FERMENTATION FACILITY Providing fermentation services to industry clients and State University

www.ccur.iastate.edu/fermentationfacility A unique research facility

The Fermentation Facility is designed to help researchers develop new fermentation technologies and products and provide bench- and pilot-scale fermentation equipment.

The Fermentation Facility has equipment for scaling BioCentury Research Farm up the production of industrially important chemicals, The Fermentation Facility works jointly with the chemical feedstocks, genetically modified organisms BioCentury Research Farm to turn a variety of and enzymes. biomass feedstocks into ethanol and industrial chemicals using fermentation. Fermentation and Researchers have access to state-of-the-art processing capabilities are available, including equipment and expertise in the areas of microbial fermentation vessels of 500- and 1,000-liter working fermentation and product recovery. By using the volume capacities. facility’s equipment and expertise, industry clients have found a cost-effective way to test new products Researchers can test new processing systems using and processes. benchtop‑ and small pilot-scale equipment before going to large pilot scale at the BioCentury Research The Fermentation Facility is managed by the Center Farm. for Crops Utilization Research with additional funding provided by the College of Agriculture and Life For more information about the BioCentury Research Sciences. Farm, visit www.biocenturyresearchfarm.iastate.edu. Specialized research services

The Fermentation Facility offers a wide range of services to industry clients and Iowa State University researchers to assist in the development of new fermentation technologies and provide fermentation equipment at a reasonable cost.

Various Services Parallel Bench-scale and Expert Assistance »» Controlled growth of Long-term Fermentations Our technical staff has experience microorganisms from bench- to Users have the opportunity to scaling up commercially relevant large pilot-scale capacities simultaneously run multiple bench- processes, chemicals and materials. »» Simultaneous, parallel and scale fermentations. Experimental Expert assistance is available long-term fermentations designs that would take months for biotechnology courses or »» Continuous and batch to complete with one fermentor workshops. Additionally, training of fermentations can be completed in weeks by graduate students and technicians using a multiple-unit array. in the operation of batch and »» Downstream processing including continuous fermentation fermentors centrifugation, ultrafiltration, Some continuous and batch spray drying and freeze drying and microbial culture maintenance fermentations require use of one and preservation is available. »» Real-time analytics or more fermentors for extended »» Customized programs to fit the periods. Every attempt will be made specific needs of clients to assist researchers with scheduling »» Training for industry personnel and execution of these projects. and university students AVAILABLE EQUIPMENT

The Fermentation Facility has equipment for producing cellular biomass, chemicals, chemical feedstocks and enzymes, and converting grain and lignocellulose into fuels and products.

Bench-scale Fermentors with Analytic Equipment Computer Controls Automated Enzyme-based Analyzer 5-liter and 7-liter Spectrophotometer

Sterilizable-in-Place Fermentors Additional Equipment 15-liter, 50-liter, 120-liter, 200-liter, 500-liter and Autoclaves 1,000-liter Bio-hood Downstream Processing Equipment Chemical Hood French Pressure Cell (40-ml) Distillation Skid System Hollow Fiber Unit (20-liter) Falling Film Evaporator Horizontal Decanter Incubating Shakers (acoustic and orbital) Semi-continuous Centrifuge Jacketed Mixing Vessels (25- to 250-liter) Peristaltic Pumps Freeze Dryers Process Tanks (80-gallon and 350-gallon) Bench-scale Freeze Dryer Rotary Evaporator (1.5-liter condenser capacity) Rotary Steam Tube Drying System Eight-shelf freeze dryer with stoppering capability Spray Dryer that can be used for either bulk drying or producing dry product in vacuum sealed vials Ultralow Freezer (15-liter condenser capacity)

A fee schedule and a complete list of equipment are available online at www.ccur.iastate.edu/fermentationfacility.

1041 Food Sciences Building Phone: (515) 294-0160 Email: [email protected] 536 Farm House Lane Fax: (515) 294-6261 Web: www.ccur.iastate.edu Iowa State University Twitter: IowaStateCCUR Ames, Iowa 50011-1054

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