Studies in Astereognosis. Summary of the Results
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Stroke and Aphasia Aphasia Is a Language Disorder That Affects the Ability to Communicate
Recovery Primary motor cortex Primary sensory cortex let’s talk about Broca’s area Stroke and Aphasia Aphasia is a language disorder that affects the ability to communicate. It’s most often caused by strokes that occur in areas of the brain that control Primary auditory area Primary speech and language. Wernicke’s area visual cortex Certain areas of the brain (usually in the left side of the brain) influence one’s ability to communicate and understand language. When a stroke occurs in one of these areas, it may result in aphasia. What are the effects of aphasia? sender plissen.” Thousands of alert, intelligent men and Aphasia does not affect intelligence. Stroke survivors women are suddenly plunged into a world of jumbled remain mentally alert, even though their speech may communication because of aphasia. be jumbled, fragmented or impossible to understand. Are there different types of aphasia? Some survivors continue to have: Yes, there are several forms of aphasia. They include: • Trouble speaking, like “getting the words out” • Global aphasia — People with this aphasia may • Trouble finding words be completely unable to speak, name objects, repeat • Problems understanding what others say phrases or follow commands. • Problems with reading, writing or math • Broca’s aphasia — The person knows what they • Inability to process long words and infrequently want to say, but can’t find the right words (can’t get used words the words out). • Wernicke’s aphasia — A person with this aphasia How does it feel to have aphasia? can seldom understand what’s being said or control People with aphasia are often frustrated and confused what they’re saying. -
Abadie's Sign Abadie's Sign Is the Absence Or Diminution of Pain Sensation When Exerting Deep Pressure on the Achilles Tendo
A.qxd 9/29/05 04:02 PM Page 1 A Abadie’s Sign Abadie’s sign is the absence or diminution of pain sensation when exerting deep pressure on the Achilles tendon by squeezing. This is a frequent finding in the tabes dorsalis variant of neurosyphilis (i.e., with dorsal column disease). Cross References Argyll Robertson pupil Abdominal Paradox - see PARADOXICAL BREATHING Abdominal Reflexes Both superficial and deep abdominal reflexes are described, of which the superficial (cutaneous) reflexes are the more commonly tested in clinical practice. A wooden stick or pin is used to scratch the abdomi- nal wall, from the flank to the midline, parallel to the line of the der- matomal strips, in upper (supraumbilical), middle (umbilical), and lower (infraumbilical) areas. The maneuver is best performed at the end of expiration when the abdominal muscles are relaxed, since the reflexes may be lost with muscle tensing; to avoid this, patients should lie supine with their arms by their sides. Superficial abdominal reflexes are lost in a number of circum- stances: normal old age obesity after abdominal surgery after multiple pregnancies in acute abdominal disorders (Rosenbach’s sign). However, absence of all superficial abdominal reflexes may be of localizing value for corticospinal pathway damage (upper motor neu- rone lesions) above T6. Lesions at or below T10 lead to selective loss of the lower reflexes with the upper and middle reflexes intact, in which case Beevor’s sign may also be present. All abdominal reflexes are preserved with lesions below T12. Abdominal reflexes are said to be lost early in multiple sclerosis, but late in motor neurone disease, an observation of possible clinical use, particularly when differentiating the primary lateral sclerosis vari- ant of motor neurone disease from multiple sclerosis. -
• Classifications of Aphasia Expressive Vs. Receptive Fluent Vs
