A Genomic Region Containing RNF212 and CPLX1 Is Associated with Sexually
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Cytogenomic SNP Microarray - Fetal ARUP Test Code 2002366 Maternal Contamination Study Fetal Spec Fetal Cells
Patient Report |FINAL Client: Example Client ABC123 Patient: Patient, Example 123 Test Drive Salt Lake City, UT 84108 DOB 2/13/1987 UNITED STATES Gender: Female Patient Identifiers: 01234567890ABCD, 012345 Physician: Doctor, Example Visit Number (FIN): 01234567890ABCD Collection Date: 00/00/0000 00:00 Cytogenomic SNP Microarray - Fetal ARUP test code 2002366 Maternal Contamination Study Fetal Spec Fetal Cells Single fetal genotype present; no maternal cells present. Fetal and maternal samples were tested using STR markers to rule out maternal cell contamination. This result has been reviewed and approved by Maternal Specimen Yes Cytogenomic SNP Microarray - Fetal Abnormal * (Ref Interval: Normal) Test Performed: Cytogenomic SNP Microarray- Fetal (ARRAY FE) Specimen Type: Direct (uncultured) villi Indication for Testing: Patient with 46,XX,t(4;13)(p16.3;q12) (Quest: EN935475D) ----------------------------------------------------------------- ----- RESULT SUMMARY Abnormal Microarray Result (Male) Unbalanced Translocation Involving Chromosomes 4 and 13 Classification: Pathogenic 4p Terminal Deletion (Wolf-Hirschhorn syndrome) Copy number change: 4p16.3p16.2 loss Size: 5.1 Mb 13q Proximal Region Deletion Copy number change: 13q11q12.12 loss Size: 6.1 Mb ----------------------------------------------------------------- ----- RESULT DESCRIPTION This analysis showed a terminal deletion (1 copy present) involving chromosome 4 within 4p16.3p16.2 and a proximal interstitial deletion (1 copy present) involving chromosome 13 within 13q11q12.12. This -
CATAIR Appendix
CBP and Trade Automated Interface Requirements Appendix: PGA April 24, 2020 Pub # 0875-0419 Contents Table of Changes ............................................................................................................................................4 PG01 – Agency Program Codes .................................................................................................................... 18 PG01 – Government Agency Processing Codes ............................................................................................. 22 PG01 – Electronic Image Submitted Codes.................................................................................................... 26 PG01 – Globally Unique Product Identification Code Qualifiers .................................................................... 26 PG01 – Correction Indicators* ...................................................................................................................... 26 PG02 – Product Code Qualifiers.................................................................................................................... 28 PG04 – Units of Measure .............................................................................................................................. 30 PG05 – Scie nt if ic Spec ies Code .................................................................................................................... 31 PG05 – FWS Wildlife Description Codes ..................................................................................................... -
St.Kilda Soay Sheep & Mouse Projects
ST. KILDA SOAY SHEEP & MOUSE PROJECTS: ANNUAL REPORT 2009 J.G. Pilkington 1, S.D. Albon 2, A. Bento 4, D. Beraldi 1, T. Black 1, E. Brown 6, D. Childs 6, T.H. Clutton-Brock 3, T. Coulson 4, M.J. Crawley 4, T. Ezard 4, P. Feulner 6, A. Graham 10 , J. Gratten 6, A. Hayward 1, S. Johnston 6, P. Korsten 1, L. Kruuk 1, A.F. McRae 9, B. Morgan 7, M. Morrissey 1, S. Morrissey 1, F. Pelletier 4, J.M. Pemberton 1, 6 6 8 9 10 1 M.R. Robinson , J. Slate , I.R. Stevenson , P. M. Visscher , K. Watt , A. Wilson , K. Wilson 5. 1Institute of Evolutionary Biology, University of Edinburgh. 2Macaulay Institute, Aberdeen. 3Department of Zoology, University of Cambridge. 4Department of Biological Sciences, Imperial College. 5Department of Biological Sciences, Lancaster University. 