts catalyze our lifesaving breakthroughs One of the privileges of my position as president • Understanding the structure and mechanism significant it was named the science gives back. and director of Fred Hutchinson Cancer Research of highly specific DNA-binding proteins—after breakthrough of the year by Center is to reflect each year on the many ways in investing nearly 20 years in research to unlock their Science magazine—and first- which our latest breakthroughs lead to improved secrets—which might one day be used to repair of-its-kind evidence of a viral he generosity of private benefactors is health for people around the globe. It is both children’s genetic disorders, such as cystic fibrosis, vulnerability that is already rewarding and deeply humbling to know our thalassemia and sickle cell anemia, through a changing the science of HIV critical to eradicating cancer. Donations from T research saves lives. combination of targeted gene correction and stem vaccine development. individuals, businesses and foundations are the Another privilege I particularly enjoy is thanking cell transplantation. These achievements show the many organizations and individuals who • World-leading cancer prevention research to how innovative thinking, genesis of scientific breakthroughs that support the Hutchinson Center. Breakthroughs unravel the links among obesity, inflammation catalyzed by your gifts, happen here because generous benefactors like and cancer risk, helping the medical community brings hope to patients and their families. Your save lives. Your contributions fund you give our pioneering researchers the freedom begin to tackle the emerging epidemic of obesity- contributions sustain the Hutchinson Center’s innovative early stage research, to create and explore innovative ideas with the related cancers. unique scientific culture—one that fosters ingenuity, potential for profound impact. • Two unprecedented discoveries—one that risk-taking and collaboration among the world’s top recruitment of the world’s top scientists, This year that exploration led to major strides— sheds light on why some prostate cancers are researchers to produce major medical advances. new research technologies, and services for not just in one or two areas, but across the entire lethal and another that reveals how a single On behalf of everyone at the Hutchinson breadth of our research. Some of our recent genetic abnormality leads to a form of muscular Center, I extend my sincere thanks to you patients and families in need. In the articles that advances, highlighted in this annual report, include: dystrophy—that researchers can leverage to craft for helping us save lives by investing in our • Creative new solutions to treatment challenges new prevention, detection and treatment strategies breakthrough research. follow, look for this icon, a symbol of the —including bold efforts to extend the curative power for these diseases, and potentially many others forward momentum that private benefactors deliver of bone marrow transplantation to wider patient as well. populations and a game-changing breakthrough in • The finding that drugs used to treat AIDS to accelerate scientific breakthroughs for life. pancreatic cancer treatment. can actually prevent HIV’s spread—a result so

CONTENTS

Message from the President 1

2012 Research Breakthroughs 2

On the cover: Drs. Barry Stoddard and Amanda Mak made a potentially lifesaving Message from the Chair 16

breakthrough this year, which they are already translating into possible treatments Private Contributors 17

for genetic diseases. Financial Summary 24

1 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT The curative power of umbilical cord blood

Christian Beattie is a competitive cyclist who, find a donor match within their families or through particularly difficult to over the course of a long career, has raced with international bone marrow registries. For most transplant adult patients the sport’s biggest names and in the world’s most ethnic minorities and people of mixed heritage, with cord blood. prestigious events. But last year, the 39-year-old the chances of finding a donor are even lower. Delaney’s research from Kansas City, Mo., went from winning races to “When all else failed, I knew I had to get to Seattle,” has broken through this feeling “not right.” he said. barrier by developing a Beattie was diagnosed with acute myelogenous He did just that and is now reaping the benefits way to multiply the tiny leukemia. His best hope for a cure was a of Delaney’s lifesaving breakthrough. number of umbilical cord bone marrow transplant, the Nobel Prize-winning Delaney is pioneering research focused on the blood cells 200-fold in the treatment developed at Fred Hutchinson Cancer healing powers of umbilical cord blood transplants. laboratory so they can be transplanted in adults. Research Center. Collected from the discarded placenta after a baby Beattie received an expanded cord blood is born, cord blood is rich in helpful cells that have transplant and left the hospital in just 10 days, with the potential to cure cancer. the underpinnings of a healthy immune system—far “It really is the ultimate recycled product,” faster than with a traditional transplant and with Delaney said. “You can give life to a child and by few side effects. But, like 40 percent of all transplant candidates, reusing what is normally thrown away, save the life Now, Delaney and colleagues are taking their Beattie was unable to find a well-matched donor of someone else.” work further, developing an approach to cord blood with enough shared biological characteristics to Because the cells found in cord blood are less transplants which doesn’t require patient-donor make a transplant viable. After exhausting all other developed than adult blood stem cells, they don’t matching. Under this new study, she is working treatment options, a doctor in Kansas gave him need to be as closely matched to a patient, allowing to develop expanded, “off-the-shelf” cord blood slim odds of reaching the age of 40. a match for nearly all patients. But cord blood units that can be frozen and made available Then a friend showed him an article about transplantation has one problem—a single unit to all patients. Dr. Colleen Delaney’s research at the Hutchinson contains so few cells that a patient is vulnerable “I want people to know everyone has a match,” Center. Her efforts were a ray of hope to Beattie, to infection for a long time before the transplant said Beattie, whose plans now include cycling into one of the 16,000 people each year who can’t can rebuild the immune system. This has made it his 40s and beyond.

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3 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT Significant breakthrough in pancreatic cancer treatment

Pancreatic cancer is a formidable foe. It to its advanced stages. This powerful tool has found a way around the protective shell: Using their grows fast and spreads quickly, often before any enabled researchers to get closer to understanding mouse model, the team employed an enzyme symptoms appear. And because of its notorious pancreatic cancer’s defenses better than ever that digests and removes the scar-like tissue resistance to treatment, 97 percent of patients before, opening the door to more effective ways to around the tumor. With the tumor defenses aren't alive five years after diagnosis. detect and treat the disease. breached, the chemotherapy can enter and attack Dr. Sunil Hingorani understands all too well the Using this model, Hingorani recently made two the cancerous tissue. pain inflicted by a pancreatic cancer diagnosis. potentially momentous discoveries. He unraveled The results were so successful, Hingorani He lost his father to the secrets of how pancreatic tumors thwart worked to get clinical trials fast-tracked. the disease, leading therapies and then developed a way to penetrate Hingorani, with his unwavering dedication to him on a personal and those defenses. patients, is now leading an international trial for professional mission to Most cancerous tumors grow blood vessels to patients with metastatic pancreatic cancer, using find ways to beat it. deliver nutrients and oxygen to them, providing an His dedication is entrance for chemotherapy drugs to gain access to paying off with some the tumor. of the most significant In pancreatic cancer, however, Hingorani contributions in the discovered that pancreatic tumors build a tough, a combination of the enzyme and chemotherapy. fight against pancreatic protective shell—similar to scar tissue—that Already, his work is bringing new hope to cancer—including a physically keeps chemotherapy from entering the patients at Seattle Cancer Care Alliance, the breakthrough discovery that could change the way tumor. This revelation explains why treatments treatment arm of the Hutchinson Center. it is treated. that eliminate other cancers are ineffective here; “We’re not just treating a disease,” he said. A few years ago, Hingorani developed the the cancer drugs never reach the pancreatic “We are treating a person. Patients are not first mouse model that faithfully mimics human cancer cells. statistics. We think about this disease day pancreatic cancer, from its precancerous inception With this knowledge, Hingorani and colleagues and night.”

A generous donation from Maryanne Tagney-Jones and David Jones challenged Dr. Sunil Hingorani, pictured with Dr. Vikas Goel, right, unraveled the secrets of how pancreatic tumors a community of supporters, and collectively their gifts helped make possible thwart chemotherapy and developed a way to penetrate those defenses. These breakthroughs are Dr. Sunil Hingorani’s potential breakthrough in pancreatic cancer treatment. so significant, he is fast-tracking this new treatment to help patients with metastatic pancreatic cancer.

5 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT Dr. Peter Nelson has discovered genetic mutations in aggressive prostate cancers, providing clues to why some prostate cancers are lethal and become resistant to treatment. This could lead to individualized treatments targeting the genetic drivers of these cancers.

Targeting the genetic drivers of lethal prostate cancers

Nearly all men will develop prostate cancer— lethal, and potentially could lead to prevention The genetic knowledge of these lethal cancers if they live long enough. Yet its progression methods, screening tests for early cancer detection could enable researchers to tailor treatments that remains difficult to predict. In some men, the or drug targets to slow or halt cancer growth, target the genetic drivers of the cancers. disease lies dormant for many years; in others, Nelson said. Nelson likens the aggressive tumors to Ferrari tumors rage in spite of treatment, spreading to the The scientists found these “hypermutated” racecars. “If we can identify the molecular engines bones, where a cure is exceedingly rare. cancers after mapping the that drive the cancers, we may be Identifying new, more precise ways to genomes of 23 lethal and drug- able to block the fuel that runs individualize care for the disease’s varied forms resistant forms of the disease, those engines, which could slow or is one of the major challenges confronted by the which until now had been poorly stop the cancer from progressing,” Hutchinson Center’s Dr. Peter Nelson, one of the defined. he said. “The most interesting finding Nelson is hopeful this line was the discovery of the three of research could be one of aggressive tumor types, which the first successful steps to treat had 10 times the number of aggressive prostate cancer through nation’s leading prostate cancer researchers. mutations compared to the other precision medicine. This year, Nelson and colleagues at the advanced prostate cancers we The next goals are to expand Hutchinson Center and University of Washington studied,” Nelson said. “That was this research to other cancers discovered three types of aggressive prostate very surprising and unusual. and to help define its use in tumors that mutate at a much faster rate than We don’t know the cause of these determining which patients to treat others and become resistant to treatment. hypermutated tumors, but the frequency of and which to watch closely. These The discovery of these genetic mutations the mutations suggests these tumors evolve very are the types of big ideas Nelson and his research provides clues to why some prostate cancers are rapidly to develop resistance to therapies.” team are undertaking.

Dr. Peter Nelson’s discoveries on lethal prostate cancers were fueled by gifts from the Thomas C. Wright Foundation, the Richard M. Lucas Foundation and the Prostate Cancer Foundation.

7 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT Sally von Bargen lost 75 pounds, nearly one-third of her body weight, during an exercise and diet study conducted by Breaking the link between Dr. Anne McTiernan. Her transformation obesity and cancer illustrates how Hutchinson Center researchers are at the forefront of Sally von Bargen once described herself as Von Bargen’s transformation illustrates how isn’t as big for most cancers, but it’s so prevalent constant, low-grade inflammation, which can cause understanding— and potentially a “jolly, overweight, grandmother type” who Hutchinson Center researchers, like McTiernan and that it will have a huge impact.” progressive damage linked to a variety of health preventing— obesity-fueled cancers. watched her mother struggle with breast cancer her colleague Dr. Mario Kratz, are at the forefront McTiernan’s research measures how exercise problems, including cancer, heart disease and and her father battle heart disease and diabetes. of understanding—and potentially defusing— and weight loss affect the levels of estrogen, diabetes. Overweight since childhood, she knew she was on what is becoming a new inflammation and other A current study investigates how sweetened a slippery slope toward weight-related illnesses, cancer epidemic. Being so-called “biomarkers” linked to beverages, such as including cancer. overweight or inactive cancer. Her studies have found soda with high-fructose Then last year, she signed up for a Hutchinson is known to increase a that people who get regular, corn syrup, impact Center study led by Dr. Anne McTiernan person’s risk of some moderate exercise—even later levels of C-reactive examining diet and exercise in overweight of the most common in life— can reduce their risk protein (CRP) in a postmenopausal women. cancers, including for breast cancer, colon cancer, person’s blood, which colorectal cancer, breast diabetes and other major signals the presence of cancer and certain diseases. This year alone, she inflammation. prostate cancers, and is published findings from several “Our pilot studies also linked to cancers of studies that explain how weight showed that some the esophagus, pancreas, loss can reduce breast cancer sweeteners could cause a For the scientifically rigorous study, von Bargen’s kidney and gallbladder. risk and describe evidence-based factors that significant increase in a person’s CRP levels in just calorie intake was scrutinized, her movements The threat is so severe that McTiernan, whose contribute to successful weight loss. over a week,” Kratz said. “If that happens in eight meticulously recorded, her body fat and bone numerous groundbreaking studies over the last Kratz has also made significant strides with days, imagine what it does over your entire life—it density carefully scanned. Her study goal was to 20 years have illuminated much of what we now some of the world’s most innovative feeding studies, could have a substantial impact on your risk of lose 23 pounds. She lost 75, nearly one-third of her know about obesity and cancer risk, likens obesity which he believes will redefine the guidelines of developing many kinds of chronic disease.” body weight. to another insidious problem that took decades what we should and shouldn’t eat to reduce our Kratz’s studies could ultimately reshape dietary “I can say—unequivocally—that I will never gain to diminish. cancer risk. His research focuses on inflammation, guidelines to reflect new knowledge about which that weight back again because now I know how to “Obesity is almost like the new smoking,” one of the big keys in the obesity-cancer equation. foods affect cancer risk. It’s all part of stopping exercise and eat to be healthy,” she said. McTiernan told the Los Angeles Times. “The effect Obesity, he explains, puts the body in a state of obesity-related cancers before they strike.