12/7/2018 APHASIA Aphasia is an acquired communication disorder that impairs a person’s ability to process LANGUAGE, but DOES NOT AFFECT intelligence. Aphasia impairs the ability to speak and understand others. -National Aphasia Association LANGUAGE Language is a system of communication that uses symbolism. K L U $ + M – Phonemes: perceptually distinct unit of sounds Words: sounds combined & given meaning Sentences: combination of syntax (rules) and semantics (meaning). • CLASSIFICATIONS OF APHASIA EXPRESSIVE VS. RECEPTIVE FLUENT VS. NON- FLUENT 1 12/7/2018 -NATIONAL APHASIA ASSOCIATION -COURTESY OF MY-MS.ORG MCA DISTRIBUTION -SLIDESHARE.NET 2 12/7/2018 BROCA’S APHASIA * short utterances * limited vocabulary * halting, effortful speech *mild comprehension deficits Lesion * Inferior frontal gyrus Choose Sentence Speech Coordinate Speak Idea Words Structure Sounds Articulate Pragmatics Muscles Fluently (Semantics) (Syntax) (Phonology) SAMPLE OF BROCA’S THERAPY FROM TACTUS THERAPY 3 12/7/2018 WERNICKE’S APHASIA • Comprehension is poor (auditory & reading) • Fluent, intact prosody • Logorrhea, press of speech • Neologisms, Paraphasias • Lack of awareness Lesion Temporo-Parietal, Posterior section of the superior temporal gyrus near the auditory cortex Auditory Preparation Attach Input Perception Recognition Phonological For Meaning Analysis Output WERNICKE’S APHASIA FROM TACTUS THERAPY 4 12/7/2018 GLOBAL APHASIA * severe language deficit * responds to personally relevant language * responds to non-verbal cues * some automatic speech Lesion -
THE SYNDROMES of the ARTERIES of the BRAIN and SPINAL CORD Part 1 by LESLIE G
65 Postgrad Med J: first published as 10.1136/pgmj.29.328.65 on 1 February 1953. Downloaded from THE SYNDROMES OF THE ARTERIES OF THE BRAIN AND SPINAL CORD Part 1 By LESLIE G. KILOH, M.D., M.R.C.P., D.P.M. First Assistant in the Joint Department of Psychological Medicine, Royal Victoria Infirmary and University of Durham Introduction general circulatory efficiency at the time of the Little interest is shown at present in the syn- catastrophe is of the greatest importance. An dromes of the arteries of the brain and spinal cord, occlusion, producing little effect in the presence of and this perhaps is related to the tendency to a normal blood pressure, may cause widespread minimize the importance of cerebral localization. pathological changes if hypotension co-exists. Yet these syndromes are far from being fully A marked discrepancy has been noted between elucidated and understood. It must be admitted the effects of ligation and of spontaneous throm- that in many cases precise localization is often of bosis of an artery. The former seldom produces little more than academic interest and ill effects whilst the latter frequently determines provides Protected by copyright. nothing but a measure of personal satisfaction to infarction. This is probably due to the tendency the physician. But it is worth recalling that the of a spontaneous thrombus to extend along the detailed study of the distribution of the bronchi affected vessel, sealing its branches and blocking and of the pathological anatomy of congenital its collateral circulation, and to the fact that the abnormalities of the heart, was similarly neglected arterial disease is so often generalized. -
Number Reading in Pure Alexiaâ
Neuropsychologia 49 (2011) 2283–2298 Contents lists available at ScienceDirect Neuropsychologia jo urnal homepage: www.elsevier.com/locate/neuropsychologia Reviews and perspectives Number reading in pure alexia—A review a,∗ b Randi Starrfelt , Marlene Behrmann a Center for Visual Cognition, Department of Psychology, Copenhagen University, O. Farimagsgade 2A, DK-1353 Copenhagen K, Denmark b Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA a r t i c l e i n f o a b s t r a c t Article history: It is commonly assumed that number reading can be intact in patients with pure alexia, and that this Received 25 October 2010 dissociation between letter/word recognition and number reading strongly constrains theories of visual Received in revised form 31 March 2011 word processing. A truly selective deficit in letter/word processing would strongly support the hypothesis Accepted 22 April 2011 that there is a specialized system or area dedicated to the processing of written words. To date, however, Available online 4 May 2011 