Antibacterial Agent Susceptiblity and Resistance & Bacterial Anatomcial

ANTIBACTERIAL AGENT SUSCEPTIBLITY AND RESISTANCE & BACTERIAL ANATOMCIAL SITE ANALYSIS

LOUISIANA VETERINARY MEDICAL DIAGNOSTIC LABORATORY 2004

PRELIMINARY REPORT Section II (April 3, 2006)

Prepared by:

Gary A. Balsamo, DVM, MPH & TM, Infectious Disease Epidemiology Section Office of Public Health Louisiana Department of Health and Hospitals 1450 L & A Road Metairie, LA 70001 II. Susceptibility profiles for specific bacteria or bacterial groups

Bacterial species or genera susceptibility/resistance profiles are displayed in this section. If over ten isolates from individual bacterial species were available, antibiotic activity against the individual bacterial species was examined. In many cases if isolates of one bacterial species were numerous but isolates of related genera were less than ten, the smaller number of isolates from related bacterial species was included in the genera group. Genera that featured less than 10 samples submitted to the LVMDL over the 2004 calendar year were excluded. Some of the isolates were not identified to bacterial species, but instead were categorized as non-fermenters, gram-positive rods, or gram-negative rods. These categories were analyzed in the same manner as the specified genera.

There are four sections that comprise the genera profile: A. A graph illustrating the susceptibility/resistance profiles of selected antimicrobial agents tested on isolates of the organism B. A table showing percent susceptibility for selected antimicrobial agents on isolates of the organism. Agents effective against 90% or greater of the bacterial samples are illustrated in white boxes; those effective against 80% or greater are illustrated in light grey boxes; and those effective against 70% or greater are illustrated in darker grey boxes. Agents effective against less than 70% of the samples are illustrated in black boxes. C. The number (n) and percentage of bacterial isolates of the organism from each animal species is shown with a graph illustrating the animal species origin of the samples studied. D. A graph portraying the anatomical site of sample origin and the animal species of origin. In this graph the following abbreviations or short terms refer to the anatomical sites of origin listed to the right:

ABSCESS abscess PERFLUID peritoneal fluid (peritoneal (abscess, draining tract) flush, abdominal fluid) AV_GI/REP avian lower gastrointestinal REPD female reproductive tract and reproductive tracts (vagina, uterus) (cloaca, choana, vent) REPD(MALE) male reproductive tract BLOOD blood (penis, prostate flush, prepuce) BONE bone RESP respiratory CSF cerebrospinal fluid (lungs, alveolus, bronchial wash) EAR ear SKIN skin EYE eye (skin biopsy) (conjunctiva) SXSITE surgical site FOOT foot THRFLUID thoracic fluid GI gastrointestinal tract (pleural fluid, chest fluid) IMPLANT implant UMBILICUS umbilicus (implant site) (navel, umbilical cord) JOINT joint URINARY urinary (urine, bladder stone, (joint flush, joint fluid, bursal fluid) urine sample) LYMPHNODE lymph node URT upper respiratory tract (lymphatic fluid) (trans-tracheal wash, tracheal MILK milk wash, nasal flush) (mammary gland, teat, milk) WOUND wound MOUTH mouth abscess

1 A. Actinobacillus species (Actinobacillus spp, Actinobacillus equili) Resistant Actinobacillus Species Susceptible

Amikacin Gentamicin Cephalothin Ceftazidime Ceftiofur Chloramphenicol Tetracycline Erythromycin Antibiotics Nitrofurans Penicillin Ampicillin Ticarcillin Enrofloxacin Tribrissen Triple Sulfa

0 5 10 n 15 20 25

1. Table 2. Animal Species: Actinobacillus Percent Susceptible to Antibiotics Actinobacillus Antibiotics Percent Amikacin 86.4 Gentamicin 100 Cephalothin 94.7 Equine 23 Ceftazidime 95.7 (100% ) Ceftiofur 95.5 Chloramphenicol 100 Tetracycline 85 Erythromycin 100 0102030

Nitrofurans 95.2 Penicillin 72.7 3. Anatomical Sites Ampicillin 65 Equine Actinobacillus Sites by Species Ticarcillin 100 Enrofloxacin 100 16 Tribrissen 69.6 14 Triple Sulfa 60.9 12

8 14 6

4 5 2 4

0 RESP REPD OTHER

2 B. Corynebacterium spp (Corynebacterium spp, Corynebacterium pseudotuberculosis) Resistant Susceptible Corynebacterium Species Amikacin Gentamicin Kanamycin Cephalothin Ceftazidime Chloramphenicol Tetracycline Erythromycin