The cancer prevention research of Drs. Anne McTiernan and Mario Kratz is supported by the Hutchinson Center's President’s Circle, a group of individuals and corporate benefactors whose aggregate funding speeds the development of innovations in all areas of our research.

9 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT Using a unique form of computational and X-ray Dr. Barry Stoddard’s breakthrough was aided by Dr. Phil Bradley’s crystallographic analyses, a team of researchers, computer modeling of the TAL protein, pictured behind Stoddard. including Drs. Amanda Mak and Barry Stoddard, solved the structure of a unique type of DNA-targeting protein. This will enable them to engineer the protein Correcting genes that cause inherited diseases to fix genetic diseases, such as sickle cell anemia and cystic fibrosis. In his Hutchinson Center laboratory, structural pain and leads to a host of chronic, sometimes fatal Targeted gene correction biologist Dr. Barry Stoddard is engineering health problems. with TAL effectors involves directly repairing biochemical guided missiles to fix genetic diseases. Bender, an affiliate researcher at the Hutchinson disease-causing genes, which promises more After almost 20 years analyzing unique types Center, is an associate professor of pediatrics at predictable results without harmful side effects of proteins that seek out and bind to precise gene the University of Washington and director of the because the TAL effector can lock onto precisely the targets, Stoddard’s laboratory made a potentially sickle cell clinic at Odessa Brown Children’s Clinic. right gene. lifesaving breakthrough this year, which they After Bender identified a DNA sequence associated In nature, TAL proteins exist in a type of bacteria immediately began translating into tools to provide with the disease, Stoddard engineered a targeting that infects plants such as soybeans, tomatoes and better care for patients. protein to moderate the genetic defect. peppers. The bacteria use them to target specific Stoddard and his team of researchers were able Targeting sickle cell is just the first step. By DNA sites in the plants. to take this leap forward when they determined the determining the TAL effector structure, Stoddard Stoddard’s breakthrough enables scientists to has opened the see exactly how TAL effectors recognize specific door to alter the DNA sequences and bind to them. “By solving their protein for a variety structure, we can manipulate TAL effectors to find of biotech and human DNA targets, stay active longer, or deliver three-dimensional structure of a protein called a medical applications. “The upcoming years will see additional molecules that drive a desired change in TAL effector— transcription-activator-like effector— an explosion in the development and use of TAL the gene target,” he said. which, along with a group of DNA-targeting enzymes effectors for corrective gene therapy,” he said. This is exactly what Stoddard envisioned when called homing endonucleases, can be used to treat Although still in the developmental stage, he began studying gene targeting proteins almost genetic diseases. Stoddard and colleagues are now targeted gene correction is a giant advance from 20 years ago— and what he and Bender are doing attempting to do just that, by combining both types existing gene therapy, which involves introducing a to correct the genetic defect that causes sickle of proteins to potentially treat and cure inherited corrected version of a defective, disease-causing cell anemia. disorders, such as cystic fibrosis and sickle cell gene with the hope that it assumes the role of the “We’re getting close to being able to test it anemia through a technique known as targeted defective gene. The problem is that the corrected on human cells in the lab. If it works, we’ll move gene correction. gene doesn’t always find its way to a safe or useful forward with improved versions,” said Bender. “Our Already, he’s collaborating with Dr. M.A. Bender location in a patient’s DNA—a drawback that limits ultimate hope is that we can dramatically reduce to develop therapies for sickle cell anemia—a the therapeutic benefits and can cause harmful the symptoms of sickle cell anemia — and possibly devastating blood disorder that causes excruciating side effects. even provide a cure.”

Dr. Barry Stoddard’s advances in targeted gene correction were made possible in part by a generous gift from the Cuyamaca Foundation.

11 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT Hope for patients with a common muscular dystrophy

It is an insidious muscle disease whose and molecular geneticist Dr. Stephen Tapscott “There was not a ‘eureka’ moment, but rather symptoms often begin in the mid-teens. Arm broke through the decades-long stalemate with it played out over several years of hard work weakness and shoulder deformities are common. In FSHD. This year, they identified the genes and that gradually revealed the answers. It has been some cases, it can lead to hearing loss, abnormal proteins that damage muscle cells, as well as the extremely gratifying to put all the different pieces heartbeat and leg weakness. Some patients mechanisms that can cause the disease. together and see a bigger picture reveal itself that become severely disabled and wheelchair-bound. These discoveries open the door for developing could have a profound impact on patients suffering It is one of the most common inherited a biomarker-based diagnostic test and future from this disease.” forms of muscular dystrophy, known as FSHD— treatments for FSHD—as well as for potential new In addition, Tapscott’s research has the potential facioscapulohumeral dystrophy— named for the ways to treat cancer. to lead to a vaccine to treat cancer. muscles of the face, Tapscott’s team first showed that it took two One of the major challenges in developing shoulder blade and upper genetic changes on chromosome 4 to cause cancer vaccines is finding immune targets present arm it attacks. FSHD. Later, they determined that FSHD and other a certain protein called DUX4 muscular dystrophies have —normally found in germ cells proven to be extremely that give rise to sperm in males confounding for biomedical and egg development in females—was abnormally in cancer cells but absent in healthy cells. DUX4, researchers, yielding so active in muscle cells, causing muscle mayhem. the protein Tapscott identified as the cause of little information that the Because the protein is not supposed to be active FSHD, induces the expression of proteins that are very idea of coming up with in mature muscle tissue, it blocks normal functions targeted by the immune system in several types drugs to treat them has and regeneration of muscle cells, leads to muscle of cancer. Now, he and Dr. Stanley Riddell are seemed like a dream. For more than two decades, cell death, and likely triggers an immune response, working to determine whether they can use researchers have known that FSHD is caused by with the body attacking its own muscle cells. DUX4 to stimulate the immune system against a genetic mutation, but no one understood the With this information in hand and newfound these proteins. mechanics of the disease and exactly what was interest from pharmaceutical companies, Tapscott “This knowledge gives us a way to manipulate causing the muscles to deteriorate. hopes that new therapies and biomarker-based the expression of these proteins, opening the door Then, after several years of intensive research, diagnostic tests for FSHD patients are not far off. to developing a new type of vaccine capable of a team led by Hutchinson Center neurologist “Getting here was not easy,” Tapscott said. targeting multiple cancers,” Tapscott said.

Dr. Stephen Tapscott’s research on FSHD and cancer is supported by a pilot grant from the Hutchinson Center’s Hartwell Innovation Fund, Dr. Stephen Tapscott’s team broke a decades-long stalemate with a common form created by Craig and Marie Mundie, which allows scientists to rapidly respond to novel and sometimes unexpected research opportunities. of muscular dystrophy when they identified the mechanisms that cause it. This opens The Geiger Family Foundation and Orin and Charlene Edson are longtime supporters of the fund. the door for future treatments for the disease and, potentially, some cancers.

13 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT Dr. Ying Chen and colleagues designed and analyzed Discovery of an HIV vulnerability is advancing vaccine development the groundbreaking study that proved the drugs used to treat AIDS can prevent the spread of HIV. In 2009, the HIV research field was rocked infectious disease researchers of any U.S. cancer those who had not. The team found that uninfected by the results of a vaccine study conducted in center and is a global leader in HIV research. Our people had higher levels of an antibody that binds Thailand, the first HIV vaccine success in the scientists manage the world’s largest HIV vaccine to one tiny spot in HIV’s bumpy outer shell. epidemic’s 30 years of existence. Finally, scientists program, the HIV Vaccine Trials Network. Gilbert and his Hutchinson Center collaborators had a real starting point to fight this devastating Statistician Dr. Peter Gilbert is an expert at also found the HIV strains that slipped past the disease. detecting “correlates of protection” in HIV vaccine Thai Trial vaccine had mutations in the exact spot The vaccine in the RV144 HIV study — often trials. These correlates are signals from our where the antibody would normally bind. called the “Thai Trial” — protected 31 percent of immune system that it is successfully protecting us The team’s findings are the first evidence of heterosexuals from new HIV infections, a huge step from infection. Identifying correlates of protection this kind of weakness in HIV’s seemingly bullet- forward in the hunt for a successful vaccine against could dramatically speed up trials to test new proof armor. the virus that causes AIDS. candidate HIV vaccines and enable scientists to “If this is, indeed, a real correlate of protection, But the trial’s partial success meant nothing build a vaccine that specifically elicits those signals. then it changes everything,” Gilbert said. without understanding why this vaccine succeeded Gilbert, collaborating with a team of HIV vaccine Our vaccine researchers are already designing where others had failed. This year, Fred Hutchinson researchers, including the Hutchinson Center’s their upcoming trials to focus on this important Cancer Research Center scientists helped answer Dr. Julie McElrath and scientists at Duke University, antibody. that question. led an effort to compare the immune signals of Thai “This is not just academic data,” Gilbert said. The Hutchinson Center has the largest team of Trial participants who had become infected and “This is changing the science of HIV vaccines.” HIV treatment as prevention: breakthrough of the year

These landmark HIV breakthroughs were made possible in part by private support, including grants Stopping— or even slowing—the AIDS pandemic HIV, the other without — participated in the study been inconceivable even a year ago,” wrote from the Bill & Melinda Gates Foundation and a planned gift from the Richard W. Weiland Estate. has proven to be a difficult undertaking for more spanning nine countries on four continents. The Dr. Bruce Alberts, editor-in-chief of Science. “This than three decades. But this year a team of results showed that the early use of antiretroviral is not to say that we can abandon the search for researchers, including biostatisticians from the drugs reduced HIV transmission to uninfected an AIDS vaccine. Nor will profound change come Hutchinson Center, heterosexual partners by a stunning 96 percent. overnight from the promise of using treatment made an advance with Half of the HIV-positive participants were given as prevention. But for its role in making success immediate lifesaving antiretroviral drugs at the outset. The dramatic conceivable, we have chosen the results of this trial impact. The researchers effectiveness of the drugs— a 20-fold reduction as our breakthrough of the year.” showed drugs used to treat AIDS can prevent the of HIV transmission to uninfected partners and Hutchinson Center biostatistician Dr. Ying spread of HIV, the virus that causes AIDS. a 41 percent decrease in serious HIV-related Chen, the second author, and his colleagues in the The HIV Prevention Trials Network study health problems for infected partners —settled a Center’s Vaccine and Infectious Disease Division known as HPTN 052 was so profoundly significant, long debate over whether HIV treatment could do played a pivotal role in the study. They helped Science magazine chose it as the world’s double-duty and cut transmission rates. design, monitor and analyze the study and provided Dr. Peter Gilbert and colleagues have found scientific breakthrough of 2011. “The results have galvanized efforts to end the vital statistical support, processing more than a half evidence of weakness in HIV’s armor, which is More than 1,700 couples—one partner with world’s AIDS epidemic in a way that would have million forms of study participant medical data. changing the science of vaccine development.