there has not been a systematic review of studies investigating number reading in pure alexia and so the status of this assumed dissociation is unclear. We review the literature on pure alexia from 1892 to Keywords: 2010, and find no well-documented classical dissociation between intact number reading and impaired Pure alexia letter identification in a patient with pure alexia. A few studies report strong dissociations, with number Alexia without agraphia reading less impaired than letter reading, but when we apply rigorous statistical criteria to evaluate Letter-by-letter reading Visual recognition these dissociations, the difference in performance across domains is not statistically significant. -
High-Yield Neuroanatomy
LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page i Aptara Inc. High-Yield TM Neuroanatomy FOURTH EDITION LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page ii Aptara Inc. LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page iii Aptara Inc. High-Yield TM Neuroanatomy FOURTH EDITION James D. Fix, PhD Professor Emeritus of Anatomy Marshall University School of Medicine Huntington, West Virginia With Contributions by Jennifer K. Brueckner, PhD Associate Professor Assistant Dean for Student Affairs Department of Anatomy and Neurobiology University of Kentucky College of Medicine Lexington, Kentucky LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page iv Aptara Inc. Acquisitions Editor: Crystal Taylor Managing Editor: Kelley Squazzo Marketing Manager: Emilie Moyer Designer: Terry Mallon Compositor: Aptara Fourth Edition Copyright © 2009, 2005, 2000, 1995 Lippincott Williams & Wilkins, a Wolters Kluwer business. 351 West Camden Street 530 Walnut Street Baltimore, MD 21201 Philadelphia, PA 19106 Printed in the United States of America. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Lippincott Williams & Wilkins at 530 Walnut Street, Philadelphia, PA 19106, via email at [email protected], or via website at http://www.lww.com (products and services). -
Journal of Neurological Disorders DOI: 10.4172/2329-6895.1000309 ISSN: 2329-6895
olog eur ica N l D f i o s l o a r n d r e u r s o J Lee, et al., J Neurol Disord 2016, 4:7 Journal of Neurological Disorders DOI: 10.4172/2329-6895.1000309 ISSN: 2329-6895 Case Report Open Access Two Cases with Cerebral Infarction in the Left Middle Frontal Lobe Presented as Gerstmann's Syndrome Eun-Ju Lee, Hye-Young Shin, Young Noh, Ki-Hyung Park, Hyeon-Mi Park, Yeong-Bae Lee, Dong-Jin Shin, Young Hee Sung and Dong Hoon Shin* Department of Neurology, Gil Hospital, Gachon University Gil Medical Center, Incheon, South Korea *Corresponding author: Dong Hoon Shin, Department of Neurology, Gil Hospital, Gachon University Gil Medical Center, South Korea, Tel: +82-32-460-3346; Fax: +83-32-460-3344; E-mail: [email protected] Rec date: Oct 08, 2016, Acc date: Oct 18, 2016, Pub date: Oct 22, 2016 Copyright: © 2016 Lee, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Gerstmann's syndrome is a neuropsychological disorder characterized by four symptoms, namely, acalculia, finger agnosia, left-right disorientation, and agraphia suggesting the presence of a lesion in the inferior parietal lobule of the dominant hemisphere, especially at the angular gyrus. Several descriptions of Gerstmann's syndrome have been reported in associated with a lesion to the left frontal lobe, but none of these reports fulfilled the full tetrad of diagnostic criteria. -
26 Aphasia, Memory Loss, Hemispatial Neglect, Frontal Syndromes and Other Cerebral Disorders - - 8/4/17 12:21 PM )
