Tongue, Salivary Glands (Additional Images for the Lecture)

Total Page:16

File Type:pdf, Size:1020Kb

Tongue, Salivary Glands (Additional Images for the Lecture) Tongue, salivary glands (for ED I.) additional images for the lecture Dr. Ágota Ádám February 22, 2018. Part I. - Tongue Dorsum of the tongue Ventral surface of the tongue Ant. lingual glands fimbriated fold (plica fimbriata) Developmental disorder: ‘tongue-tied’ baby frenulum (ankyloglossia) Sublingual caruncle! Deep lingual a. and v.; (opening of lingual n. submandibular and sublingual ducts!) Sublingual fold Muscles of the tongue Motor innervation: hypoglossal nerve (CN XII.)! (palatoglossus) (soft palate muscles!) styloglossus genioglossus The ONLY muscle that hyoglossus protrudes the tongue! Innervation of the tongue SPECIAL (TASTE) SENSATION GENERAL (SOMATIC) SENSATION Motor innervation: hypoglossal n. (CN. XII.) N. X. N. X. a, normal situation N. IX. N. IX. b, unilateral hypoglossal nerve palsy (paralysed genioglossus on affected side) a, b, chorda tympani lingual n. (from CN V/3) (from CN VII.) Vessels and nerves of the tongue lingual n. (from CN V/3) glossopharyngeal n. submandibular ganglion lingual a. (from ECA) and lingual v. hypoglossal n. Lateral lingual sulcus (groove) Borders: Medial: hyoglossus m. lateral and inferior: mylohyoid m. superior: mucosa of oral cavity Contents: •N. XII. •n. lingualis (from V/3) •submandibular duct •sublingual gland lingual nerve sublingual gland sublingual caruncle medial pterygoid submandibular gland submandibular duct The lymphatic drainage of the tongue Anterior 2/3: to central and marginal lymph vessels; post. 1/3: to dorsal lymph vessels. The lymph nodes receive drainage from both ipsilateral and contralateral sides!!! UPPER DEEP CERVICAL LYMPH NODES: (around the int. jugular v.) submandibular jugulo-gastric node lymph nodes jugulo-omohyoid node submental lymph nodes LOWER DEEP CERVICAL LYMPH NODES Papillae of the tongue filiform fungiform foliate circumvallate taste buds Taste bud von Ebner’s glands (serous) Examples of diseases showing clinical signs on the tongue median rhomboid glossitis ‘strawberry tongue’ ‘geographic glossitis’ (Candida infection) (scarlet fever) (cause unknown) leukoplakia oral cancer on pre-cancerous the side of the lesion, due to tongue or permanent irritation (smoking (!) ) Part II. - Salivary glands 3 major salivary glands: parotid duct (Stensen) parotid gland sublingual gland buccinator m. submandibular gland Parotid nest (drawing!!!) posterior border: SCM, post. belly of digastric medial border: ‘stylo-muscles’ anterior border: masseter, ramus of mandible, med. pterygoid lateral border: parotideomasseteric fascia Openings of salivary glands to the oral cavity (!) Submandibular duct (of Wharton) (1/side): to proper oral cavity, sublingual caruncula Sublingual ducts (8-20): to proper oral cavity, the largest duct (of Bartholin) joins the submandibular duct and opens into the sublingual caruncula, the smaller ones (of Rivinius) open at the sublingual fold/plica Parotid duct (of Stensen) (1/side): to oral vestibule, on the buccal mucosa, opposite to the upper 2nd molar tooth RELATIVE ISOLATION of the teeth from saliva ABSOLUTE ISOLATION upper posterior teeth – isolation from the opening of Stensen’s duct lower posterior teeth rubber dental dam isolation of lower front teeth from the sublingual caruncle Minor salivary glands Bimanual examination of the salivary glands In addition to the 3 major paired glands, 500-1000 minor glands also secrete saliva (5-8% of total) into the oral cavity Labial glands submandibular (mixed) gland Palatine glands (mucous) lymph node Pharyngeal glands (mucous) Sublingual gland Histology of salivary glands acinus (with myoepithelial cells around) – intercalated duct – striated duct – interlobular duct - excretory duct submandibular gland sublingual gland parotid gland (mixed; serous > mucous) mixed; mucous > serous) (pure serous) serous acini mucous acinus striated duct mucous acinus striated duct serous acini Submandibular gland – more serous acini! adipocytes striated duct Sublingual gland – more mucous acini! striated duct Salivary stones (sialolithiasis) sialendoscopy Thank you for your attention! .