15 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT MESSAGE FROM STEVE DAVIS, CHAIR, BOARD OF TRUSTEES, FISCAL YEAR 2012 MAKING RESEARCH PROGRESS POSSIBLE

PRIVATE CONTRIBUTORS FISCAL YEAR 2012

Without research, there are no cures Fred Hutchinson Cancer Research Center relies on private contributions to accelerate scientific advances. This crucial support aids in the pursuit of novel ideas, sustains promising research and enables scientists to explore new directions as they emerge; all paramount in the fight against cancer and related diseases. We are grateful to each of the 22,824 donors Without research, there are no cures. That’s Your support is critical to our ongoing efforts tomorrow’s therapies to today’s patients. who provided $28.8 million in contributions and in-kind gifts between July 1, 2011, and June 30, 2012. Each of the individuals, corporations, foundations and organizations listed below contributed $1,000 or more within the 2012 fiscal year. We are grateful for the generous investment from all of our supporters in the Hutchinson Center's relentless pursuit to improve the to eradicate cancer and other life-threatening When you give to science, science why every day for nearly 40 years, Fred Hutchinson prevention, detection and treatment of cancer and related diseases. Cancer Research Center’s investigators have diseases. It is your investment that propels gives back, and this report illustrates

dedicated themselves to world-class science. The Hutchinson Center science forward, accelerating how Hutchinson Center researchers Nobel Laureates Circle Bob and Eileen Gilman Family Herman E. Tenzler Estate Paul Edwin Melcher Estate Mikal and Lynn Thomsen PC* The Nobel Laureates Circle recognizes The GM Foundation Dr. and Mrs. E. Donnall Thomas M. J. Murdock Charitable Trust United Way of King County payoff has been immense—breakthroughs in progress along the entire research pipeline, are turning your investment into contributors who have made cumulative gifts of Calvin A. Gorman Trust Mikal and Lynn Thomsen Safeway Inc. PC W. M. Keck Foundation $1 million or more. These key benefactors are Alice Coulon Hanson Hazel Johnson Toly Estate The Seattle Foundation Chrystal H. Wagner Estate virtually every field of cancer research, discoveries whether by funding an early stage study, nurturing innovation. We thank you for your permanent members of the Circle which was John J. and Katherine A. Harnish Bonnie and Jim Towne Sophie Sussman Estate Doug and Maggie Walker PC* established in 2001 to honor the Hutchinson Lee Hartwell and Theresa Naujack Hartwell Turner Construction Wayne D. Kuni and Joan E. Kuni Foundation that save thousands of lives each year. And the the career of a talented young investigator, or partnership and for inspiring all of us Center’s Nobel Prize recipients, Drs. E. Donnall The Hearst Foundations United Way of King County $100,000 - $249,999 Zevenbergen Capital Investments LLC PC* Thomas (1990), Lee Hartwell (2001) and Linda Bob and Pat Herbold W. M. Keck Foundation The 3725 Fund of Oregon Community promise for the future is even greater. jump-starting a clinical trial that will bring with your generosity. Buck (2004). By giving at this level, members Arthur P. Holm Estate Richard W. Weiland Estate Foundation $50,000 - $99,999 of the Nobel Laureates Circle are at the Howard Hughes Medical Institute American Diabetes Association Alaska Airlines forefront of philanthropic leadership and make Yvonne Twining Humber Estate Nobel Laureates Circle membership includes The Anderson Foundation PC* Alex’s Lemonade Stand Foundation for a significant impact on the Center’s mission Immunex three anonymous benefactors. The Broad Foundations Childhood Cancer to eliminate cancer and related diseases as J. Orin Edson Foundation Marian Bulgarelli Estate Alfred P. Sloan Foundation causes of human suffering and death. Jacob Green Charity Golf Classic $1,000,000 and up Gary and Catherine Bylund PC* American Heart Association Erna M. Jorgensen Trust Bezos family PC Cancer Research Institute Amgen PC Madeline and Howell E. Adams, Jr. José Carreras International Leukemia Bill & Melinda Gates Foundation Roger and Gloria Crouch PC* Anduin Foundation PC Mr. Paul G. Allen Foundation Howard Hughes Medical Institute CRP-Santé Margaret W. Berg Estate American Cancer Society Nelda Kleinschmidt Leukemia & Lymphoma Society Delta Tau Delta Fraternity Yvonne M. Betson Trust - Jeff and American Heart Association The Leukemia & Lymphoma Society Seattle Children’s Clairmont L. and Evelyn S. Egtvedt Ethel Maxwell PC* Amgen Life Sciences Discovery Fund The Ellison Medical Foundation Mike and Jackie Bezos The Anderson Foundation Listwin Family Foundation $500,000 - $999,999 Friends of FSH Research Beverlee A. Brown Estate Robert M. Arnold LIVESTRONG Burroughs Wellcome Fund Edward and Karen Fritzky Family PC* Costco Wholesale PC YOUR SUPPORT HELPS Avon Foundation for Women Lymphoma Research Foundation Charles E. Stuart Charitable Foundation The G. Harold & Leila Y. Mathers Charitable Cuyamaca Foundation Bezos family Lucille P. Markey Charitable Trust Damon Runyon Cancer Research Foundation Foundation Nellie Marie Danner Estate Bill & Melinda Gates Foundation Mr. John A. McCone and Nelda Kleinschmidt Estate PC Giles W. and Elise G. Mead Foundation James R. Degarimore Estate Burroughs Wellcome Fund Mrs. Theiline Pigott McCone Listwin Family Foundation PC Mary M. Green Estate Holly and Eric Dillon PC* Canary Foundation Paul Edwin Melcher Estate The Norcliffe Foundation The Helen Hay Whitney Foundation The Employees Community Fund of Boeing Cancer Research Institute Microsoft Corporation Jack and Sylvia Paul Hyundai Hope on Wheels Puget Sound Cell Therapeutics, Inc. Moneytree, Inc. Dorlesca Hazel Ryan Estate J. Orin Edson Foundation PC Colin Faulkner FUND–AND FIND– Charles E. Stuart Charitable Foundation John and Susie Morganti Estate St. Baldrick’s Foundation Jacob Green Charity Golf Classic David Worthington Garner Trust Costco Wholesale The Moyer Foundation Susan G. Komen for the Cure The John C. and Karyl Kay Hughes Patricia ‘Diddy’ Pollock Goldberg Trust Mylo and Marion Charlston Craig and Marie Mundie Myrna F. Weaver Estate Foundation PC* Rochelle Greenberg PC Mr. and Mrs. Fenwick J. Crane M.J. Murdock Charitable Trust Erna M. Jorgensen Trust Mr. David W. Hansen and Ms. Trish M. King PC* Roger and Gloria Crouch Muscular Dystrophy Association $250,000 - $499,999 The Kuni Family The Hope Foundation Damon Runyon Cancer Research Foundation The Norcliffe Foundation American Association for Cancer Research Rae and Mark Lembersky PC* Imperial College London Delta Tau Delta Fraternity Dorothy and Everett O’Neill American Cancer Society Life Sciences Research Foundation International Vaccine Institute Peter S. and Sandra W. Dyer The Paul G. Allen Family Foundation Canary Foundation PC Lupus Research Institute Ralph C. Jacobson Estate J. Orin and Charlene Edson James B. Pendleton Charitable Trust Gloria M. Congdon Estate Melanoma Research Alliance Mike and Diane Johansson PC* Clairmont L. and Evelyn S. Egtvedt Prostate Cancer Foundation The David and Patricia Giuliani Family The Moyer Foundation C. Greg Markham Estate CANCER The Ellison Medical Foundation James and Sherry Raisbeck Foundation PC* Multiple Myeloma Research Foundation Martin-Fabert Foundation Entertainment Industry Foundation Richard C. Goldstein Private Foundation Dorothy W. Day Trust Carol-Ann O’Mack and John Deininger PC* Merck & Co., Inc. The Eucalyptus Foundation Jim Roberts and Pam Becker J. Orin and Charlene Edson PC Rett Syndrome Research Trust National Breast Cancer Foundation, Inc. Fannie E. Rippel Foundation Safeway Inc. Entertainment Industry Foundation The Rona Jaffe Foundation PC National Multiple Sclerosis Society Friends of José Carreras International James G. Scripps Estate The Eucalyptus Foundation PC Sarcoma Alliance for Research Through The Pew Charitable Trusts Leukemia Foundation The Seattle Foundation Foundation for the National Institutes of Health Collaboration Phi Beta Psi Sorority David Worthington Garner Trust Sheldon Manufacturing, Inc. LIVESTRONG Searle Scholars Program Platt Family PC* Bill and Melinda Gates Susan G. Komen for the Cure LUNGevity Foundation Thomas C. Wright Foundation PC Quest for Truth Foundation PC