6 Department of Animal and Plant Sciences, University of Sheffield. 7 Institute of Maths and Statistics, University of Kent at Canterbury. 8Sunadal Data Solutions, Edinburgh. 9Queensland Institute of Medical Research, Australia. 10 Institute of Immunity and Infection research, University of Edinburgh POPULATION OVERVIEW ..................................................................................................................................... 1 REPORTS ON COMPONENT STUDIES .................................................................................................................... 4 Vegetation ..................................................................................................................................................... 4 Weather during population -
Sheep & Goat Catalogue
CIRENCESTER MARKET Rare, Native & Traditional Breeds Show & Sale of Cattle, Sheep, Pigs, Goats & Poultry SHEEP & GOAT CATALOGUE SATURDAY 4TH AUGUST 2018 SHOW TIMES Cotswold Sheep Show – Friday 3rd August 2018 at 5.00 p.m. Oxford Sandy & Black Pigs Show - Friday 3rd August 2018 at 4.30 p.m. SALE TIMES Poultry Sale - 10.00 a.m. Cotswold Sheep - 11.00 a.m. General Sheep - Follows Cotswold Sheep Sale Cattle - Follows Sheep Sale at Approx 12.45 p.m. Pigs - Follows Cattle Sale at Approx 1.45 p.m. Flowering Trees, Shrubs & Plants at Approx 12 noon. LIVESTOCK SALE CENTRE BIO-SECURITY MEASURES Purchasers are requested to wear clean footwear and clothes when attending the sale. All livestock vehicles should be fully cleaned and disinfected before coming to the Market Site. METHOD OF SALE All Cattle, Sheep, Goats, Pigs, Horses & Poultry will be sold in £’s (pounds) and strictly in catalogue order, unless any alteration is authorised and announced by the Auctioneers. All Poultry will be subject to 10% Buyers Premium. CONDITIONS OF SALE The sale is held subject to the Auctioneer's General terms and Conditions of Sale and to the Auction Conditions of Sale recommended for use at Markets by the Livestock Auctioneers Association. These Conditions will be displayed in full at the Sale Premises. CATALOGUE ENTRIES Whilst every effort has been made to ensure that the descriptions are accurate no guarantee is given or implied. Buyers should note that lots may be withdrawn and other lots added prior to the sale day. Buyers are advised to contact the Auctioneers prior to the sale to confirm a particular lots inclusion since neither the Vendor nor the Auctioneers will be responsible for abortive expenses in respect of withdrawn lots. -
Complexin-1 Is a Biomarker of Synucleinopathy
DMM Advance Online Articles. Posted 20 January 2017 as doi: 10.1242/dmm.028035 Access the most recent version at http://dmm.biologists.org/lookup/doi/10.1242/dmm.028035 BLOOD RNA BIOMARKERS IN PRODROMAL PARK4 AND REM SLEEP BEHAVIOR DISORDER SHOW ROLE OF COMPLEXIN-1 LOSS FOR RISK OF PARKINSON’S DISEASE Suna Lahut1,2, Suzana Gispert1, Özgür Ömür1,2, Candan Depboylu3, Kay Seidel4, Jorge Antolio Domínguez-Bautista1, Nadine Brehm1, Hülya Tireli5, Karl Hackmann6, Caroline Pirkevi2, Barbara Leube7, Vincent Ries3, Kerstin Reim8, Nils Brose8, Wilfred F. den Dunnen9, Madrid Johnson10, Zsuzsanna Wolf11, Marc Schindewolf12, Wiebke Schrempf13, Kathrin Reetz14, Peter Young15, David Vadasz3, Achilleas S. Frangakis10, Evelin Schröck6, Helmuth Steinmetz1, Marina Jendrach1, Udo Rüb4, Ayşe Nazlı Başak2¶, Wolfgang Oertel3¶, Georg Auburger1¶ 1Exp. Neurology, Goethe University Medical School, 60590 Frankfurt/Main, Germany; 2NDAL, Boğaziçi University, 34342 Istanbul, Turkey; 3Dept. of Neurology, Philipps University, Baldingerstrasse, 35043 Marburg, Germany; 4Dr. Senckenberg Chronomedical Institute, Goethe University, 60590 Frankfurt/Main, Germany; 5Dept. of Neurology, Haydarpaşa Numune Training and Research Hospital, 34668 Istanbul, Turkey; 6Institute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany; 7Institute of Human Genetics, Heinrich Heine University, 40225 Düsseldorf, Germany; 8Dept. of Molecular Neurobiology and Center for the Molecular Physiology of the Brain, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany; 9Dept. of Pathology and Medical Biology, Medical Center, University, 9700 RB Groningen, Netherlands; 10Institut für Biophysik and Frankfurt Institute for Molecular Life Sciences, Goethe University, 60438 Frankfurt/Main, Germany; 11Hemophilia Centre, Medical Clinic III, Institute of Transfusion Medicine and Immunhematology Goethe University, 60590 Frankfurt/Main, Germany; 12Dept. -