Recommended publications
  • Parotid and Mandibular Salivary Glands Segmentation of the One Humped Dromedary Camel (Camelus Dromedarius)
    Int. J. Adv. Res. Biol. Sci. (2017). 4(11): 32-41 International Journal of Advanced Research in Biological Sciences ISSN: 2348-8069 www.ijarbs.com DOI: 10.22192/ijarbs Coden: IJARQG(USA) Volume 4, Issue 11 - 2017 Research Article DOI: http://dx.doi.org/10.22192/ijarbs.2017.04.11.005 Parotid and Mandibular Salivary Glands Segmentation Of The One Humped Dromedary Camel (Camelus dromedarius) Hamdy M. Rezk and Nora A. Shaker* Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Cairo University, Egypt *Corresponding author: [email protected] Abstract The present study provides detailed anatomical description of the parotid and mandibular salivary glands of the one humped camel with their segmentation based on arterial blood supply and salivary ducts; to facilitate partial removal of the pathologic gland. The shape, position, relations and blood supply of both salivary glands with their ducts were studied on six cadaveric heads. The mandibular and parotid ducts were injected with Urographin® as contrast medium; through inserting the catheter into their openings in the oral cavity; then applying lateral radiography immediately after the injection. The common carotid arteries were injected with red Latex Neoprene and dissected. The parotid gland was irregular rectangular and had five processes while the mandibular gland was irregular triangular with rounded proximal and pointed distal extremity. The parotid duct enters the oral cavity on the cheek opposite the upper 4th molar tooth. The mandibular duct opens in the oral cavity at the sublingual caruncles on the sublingual floor, just about 2cm cranial to frenulum linguae. Both The parotid and the mandibular salivary glands could be divided into four segments.
    [Show full text]
  • Anatomy-Nerve Tracking
    INJECTABLES ANATOMY www.aestheticmed.co.uk Nerve tracking Dr Sotirios Foutsizoglou on the anatomy of the facial nerve he anatomy of the human face has received enormous attention during the last few years, as a plethora of anti- ageing procedures, both surgical and non-surgical, are being performed with increasing frequency. The success of each of those procedures is greatly dependent on Tthe sound knowledge of the underlying facial anatomy and the understanding of the age-related changes occurring in the facial skeleton, ligaments, muscles, facial fat compartments, and skin. The facial nerve is the most important motor nerve of the face as it is the sole motor supply to all the muscles of facial expression and other muscles derived from the mesenchyme in the embryonic second pharyngeal arch.1 The danger zone for facial nerve injury has been well described. Confidence when approaching the nerve and its branches comes from an understanding of its three dimensional course relative to the layered facial soft tissue and being aware of surface anatomy landmarks and measurements as will be discussed in this article. Aesthetic medicine is not static, it is ever evolving and new exciting knowledge emerges every day unmasking the relationship of the ageing process and the macroscopic and microscopic (intrinsic) age-related changes. Sound anatomical knowledge, taking into consideration the natural balance between the different facial structures and facial layers, is fundamental to understanding these changes which will subsequently help us develop more effective, natural, long-standing and most importantly, safer rejuvenating treatments and procedures. The soft tissue of the face is arranged in five layers: 1) Skin; 2) Subcutaneous fat layer; 3) Superficial musculoaponeurotic system (SMAS); 4) Areolar tissue or loose connective tissue (most clearly seen in the scalp and forehead); 5) Deep fascia formed by the periosteum of facial bones and the fascial covering of the muscles of mastication (lateral face).