Antibiotics Clindamycin Penicillin Ampicillin Ticarcillin Augmentin Ciprofloxacin Enrofloxacin Marbofloxacin Tribrissen Triple Sulfa

0 5 10 n 15 20 25

1. Table 2. Animal Species: Cornyebacterium Percent Corynebacterium Susceptible to Antibiotics

Antibiotics Percent Bovine 2 (8.3%) Amikacin 100 Gentamicin 91.3 Canine 12 (50.0%) Kanamycin 81.3 Caprine 3 (12.5%) Cephalothin 76.2 Ceftazidime 56.5 Equine 5 (20.8%) Chloramphenicol 91.3 2 (8.3%) Tetracycline 95.7 Feline Erythromycin 100 0 5 10 15 Clindamycin 93.8

Penicillin 70.8 3. Anatomical Sites Ampicillin 77.3 Ticarcillin 72.2 Corynebacterium Sites by Species Augmentin 68.8 12

Ciprofloxacin 45.5 10 Enrofloxacin 57.1 2 Equine 8 Marbofloxacin 50 1 Bovine Tribrissen 45.8 6 Feline 4 Caprine 4 Triple Sulfa 54.2 7 Canine 1 2 3 2 2 2 0

S N EAR ES W MILK C O N OTHER BS A NK U

3 C. E Coli Resistant Susceptible E. coli Amikacin Gentamicin Kanamycin Neomycin Tobramycin Cephalothin Cefotaxime Ceftazidime Ceftiofur Chloramphenicol Doxycycline Tetracycline Clindamycin Erythromycin

Antibiotics Nitrofurans Penicillin Ampicillin Ticarcillin Augmentin Oxacillin Ciprofloxacin Enrofloxacin Marbofloxacin Tribrissen Triple Sulfa

0 50 100 n 150 200 250

1. Table 2. Animal Species: E. coli Percent AVIAN 10 4.5% CAPRINE 2 0.9% PRIMATE 2 0.9% Susceptible to Antibiotics Antibiotics Percent BOVINE 2 0.9% EQUINE 18 8.1% REPTILE 2 0.9% Amikacin 96 CANINE 137 62.0% FELINE 41 18.6% UNKNOWN 4 1.8% Gentamicin 84 Kanamycin 83 3. Anatomical Sites Neomycin 100 Tobramycin 73 Cephalothin 42

Ceftaxime 100

Ceftazidime 87 TOTALS AVIAN BOVINE CANINE CAPRINE EQUINE FELINE PRIMATE REPTILE RODENT UNKNOWN Ceftiofur 87 Chloramphenicol 88 ABSCESS 2 3 2 1 1 9 Doxycycline 74 AV_GI/REP 1 3 4 Tetracycline 74 EAR 8 2 10 Clindamycin 1 IMPLANT 8 1 1 10 Erythromycin 1 PERFLUID 2 2 1 5 Nitrofurans 90 REPD 3 6 9 Penicillin 1 RESP 2 1 1 4 Ampicillin 41 SKIN 2 2 Ticarcillin 58 SXSITE 2 1 3 Augmentin 75 Oxacillin 1 URINARY 86 1 1 26 1 115 Ciprofloxacin 72 URT 2 1 3 1 7 Enrofloxacin 77 WOUND 3 1 4 Marbofloxacin 75 OTHER 1 1 4 2 1 9 Tribrissen 75 UNKNOWN 4 13 1 3 5 2 1 1 1 31 Triple Sulfa 60 TOTALS 8 3 140 2 18 41 2 2 3 3 222

4 D. Enterobacter Species (Enterobacter spp, Enterobacter cloacae, Enterobacter aerogenes) Resistant Enterobacter Species Susceptible

Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Oxacillin

s Augmentin Ticarcillin Ampicillin

Antibiotic Penicillin Erythromycin Clindamycin Tetracycline Chloramphenicol Ceftiofur Ceftazidime Cephalothin Kanamycin Gentamicin Amikacin n 0 5 10 15 20 25 30 35 40

1. Table 2. Animal Species:

Enterobacter Percent Enterobacter spp Susceptible to Antibiotics Antibiotics Percent AVIAN 2 (5.9%) Amikacin 90 19 (55.9%) CANINE Gentamicin 88.2 Kanamycin 95.7 EQUINE 9 (26.5%) Cephalothin 7.4 FELINE 1 (2.9) Ceftazidime 90.9 Ceftiofur 80 PRIMATE 1 (2.9%) Chloramphenicol 78.1 UNKNOWN 2 (5.9%) Tetracycline 87 0 5 10 15 20 Erythromycin 0 Clindamycin 4.2 Penicillin 3.3 2. Anatomical Sites: Ampicillin 18.5 Ticarcillin 71.4 Augmentin 45.5

