A Report to the President U.S
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I Have Been Working on a Book, Stand-Ins, on The
Workshop Participants: I have been working on a book, Stand-Ins, on the causes and consequences of temporary leadership in government, business, and religion, which is aimed at a more general audience. Given recent events, I have returned to more traditional scholarship to explore some of the issues involving temporary leadership (and the lack thereof) in federal agencies, among other topics. This paper is brand new, incomplete, and unpolished. Given its length, I would recommend reading the Introduction (pp.1-5), Scope of Actings (pp.13-27), and Statutory Questions (pp.33-42). I look forward to your reactions and suggestions for improvement. AJO Actings Anne Joseph O’Connell Stanford Law School April 1, 2019 Please do not cite or distribute beyond the workshop without permission. I. Introduction Stand-in leaders do not usually command much attention. They step up in moments of need to keep organizations running. The stereotypical interim leader is therefore a caretaker—in place to maintain stability; not to implement major changes. But not all interim leaders are caretakers. Some are auditioning for the permanent job. And a few are there to shake up the organization—so-called “fixers”. The scope of temporary leadership is vast—after all, traditional leaders are transitory, and selection procedures for more permanent leaders take time. On the public side, there are interim leaders in all branches of the federal government. In Congress, there are appointed senators, chosen by their state’s governor to fill in for an elected senator who has died or resigned, perhaps in disgrace or perhaps to take a different job. -
PI3K Inhibitors in Cancer: Clinical Implications and Adverse Effects
International Journal of Molecular Sciences Review PI3K Inhibitors in Cancer: Clinical Implications and Adverse Effects Rosalin Mishra , Hima Patel, Samar Alanazi , Mary Kate Kilroy and Joan T. Garrett * Department of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267-0514, USA; [email protected] (R.M.); [email protected] (H.P.); [email protected] (S.A.); [email protected] (M.K.K.) * Correspondence: [email protected]; Tel.: +1-513-558-0741; Fax: +1-513-558-4372 Abstract: The phospatidylinositol-3 kinase (PI3K) pathway is a crucial intracellular signaling pathway which is mutated or amplified in a wide variety of cancers including breast, gastric, ovarian, colorectal, prostate, glioblastoma and endometrial cancers. PI3K signaling plays an important role in cancer cell survival, angiogenesis and metastasis, making it a promising therapeutic target. There are several ongoing and completed clinical trials involving PI3K inhibitors (pan, isoform-specific and dual PI3K/mTOR) with the goal to find efficient PI3K inhibitors that could overcome resistance to current therapies. This review focuses on the current landscape of various PI3K inhibitors either as monotherapy or in combination therapies and the treatment outcomes involved in various phases of clinical trials in different cancer types. There is a discussion of the drug-related toxicities, challenges associated with these PI3K inhibitors and the adverse events leading to treatment failure. In addition, novel PI3K drugs that have potential to be translated in the clinic are highlighted. Keywords: cancer; PIK3CA; resistance; PI3K inhibitors Citation: Mishra, R.; Patel, H.; Alanazi, S.; Kilroy, M.K.; Garrett, J.T. -
Greg J Sheehan, FWS Principal Deputy Director
Greg J Sheehan, FWS Principal Deputy Director Tue Jun 6, 2017 2:45pm FWS weekly check in meeting Video call: (b) (5), (b) (6) Where: AS/FWP Conference Room -- 3144 Calendar: Maureen Foster Created by: Tasha Robbins Who: Thomas Irwin, Charisa Morris, Maureen Foster, Richard Goeken, GregSheehan, Wendy Fink, Stephen Guertin, Catherine Gulac, Jason Larrabee,Tasha Robbins, Aurelia Skipwith, Marshall Critchfield, Heather Swift,Jim Kurth, Todd Willens, Roslyn Sellars, Zachariah Gambill, PegRomanik, Barbara Wainman 3pm *FWS weekly check in meeting Video call: (b) (5), (b) (6) Where: AS/FWP Conference Room -- 3144 Calendar: Greg Sheehan Created by: Roslyn Sellars Wed Jun 7, 2017 1pm OIG monthly status update meeting/conference