    [Show full text]
  • Head and Neck
    DEFINITION OF ANATOMIC SITES WITHIN THE HEAD AND NECK adapted from the Summary Staging Guide 1977 published by the SEER Program, and the AJCC Cancer Staging Manual Fifth Edition published by the American Joint Committee on Cancer Staging. Note: Not all sites in the lip, oral cavity, pharynx and salivary glands are listed below. All sites to which a Summary Stage scheme applies are listed at the begining of the scheme. ORAL CAVITY AND ORAL PHARYNX (in ICD-O-3 sequence) The oral cavity extends from the skin-vermilion junction of the lips to the junction of the hard and soft palate above and to the line of circumvallate papillae below. The oral pharynx (oropharynx) is that portion of the continuity of the pharynx extending from the plane of the inferior surface of the soft palate to the plane of the superior surface of the hyoid bone (or floor of the vallecula) and includes the base of tongue, inferior surface of the soft palate and the uvula, the anterior and posterior tonsillar pillars, the glossotonsillar sulci, the pharyngeal tonsils, and the lateral and posterior walls. The oral cavity and oral pharynx are divided into the following specific areas: LIPS (C00._; vermilion surface, mucosal lip, labial mucosa) upper and lower, form the upper and lower anterior wall of the oral cavity. They consist of an exposed surface of modified epider- mis beginning at the junction of the vermilion border with the skin and including only the vermilion surface or that portion of the lip that comes into contact with the opposing lip.
    [Show full text]
  • Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases
    International Scholarly Research Network ISRN Dentistry Volume 2011, Article ID 457567, 6 pages doi:10.5402/2011/457567 Case Report Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases Toru Yanagawa,1 Akira Yamaguchi,2 Hiroyuki Harada,3 Kenji Yamagata,1 Naomi Ishibashi,1 Masayuki Noguchi,4 Kojiro Onizawa,1 and Hiroki Bukawa1 1 Department of Oral and Maxillofacial Surgery, Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan 2 Section of Oral Pathology, Division of Oral Health Sciences, Department of Oral Restitution, Graduate School Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan 3 Section of Oral and Maxillofacial Surgery, Division of Oral Health Sciences, Department of Oral Restitution, Graduate School Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan 4 Department of Pathology, Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan Correspondence should be addressed to Toru Yanagawa, [email protected] Received 25 October 2010; Accepted 5 December 2010 Academic Editor: G. L. Lodi Copyright © 2011 Toru Yanagawa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cheilitis glandularis (CG) is a rare disorder characterized by swelling of the lip with hyperplasia of the labial salivary glands. CG is most frequently encountered in the lower lip, in middle-aged to older Caucasian men; however Asian cases were rarely reported.
    [Show full text]
  • Glands: a Correlation in Postmortem Subjects
    J. clin. Path., 1970, 23, 690-694 Lymphocytic sialadenitis in the major and minor glands: a correlation in postmortem subjects D. M. CHISHOLM, J. P. WATERHOUSE, AND D. K. MASON From the Department of Oral Medicine and Pathology, University of Glasgow Dental Hospital and School, Glasgow, Scotland, and the Department of Oral Pathology, University ofIllinois, Chicago, USA SYNOPSIS In the present investigation, the prevalence offocal lymphocytic adenitis in the submandibular salivary gland was observed in a series of 116 postmortem subjects after suitable exclusions had been made. Focal lymphocytic adenitis could not be demonstrated in the labial salivary glands. The degree of lymphocytic infiltration in the labial salivary glands is positively correlated with the level of focal lymphocytic adenitis in the submandibular glands in the same subject. Lymphocytic foci and lymphocytic infiltrations found under these circumstances are probably related. This finding provides conceptual support for the examina- tion, by biopsy, of the labial glands in patients suspected of Sjogren's syndrome. The aim of the present study was to investigate muscle layer of the lower lip were excised at the prevalence and degree of lymphocytic sial- necropsy. Tissue was obtained from necropsies adenitis in the submandibular and minor labial at the Bernhard Baron Institute of Pathology, glands in a series of postmortem subjects. London Hospital, and the University Depart- Waterhouse (1963) has shown that the changes ment of Pathology, Royal Infirmary, Glasgow, observed in the submandibular gland in the between March and June 1967. They were taken postmortem subject reflect the degree of focal from all necropsies on fixed days of the week adenitis present in the parotid and lacrimal excepting a few not obtainable for administrative glands.