Oxacillin 0 TOTALS

Enrofloxacin 92 AVIAN CANINE EQUINE FELINE PRIMATE UNKNOWN Marbofloxacin 100 BLOOD 4 4 Tribrissen 81.3 IMPLANT 2 1 1 4 Triple Sulfa 72.7 RESPD 2 2 (MALE) URINARY 7 1 8 OTHER 3 3 6 UNKNOWN 2 5 1 1 1 10 TOTALS 2 19 9 1 1 2 34 5 E. Enterococcus spp Resistant Susceptible Enterococcus species

Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ampicillin Penicillin

Antibiotics Clindamycin Tetracycline Chloramphenicol Ceftazidime Cephalothin Kanamycin Gentamicin n 0 5 10 15 20 25 30 35 40 45 50

1. Table 2. Animal Species: Enterococcus Percent Enterococcus Spp Susceptible to Antibiotics 1 (2.2%) Antibiotics Percent AVIAN Gentamicin 73.3 Kanamycin 52.6 CANINE 31 (68.9%) Cephalothin 20 EQUINE 1 (2.2%) Ceftazidime 10.6 11 (24.4%) Chloramphenicol 64.3 FELINE Tetracycline 41 Clindamycin 14 RODENT 1 (2.2%) Penicillin 75.6 0 5 10 15 20 25 30 35 Ampicillin 76.7 Augmentin 90.5 3. Anatomical Sites: Oxacillin 5 Ciprofloxacin 45.5 Enrofloxacin 21.9 Marbofloxacin 59.4 TOTALS Tribrissen 29.8 AVIAN CANINE EQUINE FELINE RODENT Triple Sulfa 4.3 ABSCESS 2 2 EAR 4 4 IMPLANT 2 2 URINARY 18 7 25 WOUND 2 2 OTHER 1 3 1 2 1 8 UNKNOWN 2 2 TOTALS 1 31 1 11 1 45

6 F. Gram Negative Rods Resistant Susceptible Gram Negative Rods

Triple Sulfa

Tribrissen

Enrofloxacin Antibiotics Ceftazidime

Gentamicin

0246810n 12

1. Table 2. Animal Species: Gram Negative Rods Gram Negative Rods Percent Susceptible to Antibiotics Antibiotics Percent AVIAN 2 (18.2%) Gentamicin 90.9 4 (36.4)% Ceftazidime 90 CA NINE Enrofloxacin 100 Tribrissen 80 EQUINE 2 (18.2%) Triple Sulfa 80

FELINE 1 (9.1%)

REPTILE 2 (18.2%)

012345

3. Anatomical Site:

Gram Negative Rods Sites by Species 5

4 1 3 1 2 3 1 2 2 2

0 URT GI OTHER UNKNOWN

7 G Gram Positive Rods Resistant Susceptible Gram Positive Rods

Triple Sulfa

Tribrissen

Enrofloxacin

Ampicillin Antibiotics Penicillin

Chloramphenicol

Ceftazidime

Gentamicin

024681012n 14

1. Table 2. Animal Species: Gram Positive Rods Percent Gram Positive Rods Susceptible to Antibiotics Antibiotics Percent AVIAN 2 (16.7%) Gentamicin 91.7 1 (8.3%) Ceftazidime 66.7 BOVINE Chloramphenicol 81.8 CANINE 6 (50%) Penicillin 90 Ampicillin 90 EQUINE 2 (16.7%) Enrofloxacin 72.7 Tribrissen 45.5 FELINE 1 (8.3%) Triple Sulfa 58.3 012345678

3. Anatomical Sites:

Gram Positive Rods Sites by Species 5

4 11

3 1 2 2 3 1 1 11 1

0 ABSCESS EAR OTHER UNKNOWN

8 H. Klebsiella spp (Klebsiella pneumoniae, Klebsiella spp) Resistant Susceptible Klebsiella Species Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin

Antibiotics Penicillin Erythromycin Clindamycin Tetracycline Doxycycline Chloramphenicol Ceftiofur Ceftazidime Cephalothin Kanamycin Gentamicin Amikacin