BREAKTHROUGHS. 17 | FRED HUTCHINSON CANCER RESEARCH CENTER 2012 ANNUAL REPORT PRIVATE CONTRIBUTORS FISCAL YEAR 2012

Reata Pharmaceuticals Inc. Wilson Construction Company Mr. and Mrs. Robert L. Gerth PC* Sujal and Meera Patel PC $5,000 - $9,999 Charlie and Nancy Hogan Willow M. Rosetti Estate Mr. Robert S. Angel Mr. Thomas Bookman Mr. John P. Chilcote Paula J. Rose Estate Winebow, Inc. Dr. and Mrs. Kenneth Gitlin PC Harry Jonathan Pearce PC* Francine Horn Abrams Mr. Norman E. Hubbard Russell Investments Angelo’s Restaurant Mrs. Gertrude R. Both Ms. Lisa D. Chinlund Milton and Ruth Rubin PC* Wyner/Stokes Foundation D. Wayne and Anne E. Gittinger PC Mark and Nancy Pellegrino PC* ACBL Charity Foundation Mr. and Mrs. Lyman W. Hull Jack Schenker Charitable Trust Carl and Andrea Anton Ms. Catherine A. Bourdeau The Chisholm Foundation Mr. Eugene G. Sivertson ZGF Architects LLP PC* glassybaby Perkins Coie LLP PC The Adam J. Weissman Foundation Integrated Archive Systems Seattle Metropolitan Jill Argo Deborah Boutinen Henry Chiu IN Brett Storie Family PC Kari Glover and Thad Alston PC Wayne and Christine Perry PC The Adrian Hanauer Foundation Nea Lynn Ireland Chris and Kristin Secreto Dr. and Mrs. Jay Arlick Diane E. Bowers Lawrence N. Christian Estate Holly and Henry Wendt PC $10,000 - $24,999 Charles Goggio, Jr. PC Pete and Wilma Olsen Foundation PC* Alliance Project Advisors John M. Gilbertson Foundation Sheraton Seattle Hotel Debbie and Ron Arons Brackets for Hope, Inc. Mr. and Mrs. LeRoy R. Christiansen O. Meredith Wilson Trust Aaron and Betty Gilman Family Foundation PC Google Inc. John B. Piacentini Family PC* Mike and Sumi Almquist Johnson & Johnson Family of Companies Andrew Short Bob and Clodagh Ash Mr. Dennis Brass Chubb & Son Inc Joseph and Janet Zinn PC* Aequitas Capital Management PC Mark Groudine and Cynthia Putnam PC* Paul and Beth Picardo PC* Chap and Eve Alvord Lisa Johnson of Johnson International Woody and Karen Sillifant Mr. Larry Asher Braun Consulting Group Zita M. Chubbuck Alexandria Real Estate Equities, Inc. Nancy Gudmundson PC PlanetZ/Echelon Gran Fondo Kathleen Arneil Industries Silver Cloud Inns & Hotels Alan and C.J. Ashton Robert and Renee Braun Ki-Hyun Chun $25,000 - $49,999 American Genetic Association Donald Guthrie and Candace Tkachuck PC* Dean and Gwenn Polik and Valerie Polack PC* Mr. and Mrs. Ronald R. Bailey JP Morgan Chase Bank SiRAS.com Edith and Ray Aspiri Mrs. Pamela A. Brazier Charlie Chung IN* Arleta Rae Allen PC Mark and Susan Anderson Erik and Susan Hansen PC* Precision Electric Group, Inc. Mary M. Baker Peter and Angela Junger Phil Smart, Jr. and Sally Raines-Smart AT&T Community Giving Program Aaron Bregel IN* Gus Churchill American Brain Tumor Association Ric and Kaylene Anderson PC* John and Suzanne Hansen PC Tim and Kathy Proctor PC Ballard Technology, Inc. Arnold Kas Mr. Laurence H. Smead Employee Donation Herb Bridge and Edie Hilliard Cima Inc Athena Partners Foundation PC Dr. Frederick and Dita Appelbaum PC* Janine K. Harnish PC* Andre and Lisa Radandt PC Bank of America Kate Shea Foundation Doug Smith and Mary Templeman-Smith Michael Atalla IN Randall R. Broad IN Mr. J. Terence Clark Bayley Family Foundation PC* Robert M. and Pattie Arnold PC John and Darellane Harrison James V. Ramsdell, Jr. PC BarclayDean Kaye-Smith Snohomish County Employees Charitable Ater Wynne LLP Rodel Broas and Elizabeth Sumption IN* Randy and Judy Clark Carl and Renée Behnke PC* The Aven Foundation PC Deborah and Eric Haug PC Donald L. Redburn, Jr. Estate Barclays Capital Kinzer Real Estate Services Campaign Mr. and Mrs. John J. Atwood, Jr. Robert L. Brock, PhD Simon Clarke and Alice Burden IN Rod Belcher Bill and Pam Ayer PC Hal and Jerry Haynes Richard C. Goldstein Private Foundation PC Mark and Lark Barnum Judy Kornell Soaring Heart Natural Bed Company Mr. and Ms. John K. Austenfeld Daniel Bronson IN Deborah Cleveland Elisabeth Bottler PC* Bank of America Merrill Lynch Marco J. Heidner Charitable Trust Mr. and Mrs. C. Willis Ritter Barton Family Foundation Lane Powell PC Sara Somers Ed and Linda Averett Michele Brooks IN Coldstream Capital Management Brandon’s Goal Foundation Charles and Linda Barbo Mike and Judi Hickey PC* Jim Roberts and Pam Becker PC* Bayley Construction Mr. and Mrs. Douglas C. Lawrence Joan Steier and Barbara Blywise Mr. and Mrs. Alfred A. Baffa Bradley and Amy Brotherton IN Mr. Frank E. Colson Barbara Cosgrove and Frank Yandrasits PC Joe and Karyn Barer PC Alan and Wendy Higginson PC Ron and Katie Robertson PC Bennett Bigelow & Leedom P.S. Christopher Leigh and Ruby D. Wilde Mrs. Holly A. Steussy Mr. and Mrs. Bradley H. Bagshaw The Brown and Hjort Family Columbia Hospitality Inc Mark Davis and Deborah Milter PC Stan and Alta Barer Iva and Lawrence Hirsch John McVickar Robinson and John R. and Paula Blood Family Trust Bill and Jane Lewis Dr. Rainer Storb and Dr. Beverly Torok-Storb Eric Bahna IN Bill and Laura Brown Combined Federal Campaign of North Flight Options Ron and Joan Bayley PC Myrtle T. Holm Estate Elizabeth W. Robinson PC BN Builders Inc. Liberty Mutual Gary and Diane Swofford Bainbridge Foundation Ms. Colleen B. Brown Puget Sound Gabrielle’s Angel Foundation for Sally Skinner Behnke PC* The Horwitz Family Memorial Foundation PC Mr. Tom Robinson and Ms. Carla Murray PC Alice R. Bortnem Trust Carl and Carrie Lovsted TalentWise Julie A. Baldwin Emily A. Brown Combined Federal Campaign of Cancer Research David and Joanna Beitel PC* Mr. Bradley J. Horwitz Satya and Rao Remala Foundation PC* Eric and Shelley Brodersen Brian M. Maloney IN Ms. Myra H. Tanita Mr. Edwin B. Bales Jeffrey and Michelle Brown IN Northeast Florida The Geiger Family Foundation PC* Barbara Berg and Dan Gottschling PC The Hutchinson Family PC* Schwartz Brothers Restaurants Stephen and Jennifer Brooks IN* Mariners Care Dr. and Mrs. E. Donnall Thomas Richard and Joanne Barber IN Gloria S. Browning Combined Federal Campaign Overseas Area George and Margaret McLane Foundation PC Ms. Annikka C. Berridge Mr. Oltion Hyseni Bill and Marlene Semple PC* Mr. Aaron Bueler and Ms. Carolyn True Marketaxess Corporation Paul, Pat and Siri Tift Morgan and Sarah Barbour Karen and Bill Buchan Mrs. Sylvia A. Conaghan Grand Chapter of Washington - Order of the Debbie and Jim Bevier PC Henry and Mary Ann James PC* Harriet and Frank Shrontz PC* Joseph and Mary Bundrant IN* Mattaini Family Foundation Bradley and Danielle Tilden Carrie M. Barham IN Roger and Lynne Buckingham Rachel C. Conway Eastern Star Ms. Joanne D. Blackford PC Mr. and Mrs. J. Michael Johnston PC* Joe Sidorski Fred and Joan Burnstead Jeff and Ethel Maxwell University of Washington Medical Center Gena Barker IN* Melinda A. Buckley Dr. Shannon Corbin and Mary Halls Estate Cathy Boshaw and Doug Edlund PC* David Jones and Maryanne Tagney-Jones PC* Mark and Brenda Simons PC Mrs. Cecelia C. Carr Matt and Carol McIlwain IN* David and Shirley Urdal Donald and Maxine Barnard Troy and Kristin Buckley IN* Mr. Jonathan M. Tingstad IN John J. and Katherine A. Harnish PC Phil and Karla Boshaw Honoring Richard and Caroline Jones - Mr. Benjamin W. Slivka and Richard Carr/Jeanne Meyers; Louise H. and Edward R. Meyer Memorial Trust UW Medicine Health System Barrage Cellars Builders’ Hardware & Supply Company, Inc. Eva S. Corets and Josh Beloff Mr. and Mrs. Troy Hickey IN* Mr. and Mrs. Erik P. Breivik PC* Shelley Hovind PC Mrs. Lisa Wissner-Slivka Franklin Weinberg Fund Jonathan Morrison and Lucy Davies IN* Terry and Lara Vehrs Peter and Jane Barrett Linda and Paul Burg Cornerstone Advisors, Inc. Peter and Peggy Horvitz PC* Betty W. Brinck Estate Rich and Karmann Kaplan PC Doug and Marilyn Southern PC* CBRE Peter and Wendy Mullen VinLozano Imports Inc./Charity Wines Mr. Mathew J. Basta Donna C. Burnstead Mr. and Mrs. Garland D. Cox The Ildhuso Family PC* Shari and Frederick Burns PC* Keith & Mary Kay McCaw Family Foundation PC Tom and Diane St. John PC* City of Seattle Multiple Myeloma Opportunities for Mr. Robert A. Virkelyst Mr. Allen Bauman and Ms. Leslie M. Williams Kristen A. Burrows Mr. and Mrs. John J. Cox Infectious Diseases Society of America Mark and Lisa Caputo IN* Kenneth and Dorothy L. Anderson Family Howard and Cynthia Steinberg PC Clovis Foundation Research & Education Washington State Service Beta Sigma Phi Beards for Breast Cancer Billy and Katie Butler IN Stephanie J. Crabtree IN Jane C. Artz and Frederick J. Artz Fund Carl & Norma Alt Foundation PC Foundation Charlene and Greg Steinhauer PC* Combined Federal Campaign Kitsap-Mason Mr. Dave Myllenbeck David and Marsha Weil John and Molly Beaudoin Ms. Becky Byrd and Mr. Owen Ashurst Derron and Tammi Craft IN The Jean E. Thomson Foundation PC* Carlson Family Foundation PC* Keyes Foundation PC* John and Sherry Stilin PC Counties Han and Shawn Nachtrieb Wells Fargo Bank Rowena M. Beaudry CA, Inc. Matching Gifts Program Mr. and Mrs. David G. Crane King County Employee Charitable Campaign Charles B. See Foundation PC* Jonathan and Pamela Kil IN Cynthia Stroum PC* Combined Federal Campaign of the National Sally and Kit Narodick John and Gerlinde Whetzell Harrell and Virginia Beck CA Technologies Mr. and Mrs. Fenwick J. Crane Klingman Open Charles M. Thomsen Fund King County Combined Federal Campaign The Swanson Family PC Capital Area NC Machinery Co. Ms. Mary H. Wiese Moria and Michael Beck CAC Real Estate Management Co., Inc. Crate & Barrel Mike and Debbie Koss PC* Brad and Judy Chase PC* Reg and Ann Koehler PC* Symetra Financial Cooley’s Anemia Foundation Robert E. and Amy T. Neiman Wight’s Home & Garden Dr. Myrl E. Beck, Jr. Cairncross & Hempelmann PS Cal and Lois Crow Mrs. Frederick Kullman PC Chihuly, Inc. Harry Korrell PC Barbara Thrasher and Rick Koffey PC Dr. Jonathan Cooper and Diane Doles Corrine W. Nelson Stuart and Lucy Williams Stephanie Beck IN Mr. and Mrs. Roger L. Callihan Barbara L. Crowe The Lambeth Family Designated Fund Robert E. Christiansen PC CAPT M. Thomas and Mrs. Gwenann Kroon Bonnie and Jim Towne Copiers Northwest Inc. Patti and Gene Neuberger Mr. and Mrs. Donn H. Wilson Arno Behr and Zelah Kahn Camaloch Lassies Mr. Sylvester T. Cugini Jim and Maureen Lico PC Jeffrey and Janee Christianson PC Sandra L. La Haye PC* Tom and Margo Van Halm PC* Gerald Daily and Janet E. Freeman-Daily John and Billie O’Mack Andrew Benjamin and Shelley Saunders Phyllis J. and William J. Campbell Jeffrey and Lorine Cummings IN Benito and Carmen Lopez PC* Jordan and Katie Corey PC Laura A. Landro and Richard E. Salomon PC Van Sloun Foundation PC* Steve Davis and Bob Evans Mike and Patty Palmer $1,000 - $4,999 Dr. Ronald and Cheryl Berenson Erica and Jose Campos IN Melanie K. Curtice Trish and Peter May Larry and Amy Corey PC Lease Crutcher Lewis Lawrence Votta and Maria Martinez PC Delta Dental Washington Dental Service Christopher P. Parios and Susan Lee Wyant Ms. Susan A. Adams Mr. and Mrs. Paul G. Bergantz Lt. Col. and Mrs. M. Clinton Cannon, RET Diane Hauge Daggatt Hazel E. Miller Trust Tim Cosgrove PC* Lillian Ball Fund Tom and Jeanne Walker PC Hazel Duplissea Estate Mr. Paul S. Pariser Mr. Edward J. Adams-Ralph Peter Berger and Jessica Rossman IN The Capital Group Companies Charitable Mr. J. Mark D’Amato Richard and Kathryn Miyauchi PC Virginia Cosgrove PC Lily Pointe Family Foundation PC Mr. Joseph N. Walter and Ms. Kathy L. Mares PC Lois and Earl Dusenbery T. Keith and Janet Patrick Adobe Matching Gift Program Jeff and Lisa Berkman Foundation Kurt and Leslie Dammeier Muscular Dystrophy Association The CSM Foundation Mark and Nikki Mahan PC* Washington Holdings David and Marsha Ederer The Paul M. Anderson Foundation AEG Erin and Ethan Bernau IN Lyne Caraco Mr. and Mrs. Nelson J. and Ruth L. Darling Nintendo of America Inc. Larry and Vickie Culver David and Nathan Mandelbaum Family PC* Washington State Employee Combined Mark and Carolyn Edson Mrs. Terry Pero AEK Technology, Inc. Yahn Bernier and Beth McCaw IN* Katherine T. Carey Shelly P. and John DaRonche The Old Spaghetti Factory Susan and Tom Dolbert PC David Mann and Ann Thomson Mann PC* Fund Drive David and Sharon Eskenazi Dean and Josephine Petterson Aero Controls, Inc. Bert’s Market’s, Inc. Helga and Vince Carney Judy Dart Prevent Cancer Foundation The Dr. Maxwell Hurston Family John and Liz McAdam PC* Bryan and Pamela Weeks PC Cathryn Fortune and John Shimer Plum Creek Timber Company, Inc. Agenus Inc. Beta Sigma Phi, Tau Master Jeffrey and Kim Carroll Jodi and Tracy Daugherty James and Sherry Raisbeck PC Foundation, Inc. PC Mr. Tim R. McCulloch PC Nancy Weintraub PC Fraternal Order of Eagles, Issaquah Point B, Inc. Aisha Ahmad Al Khinji IN Betz Family Winery Ms. Sara K. Carter Bob and Fran Davidson Paula and Stephen Reynolds PC Jan Dulet PC* MDRT Foundation Mr. and Mrs. James L. Wellinghoff PC Auxiliary #3054 Mrs. Peggy M. Proctor Stephanie R. Alexander Mrs. Rita Bhattacharyya Mr. and Mrs. Richard M. Cashin Davis Wright Tremaine LLP SASCO Mr. and Mrs. E. Julian Eames Pipena Klieros Mercouriadis Marguerite West Estate Mr. Lloyd D. Frink and Ms. Janet Angell Prostate Cancer Foundation Rene Alkoff Andrew Bickar and Lauren Kuhn Gwen E. Ceccanti IN Jane and David R. Davis The Schuler Family Foundation PC* East Bay Community Foundation June E. Miller Doug Williams PC* Gibson Family Foundation RACE Charities, Inc. Allstate Giving Campaign Sue Biggins IN Celebrated Chefs Bertrand and Brooke de Boutray Jim and Jan Sinegal PC* Karl and Carol Ege PC* Mr. Dinarte Morais PC Woldenberg Foundation PC Mr. and Mrs. Burke F. Gibson REB Enterprises, Inc. Marcelo Alonso Gwendolyn R. Billington Stephen and Kim Chaney Lane DeCamp and Holly Smith Peterson Mr. and Mrs. Robert M. Sinskey George E. Fairweather, Jr. Estate Joan Morse and Dean Hachamovitch PC* Lois M. Woodcock and Richard H. Woodcock Stephen and Bridget Griessel Andrew and Christine Reinland IN Alpha Phi Bishop Fleet Foundation Shu-I Chang IN Mike and Candace DeDonker Suskin Foundation PC Chris and Jenny Falk PC Moss Adams LLP Woods & Associates Guy Carpenter & Company, LLC Mrs. Sally Reiquam Alvin Goldfarb Jeweler Stephen and Julie Bishop Thea Chastain Dr. H. Joachim Deeg and Swim Across America Barbara Feasey and Bill Bryant PC* Shan and Lee Mullin PC* The Yeck Family PC Alice Coulon Hanson Relativity Media, LLC Connie and Lee Anderson Mr. Jason Black Steven and Michelle Chattin IN Mrs. Francoise Deeg-Le Gal Mary C. Thorkildsen Estate Fortune Family Foundation PC* Paul and Carol Neiman Melinda Yount PC Jeffrey and Candace Havens Residence Inn by Marriott - Seattle Downtown/ Curt and Ashley Anderson IN Edward and Heather Blahous IN CHCS Consulting, LLC Mr. and Mrs. Philip L. Defliese, Jr. Turner Construction PC* Mr. Robert Frey PC Robert Nelsen and Ellyn Hennecke PC* John and Nancy Zevenbergen PC Mr. Douglas M. Henrikson Lake Union Mrs. Dorothy E. Anderson Mr. and Mrs. Peter C. Boal Dr. and Mrs. Martin A. ‘Mac’ Cheever Valerie Dickover Peter and Shannon van Oppen Dorothy I. Furlong Estate Peter and Sheryl Neupert PC Mr. Hunter S. Ziesing Con Hewitt Dorothy E. Rice Estate Mrs. Karen C. Anderson William A. Bock Cheseapeake Bay Area CFC Mr. Kevin D. Dier Mary Vanderzicht Trust Don and Carol Gagne PC Charles and Eleanor Nolan PC Zillow Mr. and Mrs. Harold W. Hill Robinett Investment Co., LLC Dr. and Mrs. Kenneth N. Anderson, Sr. Mr. Charles J. Bodenstab Lisa Chiang IN* Curt and Anita Dieren & Sons IN Vijay and Sita Vashee PC Mrs. E. Peter Garrett PC North Mason Cancer Crusaders The Zimmerman Family Fund Hitachi Consulting Patrick W. Rose Lisa Anderson IN Sandra A. Boeskov Susan J. Chiavelli Mary S. DiMatteo Bruce and Peggy Wanta PC Michael and Lynn Garvey PC* Robert D. Okada, MD Nicole Hobble Rose-Marie and Jack R. Anderson Foundation Tyler Andrews IN Bon Appetit Management Company Chicago Cubs The Dime Bank