    [Show full text]
  • Salivary Glands
    GASTROINTESTINAL SYSTEM [Anatomy and functions of salivary gland] 1 INTRODUCTION Digestive system is made up of gastrointestinal tract (GI tract) or alimentary canal and accessory organs, which help in the process of digestion and absorption. GI tract is a tubular structure extending from the mouth up to anus, with a length of about 30 feet. GI tract is formed by two types of organs: • Primary digestive organs. • Accessory digestive organs 2 Primary Digestive Organs: Primary digestive organs are the organs where actual digestion takes place. Primary digestive organs are: Mouth Pharynx Esophagus Stomach 3 Anatomy and functions of mouth: FUNCTIONAL ANATOMY OF MOUTH: Mouth is otherwise known as oral cavity or buccal cavity. It is formed by cheeks, lips and palate. It encloses the teeth, tongue and salivary glands. Mouth opens anteriorly to the exterior through lips and posteriorly through fauces into the pharynx. Digestive juice present in the mouth is saliva, which is secreted by the salivary glands. 4 ANATOMY OF MOUTH 5 FUNCTIONS OF MOUTH: Primary function of mouth is eating and it has few other important functions also. Functions of mouth include: Ingestion of food materials. Chewing the food and mixing it with saliva. Appreciation of taste of the food. Transfer of food (bolus) to the esophagus by swallowing . Role in speech . Social functions such as smiling and other expressions. 6 SALIVARY GLANDS: The saliva is secreted by three pairs of major (larger) salivary glands and some minor (small) salivary glands. Major glands are: 1. Parotid glands 2. Submaxillary or submandibular glands 3. Sublingual glands. 7 Parotid Glands: Parotid glands are the largest of all salivary glands, situated at the side of the face just below and in front of the ear.
    [Show full text]
  • Characteristics of the Saliva Flow Rates of Minor Salivary Glands in Healthy
    a r c h i v e s o f o r a l b i o l o g y 6 0 ( 2 0 1 5 ) 3 8 5 – 3 9 2 Available online at www.sciencedirect.com ScienceDirect journal homepage: http://www.elsevier.com/locate/aob Characteristics of the saliva flow rates of minor salivary glands in healthy people a b a c a, Zhen Wang , Ming-Ming Shen , Xiao-Jing Liu , Yan Si , Guang-Yan Yu * a Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, 100081, Beijing, PR China b Department of Oral and Maxillofacial Surgery, School of Stomatology, the Second Hospital of Hebei Medical University, 050000, Shijiazhuang, PR China c Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, 100081, Beijing, PR China a r t i c l e i n f o a b s t r a c t Article history: Objectives: To investigate the normal range and characteristics of saliva secretion in the Accepted 23 November 2014 minor salivary glands (MSGs). Design: The flow rates of MSGs were measured in 4 anatomical locations of oral mucosa, and Keywords: the relationship between MSG flow rates and whole saliva flow rates were assessed in 300 healthy subjects stratified by age and sex. An additional 30 young females were further Minor salivary gland Saliva evaluated for flow symmetry, effects of stimulation, circadian effects in MSGs, and the relationship with the flow rates of major salivary glands. Saliva secretion Results: (1) The mean saliva flow rates were 2.10 Æ 0.66 (lower labial glands), 2.14 Æ 0.62 Saliva flow rate 2 (upper labial glands), 2.88 Æ 0.72 (buccal glands) and 2.15 Æ 0.51 (palatal glands) ml/min/cm , Salivary gland respectively.
    [Show full text]
  • Buccal Fat Pad – a Simple, Underutilised Flap E
    SAJS Case Report Buccal fat pad – a simple, underutilised flap E. Meyer, M.B. Ch.B., F.C.O.R.L. (S.A.) S. J. R. Liebenberg, M.B. Ch.B., M.R.C.S. (Ed.), F.C.O.R.L. (S.A.) J. J. Fagan, M.B. Ch.B., M.Med., F.C.O.R.L. (S.A.) Division of Otolaryngology, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital Summary The pedicled buccal fat pad is a reliable flap for the repair of small oral defects. It is durable, easy to harvest, and should be considered in settings where access to free flaps is limited and in cases where previous flaps have failed. We discuss a case in which this flap was used successfully for closure of an oro-antral fistula. The indications, anatomy and techniques of successful harvest are discussed. S Afr J Surg 2012;50(2):47-49. A 57-year-old woman presented in 1998 with a benign minor salivary gland tumour of the hard palate. A wide local excision Fig. 2. Buccal fat pad sutured to cover the oro-antral fistula. of the tumour was performed. The excision margins extended onto the palatal bone, but no bone was excised. The greater palatine artery was ligated and the bone was left to re-epithelialise spontaneously. Two years later, she again had a benign palatal lesion which was excised. The surgery resulted in an oro-antral fistula. In 2007 she was symptomatic, with all fluids coming through her nose when drinking. A local gingival mucosal rotational flap was done without success.
    [Show full text]
  • Distribution and Roles of Substance P in Human Parotid Duct
    IJAE Vol. 121, n. 3: 219-225, 2016 ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY Research article - Histology and cell biology Distribution and roles of substance P in human parotid duct Kaori Amano1,*, Osamu Amano2, George Matsumura3, Kazuyuki Shimada4 1,3Department of Anatomy, Kyorin University School of Medicine; 2Department of Anatomy, Meikai University School of Dentistry; 4Kagoshima University Abstract Sialadenitis occurs with greatest frequency in the parotid glands because infection and inflam- mation arise easily from the oral cavity. Since patients often experience severe swelling and pain during inflammation, the distribution of sensory nerves in these ducts may have clini- cal significance. We used antibodies to the known neuropeptide substance P and to tyrosine hydroxylase - a marker of adrenergic fibres - to observe their distribution and gain insight on their functional role in adult human parotid duct. After excising the parotid duct along with the gland, specimens were divided into three regions: the tract adjacent to the parotid gland, the route along the anterior surface of the masseter, and the area where the duct penetrates the buc- cinator muscle and opens into the oral cavity. Specimens were prepared and examined under a fluorescence microscope following immunostaining. Substance P positivity was observed in all three regions of the duct, whereas tyrosine hydroxylase was distributed mainly in the vas- cular walls and surrounding areas. The distribution of substance P candidates this molecule to assist in tissue defense in conjunction with the blood and lymph vessels of this area. Tyrosine hydroxylase in the blood vessel wall likely contributes to regulation of blood flow in concert with substance P positive nerves surrounding the blood vessels.
    [Show full text]
  • Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases
    International Scholarly Research Network ISRN Dentistry Volume 2011, Article ID 457567, 6 pages doi:10.5402/2011/457567 Case Report Cheilitis Glandularis: Two Case Reports of Asian-Japanese Men and Literature Review of Japanese Cases Toru Yanagawa,1 Akira Yamaguchi,2 Hiroyuki Harada,3 Kenji Yamagata,1 Naomi Ishibashi,1 Masayuki Noguchi,4 Kojiro Onizawa,1 and Hiroki Bukawa1 1 Department of Oral and Maxillofacial Surgery, Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan 2 Section of Oral Pathology, Division of Oral Health Sciences, Department of Oral Restitution, Graduate School Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan 3 Section of Oral and Maxillofacial Surgery, Division of Oral Health Sciences, Department of Oral Restitution, Graduate School Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan 4 Department of Pathology, Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan Correspondence should be addressed to Toru Yanagawa, [email protected] Received 25 October 2010; Accepted 5 December 2010 Academic Editor: G. L. Lodi Copyright © 2011 Toru Yanagawa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cheilitis glandularis (CG) is a rare disorder characterized by swelling of the lip with hyperplasia of the labial salivary glands. CG is most frequently encountered in the lower lip, in middle-aged to older Caucasian men; however Asian cases were rarely reported.
    [Show full text]
  • Atlas of the Facial Nerve and Related Structures
    Rhoton Yoshioka Atlas of the Facial Nerve Unique Atlas Opens Window and Related Structures Into Facial Nerve Anatomy… Atlas of the Facial Nerve and Related Structures and Related Nerve Facial of the Atlas “His meticulous methods of anatomical dissection and microsurgical techniques helped transform the primitive specialty of neurosurgery into the magnificent surgical discipline that it is today.”— Nobutaka Yoshioka American Association of Neurological Surgeons. Albert L. Rhoton, Jr. Nobutaka Yoshioka, MD, PhD and Albert L. Rhoton, Jr., MD have created an anatomical atlas of astounding precision. An unparalleled teaching tool, this atlas opens a unique window into the anatomical intricacies of complex facial nerves and related structures. An internationally renowned author, educator, brain anatomist, and neurosurgeon, Dr. Rhoton is regarded by colleagues as one of the fathers of modern microscopic neurosurgery. Dr. Yoshioka, an esteemed craniofacial reconstructive surgeon in Japan, mastered this precise dissection technique while undertaking a fellowship at Dr. Rhoton’s microanatomy lab, writing in the preface that within such precision images lies potential for surgical innovation. Special Features • Exquisite color photographs, prepared from carefully dissected latex injected cadavers, reveal anatomy layer by layer with remarkable detail and clarity • An added highlight, 3-D versions of these extraordinary images, are available online in the Thieme MediaCenter • Major sections include intracranial region and skull, upper facial and midfacial region, and lower facial and posterolateral neck region Organized by region, each layered dissection elucidates specific nerves and structures with pinpoint accuracy, providing the clinician with in-depth anatomical insights. Precise clinical explanations accompany each photograph. In tandem, the images and text provide an excellent foundation for understanding the nerves and structures impacted by neurosurgical-related pathologies as well as other conditions and injuries.
    [Show full text]
  • A Guide to Salivary Gland Disorders the Salivary Glands May Be Affected by a Wide Range of Neoplastic and Inflammatory
    MedicineToday PEER REVIEWED ARTICLE CPD 1 POINT A guide to salivary gland disorders The salivary glands may be affected by a wide range of neoplastic and inflammatory disorders. This article reviews the common salivary gland disorders encountered in general practice. RON BOVA The salivary glands include the parotid glands, examination are often adequate to recognise and MB BS, MS, FRACS submandibular glands and sublingual glands differentiate many of these conditions. A wide (Figure 1). There are also hundreds of minor sali- array of benign and malignant neoplasms may also Dr Bova is an ENT, Head and vary glands located in the mucosa of the hard and affect the salivary glands and a neoplasia should Neck Surgeon, St Vincent’s soft palate, oral cavity, lips, tongue and oro - always be considered when assessing a salivary Hospital, Sydney, NSW. pharynx. The parotid gland lies in the preauricular gland mass. region and extends inferiorly over the angle of the mandible. The parotid duct courses anteriorly Inflammatory disorders from the parotid gland and enters the mouth Acute sialadenitis through the buccal mucosa adjacent to the second Acute inflammation of the salivary glands is usu- upper molar tooth. The submandibular gland lies ally of viral or bacterial origin. Mumps is the most in the submandibular triangle and its duct passes common causative viral illness, typically affecting anteriorly along the floor of the mouth to enter the parotid glands bilaterally. Children are most adjacent to the frenulum of the tongue. The sub- often affected, with peak incidence occurring at lingual glands are small glands that lie just beneath approximately 4 to 6 years of age.
    [Show full text]