0 1020304n 0506070

1. Table 2. Animal Species:

Klebsiella Percent Klebsiella Susceptible to Antibiotics UNKNOWN 1 (1.7%) Antibiotics Percent AVIAN 4 (6.8%) Amikacin 86.7 39 (66.1%) Gentamicin 84.2 CANINE Kanamycin 82.6 EQUINE 7 (11.9%) Cephalothin 56.3 FELINE 4 (6.8%) Ceftazidime 83.6 REPTILE 3 (5.1%) Ceftiofur 71.4 RODENT 1 (1.7%) Chloramphenicol 78.9 0 5 10 15 20 25 30 35 40 Doxycycline 85.7 Tetracycline 82.2 3. Anatomical Site: Erythromycin 0 Clindamycin 0 Penicillin 0

Ampicillin 3.8 TOTALS AVIAN AVIAN CANINE EQUINE FELINE REPTILE RODENT UNKNOWN Ticarcillin 22.7 ABSCESS 1 1 2 Augmentin 72 Oxacillin 0 AV_GI/REP 2 2 Ciprofloxacin 95.7 EAR 2 2 Enrofloxacin 89.3 IMPLANT 2 1 3 Marbofloxacin 91.7 REPD 1 1 1 3 Tribrissen 76.2 SXSITE 1 1 2 Triple Sulfa 69.8 URINARY 23 1 1 25 URT 2 2 1 5 WOUND 1 1 2 OTHER 3 1 1 5 UNKNOWN 4 2 2 8 TOTALS 4 39 7 4 3 1 1 59 9 I. Nonfermenters Resistant Susceptible Nonfermenters Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin Penicillin Nitrofurans

Antibiotics Erythromycin Clindamycin Tetracycline Doxycycline Chloramphenicol Ceftiofur Ceftazidime Cephalothin Kanamycin Gentamicin Amikacin

0 10203n 0405060

1. Table 2. Animal Species: Nonfermenters Percent AVIAN 5 10.0% CANINE 17 34.0% MARSUP 1 2.0% Susceptible to Antibiotics BOVINE 1 2.0% EQUINE 13 26.0% PORCINE 1 2.0% Antibiotics Percent CAMELID 2 4.0% FELINE 6 12.0% REPTILE 3 6.0% Amikacin 89.3 Gentamicin 86 RODENT 1 2.0% Kanamycin 92 Cephalothin 52.6 3. Anatomical Sites: Ceftazidime 82.7 Ceftiofur 68 Chloramphenicol 75 Doxycycline 66.7 TOTALS

Tetracycline 72.5 AVIAN BOVINE CAMELID CANINE EQUINE FELINE MARSUP PORCINE REPTILE RODENT Erythromycin 57.9 ABSCESS 1 1 2 Clindamycin 11.5 AV_GI/REP 2 2 Nitrofurans 50 EYE 1 1 2 Penicillin 42.9 IMPLANT 3 3 Ampicillin 42.5 Ticarcillin 78.6 REPD 2 2 Augmentin 73.5 RESP 1 3 1 5 Oxacillin 7.1 THRFLUID 2 2 Ciprofloxacin 83.3 URINARY 4 1 5 Enrofloxacin 80 URT 1 1 1 6 1 1 11 Marbofloxacin 88.9 OTHER 1 3 1 2 7 Tribrissen 75 UNKNOWN 1 1 3 1 3 9 Triple Sulfa 67.9 TOTALS 5 1 2 17 13 6 1 1 3 1 50

10 J. Pasteurella spp (Pasteurella multocida, Pasteurella spp) Resistant Susceptible Pasteurella Species

Triple Sulfa

Tribrissen

Marbofloxacin

Enrofloxacin

Augmentin s Ampicillin

Penicillin Antibiotic Clindamycin

Tetracycline

Chloramphenicol

Ceftazidime

Cephalothin

Kanamycin

Gentamicin n 0 5 10 15 20 25 30 35 40

1. Table 2. Animal Species Pasteurella Percent Pasteurella Susceptible to Antibiotics

Antibiotics Percent AVIAN 1 (2.9%) Gentamicin 100 Kanamycin 92.9 BOVINE 6 (17.6%) Cephalothin 75 Ceftazidime 97.1 CANINE 12 (35.3%) Chloramphenicol 94.1 Tetracycline 91.7 FELINE 14 (41.2%) Clindamycin 3.4 UNKNOWN 1 (2.9%) Penicillin 70.6 -1 1 3 5 7 9 11 13 15 Ampicillin 79.4 Augmentin 96.6 Enrofloxacin 96.7 3. Anatomical Site: Marbofloxacin 100 Tribrissen 76.5 Triple Sulfa 61.1