St Kilda World Heritage Site Management Plan 2012–17 Title Sub-Title Foreword
ST KILDA World Heritage Site Management Plan 2012–17 TITLE Sub-title FOREWORD We are delighted to be able to present the revised continuing programme of research and conservation. Management Plan for the St Kilda World Heritage Site The management of the World Heritage Site is, for the years 2012-2017. however, a collaborative approach also involving partners from Historic Scotland, Scottish Natural St Kilda is a truly unique place. The spectacular Heritage, Comhairle nan Eilean Siar and the Ministry of scenery and wildlife, both on land and in the seas Defence. As custodians of St Kilda, all of the partners surrounding the islands, the archipelago’s isolation and should be thanked for their excellent work over recent inaccessibility, and the evidence, abundant for all to years, and the new Management Plan will continue to see, of the people that made these islands their home, build on these efforts. make St Kilda truly exceptional. The very nature of St Kilda means that the challenges In this respect, St Kilda showcases Scotland to the are different to those of other World Heritage Sites. world by displaying the most important features of our By identifying and addressing key short and medium heritage, our rich natural and cultural traditions, and our term issues around protection, conservation and awe inspiring landscapes and scenery. management, the Management Plan aims to embrace these challenges, and sets out a thirty year vision for the It is therefore of no surprise that St Kilda has been property, ensuring that the longer-term future of St Kilda designated as a World Heritage Site for both its cultural is properly considered. -
Single-Cell RNA-Seq of Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic
bioRxiv preprint doi: https://doi.org/10.1101/148049; this version posted August 31, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 Single-cell RNA-seq of dopaminergic neurons informs candidate gene selection for sporadic 2 Parkinson's disease 3 4 Paul W. Hook1, Sarah A. McClymont1, Gabrielle H. Cannon1, William D. Law1, A. Jennifer 5 Morton2, Loyal A. Goff1,3*, Andrew S. McCallion1,4,5* 6 7 1McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of 8 Medicine, Baltimore, Maryland, United States of America 9 2Department of Physiology Development and Neuroscience, University of Cambridge, 10 Cambridge, United Kingdom 11 3Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, 12 Maryland, United States of America 13 4Department of Comparative and Molecular Pathobiology, Johns Hopkins University School of 14 Medicine, Baltimore, Maryland, United States of America 15 5Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, 16 United States of America 17 *, To whom correspondence should be addressed: [email protected] and [email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/148049; this version posted August 31, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. -
Unworked Crofts in His Article in This Issue of the Crofter
Scottish Crofting Federation THE CROFTER rooted in our communities SCF is the only organisation solely dedicated to campaigning for crofters and fighting for the future of crofting NOVEMBER 2017 Number 113 Conflict between two endangered species: crofters and geese © Martin Benson – Skye HE UISTS HAVE had a problem with wild population returns to its former numbers. crofters on the machair. And the geese seem to geese damaging crops and grazings for The barnacle population in Uist is escalating. be winning.” Tmany years now. Last year it was 4,000, this year 8,000, next SCF has been fighting for the control of wild The main culprit was the greylag but this is year? It has been predicted that if they are not geese on croft