19 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT PRIVATE CONTRIBUTORS FISCAL YEAR 2012

Mr. and Mrs. Gary Dines First American Title Jay R. and Cynthia L. Groepper Barbara J. Howell Mr. Robert E. Kilian Diana Lynn IN Mr. and Mrs. Ronald Moller Pepsi Bottling Company Rockwell Collins Mr. Richard P. Simmons Ms. Mary E. Dingledy Bill and Carolyn Fischer Tom and Tina Grohman Ron and Darlene Howell Jerry and Marcia Kindinger The M&T Charitable Foundation Robert P. and Lucille L. Mone The Peras Mr. and Mrs. G. Saxon Rodgers The Skier Foundation DiPietro Family Foundation Eulalie M. Fisher Mr. and Mrs. John Gunning Brock and Dottie Hudson King Broadcasting Company Dennis and Vannessa Ma IN Morningside Foundation Dan and Stephanie Peters Mr. Jeffrey N. Roehm Skills Incorporated Satnam Doad IN K. Joan Fisher Mr. and Mrs. Nils M. Gunther Hong B. Huey and Mary Huey Mr. Andrew L. King Mr. and Mrs. Dean F. Maggs Mr. and Mrs. Larry A. Morris Dale W. ‘Corkey’ Petersen Mr. and Mrs. Dennis W. Rohling The Skolnick Foundation Kimberly Dodd Phelps and Christel Fisher Susanne and Scott Guthrie IN* Trevor and Donabelle Huffmaster IN Lynette A. Klein Jermaine E. Magnuson Mr. Robert M. Moser Donald B. Peterson and Cecilia M. Giachelli Ms. Pamela L. Rolfe John and Susan Skovron Dodge & Cox Jon and Laura Fleming Mr. and Mrs. Alan W. Haight Mr. Tom Hull Mr. and Mrs. Lance Kliewer Randy and Retta Main Bud Mount Janet and Eric Peterson Carol S. Roll Jennifer J. Slifka IN Domaine Serene John and Mary Folger Jean D. Hall Olivier and Catherine Humbert IN* Dr. John Klippert Mr. and Mrs. Edward J. Malley Marianne G. Mowat IN Paul M. Peterson IN Carol Roll and Joe Mills Dorothy P. Sloan Terrence J. Donahue Foss Maritime Company Maureen Halligan and Frank Brennan C. Dan and Irene W. Hunter Jeff and Michelle Knoll IN Kostas and Kristi Mallios Mr. Robert G. Mower, Jr. Mr. and Mrs. Randal L. Peterson James and Jane Roll Mr. and Mrs. Donald C. Smaltz Russell and Marion Dorer IN* Chuck and Evelyn Foster Ron and Candace Hallissey Kyle Hutchins IN Cynthia R. Koehler Fred and Ruth Maloney Mahlon M. Moyers Susan E. Peterson Mr. and Mrs. Kenyon B. Roll Jenna L. Smith The Douglass Family Foundation Foundry Vineyards Sajva Halverson Bradley and Kimberly Hutchinson Nora Korg Jason J. Maloney IN Ulrich Mueller and Diana Ensenat IN* Roger and Cynthia Petrie Ms. Joan Rolph Mr. and Mrs. Robert J. Smith Mr. and Mrs. Bruce D. Douglass Dr. Henry E. Fourcade and Anne M. Hamilton John and Bonnie Hutchinson KPMG LLP Steve and Janice Malos Mark K. Mullane Brad and Hope Pettinger Mr. and Mrs. Page Roos Mrs. Sandra L. C. Smith Tom and Kay Dowd Mrs. Myrna P. Fourcade Kathryn Haniuk Scott and Amy Hutchinson IN* Mark and Kathy Kralj Corwin Malott Craig and Marie Mundie Bill and Kathy Pettit Stephen and Elizabeth Rosenman Richard and Judith Smooke Mike and Roberta Doyle Fraternal Order of Eagles #1722, Dave and Sandy Hanower Dr. and Mrs. Stuart R. Hutchinson Mr. Michael A. Kramer Helen and David Mandley Ms. Cynthia M. Murray Phinney Ridge Cabinet Company Michael B. Rubin Cherry and George Snelling IN* Traci L. Drake and Ann Torres IN Renton Auxiliary John M. Hanson and Sharon A. Hanson Shirley M. Hvalsoe Michelle R. Krumland IN Marcus Whitman Hotel & Conference Center Mr. and Mrs. Howard L. Murray Dan and Joanna Pinick Allan and Barbara Rumpf Snohomish County Superior Court Michael and Jennifer Dubinsky Frazier Family Foundation IN Jeff Hardie and Laurie Saito IN* Mr. and Mrs. William B. Hyde Ms. Thanaporn M. Kulthol Mr. Paul Marczynski Kathleen A. Nacey Jeff and Janey Pinneo Scott and Susan Rusch Sol and Sadie Esfeld Memorial Fund of the Collette L. Duck IN Mr. G. Thomas Frederick Ms. Gayle R. Hardt IBM Employee Services Center Dr. and Mrs. Thomas Kun and Rita Kun Master Shon Tae Kwon Do Center Dr. Keyvan and Parvin Naficy Michael and Heidi Plaster IN* Russell Matching Gifts Program Jewish Federation of Greater Seattle Dunham Cellars Mr. and Mrs. Frederick K. Freeman, Jr. Dr. Brian and Carolyn Harris iFly Seattle Richard Kyle and Kara Matthew IN* Cathy Mathews National High Five Project Carl and Donna Platou Mr. and Mrs. Anthony A. Russo Mr. Robert Sollesvik Mr. and Mrs. Richard A. Dunn, Jr. Mr. Rodney Fujita Mr. and Mrs. Joe W. Harris IMG Lachini Vineyards Matthew Blend Fund NBBJ Plum Creek Foundation Mr. and Mrs. Wilbur E. Rutherford Spectrum Specialty Builders Inc Dunphy McLean, Inc. Functional Health Chiropractic Kathryn Harris Industrial Credit Union Hannele Laine IN Ryan and Sara Maxwell IN* Ms. Carol R. Nelson Cynthia and Ryan Poole IN Jeannine and Tom Ryan Mr. Michael R. Spilker Eric Durban John Gadon Michael F.O. and Alison Harris ING Direct Matching Gifts Mr. Walter W. Laity Peter J. May IN Marian L. Neuhouser, PhD Port of Seattle Andrew Ryder IN Amy Spraggins IN William and Jane Durch Phil and Lisa Gafken IN Patricia Harris J.CREW Moe Lance Carol Mayo Mr. and Mrs. Dave Neumayer Bradford and Sandra Porter Mrs. Susan Sabsowitz Ron and Mary St. Martin Jason and Leanne Durfee IN Ms. Linda L. Gainer Peter Harris Mr. and Mrs. Arthur D. Jackson, Jr. Carol J. Landis Mr. and Mrs. Mario Mazzola Todd and Marci Nicholson IN Darin Postma IN Irada Sadykhova Mr. Robert W. Stafford, Jr. Todd and Virginia Dutkin IN Mr. and Mrs. H. Graham Gaiser Kevin and Bobbi Harrison IN Hanan Jacoby and Benu Bidani Mr. and Mrs. Aram N. Langhans Tod and Christa McBryan IN* Mr. H.C. Buck Niehoff Caleb and Ann Powell IN Mr. and Mrs. Gerald M. Salkowski Staggs Coins, Baseball Cards and Collectibles Michael and Diane Dwyer J. James and Margel S. Gallagher Peder and Theodora Haslestad Jeremy and Jacquelyn Jaech Lantz Cellars Dr. and Mrs. Marshall Edward McCabe Mr. and Mrs. Wayne E. Niemuth Mrs. Vicky L. Prahin San Diego County Combined Federal Campaign The Standard Employee Giving Campaign Pete and Phyllis Dybsand Juanita M. Garrison Mr. Michael H. Hassenger Jameson Babbitt Stites & Lombard, P.L.L.C. Mr. Dave N. Larson Diana McCasey Mark and Sue Nikiel Kathleen Walker Pratt Justine and Rob Sands IN Employee Donations Mr. and Mrs. Hugh E. Eddy GE Foundation P. M. Hathaway Pierre and Christine Jammes Richard S. Larson III Bruce and Jolene McCaw Noble Wines Ltd. Precor, Inc. Saturna Capital Mr. and Mrs. Robert Steeg Mr. and Mrs. Charles Ede Ken and Lisa Geisen Peter and Pat Haug La Fon Jantz Mr. John W. Lash McCrea Cellars Ilse Nordmann and Jorn Nordmann Premera Blue Cross Mr. and Mrs. Joseph S. Saxon, Jr. Monica L. Stein Edith and David Altman Foundation Max Gellert Jason Hazlett IN David and Elisabeth Jenni Eva Lauve Mr. and Mrs. Richard B. McCune Novo Fogo Presbyterian Retirement Communities Mrs. Janet M. Schlameus Mr. Seth Steinberg and Ms. Candace Kalish Michael and Anna Edmonds IN Mark and Deborah Gentzen IN* John N. Healy IN Mr. and Mrs. Jensen Richard and Rosemary Law Matt and Wendy McCutchen Beatrice H. Nowogroski Northwest Kyle Schnider Allyn Stellmacher and Terry Samilson Julie Edsforth and Jabe Blumenthal Jane Gerhardt Heart of Alabama Combined Federal Campaign Lois Jepson Lawrence and Sylvia Wong Foundation, Inc. McDowell Family Charles Nylund Elizabeth Prescott and Daniel Stetson IN* Schoenfeld-Gardner Foundation The Stenmoe Agency Jeffrey and Karen Edwards IN Mrs. Angie Gianelli Mr. and Mrs. Jack Heath Ms. Jean Jessen Kari Leal and Sandra Matteson Joan Ellen McInerney, MD FACEP Donald and Kristi Oates IN Geoff Price and Lisa Ladmer-Price IN Daniel R. Schroeder IN Ms. Dawn Stephens and Mr. Patrick Mendiuk David P. Eich IN Dr. Kenneth E. Gibson Jane Margaret Hedberg Allen and Carleigh Johnson IN* Mr. and Mrs. Robert D. Leggett McKinstry Lee and Deborah Oatey PrivatePortfolio Group, LLC Casey and Allison Schuchart IN Robert Gary Stevens Eirschele Consulting Services PLLC Scott