Self-Study Report Department of Biochemistry and Biophysics External Academic Program Review, April 2021
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Frontiers of Quantum and Mesoscopic Thermodynamics 29 July - 3 August 2013, Prague, Czech Republic
Frontiers of Quantum and Mesoscopic Thermodynamics 29 July - 3 August 2013, Prague, Czech Republic Under the auspicies of Ing. Milosˇ Zeman President of the Czech Republic Milan Stˇ echˇ President of the Senate of the Parliament of the Czech Republic Prof. Ing. Jirˇ´ı Drahos,ˇ DrSc., dr. h. c. President of the Academy of Sciences of the Czech Republic Dominik Cardinal Duka OP Archbishop of Prague Supported by • Committee on Education, Science, Culture, Human Rights and Petitions of the Senate of the Parliament of the Czech Republic • Institute of Physics, the Academy of Sciences of the Czech Republic • Institute for Theoretical Physics, University of Amsterdam, The Netherlands • Department of Physics, Texas A&M University, USA • Institut de Physique Theorique,´ CEA/CNRS Saclay, France Topics • Foundations of quantum physics • Non-equilibrium statistical physics • Quantum thermodynamics • Quantum measurement, entanglement and coherence • Dissipation, dephasing, noise and decoherence • Quantum optics • Macroscopic quantum behavior, e.g., cold atoms, Bose-Einstein condensates • Physics of quantum computing and quantum information • Mesoscopic, nano-electromechanical and nano-optical systems • Biological systems, molecular motors • Cosmology, gravitation and astrophysics Scientific Committee Chair: Theo M. Nieuwenhuizen (University of Amsterdam) Co-Chair: Vaclav´ Spiˇ ckaˇ (Institute of Physics, Acad. Sci. CR, Prague) Raymond Dean Astumian (University of Maine, Orono) Roger Balian (IPhT, Saclay) Gordon Baym (University of Illinois at Urbana -
Guide to Publication Policies of the Nature Journals
GUIDE TO PUBLICATION POLICIES OF THE NATURE JOURNALS Last updated on 30 April 2009. Editorial Policies NATURE JOURNALS' POLICIES ON PUBLICATION ETHICS Nature journals' authorship policy Being an author The Nature journals do not require all authors of a research paper to sign the letter of submission, nor do they impose an order on the list of authors. Submission to a Nature journal is taken by the journal to mean that all the listed authors have agreed all of the contents. The corresponding (submitting) author is responsible for having ensured that this agreement has been reached, and for managing all communication between the journal and all co-authors, before and after publication. Any changes to the author list after submission, such as a change in the order of the authors, or the deletion or addition of authors, needs to be approved by a signed letter from every author. Responsibilities of senior team members on multi-group collaborations The editors at the Nature journals assume that at least one member of each collaboration, usually the most senior member of each submitting group or team, has accepted responsibility for the contributions to the manuscript from that team. This responsibility includes, but is not limited to: (1) ensuring that original data upon which the submission is based is preserved and retrievable for reanalysis; (2) approving data presentation as representative of the original data; and (3) foreseeing and minimizing obstacles to the sharing of data, materials, algorithms or reagents described in the work. Author contributions statementsAuthors are required to include a statement of responsibility in the manuscript that specifies the contribution of every author. -
Role of Nlrs in the Regulation of Type I Interferon Signaling, Host Defense and Tolerance to Inflammation