land for many years, with a petition now being overtaken by the Greenland barnacle controlled now, crofting will stop within 10 years. in the Scottish Parliament urging the government goose. The greylags were fairly well controlled in The repercussions will last for generations, to not cut the budget, and the goose issue being an adaptive management pilot scheme run by with some of Europe’s finest high nature value regularly brought to the Cross Party Group on SNH but, despite its success, the scheme has farmland, the esteemed machair habitat, being Crofting. This parliamentary group recently wrote closed. Was this a good investment of £294,858 left to degenerate. As SCF chair Russell Smith to cabinet secretary for environment Roseanna public money? Yes, if you look at the success; no, said recently, “We have a conflict between two if the scheme does not continue and the greylag endangered species – barnacle geese and ...Continued on page 3 Scottish upland sheep INSIDE THIS ISSUE • Crofting law support shenanigans consultation HE SCOTTISH UPLAND differential needed for those crofting to actual replacements. -
Complaint Report
EXHIBIT A ARKANSAS LIVESTOCK & POULTRY COMMISSION #1 NATURAL RESOURCES DR. LITTLE ROCK, AR 72205 501-907-2400 Complaint Report Type of Complaint Received By Date Assigned To COMPLAINANT PREMISES VISITED/SUSPECTED VIOLATOR Name Name Address Address City City Phone Phone Inspector/Investigator's Findings: Signed Date Return to Heath Harris, Field Supervisor DP-7/DP-46 SPECIAL MATERIALS & MARKETPLACE SAMPLE REPORT ARKANSAS STATE PLANT BOARD Pesticide Division #1 Natural Resources Drive Little Rock, Arkansas 72205 Insp. # Case # Lab # DATE: Sampled: Received: Reported: Sampled At Address GPS Coordinates: N W This block to be used for Marketplace Samples only Manufacturer Address City/State/Zip Brand Name: EPA Reg. #: EPA Est. #: Lot #: Container Type: # on Hand Wt./Size #Sampled Circle appropriate description: [Non-Slurry Liquid] [Slurry Liquid] [Dust] [Granular] [Other] Other Sample Soil Vegetation (describe) Description: (Place check in Water Clothing (describe) appropriate square) Use Dilution Other (describe) Formulation Dilution Rate as mixed Analysis Requested: (Use common pesticide name) Guarantee in Tank (if use dilution) Chain of Custody Date Received by (Received for Lab) Inspector Name Inspector (Print) Signature Check box if Dealer desires copy of completed analysis 9 ARKANSAS LIVESTOCK AND POULTRY COMMISSION #1 Natural Resources Drive Little Rock, Arkansas 72205 (501) 225-1598 REPORT ON FLEA MARKETS OR SALES CHECKED Poultry to be tested for pullorum typhoid are: exotic chickens, upland birds (chickens, pheasants, pea fowl, and backyard chickens). Must be identified with a leg band, wing band, or tattoo. Exemptions are those from a certified free NPIP flock or 90-day certificate test for pullorum typhoid. Water fowl need not test for pullorum typhoid unless they originate from out of state. -
ACE Appendix
CBP and Trade Automated Interface Requirements Appendix: PGA August 13, 2021 Pub # 0875-0419 Contents Table of Changes .................................................................................................................................................... 4 PG01 – Agency Program Codes ........................................................................................................................... 18 PG01 – Government Agency Processing Codes ................................................................................................... 22 PG01 – Electronic Image Submitted Codes .......................................................................................................... 26 PG01 – Globally Unique Product Identification Code Qualifiers ........................................................................ 26 PG01 – Correction Indicators* ............................................................................................................................. 26 PG02 – Product Code Qualifiers ........................................................................................................................... 28 PG04 – Units of Measure ...................................................................................................................................... 30 PG05 – Scientific Species Code ........................................................................................................................... 31 PG05 – FWS Wildlife Description Codes ........................................................................................................... -
Introgression and the Fate of Domesticated Genes in a Wild Mammal
Adaptive Admixture in Soay Sheep 1 1 Introgression and the Fate of Domesticated Genes in a Wild Mammal This is the peer reviewed version of the following article: Feulner PGD, Gratten J, Kijas JW, Visscher 2 Population PM, Pemberton JM & Slate J (2013) Introgression and the fate of domesticated genes in a wild mammal population. Molecular Ecology 22: 4210–4221, which has been published in final form at 10.1111/mec.12378. This article may be used for non-commercial purposes in accordance with 3 Wiley Terms and Conditions for self-archiving. 4 Philine G.D. Feulner*1,2, Jacob Gratten*1,3, James W. Kijas4, Peter M. Visscher1,5, Josephine 5 M. Pemberton6, Jon Slate1 6 *joint first authors 7 8 1 Department of Animal and Plant Sciences, University of Sheffield, Sheffield, S10 2TN, UK 9 2 Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, 24306 Ploen, 10 Germany 11 3 The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia 12 4 Livestock Industries, CSIRO, Brisbane, Australia 13 5 The University of Queensland Diamantina Institute, Brisbane, Queensland, Australia 14 6 Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, 15 Edinburgh, EH9 3JT, UK 16 17 Keywords: admixture; adaptive introgression; Soay sheep; domesticated alleles; natural 18 selection 19 20 Corresponding author: 21 Philine Feulner 22 Max Planck Institute for Evolutionary Biology 23 August-Thienemann-Str. 2 24 24306 Plön 1 Adaptive Admixture in Soay Sheep 2 25 Germany 26 Tel: +49 (0) 4522 763-228 27 Fax: +49 (0) 4522 763-310 28 [email protected] 29 2 Adaptive Admixture in Soay Sheep 3 30 Abstract 31 When domesticated species are not reproductively isolated from their wild relatives, the opportunity 32 arises for artificially selected variants to be re-introduced into the wild. -
Dysregulation of Post-Transcriptional Modification by Copy Number
Yoshikawa et al. Translational Psychiatry (2021) 11:331 https://doi.org/10.1038/s41398-021-01460-1 Translational Psychiatry ARTICLE Open Access Dysregulation of post-transcriptional modification by copy number variable microRNAs in schizophrenia with enhanced glycation stress Akane Yoshikawa1,2,ItaruKushima 3,4, Mitsuhiro Miyashita 1,5,6,KazuyaToriumi 1, Kazuhiro Suzuki 1,5, Yasue Horiuchi 1, Hideya Kawaji 7, Shunya Takizawa8,NorioOzaki 3, Masanari Itokawa1 and Makoto Arai 1 Abstract Previously, we identified a subpopulation of schizophrenia (SCZ) showing increased levels of plasma pentosidine, a marker of glycation and oxidative stress. However, its causative genetic factors remain largely unknown. Recently, it has been suggested that dysregulated posttranslational modification by copy number variable microRNAs (CNV-miRNAs) may contribute to the etiology of SCZ. Here, an integrative genome-wide CNV-miRNA analysis was performed to investigate the etiology of SCZ with accumulated plasma pentosidine (PEN-SCZ). The number of CNV-miRNAs and the gene ontology (GO) in the context of miRNAs within CNVs were compared between PEN-SCZ and non-PEN-SCZ groups. Gene set enrichment analysis of miRNA target genes was further performed to evaluate the pathways affected in PEN-SCZ. We show that miRNAs were significantly enriched within CNVs in the PEN-SCZ versus non-PEN-SCZ groups (p = 0.032). Of note, as per GO analysis, the dysregulated neurodevelopmental events in the two groups may have different origins. Additionally, gene set enrichment analysis of miRNA target genes revealed that miRNAs involved in glycation/oxidative stress and synaptic neurotransmission, especially glutamate/GABA receptor signaling, fi 1234567890():,; 1234567890():,; 1234567890():,; 1234567890():,; were possibly affected in PEN-SCZ.