K. Gibson Hedges Family Estate Arthur N. F. Johnson Trust Daniel A. Lelewski IN Mrs. Aurelie McKinstry Mr. and Mrs. Michael J. O’Brien Mr. Brad Proctor Patrick and Dianne Schultheis Stewart Title Steve Eirschele and Erin Guthrie Mr. and Mrs. Peter J. Giffin Mr. and Mrs. Severt S. Hegland, Jr. Brent and Catherine Johnson IN* Leonetti Cellar Doug and Ruth McKnight Mr. and Mrs. Mark F. O’Donnell Puget Sound Family Physicians, Schwabe Williamson & Wyatt, P.C. Dr. and Mrs. Marc Stewart Allan and Peggy Elenbaas Marybeth Gill Jeffrey and Shelly Heier IN* Ms. Christine K. Johnson Mr. Ricky L. Leong Nancy McLaren IN Tim Oerting IN* Edmonds Family Medicine Ann and Richard Scott Mr. and Mrs. Michael Stewart Mr. and Mrs. Steven L. Elfman Shelley and Lee Gill Todd and Stephanie Henderson IN* David and Christy Johnson IN Mr. and Mrs. John Lester Tim and Teri McLean Mr. Daniel Ogg Queen Anne Frame Seabrook Land Company Mr. and Mrs. R. B. Stewart Jerry E. and Julianne C. Elkington Mr. Thomas W. Gille Mr. John Hennessy Elaine H. Johnson Phyllis Leventhal Mr. and Mrs. William McNabb Carol R. Ohlmacher Robert and Victoria Quiles IN* Jeff Sears IN John and Patricia Stockamp IN* John and Farida Elliott Nancy R. Giuliano Mr. and Mrs. Richard C. Henriques Glenn Johnson and Michael Melancon David and Dana Lewis Mark A. and Marna L. McNaughton Mr. Richard Olin David and Hillary Quinn Seattle Bookings Dr. Barry L. and Amy B. Stoddard Dr. and Mrs. Harley Ellman Mr. Charles W. Glass Michael F. and Carol S. Herbert Jeffrey and Paige Johnson Frank and Marianne Liebermann Justin Meaney IN* Larry Olli and Andrea Ward Michael and Kristine Quinn Seattle Genetics, Inc. Mr. Charles L. Stoddard Mr. and Mrs. Jeffrey B. Ellman, Esq. Glen Carbonic Gas Co. Bob and Pat Herbold Mr. Jonathon W. Johnson Jerrold Liebermann and Linda J. Harris Medco Health Employee Giving Campaign Ms. Gretchen Olsen-Jacobsen R.D. Mushen & Associates Seattle Sounders FC Stoel Rives LLP Lynda Emel William and Kristen Glenn IN Mr. and Mrs. Thomas F. Herche Preston Johnson and Vicki Martin Clark and Lori Lindsay IN Judy and David Melody Miss Elvi M. Olsson Gustav F. and Claire T. Raaum Jeffrey and Jenny Sebenik IN Stratos Product Development Equifax Foundation Val and Ivene Goemaere Mr. and Mrs. James B. Herd Mr. Richard A. Johnson Alexander C. Lindsey and Lynn M. Manley Mr. Brian Merisko Olympia Street Rod Association Kenneth G. Ragland Mr. Jack Seeley Stubbeman Family Foundation Angela Estey IN Mr. Richard M. Gold John and Diane Herfort Johnstone Supply of Denver Michael Linenberger, M.D. Merrill Lynch Trust Company Mr. and Mrs. Richard J. Omata Mrs. Ann Ramsay-Jenkins Mr. and Mrs. Ralph M. Seifert Stephen and Sheila Styrchak IN Jennifer Evans and Darin Kudrna IN* Frederick M. Goldberg and Carolyn Lakewold Mr. and Ms. Joaquin M. Hernandez Andrea Jones IN* Ms. M. Suzanne Linford Mrs. Charlotte M. Merritt Sheila and Mel O’Neal James Ramsey IN Mr. John S. Selby Ms. Edith S. Sullivan John Evans IN Goldman Sachs & Co. Matching Gifts Program Ms. Anne T. Herrick Jessica Jones IN Lister Chain and Forge Inc Lawrence and Bernice Meurk Mr. Jack W. Oppelt Linda Ranz IN Mrs. Ann M. Selland Suncadia Grant W. Eve, CPA IN Kelley Goldmanis IN Richard and Marilyn Herzberg Rich and Aimee Jones David A. Little and Michelle A. Gray Mrs. Cheryl S. Meyer Mrs. Henry L. Osterman Allison Reed IN Sellen Construction Company Kyle and Emi Suzuki IN Mr. Joseph P. Eve and Sara and Gideon Goldstein Bill and Emily Heston JP Morgan Chase & Co Employee Giving Richard E. Little Dmitriy Meyerzon IN Jesse Ottele IN Paul and Charlotte Reed The Seneca Real Estate Group, Inc. Michael Swafford IN* Mrs. Melanie Vankoten-Eve Google Matching Gift Program Mr. and Mrs. David F. Hiestand Campaign Don and JoEllen Loeb Michael Adair Family Foundation Dr. Robert W. Overell and Mrs. Sally Overell The Regence Employee Giving Campaign Mr. Charles K. Sergis II Gerald and Elizabeth Swan Expeditors International of Washington, Inc. Douglas Gordon IN Larry and Marcia Hilberg Juniper Ridge RV Homeowners’ Association Matt and Elisha Logue IN* Joseph Miglino Robert B. Overhus Regents House Ltd Mr. and Mrs. Ronald C. Seubert Dr. and Mrs. Robert J. Swanberg Judith D. Faas GPMCH Foundation Steven and Taeko Hill JustGive.org Mr. and Mrs. David B. Lomet Mill Creek Sports Cards James T. ‘Jess’ Owen Mr. and Mrs. Gary M. Reilly Douglas Sevier IN Ted and Dominique Sweeney Adam N. Fain Dennis and Karen Grace Brent and Dulcy Hixson IN James and Angela Kahler IN Mrs. Mari London and Mark Popich IN Miller Nash LLP P & A Pellarin Associates, Inc. Srilata D. Remala IN Doug and Lisa Shaeffer Mr. Jay R. Sybert Ms. Limei Fan Mr. Donald G. Graham, Jr. Brandon Hoff IN Jeanne Kanach The Mark A. Long Family Barbara A. Miller and Anne E. Nicoll Mr. James D. Paddleford and Kim and Gwen Reynhoudt Shane and Katie Dir Charitable Fund IN Mr. Daniel D. Syrdal Norris and Alice Faringer Roger and Jennifer Grambihler IN* Gregory and Joelle Hoff Michael Kaplan Christi Ball Loso IN* Mr. and Mrs. Dale E. Miller, Jr. Mr. Dent W. Davidson Maurice Rice IN Mark and Susan Shapiro IN* Sysco Central Pennsylvania, LLC Ms. Sophia Faskianos and Mr. Stephen Capus Mr. David K. Grant Dayton D. Hoffman IN Ms. Heidi Kass Jeffrey and Jennifer Lounsberry IN John and Joyce Miller Palisade Restaurant Terry and Ben Richardson IN Shaughnessy Real Estate Limited IN Monte and Nan Szendre Gary and Mary Fedorochko IN* Mr. and Mrs. Lee M. Grayson, Esq. Janet Hoffman IN Kauffman Family Foundation Mr. and Mrs. Keith Loveless Mr. and Mrs. John F. Miller, Jr. Pamela B. Katten Memorial Leukemia Mr. Thomas S. Ricketts Bridget Shaw IN TalkingRain Beverage Co Ms. Hilary A. Feier and Mr. Frank Rossi Mr. and Mrs. Cameron W. Green Scott and Debbie Holbrook Jim Kaufmann and Mary Thrasher Stephen E. Lovell Michael and Lisa Miller IN Research Foundation Mr. and Mrs. Charles W. Riley, Jr. Mr. and Mrs. Frank X. Shaw Mr. and Mrs. Stephen G. Tandy Mr. and Mrs. Richard S. and Harriet K. Fein Greenbaum Home Furnishings Mr. Mark S. Holden Mr. and Mrs. Thomas W. Kearns, Jr. Sandra Low and Christopher Flynn IN* Richard B. Miller II IN Papé Material Handling Mrs. Jeanette B. Ristau Mr. Monty Sheldon Mr. and Mrs. Lawrence E. Taylor Jay Feinberg IN David Greenberg Scott and Joanna Holden IN* Mr. and Mrs. Daniel J. Kennedy Mr. and Mrs. Russell D. Lowell Mr. and Mrs. Roger N. Miller Steven W. Parmelee RJ Smith & Associates Shirley and Jim Shenk Team Photogenic Dr. and Mrs. Matthew L. Fero Greene Wealth Management LLC Ms. Doris W. Holmes Kennedy/Jenks Consultants, Inc. Claudia R. Luebbers Tammy Miller Mr. David Passeau RMG Associates LLC Mr. and Mrs. Jonathan Sheppard Dr. and Mrs. James N. Thomas Brett J. Ferullo IN Dr. Benjamin E. Greer and Ms. Sheree A. Miller Robert and Ruth Holmes Mr. and Mrs. Robert J. Kenney, Jr. Karen Luk IN Milliman Inc. Mark and Jennifer Pawlosky IN* David W. Robinett IN Mr. Mike D. Shinn Ms. M. Jane Thomas Kristen Finholm IN Matthew S. Gregory Mr. and Mrs. Scott A. Hopper Olive Kerry Trust Luly Yang Couture Nikki and Chris Milonas IN Franci E. Pease Mr. and Mrs. Henry M. Robinett Kurt and Kylee Shintaffer IN* Nate and Jean Thomas Scott and Amy Finholm IN* Mr. Skip Gribble Gregory Hotz IN* Kibble & Prentice Luther and Zita Templeman Foundation Rick and Joyce Miner Karen Pease & Bob Barlow Bruce and Diane Robinson The Sign of the Orz Ronald and Mary Thomas Firesteed Wines Mrs. Leonie B. Griswold Harry M. Howarth Mary Jo Kilian David and Deborah Lycette Ben Minicucci and Barbra Rigelhof IN Mr. and Mrs. Clark M. Pennington Craig and Jessica Robinson IN* Scott E. Silver Mr. Teddy R. Thomas SCIENCE GIVES BACK. 21 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT PRIVATE CONTRIBUTORS FISCAL YEAR 2012

Dick and Ruth Thomassen Darren and Leann Watts IN* Legacy Partners in Research Ms. Barbara Chester John and Roberta Hayes Elinor K. Menter Mary L. Sanderson-Schinman Legacy Partners in Research members include Mrs. Barbara Thrasher $10,000 - $24,999 Mrs. Barbara H. Thomson Mr. James C. Watts Legacy Partners in Research are individuals Susan L. Christiansen Hal and Jerry Haynes Pipena Klieros Mercouriadis Colleen Swift Schafer 147 anonymous benefactors. Bonnie and Jim Towne The 5th Avenue Theatre Carlyle P. Thorsen IN Mr. Todd E. Weaver who support the Hutchinson Center through Gus Churchill Dr. Frederick and Margaret Hazeltine June E. Miller Patricia L. Schaumberg James and Roberta Weymouth Chin-Ley/Reche Associates Carol B. Tidyman Eric and Catherine Wedge IN a bequest in their will, life income gift, life Emanuel and Susan Cohen Patricia and Robert D. Heffernan, Jr. Robert Miller and Marlys Owen-Jones Brent and Susan Schlosstein Inner Circle Edmonds School District No. 15 Dr. and Mrs. Wayne J. Timberlake Michael and Paula Weintraub insurance, retirement asset or other planned Mr. Milton M. Cohen Mr. and Mrs. Severt S. Hegland, Jr. Verna L. Miller Rosalyn H. Schuknecht The Inner Circle is comprised of current and Inner Circle members include eight Jacobs Johnson Foundation Ms. Bonnie Timm and Mr. Gregory A. McFadden H. Janet Weiss gifts. As Legacy Partners in Research, they Bob and Sylvia Cook Ms. Jean S. Heidt Mrs. Anne A. Moldrem Robert E. Schultz former Hutchinson Center faculty, staff and anonymous benefactors. Liberty Mutual Mr. and Mrs. Christopher J. Tingman Wells Fargo Community Support Campaign create a legacy for themselves and their Norma M. Corbin Mr. and Mrs. David C. Henderson Mr. and Mrs. James A. Morrison Dorothy L. Shattuck their spouses; past and present members of Perkins Coie LLP Eric and Carmel Tirschwell IN Wells Fargo Insurance Services families and play a pivotal role in benefiting Fred Corrado Ralph and Gail Hendrickson Joan and Michael Morse Pam and Geoff Sheridan the Board of Trustees, Board of Ambassadors Committees, Councils and Guilds Sterling Realty Organization Perry Tirschwell Mr. Richard L. Wells future generations. Mr. Martin J. Costello Gregory and Anne-Marie Henry Betty and Mahlon Moyers Pearl L. Shernoff and Senior Council and their spouses; as well Fred Hutchinson Cancer Research Center’s Andrew and Shana Tischaefer IN Renee and Paul Wesberry IN* Mary Pat Cotty Conrad W. Hewitt Judy Mukai Mr. C. Larry Shull as past members of the former Foundation committees, councils, and guilds are comprised $5,000 - $9,999 The Titus Will Families Foundation Mr. Scott Wessel-Estes Charles M. Ackerman and Fred M. Cox Larry and Marcia Hilberg David and Pam Mushen Joe Sidorski Board of Directors and their spouses. It of volunteers throughout the Puget Sound area Carl and Renée Behnke The Todd Organization of Seattle-Portland, LLC Westhill Inc. Barbara Clanton Ackerman Mr. and Mrs. Fenwick J. Crane Mrs. K.L. Hillard Mr. and Mrs. Al Neelley Jean Simmons recognizes those who support the Center who come together to raise awareness of the Costigan Integrated Mr. James Toepel The Westin Mission Hills Resort Mr. Donald D. Ackley Roger and Gloria Crouch Michael and Rosemarie Hitt Miss Elsa Nordin Ms. Annette Siversen through a bequest in their will, life income Center’s mission. Through various activities FBI Agents Association Gregory and Marilyn Tompkins Westlake and Harrison, Inc. Arleta Rae Allen Lamont Crumley and D. Dianne Wilson-Crumley Charlene P. Holt, MD Mrs. Ella Nuckolls Mr. Eugene G. Sivertson gift, life insurance, retirement asset or other and events, these committed volunteers raise Employees Community Fund of The Boeing Ms. Theresa B. Torseth James and Roberta Weymouth Jim S. and June M. Allen Mrs. Leah Currie Vivian and Les Houle Ken and Julie O’Brien Mrs. Phyllis H. Smith planned gifts. and provide critical funds for Center research Company Touchstone Corporation Kristen Wellinghoff Wheeler and Ms. Chelea Alwine Daryl Drew Charitable Foundation Mr. and Mrs. James W. Howard Milton O. and Carole A. Olson Samuel E. and J. Michelle Smith and provide services for patients and their Gary E. Milgard Family Foundation Thien Minh Tran IN Christopher Wheeler IN Jan A. Amen Joan A. De Bruin Barbara Howell Miss Elvi M. Olsson Joseph T. Smudin Steven J. and Lisa M. Anderson family members. Mr. and Mrs. Robert L. Gerth Barbara Trask and Ger van den Engh Frances Whetten Alex and Helen Andersen Mr. and Mrs. Henry W. and Frances C. Decker Mr. and Mrs. George C. Hudspeth Sheila and Mel O’Neal Mr. Frank W. Soderling Robert M. Arnold LeRoss Family Foundation Treasure Island Family Fun Run/Walk Denise Whitaker and Terron Lindholme Dorothy E. Anderson Lou Denney Mr. and Mrs. Paul S. Hunter Everett and Dorothy O’Neill Gregory P. Sokolowski Rich and Leslie Begert Brosio-Hamasaki Stein Guild Low Pressure Promotions, LLC Ian and Leslie Tubbs Whitcomb Insurance Agency Stuart L. and Karen C. Anderson Leslie and Deborah Disch Floyd and Barbara Hutton Mrs. Jean B. O’Neill Herba Irene Solstad Carl and Renée Behnke Climb to Fight Breast Cancer Committee Messenger Signs Gary and Amanda Tucci Stacia L. White IN Bill and Ruth Anderson Chris and Viki Parrott Dragich Mr. and Mrs. James G. Hutton Stanford E. Opdyke Mary and Steve Solum Sally Skinner Behnke Friends of the Hutch Mr. and Mrs. John H. Mills Ms. Jean Q. Tuesday Mrs. Michelle G. Whitten Ms. Victoria Andrews Wayne D. and Susan E. DuPont Dr. and Mrs. Gordon L. Imlay Arthur and Viola Oquist Sara Somers Brian R. and Shelley J. Buck Grace Heffernan Arnold Guild Morgan Stanley Smith Barney Global Impact Jim and Pat Twisselman Alinda and James Wikert Ardean A. Anvik Lois and Earl Dusenbery David and Gigi Jack Robert B. Overhus Mrs. Kathleen P. Spading William W. and Kathy Lynn Christoffersen Hutch Award Luncheon Planning Committee Funding Trust, Inc Vivien Tye Charles and Linda Williams Robert and Clodagh Ash Mr. James P. Dye Douglas L. Jacobs Clyde W. Owen Josephine and Stephen Spear Mr. and Mrs. John D. Eastham Hutch Holiday Gala Board of Directors Bud Mount Luis and Colette Ulloa IN* Mr. Tony J. Williams Alan and C.J. Ashton Peter S. and Sandra W. Dyer Dorothy Doyle Johnson Stanley Ozbolt James Speckbrock Karl and Carol Ege IN for the Hutch Committee Rona Consulting Group Mr. Jerry E. Ulmer Stacy A. Wilson IN Dr. Elizabeth Atwood Mr. and Mrs. Robert L. Ecker Mr. Douglas B. Johnson Mr. James D. Paddleford and Jenny Rebecca St. Martin Robert N. and Ingrid Lahti Eisenman Innovators Network Council United Way of King County Umpqua Bank Associate Giving Campaign Mr. Daniel P. Wimsatt N. Faye Bachmeier Demerise Eddy James A. and Holly F. Johnson Mr. Dent W. Davidson Mrs. Caren A. Staley Barbara Feasey and Bill Bryant Institute for Prostate Cancer Research Union Bank Employee Workplace Campaign John and Beth Wojick M. EuGene Barnes and Beverly Ann Barnes Jerry L. and A. Christine Edwards Robert P. Johnston Mr. and Mrs. Jack G. Parks Evelyn Casey Steen Ms. Linda L. Gainer Community Leaders Council $1,000 - $4,999 United Way of Greater Los Angeles Jeff and Maria Wolcott IN* Patricia M. Bartlett Alvin and Maija Eerkes Thomas M. Jones and Judith A. Edwards T. Keith and Janet Patrick Mrs. Idalene Strang Janice A. and Robert L. Gerth Jacob Green Charity Golf Classic Committee Alderbrook Ladies Golf Club First Mates United Way of the Quad Cities Area Corinne Woodward IN Thomas P. and I. Georgina Bayley Mr. and Mrs. Jeffrey B. Ellman, Esq. Abraham and Geetha Joseph Grafton Pauls and LaVonne Pauls Robert J. and Kathleen A. Swanberg Kenneth and Beryl Goodchild Magnolia Guild Allflight Corporation University Mechanical Contractors, Inc. Conrad Wouters and Glenna Olson Ms. Diana Beckers Cecil David Enman and Norma J. Enman Elaine N. Kaald Harry and Katherine Pearce Janet Swanson Dr. William Grady and Dr. Karen Tsuchiya Margaret E. Martindale Guild Association of Community Cancer Centers US Bank National Association Craig and Joan Wrench Barbara M. Bedayan Wayne and Katherine Eshelman Ellen Kam Kristian Pearson Connie Taylor Sheri Ray Greaves Olympia Guild Auburn School District #408 Mr. and Mrs. Mitchel D. Usibelli Virginia Wright Rod Belcher Thomas G. and Kay Nozaki Ewing Mal and June Karfstedt Frederick and Elizabeth Pedersen Ken and Judy Thomas Marcia and Glenn Harrington Pete Gross House Council Mr. Robb Bakemeier and Va Piano Vineyards Ann P. Wyckoff Mr. Will H. Bennett June Faralla Ms. Heidi Kass Mary R. Pelan Dick and Ruth Thomassen Debra and Chuck Holland Premier Chefs Dinner Advisory Board Mrs. Karen Rosengren Valley Electric Mrs. Jean T. Wyckoff Marc A. Berger Colin Faulkner Ms. Deborah Kaufman Daniel J. Peters Mr. and Mrs. Charles M. and Marjorie J. Thorne Shelley Kuni Hovind President’s Affiliates Council Bank of America Julie S. Vallin Yakima Valley Old Peoples’ Riding Club Mrs. Sidonia Berglund Mr. Richard Faulstich Brant A. Keeney George and Cynthia Pierce Olive Tice Nancy Greenwood Vehrs and Jeff Vehrs Partners for Survivorship Council Mr. and Mrs. Steve W. Berman Dr. Anthony Van Ho IN Chris Yarrow Yahn Bernier and Beth McCaw John and Rosemary Fedorochko Frederick and Julianne Klippert Julia B. Poduch Mr. and Mrs. Michael J. Toennessen Deborah E. Kirsner Bill & Melinda Gates Foundation Anthony and Patricia Van Ruiten Jay and Leslie Young Mr. and Mrs. Harry C. Berryman Mary Jane Fee Nora Korg Bradford and Sandra Porter Frances Welguisz Tomasko Lynette A. Klein Seattle Cancer Care Alliance Mr. Bill Blackburn Ms. Bonnie J. Van Sickle Mr. Richard S. Zahniser Henry A. and Marjorie M. Bickel Clifford H. Fiscus Mr. and Mrs. Gary A. Krape Deirdre and Dickson Preston Mr. and Mrs. David T. Troxel Reginald S. Koehler III Seattle Cancer Care Alliance (SCCA) unites the Bluebills Heritage Chapter Ms. Suzanne E. Vaughan David A. Zapolsky Sandra Kailes Biller Anton M. and Barbara C. Fleischman Mr. and Mrs. David Kremers Mr. Ross Purintun Karl R. and Marcile H. Turner Judy Kornell world-class treatment and research activities Ms. Linda K. Bonet Nancy Greenwood Vehrs and Jeff Vehrs Stephen W. Zaruby and Laura Pierce The Billson, Rita and Ivan Jane B. Folkrod Donna L. Kyle Mr. and Mrs. Robert and Teresa Quigley Mr. and Mrs. Robert E. Vallat Rose Kowalski of Fred Hutchinson Cancer Research Center, Breast Cancer Emergency Fund Mr. and Mrs. James E. Veitengruber ZICO Beverages LLC Ellen O. Blackstone Bob and Lanie Franza Larry and Linda LaBolle Gustav and Claire T. Raaum Jean Baur Viereck Ms. Karen E. Lane UW Medicine and Seattle Children’s. In fiscal Carillon Point Account Jean B. Viereck and Robert S. Leventhal Sandra A. Boeskov Richard and Linda Frasch Mr. William M. and Dr. Geraldine K. Landis Sherry Y. Rae Mr. Jerry Warfield Jerrold D. Liebermann and Linda J. Harris year 2012, 2,118 donors contributed more Dr. Shannon Corbin and George and Laura Jane Viverette Individuals and corporations who contribute Barbara A. Bonamy Bill and Deryn Fulton Al and Laura Laney Mrs. Della L. Ramsden Jim and Diane Watson David A. Little and Michelle A. Gray than $3 million to SCCA to support efforts Mr. Jonathan M. Tingstad Mrs. Carol Lee Von Gortler-Baker $10,000 or more annually are members of the Christine Borgen Larry Gahlhoff Mr. and Mrs. Gus Lange Weldin and Jo Ann Read Barbara H. Weaver Jeffrey and Ethel Maxwell to provide premier, patient-focused care and Custom Craft LLC Cecilia M. Votta IN Center’s President’s Circle and are noted with Robert and Sheila Bosanko Ross M. Galvin, M.D. and Patricia G. Galvin Lolita Lanning Thomas L. Reid Steve and Dana Weiner Rachelle A. McCallum access to groundbreaking clinical research to Mr. and Mrs. Donald A. Dick, Jr. Brian and Susan Vowinkel IN a “PC” below. Individuals age 45 and under Arthur R. and Bernice J. Bowers Ken and Lisa Geisen Gloria L. Larkin Mrs. Sally Reiquam Lewis G. Weiss Patricia McCowan patients from around the world. Donna’s Tournament W New York contributing between $1,000 - 9,999 are mem- Sandra Brentlinger Jane Gerhardt E. Margaret Lawrence Bruce and Karen Richards Sandra E. Weiss Robert D. and Patricia A. McDonald Mr. and Mrs. Stanley Edmond W Washington D.C. bers of the Innovators Network and are noted Christine L. and Michael L. Brinton Roman J. Gerstner and Evelyn R. Gerstner Roy and Vel Leonard Douglass and Lea Richter James P. Welch Neil and Nancy McReynolds $1,000,000 and up Mr. Robert F. Elliott and Ms. Margaret E. Taylor Daniel R. and Kim M. Wade IN with an “IN” below. PC and IN members make Mary and Geary Britton-Simmons James D. and Paula J. Gillmore Marjorie J. Levar Mr. and Mrs. Joe A. Riedel, Jr. Catherine and Steven Wells Karen and Jamie Moyer Norcliffe Foundation Dr. Sherman S. Ely, D.D.S. Mr. and Mrs. J. H. Waechter outright gifts supporting high priority projects Elmore G. and Dorcas Brolin Eileen Goebel Mr. and Mrs. Stephen H. Lindquist William A. Ritter Nick and Carol Westlund - Supporting Shan and Lee Mullin Expert Drywall, Inc. Susanne Wagner-Fischer IN that accelerate the pace of promising research. Steve and Gayle Burditt Mr. and Mrs. Wayne C. Gott Ralph and Lynda Lipe Mrs. Margaret Robarge Organization Han and Shawn Nachtrieb $100,000 - $249,999 Ms. Janice L. Ferguson Wagstaff, Inc. Mrs. Jennie K. Burwell Ron and Cathy Grant Lynn Lippert and Sal Jepson William A. (Bill) Roberge Richard and Annette Whitaker Paul and Carol Neiman AEG Live Fraternal Order of Eagles Prairie Aerie #4144 Ryan P. Waldenberg IN Key Mr. and Mrs. Jack and Patty Bush John and Ann Guerin Nick V. Louis Ray A. Robinson Mrs. Edward Whitley Martin and Vicki Nelson The Madhouse Project Freestone Capital Management Charitable Wallenpaupack OFPX, LLC PC*= President’s Circle Charter Member Stephen D. Cameron Jack and Dorothy Guinn Stephanie D. Mapelli Marilyn H. Rogers Michael and Marie Legaz Whitley Dr. Gilbert S. Omenn and Martha A. Darling The Safeway Foundation Foundation WAM, LLC PC = President’s Circle Clint and Ruth Cannon Sharla and Don Hamilton Mr. and Mrs. Robert J. Margulis Claudia Rollins William and Susanna Wiegant John and Deanna Oppenheimer Swim Across America Ms. Leslie Freund Sheri L. Ward IN* = Innovators Network Charter Member Phillip and Violette Carlson Martha W. Hanscom Dr. and Mrs. Herbert A. Marra Mr. and Mrs. Thomas E. Roth Christopher L. and Ruby D. Wilde Guy and Arlene Ott Michael and Lynn Garvey Andrew and Emily Warden IN* IN = Innovators Network Eleanor E. and Ellen C. Carnwath JoAnne Hansen Hank, Fuchsia and Marcia Martin Milton and Ruth Rubin Carl H. Wittenberg John and Jean Rolfe $50,000 - $99,999 glassybaby Mr. Richard Warner Douglas A. Case Mary Alberta Hargrove Joan A. Martin Mr. and Mrs. Allan N. Rumpf Ms. Dawn M. Wood Michael B. Rubin Drive Fore the Cure Northwest Foundation Mr. and Mrs. Robert Gordon Cherie R. Warren IN In FY12, giving to the Center included Hazel E. Case Andy and Carol Harris Mrs. Alma L. McDonald Mr. Robert H. Rutledge Lois M. Woodcock and Richard H. Woodcock Nancy and Michael Ryan Muckleshoot Indian Tribe Mark Groudine and Cynthia Putnam Mr. and Mrs. Larry M. Watkins 22 anonymous benefactors. Mary E. Cederlund Mr. and Mrs. Robert Harrower, Jr. Marcia McGreevey-Lewis and Mary Ann Sage and Gordon R. Sinning Penny M. Woods Skip and Marilla Satterwhite H&M Electric Inc. Yonnie Watkins IN Cora Chads Mrs. Mary E. Harvill Robert D. Lewis, M.D. Cynthia and Gerry Salkowski Sarah Woods Gregory and Charlene Steinhauer $25,000 - $49,999 Harold M. Harlan Jim and Diane Watson Mylo and Marion Charlston Peder and Theodora Haslestad Douglas G. and Ruth J. McKnight Sam and Betty LeBid Foundation Mrs. Arline B. Zidell Dr. and Mrs. E. Donnall Thomas Microsoft Corporation Ms. Jessica M. Harlow Joseph and Janet Zinn THANK YOU.23 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT PRIVATE CONTRIBUTORS FISCAL YEAR 2012

High-Cedars Ladies Club Mr. Darren Rozendaal FINANCIAL SUMMARY FRED HUTCHINSON CANCER RESEARCH CENTER Fred and Dawn Hines Mr. Bruno A. Rudolf Iva and Lawrence Hirsch School Employees Credit Union of Washington Ms. Barbara L. Hopkins Charles and Mary Ann Schroeter FRED HUTCHINSON CANCER RESEARCH CENTER BOARDS Ms. Jonelle M.C. Johnson Ms. Virginia L. Schwedler FISCAL YEAR 2012 Rich and Aimee Jones Seattle Aquarium Mr. and Mrs. James G. Kibble The Seattle Foundation (IN THOUSANDS OF DOLLARS) JULY 2011 – JUNE 2012 Kitsap Destruction Derby Association Sila Solutions Group Kvichak Marine Industries, Inc. Skagit Farmers Supply L & L Exhibition Management, Inc. Mr. and Mrs. Donald Sly BOARD OF TRUSTEES BOARD OF AMBASSADORS SENIOR COUNCIL Ms. Janet L. Levinger Mr. David G. Smith Steve Davis, Chair Carl Behnke, Co-Chair Ken Greenbaum Gilbert Stanley Omenn, M.D., Ph.D.* William W. Christoffersen Ms. Kristine A. Logan Karen Marcotte Solimano and Doug Williams, Ph.D., Vice Chair Patricia McDonald*, Co-Chair Kathryn Harris Nancy Pellegrino Vincent F. Coviello, Jr. Robert MacAulay and Keri Ellison James P. Solimano OPERATING REVENUES Doug Walker, Immediate Past Chair Deborah Haug Charlotte Reed David Frohnmayer Ms. Lisa M. Magnusson Mr. and Mrs. Justin Swan FISCAL YEAR 2012 Karl Ege, Treasurer Connie Anderson* Bob Herbold Rao Remala Denver C. Ginsey Mr. Matt Manahan Mr. and Mrs. Donald P. Swisher n Research Grants Ric Anderson, Secretary Robert M. Arnold* Peter Horvitz Satya Remala Slade Gorton Ms. Susan A. Margolis Mrs. Deborah J. Tallman and Contracts $350,372 (80%) Robert Bayley* John Hutchinson* Jean Rolfe* Irving Haug Market Optical Ms. Myra H. Tanita Holly Dillon Ron Bayley Stuart R. Hutchinson, M.D. Keith Schorsch Frank H. Hopkins Mr. and Mrs. Jeremy Mattox Mr. Kris Thirasawat n Other Income 50,595 (11%) Kari Glover Sally Skinner Behnke* Rich Jones Harriet Shrontz* Kay Jones McAdams Wright & Ragen Incorporated Mr. Edward L. Tropp n Net Contributions 27,123 (6%) Stephen Graham Ronald Berenson, M.D. Karmann Kaplan Alee Spencer Stanley M. Little, Jr. Mr. and Mrs. Richard B. McCune Mr. Kent Van Valkenburgh Ron Howell Debbie Bevier* Rich Kaplan Charlene Steinhauer David Lycette Michael and Neal McMahan Vanguard Charitable Endowment Program n Investment Income 11,197 (3%) Henry James Eric Bremner* Reg Koehler* Stephen V. Sundborg, S.J. George Rathmann, Ph.D. Morgan Stanley Ms. Leah Wiiest Rick Koffey Philip Bussey Yvonne Lamey Gerald R. Swanson* Charles E. Riley Dr. Michael Mulhern David and Jace Williams Richard B. McCune Rudolph F. Crew, Ed.D. Don Listwin Robert V. Taylor James F. Ryan Shan and Lee Mullin Woodland Park Zoo Society Robert Nelsen Edward D. Davila, M.D. Jeff Maxwell Barbara Thrasher The Honorable Charles Z. Smith Network For Good Peter Neupert David R. Davis, M.D.* Neil McReynolds* Bonnie Towne* William J. Sullivan, S.J. Richard and Greta Noffsinger In FY12, giving to SCCA included Charles Nolan, M.D. Barbara Ells* Joan Morse James Weymouth George Walker Ms. Alice E. Nordwall two anonymous benefactors. Paula Reynolds Phelps Fisher* Karen Moyer Roberta Weymouth Wallace Opdycke and Nicola Opdycke Jim Sinegal Cathryn Fortune Shan Mullin* Mary H. Wiese * Denotes dual membership on Board Pioneer Human Services Vijay Vashee Edward Fritzky Craig Mundie Scott Wilson of Ambassadors and Senior Council Brooks and Suzanne Ragen Robert L. Gerth Sally Narodick Cindy Zehnder* Rainier Investment Management Inc OPERATING EXPENSES Fredda Goldfarb Martin Nelson Kathleen R. Randall FISCAL YEAR 2012 Steven Goldfarb Ambassador Della M. Newman* Ms. Jana K. Rasmussen n Program Services Robert Allen Design – Research $336,658 (77%) Dr. Sharon Romm Ronald McDonald House Charities of n Facilities and Western Washington & Alaska Administration 92,231 (21%) LEADERSHIP A N N U A L R E P O R T n Fundraising 6,601 (2%) Published by the External Affairs Larry Corey, M.D. Julie McElrath, M.D., Ph.D. Ulrich Mueller, Ph.D. and Communications Department President and Director Senior Vice President Vice President Fred Hutchinson Cancer Research Center Co-Director, Vaccine and Industry Relations and Mail Stop J5-200 Mark Groudine, M.D., Ph.D. Infectious Disease Division Clinical Research Support PO Box 19024 Executive Vice President and Seattle, WA 98109-1024 Deputy Director Ross Prentice, Ph.D. Han Nachtrieb 206.667.4399 Senior Vice President Vice President www.fredhutch.org Myra Tanita Director, Public Health Sciences Division Human Resources SOURCES OF CONTRIBUTIONS Executive Vice President and © 2012 Fred Hutchinson Cancer Research Center FISCAL YEAR 2012 Chief Operating Officer Tony Bozzuti Scott Rusch Gordon Todd n Planned Giving 28% Vice President and Vice President Editor Frederick Appelbaum, M.D. Chief Information Officer Facilities and Operations n Barbara Hoberecht Major Gifts 25% Senior Vice President Art Director n Foundation Relations 17% Director, Clinical Research Division Susan Dolbert, Ph.D. Doug Shaeffer Vice President Vice President Stefanie Felix n Annual Giving 13% Jonathan Cooper, Ph.D. Development General Counsel Susie Fitzhugh n Special Events 9% Senior Vice President Dean Forbes Director, Basic Sciences Division Linda Gainer Paul Woloshin, Ph.D. Ron Wurzer n Special Gifts 8% Vice President Vice President Photographers Denise Galloway, Ph.D. External Affairs and Communications Shared Resources Brad Broberg Interim Director, Human Biology Ignacio Lobos Division Randy Main Justin Matlick Vice President and Colleen Steelquist Chief Financial Officer Gordon Todd Rachel Tompa Writers 24 FRED HUTCHINSON CANCER RESEARCH CENTER | 2012 ANNUAL REPORT www.fredhutch.org

1100 Fairview Ave. N., Mail Stop J5-200, PO Box 19024, Seattle, WA 98109-1024 206.667.4399 1.800.279.1618