TOTALS AVIAN BOVINE CANINE FELINE UNKNOWN

ABSCESS 1 2 3 EAR 2 2 LYMPHNODE 1 1 RESP 2 1 3 THRFLUID 1 1 2 URT 1 3 3 7 WOUND 1 1 1 3 OTHER 1 1 1 3 UNKNOWN 1 2 4 3 10 TOTALS 1 6 12 14 1 34

11 K. Proteus spp (Proteus mirabilis, Proteus spp) Resistant Susceptible Proteus Species Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin Penicillin Erythromycin Antibiotics Clindamycin Polymyxin B Tetracycline Chloramphenicol Ceftazidime Cephalothin Tobramycin Neomycin Kanamycin Gentamicin Amikacin

0 1020304n 050607080

1. Table 2. Animal Species: Proteus Percent AVIAN 2 3.0% FELINE 5 7.5% RODENT 1 1.5% Susceptible to Antibiotics CANINE 57 85.1% MUSTELID 1 1.5% UNKNOWN 1 1.5% Antibiotics Percent

Amikacin 100 3. Anatomical Site: Gentamicin 95.5 Kanamycin 93.3 Neomycin 100

Tobramycin 100

Cephalothin 73.2 TOTALS AVIAN CANINE FELINE MUSTELID RODENT UNKNOWN Ceftazidime 98.5 Chloramphenicol 55.6 EAR 24 24 Tetracycline 7.3 URINARY 18 2 20 Polymyxin B 0 URT 2 2 Erythromycin 0 WOUND 1 1 2 Clindamycin 1.6 OTHER 1 4 2 1 1 8 Penicillin 8.2 UNKNOWN 1 8 1 10 Ampicillin 79.3 TOTALS 2 57 5 1 1 1 66 Ticarcillin 96 Augmentin 83.6 Oxacillin 2.4 Ciprofloxacin 97.2 Enrofloxacin 89.1 Marbofloxacin 94.4 Tribrissen 79.1 Triple Sulfa 67.7

12 L. Pseudomonas aeruginosa Resistant Pseudomonas aeruginosa Susceptible Amikacin Gentamicin Kanamycin Neomycin Tobramycin Cephalothin Ceftazidime Ceftiofur Chloramphenicol Doxycycline Tetracycline s Polymyxin B Clindamycin Erythromycin

Antibiotic Nitrofurans Penicillin Ampicillin Ticarcillin Piperacillin Augmentin Oxacillin Ciprofloxacin Enrofloxacin Marbofloxacin Tribrissen Triple Sulfa

0 20 40 60n 80 100 120 140

1. Table 2. Animal Species: Pseudomonas aeruginosa AVIAN 7 6.0% CERVINE 2 1.7% FELINE 8 6.8% Percent Susceptible to Antibiotics CANINE 85 72.6% EQUINE 8 6.8% REPTILE 6 5.1% Antibiotics Percent Amikacin 98.6 UNKNOWN 1 0.9% Gentamicin 85 Kanamycin 1.1 3. Anatomical Site: Neomycin 44.4 Tobramycin 91.8 Cephalothin 0 Ceftazidime 97.4

Ceftiofur 26.7 TOTALS

Chloramphenicol 0 AVIAN CANINE CERVINE EQUINE FELINE REPTILE UNKNOWN Doxycycline 4.3 ABSCESS 2 1 3 Tetracycline 0 Polymyxin B 90.6 EAR 42 3 45 Erythromycin 0 FOOT 2 1 1 4 Clindamycin 1 IMPLANT 6 1 7 Nitrofurans 0 MOUTH 1 1 2 Penicillin 0 Ampicillin 0 SKIN 1 1 2 Ticarcillin 91.8 SXSITE 1 2 1 4 Piperacillin 97.5 URINARY 7 1 8 Augmentin 0.9 URT 3 2 2 7 Oxacillin 0 Ciprofloxacin 80.8 WOUND 4 2 6 Enrofloxacin 24.3 OTHER 1 1 1 3 Marbofloxacin 74 UNKNOWN 2 19 1 2 2 26 Tribrissen 1.5 TOTALS 7 85 2 8 8 6 1 117 Triple Sulfa 19.4 13 M. Pseudomonas species (Pseudomonas malei, Pseudomonas maltophilia, Pseudomonas spp) Resistant Pseudomonas Species Susceptible Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin Penicillin Clindamycin Polymyxin B Tetracycline

Antibiotics Chlorampheni Ceftazidime Cephalothin Tobramycin Neomycin Kanamycin Gentamicin Amikacin