call (Jim, Steve, Kathy Garrity, Keith Toomey, Charisa) Room 3357 Video call: (b) (5), (b) (6) Where: Dial: (b) (5) , Code: (b) (5) Calendar: Jim Kurth Created by: Roslyn Sellars Who: Casey Hammond, Stephen Guertin, Katherine Garrity, Jim Kurth, GregSheehan, Charisa Morris, Keith Toomey 2:30pm [Asst Directors/Regional Directors Only-No Deputies or Actings] - Weekly Directorate VTC: Transition Check-In--Room 3038 Video call: (b) (5), (b) (6) Calendar: Jim Kurth Created by: Thomas Irwin Who: [email protected], Tom Melius, [email protected], WandaCantrell, Edward Grace, [email protected], Henry Schlitzer,Pamela Michalegko, Kenneth Taylor, Benjamin Tuggle, Brian Bloodsworth,Robyn Thorson, Gary Frazer, Michael Gale, Jim Kurth, Charisa Morris,Paul Rauch, Denise Thompson, Seth Mott, Cynthia Martinez,cynthia_dohner@fws -
INTERIOR Energy Companies Paid Bernhardt More Than $80K Last Year
INTERIOR Energy companies paid Bernhardt more than $80K last year Corbin Hiar, E&E News reporter Published: Thursday, May 11, 2017 David Bernhardt filed documents ahead of his confirmation hearing to be Interior deputy secretary that said he will recuse himself for a year from issues involving companies he had lobbied for. Photo courtesy of Brownstein Hyatt Farber Schreck LLP. Interior deputy secretary nominee David Bernhardt earned at least $80,000 last year working for a host of energy and environmental interests, disclosure forms show. He agreed to recuse himself for one year from matters involving any of the companies as well as other former clients of his or his law firm, Brownstein Hyatt Farber Schreck LLP. The documents Bernhardt filed in order to advance through the confirmation process were signed off on earlier this week by the Interior Department's top ethics official. Bernhardt's financial disclosure report was filed with the independent Office of Government Ethics on March 6, more than a month before the White House formally nominated him for Interior's second-highest post (Greenwire, April 28). The disclosures show Bernhardt made more than $1.1 million last year from Brownstein Hyatt, where he is a partner, and a holding company of the law firm. The disclosure report lists the following clients as paying him at least $5,000 for his legal services in 2016: Targa Resources Co. LLC, Noble Energy Co. LLC, NRG Energy Inc., Sempra Energy, Lafarge North America - Western Region, Safari Club International Foundation, Active Network LLC, Statoil Gulf Services LLC, Cobalt International Energy, Rosemont Copper Co., Independent Petroleum Association of America, Taylor Energy Co. -
Eastern Progress 1992-1993 Eastern Progress
Eastern Kentucky University Encompass Eastern Progress 1992-1993 Eastern Progress 3-11-1993 Eastern Progress - 11 Mar 1993 Eastern Kentucky University Follow this and additional works at: http://encompass.eku.edu/progress_1992-93 Recommended Citation Eastern Kentucky University, "Eastern Progress - 11 Mar 1993" (1993). Eastern Progress 1992-1993. Paper 24. http://encompass.eku.edu/progress_1992-93/24 This News Article is brought to you for free and open access by the Eastern Progress at Encompass. It has been accepted for inclusion in Eastern Progress 1992-1993 by an authorized administrator of Encompass. For more information, please contact [email protected]. ACCENT ACTIVITIES WEEKEND FORECAST Buffalo wings FRIDAY: Chance of snow Much to 'Fear' On the road high in the 30* See who can boast L. Ron Hubbard's new Bruises, taunts part SATURDAY: Flurries, high to be the best in town In the 30s thriller gives chills of lacrosse lore SUNDAY: cold, high in Page A-5 Page A-7 Page A-9 the 30s THE EASTERN PROGRESS Vol. 71/No. 24 12 pages March 11, 1993 Student publication ot Eastern Kentucky University, Richmond. Ky. 40475 © The Eastern Progress, 1993 1993 STD case numbers decrease on campus Students By Mark White it can kill me. You really can't tell News editor SAFE SEX who you can get it from by having teach AIDS Myth or sex." EASTERN STUDENTS AND STD'S According to figures from the Although student health services offers testing for many sexually trans- American College Health Association, M The Progress surveyed 177 students about sexually prevention one out of every 500 students are HIV mitted diseases, it does not offer test- positive. -