International Journal of Molecular Sciences Review Role of NLRs in the Regulation of Type I Interferon Signaling, Host Defense and Tolerance to Inflammation Ioannis Kienes 1, Tanja Weidl 1, Nora Mirza 1, Mathias Chamaillard 2 and Thomas A. Kufer 1,* 1 Department of Immunology, Institute for Nutritional Medicine, University of Hohenheim, 70599 Stuttgart, Germany; [email protected] (I.K.); [email protected] (T.W.); [email protected] (N.M.) 2 University of Lille, Inserm, U1003, F-59000 Lille, France; [email protected] * Correspondence: [email protected] Abstract: Type I interferon signaling contributes to the development of innate and adaptive immune responses to either viruses, fungi, or bacteria. However, amplitude and timing of the interferon response is of utmost importance for preventing an underwhelming outcome, or tissue damage. While several pathogens evolved strategies for disturbing the quality of interferon signaling, there is growing evidence that this pathway can be regulated by several members of the Nod-like receptor (NLR) family, although the precise mechanism for most of these remains elusive. NLRs consist of a family of about 20 proteins in mammals, which are capable of sensing microbial products as well as endogenous signals related to tissue injury. Here we provide an overview of our current understanding of the function of those NLRs in type I interferon responses with a focus on viral infections. We discuss how NLR-mediated type I interferon regulation can influence the development of auto-immunity and the immune response to infection. Citation: Kienes, I.; Weidl, T.; Mirza, Keywords: NOD-like receptors; Interferons; innate immunity; immune regulation; type I interferon; N.; Chamaillard, M.; Kufer, T.A. -
2014 Oakland A’S
2014 Oakland A’s Supplemental Bios includes bios for: Bryan Anderson, Adam Dunn, Sam Fuld, Jonny Gomes, Jason Hammel, Jon Lester, Jeff Samardzija and Geovany Soto The entire A’s Media Guide is available at http://pressbox.athletics.com and http://pressbox.mlb.com zona, a single off Dan Haren…collected his first RBI April 26 vs. Atlanta before being optioned back to BRYAN ANDERSON 45 Memphis following the game…was recalled for the remainder of the season Aug. 18…went 2-for-4 with a RBI Sept. 29 vs. Pittsburgh …hit a career-high 12 home runs over 82 games with Memphis…threw CATCHER out 31.4 percent (16-of-51) of attempted basestealers, the second-best mark in the PCL…was named Height/Weight: 6-1 / 200 Bats/Throws: Left / Right the Cardinals Minor League Player of the Month for June after hitting .344 with four home runs and 14 Birthdate: December 16, 1986 Opening Day Age: 27 RBI…went 11-for-24 (.458) with two homers and six RBI over a six-game game span from June 2-11. Birthplace/Resides: Thousand Oaks, California / Simi Valley, Califor- nia 2009—Batted .251 with five home runs and 13 RBI in 58 games between Memphis and the GCL Cardi- Major League Service: 128 days nals…missed the final 71 games of the season due to a separated left shoulder…threw out 27.8 percent Obtained: Acquired from the Cincinnati Reds for international cash, (15-of-54) of attempted basestealers…appeared in 14 games with Surprise in the Arizona Fall League. -
The Nature Index Journals
The Nature Index journals The current 12-month window on natureindex.com includes data from 57,681 primary research articles from the following science journals: Advanced Materials (1028 articles) American Journal of Human Genetics (173 articles) Analytical Chemistry (1633 articles) Angewandte Chemie International Edition (2709 articles) Applied Physics Letters (3609 articles) Astronomy & Astrophysics (1780 articles) Cancer Cell (109 articles) Cell (380 articles) Cell Host & Microbe (95 articles) Cell Metabolism (137 articles) Cell Stem Cell (100 articles) Chemical Communications (4389 articles) Chemical Science (995 articles) Current Biology (440 articles) Developmental Cell (204 articles) Earth and Planetary Science Letters (608 articles) Ecology (259 articles) Ecology Letters (120 articles) European Physical Journal C (588 articles) Genes & Development (193 articles) Genome Research (184 articles) Geology (270 articles) Immunity (159 articles) Inorganic Chemistry (1345 articles) Journal of Biological Chemistry (2639 articles) Journal of Cell Biology (229 articles) Journal of Clinical Investigation (298 articles) Journal of Geophysical Research: Atmospheres (829 articles) Journal of Geophysical Research: Oceans (493 articles) Journal of Geophysical Research: Solid Earth (520 articles) Journal of High Energy Physics (2142 articles) Journal of Neuroscience (1337 articles) Journal of the American Chemical Society (2384 articles) Molecular Cell (302 articles) Monthly Notices of the Royal Astronomical Society (2946 articles) Nano Letters -