0 10203n 04050

1. Table 2. Animal Species: Pseudomonas species Pseudomonas Species Percent Susceptible to Antibiotics 1 (2.6%) BOVINE Antibiotics Percent Amikacin 80 CANINE Gentamicin 76.3 27 (69.2%) 2 (5.1%) Kanamycin 48.5 EQUINE Neomycin 84.6 7 (17.9%) Tobramycin 78.6 FELINE

Cephalothin 16 2 (5.1%) Ceftazidime 87.2 REPTILE Chloramphenicol 50 0 5 10 15 20 25 30

Tetracycline 55.6 Polymyxin B 72.7 3. Anatomical Site: Clindamycin 2.9 Pseudomonas Sites by Species Penicillin 3.2 12 Ampicillin 14.8 Ticarcillin 60.9 10 Augmentin 39.4 8 Oxacillin 0 11 6 Ciprofloxacin 70.8 1 Enrofloxacin 73 4 Marbofloxacin 79.3 5 12 1 Tribrissen 60.6 2 3 1 13 Triple Sulfa 66.7 2 0 1 2 R P R Y IN D E 1 A R WN K N E A O URT S U RES IN N O OTH R K W U N U 14 N. Salmonella Resistant Susceptible Salmonella Triple Sulfa Tribrissen Enrofloxacin Ticarcillin Ampicillin Penicillin Nitrofurans Erythromyci Tetracycline

Antibiotics Chloramphe Ceftiofur Ceftazidime Cephalothin Gentamicin Amikacin

0102n 03040

1. Table 2. Animal Species: Salmonella Percent Salmonella Susceptible to Antibiotics

Antibiotics Percent AVIAN 3 (8.3%) Amikacin 97.1 CANINE 1 (2.8%) Gentamicin 93.9 31 (86.1%) Cephalothin 96.4 EQUINE

Ceftazidime 91.4 UNKNOWN 1 (2.8%) Ceftiofur 93.8 0 5 10 15 20 25 30 35 Chloramphenicol 93.3 Tetracycline 92.9 Erythromycin 6.3 3. Anatomical Site:

Nitrofurans 100 Salmonella Sites by Species Penicillin 3.3 30 Ampicillin 93.3 Ticarcillin 93.9 25 Enrofloxacin 73 Tribrissen 60.6 Triple Sulfa 66.7 20

15 27

5 1 1 2 3 0 11 AV_GI/REP OTHER GI JOINT

15 O. Staphylococcus intermedius Resistant Staphylococcus intermedius Susceptible

Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin Penicillin Erythromycin Clindamycin Polymyxin B

Antibiotics Tetracycline Doxycycline Chloramphenicol Ceftazidime Cephalothin Tobramycin Neomycin Kanamycin Gentamicin

0 204060801001n 20

1. Table 2. Animal Species:

Staphylococcus intermedius Staphylococcus intermedius Percent Susceptible to Antibiotics Antibiotics Percent CANINE 103 (91.2%) Gentamicin 94.6 9 (8%) Kanamycin 88.2 FELINE Neomycin 97.4 1 (0.9%) Tobramycin 97.1 UNKNOWN Cephalothin 99 Ceftazidime 93.8 0 20406080100

Chloramphenicol 99.1 Tetracycline 84.8 3. Anatomical Site: Polymyxin B 75.9 Doxycycline 90 Staphylococcus intermedius Sites by Species 45 Clindamycin 90.2 1 Erythromycin 92.3 40 Penicillin 44.4 35 Ampicillin 46.2 30 Ticarcillin 97.3 25 3 20 42 Augmentin 100 4 15 Oxacillin 92.5 24 10 Ciprofloxacin 88.5 16 5 1 Enrofloxacin 91.3 6 5 1 2 3 1 4 Marbofloxacin 92.9 0 R AR E KIN Tribrissen 86.3 E S TH XSITE OUND O S BSCESS RINARY MPLANT W Triple Sulfa 72.6 A NKNOWN U I U

16 P. Staphylococcus species (Staphylococcus coagulase positive, Staphylococcus coagulase negative, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus spp) Resistant Susceptible Staphylococcus Species Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin Penicillin

Antibiotics Nitrofurans Erythromycin Clindamycin Polymyxin B Tetracycline Chloramphenicol Ceftiofur Ceftazidime Cephalothin Tobramycin Neomycin Kanamycin Gentamicin Amikacin