The People Shaping the Trump Administration
The People Shaping the Trump Administration Despite Running on a Pledge to ‘Drain the Swamp’ and Crack Down on Special Interests, Donald Trump Has Filled His Transition Team With Lobbyists and Others With Potential Conflicts November 16, 2016 – Donald Trump rode to the White House by raging about alleged rampant corruption in Washington and pledging to “drain the swamp.” Each of the five points in the ethics platform he issued in October focused on diminishing the influence of lobbyists.1 These included a promise to impose a five-year ban on former executive branch officials lobbying the federal government. Trump further promised to crack down on special interest-influence by expanding the definition of lobbyist to include consultants and others who trade on inside government information and expertise.2 But Trump’s nascent transition team, which will shape his administration, is swarming with lobbyists and other special interests. Many of the lobbyists are working for the transition on areas for which they currently are lobbying the federal government. Meanwhile, many of those who aren’t lobbyists appear to have potential conflicts of interest. Vice president-elect Mike Pence reportedly said on November 15 that the transition team would be purged of lobbyists, but the transition team has not made the point official.3 Even if true, that remedy would not address cases such as a defense contractor working on defense interests, or a lawyer for health care interests working on health care reform. Here are brief summaries of individuals who have been reported in the media as overseeing agencies or policies for Trump’s transition team. -
New Mexico Meadow Jumping Mouse; Final Rule, 81 Fed
Case 1:18-cv-01138-JB-JFR Document 43 Filed 10/13/20 Page 1 of 241 IN THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF NEW MEXICO NORTHERN NEW MEXICO STOCKMAN’S ASSOCIATION and OTERO COUNTY CATTLEMAN’S ASSOCIATION, Plaintiffs, vs. No. CIV 18-1138 JB\JFR UNITED STATES FISH & WILDLIFE SERVICE and GREG SHEEHAN, Principal Deputy Director & Acting Director of the United States Fish & Wildlife Service, in his official capacity, Defendants, and CENTER FOR BIOLOGICAL DIVERSITY and WILDEARTH GUARDIANS, Intervenors. MEMORANDUM OPINION AND ORDER THIS MATTER comes before the Court on: (i) the Plaintiffs’ Opening Brief in Support of Petition for Review, filed August 8, 2019 (Doc. 26)(“Petition”); (ii) Petitioners’ Brief on Remedy, filed December 6, 2019 (Doc. 40)(“P. Remedy Brief”); (iii) Federal Respondents’ Brief on Remedy, filed December 6, 2019 (Doc. 41)(“D. Remedy Brief”); and (iv) Respondent- Intervenors’ Brief on Remedy, filed December 6, 2019 (Doc. 42)(“I. Remedy Brief”). The Court held a hearing on October 31, 2019. The primary issues are: (i) whether Plaintiffs Northern NM Stockman’s Association (“Northern NM Stockman’s Association”) and Otero Cattleman’s Association (“Otero Cattleman’s Association”)(collectively, “the Stockman’s Associations”) suffer economic injury to establish associational standing under Article III of the Constitution of the United States of America to challenge the decision made by Defendants United States Fish & Wildlife Service and its Principal Deputy director and acting director, Greg Sheehan (collectively, “Fish & Wildlife”), to designate land on which members of the Stockman’s Associations graze cattle as critical habitat designation1 (“the designation”) for the New Mexico Meadow Jumping Mouse (“Jumping Mouse”); (ii) whether Fish & Wildlife’s use of the “incremental effects” 1The Endangered Species Act requires Fish & Wildlife to designate “critical habitat” for all species that Fish & Wildlife lists as threatened or endangered. -
Monique Jannette Artist, Paralympian, and Former Civil Rights Lawyer