1 Aphasia, Memory Loss, 26 Hemispatial Neglect, Frontal Syndromes and Other Cerebral Disorders M.-Marsel Mesulam CHAPTER The cerebral cortex of the human brain contains ~20 billion neurons spread over an area of 2.5 m2. The primary sensory and motor areas constitute 10% of the cerebral cortex. The rest is subsumed by modality- 26 selective, heteromodal, paralimbic, and limbic areas collectively known as the association cortex (Fig. 26-1). The association cortex mediates the Aphasia, Memory Hemispatial Neglect, Frontal Syndromes and Other Cerebral Disorders Loss, integrative processes that subserve cognition, emotion, and comport- ment. A systematic testing of these mental functions is necessary for the effective clinical assessment of the association cortex and its dis- eases. According to current thinking, there are no centers for “hearing words,” “perceiving space,” or “storing memories.” Cognitive and behavioral functions (domains) are coordinated by intersecting large-s- cale neural networks that contain interconnected cortical and subcortical components. Five anatomically defined large-scale networks are most relevant to clinical practice: (1) a perisylvian network for language, (2) a parietofrontal network for spatial orientation, (3) an occipitotemporal network for face and object recognition, (4) a limbic network for explicit episodic memory, and (5) a prefrontal network for the executive con- trol of cognition and comportment. Investigations based on functional imaging have also identified a default mode network, which becomes activated when the person is not engaged in a specific task requiring attention to external events. The clinical consequences of damage to this network are not yet fully defined. THE LEFT PERISYLVIAN NETWORK FOR LANGUAGE AND APHASIAS The production and comprehension of words and sentences is depen- FIGURE 26-1 Lateral (top) and medial (bottom) views of the cerebral dent on the integrity of a distributed network located along the peri- hemispheres. -
THE SYNDROMES of the ARTERIES of the BRAIN AND, SPINAL CORD Part II by LESLIE G
I19 Postgrad Med J: first published as 10.1136/pgmj.29.329.119 on 1 March 1953. Downloaded from - N/ THE SYNDROMES OF THE ARTERIES OF THE BRAIN AND, SPINAL CORD Part II By LESLIE G. KILOH, M.D., M.R.C.P., D.P.M. First Assistant in the Joint Department of Psychological Medicine, Royal Victoria Infirmary and University of Durham The Vertebral Artery (See also Cabot, I937; Pines and Gilensky, Each vertebral artery enters the foramen 1930.) magnum in front of the roots of the hypoglossal nerve, inclines forwards and medially to the The Posterior Inferior Cerebellar Artery anterior aspect of the medulla oblongata and unites The posterior inferior cerebellar artery arises with its fellow at the lower border of the pons to from the vertebral artery at the level of the lower form the basilar artery. border of the inferior olive and winds round the The posterior inferior cerebellar and the medulla oblongata between the roots of the hypo- Protected by copyright. anterior spinal arteries are its principal branches glossal nerve. It passes rostrally behind the root- and it sometimes gives off the posterior spinal lets of the vagus and glossopharyngeal nerves to artery. A few small branches are supplied directly the lower border of the pons, bends backwards and to the medulla oblongata. These are in line below caudally along the inferolateral boundary of the with similar branches of the anterior spinal artery fourth ventricle and finally turns laterally into the and above with the paramedian branches of the vallecula. basilar artery. Branches: From the trunk of the artery, In some cases of apparently typical throm- twigs enter the lateral aspect of the medulla bosis of the posterior inferior cerebellar artery, oblongata and supply the region bounded ventrally post-mortem examination has demonstrated oc- by the inferior olive and medially by the hypo- clusion of the entire vertebral artery (e.g., Diggle glossal nucleus-including the nucleus ambiguus, and Stcpford, 1935). -
Definition of Stroke/Brain Attack