0 20 40 n 60 80 100 120

1. Table 2. Animal Species: Staphylococcus species AVIAN 6 5.4% CAPRINE 1 0.9% LAGOMORPH 1 0.9% PORCINE 1 0.9% Percent Susceptible to Antibiotics BOVINE 3 2.7% EQUINE 17 15.3% MARSUP 1 0.9% REPTILE 1 0.9% Antibiotics Percent CANINE 54 48.6% FELINE 20 18.0% MUSTELID 1 0.9% RODENT 1 0.9% Amikacin 93.8 Gentamicin 90.1 UNKNOWN 4 3.6% Kanamycin 79.5 3. Anatomical Site: Neomycin 93.8 Tobramycin 93.8 Cephalothin 93.3

Ceftazidime 78.1 Ceftiofur 90 AVIAN BOVINE CANINE CAPRINE EQUINE FELINE LAGOMORPH MARSUP MUSTELID PORCINE REPTILE RODENT UNKNOWN TOTALS Chloramphenicol 94.4 Tetracycline 80.5 ABSCESS 2 2 1 5 Polymyxin B 64.3 AV_GI/REP 2 2 2 2 Clindamycin 83.5 BONE CSF 1 1 2 Erythromycin 81.8 EAR 11 3 14 Nitrofurans 95.5 EYE 1 2 3 Penicillin 42.9 FOOT 3 1 4 Ampicillin 42.4 IMPLANT 3 1 4 Ticarcillin 91.1 JOINT 1 2 4 7 Augmentin 94.3 MILK 2 1 2 5 Oxacillin 68.6 REPD 2 2 Ciprofloxacin 94.6 SKIN 3 1 4 Enrofloxacin 89.5 URINARY 9 7 1 1 18 Marbofloxacin 89.4 URT 1 2 3 Tribrissen 83.3 WOUND 2 1 1 4 Triple Sulfa 71.6 OTHER 3 3 1 7 UNKNOWN 2 13 1 7 1 1 25 TOTALS 6 3 54 1 17 20 1 1 1 1 1 1 4 111 17 Q. Streptococcus Species Alpha Hemolytic Resistant Susceptible Streptococcus Species Alpha Hemolytic Triple Sulfa Tribrissen Enrofloxacin Ciprofloxacin Augmentin Ticarcillin Ampicillin Penicillin Erythromyci

Antibiotics Tetracycline Chloramphe Ceftiofur Ceftazidime Cephalothin Gentamicin Amikacin

0 5 10 n 15 20 25

1. Table 2. Animal Species: Streptococcus Species Alpha Hemolytic Streptococcus Alpha Hemolytic Percent Susceptible to Antibiotics AVIAN 3 (13.6%) Antibiotics Percent BOVINE 1 (4.5%) Amikacin 35.7 CANINE 5 (22.7%) Gentamicin 66.7 1 (4.5%) Cephalothin 80 CAPRINE Ceftazidime 60 EQUINE 9 (40.9%) Ceftiofur 75 FELINE 2 (9.1%) Chloramphenicol 88.2 LAGOMOR 1 (4.5%) Tetracycline 58.8 0123456789 Erythromycin 83.3 Penicillin 60 Ampicillin 77.8 3. Anatomical Site: Ticarcillin 81.3 Streptococcus Alpha Hemolytic Sites by Species Augmentin 90 5 Ciprofloxacin 60 Enrofloxacin 47.1 Tribrissen 31.8 4 Triple Sulfa 15 1 1 3

2 2 4

133

1 2 2

1 1

0 UNKNOWN URINARY AV_GI/REP EAR OTHER URT REPD

18 R. Streptococcus Species Beta Hemolytic Resistant Susceptible Streptococcus Species Beta Hemolytic Triple Sulfa Tribrissen Marbofloxacin Enrofloxacin Ciprofloxacin Oxacillin Augmentin Ticarcillin Ampicillin Penicillin Erythromycin Clindamycin Antibiotics Tetracycline Chloramphenicol Ceftiofur Ceftazidime Cephalothin Kanamycin Gentamicin Amikacin

0 5 10 15 20n 25 30 35 40 45 50

1. Table 2. Animal Species:

Streptococcus Species Beta Hemolytic Streptococcus Beta Hemolytic Percent Susceptible to Antibiotics CANINE 35 (72.9%) Antibiotics Percent 8 (16.7%) Amikacin 0 EQUINE 2 (4.2%) Gentamicin 93.8 FELINE Kanamycin 17.9 1 (2.1%) Cephalothin 100 PORCINE 2 (4.2%) Ceftazidime 100 UNKNOWN Ceftiofur 100 0 5 10 15 20 25 30 35 Chloramphenicol 97.8

Tetracycline 33.3 3. Anatomical Site: Clindamycin 100 Erythromycin 100 Beta Hemolytic Streptococcus Sites by Species Penicillin 100 10 Ampicillin 100 9

Ticarcillin 95 8 Augmentin 100 7 Oxacillin 81.8 1 1 6 Ciprofloxacin 78.9 1 1 5 Enrofloxacin 82.6 1 9 Marbofloxacin 92 4 1 Tribrissen 75 3 66 5 Triple Sulfa 8.5 2 4 2 3 3 3 1 1 0 ABSCESS OTHER EAR JOINT UNKNOWN URT URINARY REPD WOUND

19 S. Streptococcus Species Gamma Hemolytic Resistant Susceptible Streptococcus Species Gamma Hemolytic Triple Sulfa Tribrissen Enrofloxacin Ciprofloxacin Augmentin Ampicillin Penicillin Erythromycin Antibiotics Clindamycin Tetracycline Chloramphenicol Ceftazidime Cephalothin Kanamycin Gentamicin

02468101214161820n

1. Table 2. Animal Species:

Streptococcus Species Gamma Hemolytic Streptococcus Gamma Hemolytic Percent Susceptible to Antibiotics AVIAN 5 (27.8%)

Antibiotics Percent CANINE Gentamicin 70.6 9 (50%) EQUINE 1 (5.6%) Kanamycin 58.3 Cephalothin 41.7 FELINE 2 (11.2%) Ceftazidime 22.2 RODENT 1 (5.6%)

Chloramphenicol 70.6 0123456789 Tetracycline 41.7 Clindamycin 16.7 Erythromycin 60 3. Anatomical Site: Penicillin 61.5 Gamma Hemolytic Streptococcus Sites by Species Ampicillin 83.3 7 Augmentin 87.5 Ciprofloxacin 81.8 6

Enrofloxacin 58.3 5 2 Tribrissen 44.4 Triple Sulfa 6.3 4 1 1 3

2 4 13 3 1 2 1 0 UNKNOWN OTHER AV_GI/REP EAR UNRINARY

20 T. Streptococcus zooepidemicus Resistant Susceptible Streptococcus zooepidemicus Triple Sulfa Tribrissen Enrofloxacin Ticarcillin Ampicillin Penicillin Nitrofurans Erythromyci Tetracycline

Antibiotics Chloramphe Ceftiofur Ceftazidime Cephalothin Gentamicin Amikacin

0 102n 03040

1. Table 2. Animal Species: Streptococcus Streptococcus zooepidemicus zooepidemicus Percent Susceptible to Antibiotics Antibiotics Percent 37 (100%) Amikacin 0 EQUINE Gentamicin 87.9 Cephalothin 100 0 10203040 Ceftazidime 94.6 Ceftiofur 100 Chloramphenicol 93.9 3. Anatomical Site: Tetracycline 17.6 Streptococcus zooepidemicus Sites by Species Erythromycin 100 14 Nitrofurans 100 Penicillin 100 12

Ampicillin 100 10 Ticarcillin 97.3 Enrofloxacin 50 8 13 Tribrissen 22.2 6 12 Triple Sulfa 5.4 4 2 3 33 2 1 0

T D R UID U L EP THER R RF O BSCESS A TH MBILICUS NKNOWN U U

21 U. Streptococcus spp (Streptococcus spp, Streptococcus dysgalactiae, Streptococcus equi equi, Streptococcus equisimilis, Streptococcus species non-hemolytic, Streptococcus species group L) Resistant Susceptible Streptococcus spp Amikacin Ampicillin Ceftazidime Ceftiofur Cephalothin Chloramphenicol Enrofloxacin Gentamicin

Antibiotics Nitrofurans Penicillin Tetracylcine Ticarcillin Tribrissen

0 5 n 10 15 20

Table 2. Animal Species: Streptococcus spp Percent Streptococcus Species Susceptible to Antibiotics 2 (11.8%) Antibiotics Percent BOVINE Amikacin 0 Ampicillin 92.9 CANINE 3 (17.6%) Ceftazidime 82.4 Ceftiofur 90.9 EQUINE 10 (58.8%) Cephalothin 100 1 (5.9%) Chloramphenicol 81.3 LAGOMOR

Tetracycline 83.3 REPTILE 1 (5.9%) Gentamicin 93.3 Nitrofurans 76.9 0246810

Penicillin 92.9 Ticarcillin 100 3. Anatomical Site: Enrofloxacin 60 Tribrissen 70.6 Streptococcus Species Sites by Species 8 Triple Sulfa 35.3 7 1 6

4 44 1 3

2 2

1 2 2 1 0 UNKNOWN OTHER URT