Texas Disability History Collection, University of Texas at Arlington Monique Jannette Artist, Paralympian, and former Civil Rights Lawyer Interview conducted by Mark Harris In 2016 in Dallas, Texas Disability Studies Minor Special Collections and Archives University of Texas at Arlington Copyright © 2016 by University of Texas at Arlington Libraries Biography Monique Jannette was born September 23, 1962 and graduated from Warren Travis White High School in Dallas, Texas, earned a Bachelor’s of Arts degree in Geology from the University of Texas at Arlington in 1987, and her Law Degree from Southern Methodist University in 1992. While in middle school and high school, she became interested in science and competitive diving. Jannette exceled at diving and traveled throughout the United States and other countries with diving teams. She earned a full scholarship to Southern Methodist University (SMU), but due to an accident shortly after graduation from high school in 1980, she became paraplegic. Starting in 1981, Jannette attended the University of Texas at Arlington (UTA), where she studied geology and participated in adaptive track and field under the direction of Jim Hayes. While attending UTA, she was selected to the 1988 U.S. Paralympic Track and Field team, and Table Tennis team in Seoul, South Korea. In 1992 she was selected again to compete with the U.S. Paralympic Team in Barcelona, Spain. Upon graduating from UTA, Jannette went back to SMU to study law. During her time there she collaborated with architects to make SMU more accessible to people with disabilities. After graduating law school, she and a partner began to practice civil rights law, helping the communities and business in and around the Dallas area. -
The Executive Branch's Limited Authority To
GW Law Faculty Publications & Other Works Faculty Scholarship 2020 The Rocky Road to Energy Dominance: The Executive Branch’s Limited Authority to Modify and Revoke Withdrawals of Federal Lands from Mineral Production Robert L. Glicksman Hillary M. Hoffman Follow this and additional works at: https://scholarship.law.gwu.edu/faculty_publications Part of the Law Commons The Rocky Road to Energy Dominance: The Executive Branch’s Limited Authority to Modify and Revoke Withdrawals of Federal Lands from Mineral Production Hillary M. Hoffmann* & Robert L. Glicksman** 33 GEO. J. ENVTL L., Issue # 2 (forthcoming) Abstract The Trump Administration’s implementation of its America First Energy Plan, whose goal is achieving U.S. “energy dominance,” has relied heavily upon public mineral development. Mineral development on federal lands is largely governed by statute. The statutory legal mechanisms by which the Executive Branch can “open” or “close” an area of federal lands to mineral development, whether onshore or offshore, are withdrawal, modification, and revocation. The Federal Land Policy and Management Act (FLPMA) and the Outer Continental Shelf Lands Act (OCSLA) are the primary statutes that govern onshore and offshore mineral development on over 2 billion acres of federal lands. Both FLPMA and OCSLA authorize withdrawals, which the Executive can use to place federal lands off limits to mineral development. FLPMA also authorizes modifications and revocations, which can remove constraints on such development. The Trump Administration has relied on both statutes in its quest to expand the areas that are available for private mineral disposition through modification or revocation of withdrawals by prior administrations. The authority provided by FLPMA and OCSLA to determine the availability of federal lands for mineral development is subject to a series of substantive and procedural constraints. -
APPENDIX 1A APPENDIX a UNITED STATES COURT of APPEALS, TENTH CIRCUIT ———— Nos
APPENDIX 1a APPENDIX A UNITED STATES COURT OF APPEALS, TENTH CIRCUIT ———— Nos. 17-7042, 17-7044 ———— The CHEROKEE NATION, Plaintiff-Appellee, v. DAVID BERNHARDT, in his official capacity as Secretary of the Interior, U.S. Department of the Interior; TARA KATUK MAC LEAN SWEENEY, in her official capacity as Acting Assistant Secretary for Indian Affairs, U.S. Department of the Interior; EDDIE STREATER, in his official capacity as Eastern Oklahoma Regional Director, Bureau of Indian Affairs, Defendants, and UNITED KEETOOWAH BAND OF CHEROKEE INDIANS IN OKLAHOMA; UNITED KEETOOWAH BAND OF CHEROKEEE INDIANS IN OKLAHOMA CORPORATION, Intervenors Defendants-Appellants. ———— 2a THE CHEROKEE NATION, Plaintiff-Appellee, v. DAVID BERNHARDT, in his official capacity as Secretary of the Interior, U.S. Department of the Interior; TARA KATUK MAC LEAN SWEENEY, in her official capacity as Acting Assistant Secretary for Indian Affairs, U.S. Department of the Interior; EDDIE STREATER, in his official