Download Preview
DETROIT TIGERS’ 4 GREATEST HITTERS Table of CONTENTS Contents Warm-Up, with a Side of Dedications ....................................................... 1 The Ty Cobb Birthplace Pilgrimage ......................................................... 9 1 Out of the Blocks—Into the Bleachers .............................................. 19 2 Quadruple Crown—Four’s Company, Five’s a Multitude ..................... 29 [Gates] Brown vs. Hot Dog .......................................................................................... 30 Prince Fielder Fields Macho Nacho ............................................................................. 30 Dangerfield Dangers .................................................................................................... 31 #1 Latino Hitters, Bar None ........................................................................................ 32 3 Hitting Prof Ted Williams, and the MACHO-METER ......................... 39 The MACHO-METER ..................................................................... 40 4 Miguel Cabrera, Knothole Kids, and the World’s Prettiest Girls ........... 47 Ty Cobb and the Presidential Passing Lane ................................................................. 49 The First Hammerin’ Hank—The Bronx’s Hank Greenberg ..................................... 50 Baseball and Heightism ............................................................................................... 53 One Amazing Baseball Record That Will Never Be Broken ...................................... -
Carbon Dioxide Adsorption by Metal Organic Frameworks (Synthesis, Testing and Modeling)
Western University Scholarship@Western Electronic Thesis and Dissertation Repository 8-8-2013 12:00 AM Carbon Dioxide Adsorption by Metal Organic Frameworks (Synthesis, Testing and Modeling) Rana Sabouni The University of Western Ontario Supervisor Prof. Sohrab Rohani The University of Western Ontario Graduate Program in Chemical and Biochemical Engineering A thesis submitted in partial fulfillment of the equirr ements for the degree in Doctor of Philosophy © Rana Sabouni 2013 Follow this and additional works at: https://ir.lib.uwo.ca/etd Part of the Other Chemical Engineering Commons Recommended Citation Sabouni, Rana, "Carbon Dioxide Adsorption by Metal Organic Frameworks (Synthesis, Testing and Modeling)" (2013). Electronic Thesis and Dissertation Repository. 1472. https://ir.lib.uwo.ca/etd/1472 This Dissertation/Thesis is brought to you for free and open access by Scholarship@Western. It has been accepted for inclusion in Electronic Thesis and Dissertation Repository by an authorized administrator of Scholarship@Western. For more information, please contact [email protected]. i CARBON DIOXIDE ADSORPTION BY METAL ORGANIC FRAMEWORKS (SYNTHESIS, TESTING AND MODELING) (Thesis format: Integrated Article) by Rana Sabouni Graduate Program in Chemical and Biochemical Engineering A thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy The School of Graduate and Postdoctoral Studies The University of Western Ontario London, Ontario, Canada Rana Sabouni 2013 ABSTRACT It is essential to capture carbon dioxide from flue gas because it is considered one of the main causes of global warming. Several materials and various methods have been reported for the CO2 capturing including adsorption onto zeolites, porous membranes, and absorption in amine solutions. -
Downloaded At
THE BROWN MOMENT IN TAIWAN: MAKING SENSE OF THE LAW AND POLITICS OF THE TAIWANESE SAME-SEX MARRIAGE CASE IN A COMPARATIVE LIGHT Ming-Sung Kuo & Hui-Wen Chen+ The Taiwan Constitutional Court (TCC) recently issued a landmark decision in Interpretation No. 748 (the Same-Sex Marriage Case), declaring the definition of marriage as a gender-differentiated union of a man and a woman under the Civil Code unconstitutional and setting the stage for Taiwan to become the first in Asia to legalize same-sex marriage. This decision has been compared to Obergefell v. Hodges. However, reading Obergefell in the broad context of the gay rights movement and the role of judicial review in Taiwanese constitutional politics, we challenge this analogy. Due to the discrepancy between the social movement and the law in the fight for constitutional rights for gays and lesbians in Taiwan, the Same-Sex Marriage Case is Taiwan’s Brown v. Board of Education moment in her constitutional law and politics. To make sense of the law and politics of the Same Sex Marriage Case, we evaluate its political context and the text and style in its reasoning. We observe a discrepancy between law and politics in the pursuit of the constitutional rights of gays and lesbians in Taiwan. The rise of same-sex marriage to the top of the antidiscrimination agenda resulted from the continuous effort of gay rights activists, while the TCC watched this movement from the sidelines until the Same-Sex Marriage Case. This case thus mirrors Brown in two respects. First, the role of the TCC has been publicly questioned after its Brown-like contentious decision on the issue of same-sex marriage. -
Post-Transcriptional Inhibition of Luciferase Reporter Assays
THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 287, NO. 34, pp. 28705–28716, August 17, 2012 © 2012 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A. Post-transcriptional Inhibition of Luciferase Reporter Assays by the Nod-like Receptor Proteins NLRX1 and NLRC3* Received for publication, December 12, 2011, and in revised form, June 18, 2012 Published, JBC Papers in Press, June 20, 2012, DOI 10.1074/jbc.M111.333146 Arthur Ling‡1,2, Fraser Soares‡1,2, David O. Croitoru‡1,3, Ivan Tattoli‡§, Leticia A. M. Carneiro‡4, Michele Boniotto¶, Szilvia Benko‡5, Dana J. Philpott§, and Stephen E. Girardin‡6 From the Departments of ‡Laboratory Medicine and Pathobiology and §Immunology, University of Toronto, Toronto M6G 2T6, Canada, and the ¶Modulation of Innate Immune Response, INSERM U1012, Paris South University School of Medicine, 63, rue Gabriel Peri, 94276 Le Kremlin-Bicêtre, France Background: A number of Nod-like receptors (NLRs) have been shown to inhibit signal transduction pathways using luciferase reporter assays (LRAs). Results: Overexpression of NLRX1 and NLRC3 results in nonspecific post-transcriptional inhibition of LRAs. Conclusion: LRAs are not a reliable technique to assess the inhibitory function of NLRs. Downloaded from Significance: The inhibitory role of NLRs on specific signal transduction pathways needs to be reevaluated. Luciferase reporter assays (LRAs) are widely used to assess the Nod-like receptors (NLRs)7 represent an important class of activity of specific signal transduction pathways. Although pow- intracellular pattern recognition molecules (PRMs), which are erful, rapid and convenient, this technique can also generate implicated in the detection and response to microbe- and dan- www.jbc.org artifactual results, as revealed for instance in the case of high ger-associated molecular patterns (MAMPs and DAMPs), throughput screens of inhibitory molecules. -
Off the Beaten Track
Off the Beaten Track To have your recording considered for review in Sing Out!, please submit two copies (one for one of our reviewers and one for in- house editorial work, song selection for the magazine and eventual inclusion in the Sing Out! Resource Center). All recordings received are included in “Publication Noted” (which follows “Off the Beaten Track”). Send two copies of your recording, and the appropriate background material, to Sing Out!, P.O. Box 5460 (for shipping: 512 E. Fourth St.), Bethlehem, PA 18015, Attention “Off The Beaten Track.” Sincere thanks to this issue’s panel of musical experts: Richard Dorsett, Tom Druckenmiller, Mark Greenberg, Victor K. Heyman, Stephanie P. Ledgin, John Lupton, Angela Page, Mike Regenstreif, Seth Rogovoy, Ken Roseman, Peter Spencer, Michael Tearson, Theodoros Toskos, Rich Warren, Matt Watroba, Rob Weir and Sule Greg Wilson. that led to a career traveling across coun- the two keyboard instruments. How I try as “The Singing Troubadour.” He per- would have loved to hear some of the more formed in a variety of settings with a rep- unusual groupings of instruments as pic- ertoire that ranged from opera to traditional tured in the notes. The sound of saxo- songs. He also began an investigation of phones, trumpets, violins and cellos must the music of various utopian societies in have been glorious! The singing is strong America. and sincere with nary a hint of sophistica- With his investigation of the music of tion, as of course it should be, as the Shak- VARIOUS the Shakers he found a sect which both ers were hardly ostentatious. -
Deborah Barylski
DEBORAH BARYLSKI CASTING DIRECTOR (310) 314-9116 (h) SELECTED CREDITS (310) 795-2035 (c) FEATURE FILMS [email protected] PASTIME* Prod: Robin Armstrong, Eric Young Dir: R. Armstrong *Winner, Audience Award, Sundance MOVIES FOR TELEVISION ALLEY CATS STRIKE (Disney Cannel) Execs: Carol Ames, Don Safran, Michael Cieply Dir: Rod Daniel A PLACE TO BE LOVED (CBS) Exec. Producer: Beth Polson Dir: Sandy Smolan A MESSAGE FROM HOLLY (CBS) Exec. Producer: Beth Polson Dir: Rod Holcomb BACK TO THE STREETS OF SF (NBC) Exec. Producer: Diana Kerew, M. Goldsmith Dir: Mel Damski GUESS WHO'S COMING FOR XMAS? Exec. Producer: Beth Polson Dir: Paul Schneider TELEVISION: PILOT & SERIES *Winner, EMMY and Artios Awards for Casting for a Comedy Series, 2004 **Artios Award nomination SAINT GEORGE Execs: M.Williams,D. McFadzean,G.Lopez,M.Rotenberg Lionsgate/FX BACK OF THE CLASS Execs: Hugh Fink, Porter, Dionne, Weiner Nickelodeon DIRTY WORK (Won New Media Emmy) Execs: Zach Schiff-Abrams, Jackie Turnure, A. Shure Fourth Wall Studios THE MIDDLE Execs: Eileen Heisler, DeAnn Heline Warners/ABC UNTITLED DANA GOULD PROJECT Execs: D. Gould, Mike Scully, T. Lassally, D. Becky Warners/ABC THE EMANCIPATION OF ERNESTO Execs: Emily Kapnek, Wilmer Valderama 20th/Fox STARTING UNDER Exec. Bruce Helford/Mohawk Warners/Fox HACKETT Execs: Sonnenfeld, Moss, Timberman, Carlson Sony/FBC NICE GIRLS DON’T GET THE CORNER OFFICE. Execs: Nevins, Sternin, Ventimilia Imagine & 20th/ABC THE WAR AT HOME Exec. Rob Lotterstein, M.Schultheis, M.Hanel 20th/Warners/Fox KITCHEN CONFIDENTIAL Execs: D. Star, D. Hemingson, & New Line Fox/FBC THE ROBINSON BROTHERS Exec. Mark O’Keefe, Adelstein, Moritz,Parouse 20th/ORIGINAL/FBC ARRESTED DEVELOPMENT* Exec. -
WO 2015/028850 Al 5 March 2015 (05.03.2015) P O P C T
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2015/028850 Al 5 March 2015 (05.03.2015) P O P C T (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, C07D 519/00 (2006.01) A61P 39/00 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, C07D 487/04 (2006.01) A61P 35/00 (2006.01) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, A61K 31/5517 (2006.01) A61P 37/00 (2006.01) HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, A61K 47/48 (2006.01) KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (21) International Application Number: OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, PCT/IB2013/058229 SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, (22) International Filing Date: TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, 2 September 2013 (02.09.2013) ZW. (25) Filing Language: English (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (26) Publication Language: English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, (71) Applicant: HANGZHOU DAC BIOTECH CO., LTD UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, [US/CN]; Room B2001-B2019, Building 2, No 452 Sixth TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Street, Hangzhou Economy Development Area, Hangzhou EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, City, Zhejiang 310018 (CN).