PPIL1 Antibody Cat. No.: 58-701

PPIL1 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse

This PPIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic IMMUNOGEN: peptide between 63-91 amino acids from the Central region of human PPIL1.

TESTED APPLICATIONS: WB

APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 18 kDa WEIGHT:

Properties

This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

September 30, 2021 1 https://www.prosci-inc.com/ppil1-antibody-58-701.html PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: PPIL1

ALTERNATE NAMES: Peptidyl-prolyl cis-trans isomerase-like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1

ACCESSION NO.: Q9Y3C6

PROTEIN GI NO.: 20177874

GENE ID: 51645

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of BACKGROUND: HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

REFERENCES: 1) Wang, X., et al. J. Biol. Chem. 285(7):4951-4963(2010)

2) Xu, C., et al. J. Biol. Chem. 281(23):15900-15908(2006)

3) Xu, C., et al. J. Biomol. NMR 31(2):179-180(2005)

4) Mungall, A.J., et al. Nature 425(6960):805-811(2003)

ANTIBODIES FOR RESEARCH USE ONLY.

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September 30, 2021 2 https://www.prosci-inc.com/ppil1-antibody-58-701.html