Definition of Stroke/Brain Attack Stroke II: • A syndrome caused by disruption in the flow of Diagnosis, Evaluation, and Prevention blood to part of the brain due to either: – occlusion of a blood vessel • ischemic stroke Lenore N. Joseph, MD – rupture of a blood vessel Neurology Service Chief, McGuire VAMC • hemorrhagic stroke Assistant Professor of Neurology • The interruption in blood flow deprives the brain VCU Health System of nutrients and oxygen resulting in injury to cells Medical College of Virginia in the affected vascular territory of the brain 1 2 Stroke: The Problem Stroke: The Problem • Third leading cause of death in US • Among 6 month or longer survivors: – after heart disease and cancer – 48% have a hemiparesis • 740,000 new strokes each year – 22% cannot walk • 4.5 million stroke survivors – 24-53% report complete or partial • Leading cause of disability in adults in US dependence for activities • $45.5 billion per year in the USA – 12-18% are aphasic • 1 of 6 Americans will be affected – 32% are clinically depressed – only 10% fully recover 3 4 Symptoms of Brain Attack: Symptoms of Brain Attack: Teach your patients! Teach your patients! • Sudden weakness, paralysis, or numbness of: • Sudden unexplained dizziness –face – especially when associated with other – arm and the leg on one or both sides of the neurologic symptoms body – unsteadiness • Sudden loss of speech, or difficulty speaking or – sudden falls understanding speech • Sudden severe headache and/or loss of • Sudden dimness or loss of vision consciousness – -
High-Yield Neuroanatomy, FOURTH EDITION
LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page i Aptara Inc. High-Yield TM Neuroanatomy FOURTH EDITION LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page ii Aptara Inc. LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page iii Aptara Inc. High-Yield TM Neuroanatomy FOURTH EDITION James D. Fix, PhD Professor Emeritus of Anatomy Marshall University School of Medicine Huntington, West Virginia With Contributions by Jennifer K. Brueckner, PhD Associate Professor Assistant Dean for Student Affairs Department of Anatomy and Neurobiology University of Kentucky College of Medicine Lexington, Kentucky LWBK110-3895G-FM[i-xviii].qxd 8/14/08 5:57 AM Page iv Aptara Inc. Acquisitions Editor: Crystal Taylor Managing Editor: Kelley Squazzo Marketing Manager: Emilie Moyer Designer: Terry Mallon Compositor: Aptara Fourth Edition Copyright © 2009, 2005, 2000, 1995 Lippincott Williams & Wilkins, a Wolters Kluwer business. 351 West Camden Street 530 Walnut Street Baltimore, MD 21201 Philadelphia, PA 19106 Printed in the United States of America. All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Lippincott Williams & Wilkins at 530 Walnut Street, Philadelphia, PA 19106, via email at [email protected], or via website at http://www.lww.com (products and services). -
Aphasia Accessible Information Guidelines
stroke.org.uk Accessible Information Guidelines Making information accessible for people with aphasia We believe in life after stroke. That’s why we support stroke survivors to make the best recovery they can. It’s why we campaign for better stroke care. And it’s why we fund research into new treatments and ways of preventing stroke. We’re here for you. If you’d like to know more please get in touch. Stroke Helpline: 0303 3033 100 Website: stroke.org.uk Email: [email protected] Textphone: 18001 0303 3033 100 © Stroke Association, July 2012 ISBN 978-0-901548-66-5 All rights reserved. No part of this publication may be reproduced or transmitted, in any form or by any means, electronic, photocopying or otherwise without prior permission of the publishers. NHS workers and teachers may make photocopies for education purposes only, provided that no charge or profit is made for any course or event for which they are used. Published by the Stroke Association Stroke Association House 240 City Road London EC1V 2PR stroke.org.uk Stroke Association is a Company Limited by Guarantee, registered in England and Wales (No 61274). Registered office: Stroke Association House, 240 City Road, London EC1V 2PR. Registered as a Charity in England and Wales (No 211015) and in Scotland (SC037789). Also registered in Northern Ireland (XT33805) Isle of Man (No 945) and Jersey (NPO 369). 2 Stroke Association Contents Authors and acknowledgements 4 Introduction 5 The Five Steps 9 Step 1: A short message 10 Step 2: Clear sentences 11 Step 3: Easy words 14 Step 4: Good layout 15 Step 5: Make a set 21 Checklist 23 Word-processing advice 24 Further Reading 28 Notes 30 Stroke Association is a Company Limited by Guarantee, registered in England and Wales (No 61274).