capacity as Eastern Oklahoma Regional Director, Bureau of Indian Affairs, Defendants-Appellants, and UNITED KEETOOWAH BAND OF CHEROKEE INDIANS IN OKLAHOMA; UNITED KEETOOWAH BAND OF CHEROKEEE INDIANS IN OKLAHOMA CORPORATION, Intervenors-Defendants. ———— Filed September 5, 2019 ———— OPINION EID, Circuit Judge. Intervenor-Appellant the United Keetoowah Band of Cherokee Indians in Oklahoma (UKB) is a federally recognized Indian tribe located in eastern Oklahoma. The UKB are descended from the historical Cherokee Indian tribe. In 2000, the UKB purchased an undevel- oped 76-acre parcel of land near Tahlequah, Oklahoma, with the intention of developing it into a tribal and cultural center (Subject Tract, or Subject Parcel). The 3a Subject Parcel sits entirely within the boundaries of the former reservation of Appellees the Cherokee Nation of Oklahoma (Nation). -
List of Government Officials (May 2020)
Updated 12/07/2020 GOVERNMENT OFFICIALS PRESIDENT President Donald John Trump VICE PRESIDENT Vice President Michael Richard Pence HEADS OF EXECUTIVE DEPARTMENTS Secretary of Health and Human Services Alex Azar II Attorney General William Barr Secretary of Interior David Bernhardt Secretary of Energy Danny Ray Brouillette Secretary of Housing and Urban Development Benjamin Carson Sr. Secretary of Transportation Elaine Chao Secretary of Education Elisabeth DeVos (Acting) Secretary of Defense Christopher D. Miller Secretary of Treasury Steven Mnuchin Secretary of Agriculture George “Sonny” Perdue III Secretary of State Michael Pompeo Secretary of Commerce Wilbur Ross Jr. Secretary of Labor Eugene Scalia Secretary of Veterans Affairs Robert Wilkie Jr. (Acting) Secretary of Homeland Security Chad Wolf MEMBERS OF CONGRESS Ralph Abraham Jr. Alma Adams Robert Aderholt Peter Aguilar Andrew Lamar Alexander Jr. Richard “Rick” Allen Colin Allred Justin Amash Mark Amodei Kelly Armstrong Jodey Arrington Cynthia “Cindy” Axne Brian Babin Donald Bacon James “Jim” Baird William Troy Balderson Tammy Baldwin James “Jim” Edward Banks Garland Hale “Andy” Barr Nanette Barragán John Barrasso III Karen Bass Joyce Beatty Michael Bennet Amerish Babulal “Ami” Bera John Warren “Jack” Bergman Donald Sternoff Beyer Jr. Andrew Steven “Andy” Biggs Gus M. Bilirakis James Daniel Bishop Robert Bishop Sanford Bishop Jr. Marsha Blackburn Earl Blumenauer Richard Blumenthal Roy Blunt Lisa Blunt Rochester Suzanne Bonamici Cory Booker John Boozman Michael Bost Brendan Boyle Kevin Brady Michael K. Braun Anthony Brindisi Morris Jackson “Mo” Brooks Jr. Susan Brooks Anthony G. Brown Sherrod Brown Julia Brownley Vernon G. Buchanan Kenneth Buck Larry Bucshon Theodore “Ted” Budd Timothy Burchett Michael C. -
Republican Party Precinct Report — Official
Republican Party Precinct Report — Official Montgomery County, Texas — Primary Election — March 02, 2010 Page 1 of 510 03/09/2010 09:06 AM Total Number of Voters : 41,101 of 242,862 = 16.92% Precincts Reporting 85 of 85 = 100.00% Party Candidate Early Election Total Precinct 01 (Ballots Cast: 121) United States Representative, District 8, Vote For 1 Republican Party Scott Baker 6 14.29% 12 16.44% 18 15.65% Tyler Russell 3 7.14% 2 2.74% 5 4.35% Melecio Franco 0 0.00% 1 1.37% 1 0.87% Kevin Brady 33 78.57% 58 79.45% 91 79.13% Cast Votes: 42 93.33% 73 96.05% 115 95.04% Over Votes: 0 0.00% 0 0.00% 0 0.00% Under Votes: 3 6.67% 3 3.95% 6 4.96% Governor, Vote For 1 Republican Party Debra Medina 4 9.09% 13 17.33% 17 14.29% Kay Bailey Hutchison 10 22.73% 15 20.00% 25 21.01% Rick Perry 30 68.18% 47 62.67% 77 64.71% Cast Votes: 44 97.78% 75 98.68% 119 98.35% Over Votes: 0 0.00% 0 0.00% 0 0.00% Under Votes: 1 2.22% 1 1.32% 2 1.65% Lieutenant Governor, Vote For 1 Republican Party David Dewhurst 34 100.00% 65 100.00% 99 100.00% Cast Votes: 34 75.56% 65 85.53% 99 81.82% Over Votes: 0 0.00% 0 0.00% 0 0.00% Under Votes: 11 24.44% 11 14.47% 22 18.18% Attorney General, Vote For 1 Republican Party Greg Abbott 36 100.00% 64 100.00% 100 100.00% Cast Votes: 36 80.00% 64 84.21% 100 82.64% Over Votes: 0 0.00% 0 0.00% 0 0.00% Under Votes: 9 20.00% 12 15.79% 21 17.36% Comptroller Of Public Accounts, Vote For 1 Republican Party Susan Combs 35 100.00% 65 100.00% 100 100.00% Cast Votes: 35 77.78% 65 85.53% 100 82.64% Over Votes: 0 0.00% 0 0.00% 0 0.00% Under Votes: