Nasal cavity Oral cavity Nostril Pharynx
Larynx
Trachea
Left main Right main (primary) (primary) bronchus bronchus Left lung Right lung
Diaphragm
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Cribriform plate of ethmoid bone Sphenoidal sinus Frontal sinus Posterior nasal aperture Nasal cavity • Nasal conchae (superior, Nasopharynx middle, and inferior) • Pharyngeal tonsil • Nasal meatuses (superior, middle, and inferior) • Opening of pharyngotympanic • Nasal vestibule tube • Nostril • Uvula Hard palate Oropharynx • Palatine tonsil Soft palate
• Lingual tonsil Tongue
Laryngopharynx Hyoid bone
Larynx Esophagus • Epiglottis • Thyroid cartilage Trachea • Vocal fold • Cricoid cartilage (b) Detailed anatomy of the upper respiratory tract © 2018 Pearson Education, Inc. 2 Pharynx • Nasopharynx • Oropharynx • Laryngopharynx
(a) Regions of the pharynx
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Posterior Mucosa
Esophagus Submucosa Trachealis Lumen of Seromucous muscle trachea gland in submucosa Hyaline cartilage Adventitia (a) Anterior © 2018 Pearson Education, Inc. 4 Intercostal muscle Rib Parietal pleura Lung Pleural cavity Trachea Visceral pleura Thymus
Apex of lung Left superior lobe Right superior lobe Oblique Horizontal fissure fissure Right middle lobe Left inferior lobe Oblique fissure Right inferior lobe Heart (in pericardial cavity of mediastinum) Diaphragm Base of lung (a) Anterior view. The lungs flank mediastinal structures laterally.
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Posterior Vertebra Esophagus (in posterior mediastinum) Root of lung at hilum Right lung • Left main bronchus Parietal pleura • Left pulmonary artery • Left pulmonary vein Visceral pleura
Pleural cavity Left lung Thoracic wall Pulmonary trunk Pericardial membranes Heart (in mediastinum) Sternum Anterior mediastinum Anterior (b) Transverse section through the thorax, viewed from above
© 2018 Pearson Education, Inc. 6 Alveolar duct Alveoli
Respiratory bronchioles Alveolar duct
Terminal bronchiole Alveolar sac
(a) Diagrammatic view of respiratory bronchioles, alveolar ducts, and alveoli
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Alveolar duct Alveolar pores
Alveolus
(b) Light micrograph of human lung tissue, showing the final divisions of the respiratory tree (120×)
© 2018 Pearson Education, Inc. 8 Red blood cell Endothelial cell nucleus Capillary
Alveolar pores
Capillary O2 CO2 Macrophage Alveolus Nucleus of squamous epithelial cell Respiratory Alveolar epithelium membrane Fused basement membranes Capillary endothelium Alveoli Red blood Surfactant- Squamous (gas-filled cell in secreting cell epithelial cell air spaces) capillary of alveolar wall
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Changes in anterior-posterior and Changes in lateral superior-inferior dimensions dimensions
Ribs are elevated as external intercostals contract External Full inspiration intercostal (External muscles intercostals contract)
Diaphragm moves inferiorly during contraction (a) Inspiration: Air (gases) flows into the lungs
© 2018 Pearson Education, Inc. 10 Changes in anterior-posterior and Changes in lateral superior-inferior dimensions dimensions
Ribs are depressed as external intercostals relax
Expiration External intercostal (External muscles intercostals relax)
Diaphragm moves superiorly as it relaxes (b) Expiration: Air (gases) flows out of the lungs © 2018 Pearson Education, Inc. 11
+2 Inspiration Expiration
Intrapulmonary +1 pressure
0
–1 Pressure relative Pressure –2 toatmospheric pressure (a) Volume of breath 0.5
0 Volume (L)
–0.5 (b) © 2018 Pearson Education, Inc. 12 6,000
5,000 Inspiratory reserve volume 4,000 3,100 ml Vital capacity 3,000 4,800 ml Total lung Tidal volume 500 ml capacity
Milliliters (ml) Expiratory 6,000 ml 2,000 reserve volume 1,200 ml 1,000 Residual volume 1,200 ml 0
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© 2018 Pearson Education, Inc. 14 Inspired air: Alveoli of lungs:
CO2 O2 O2 CO2 O2 CO2
External respiration
Pulmonary Alveolar Pulmonary arteries capillaries veins
Blood Blood leaving leaving tissues and lungs and entering entering lungs: tissue capillaries:
Heart
O2 CO2 O2 CO2 Tissue capillaries Systemic Systemic veins arteries
Internal respiration CO2 O2
Tissue cells:
O2 CO2 © 2018 Pearson Education, Inc. 15
(a) External respiration in the lungs (pulmonary gas exchange)
Oxygen is loaded into the blood, and carbon dioxide is unloaded.
Alveoli (air sacs)
O2 CO2
Loading
of O2 Unloading of CO2
Hb + O HbO - + 2 2 HCO3 + H H2CO3 CO2 + H2O (Oxyhemoglobin Bicar- Carbonic Water is formed) bonate acid ion Plasma
Red blood cell
Pulmonary capillary © 2018 Pearson Education, Inc. 16 (b) Internal respiration in the body tissues (systemic capillary gas exchange)
Oxygen is unloaded and carbon dioxide is loaded into the blood.
Tissue cells
CO2 O2
Loading Unloading of CO2 of O2
+ - CO2 + H2O H2CO3 H + HCO3 Water Carbonic Bicar- acid bonate HbO2 Hb + O2 Plasma ion
Systemic capillary
Red blood cell
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Breathing control centers: • Pons centers • Medulla centers
Afferent Efferent nerve impulses from impulses to medulla trigger contraction of medulla inspiratory muscles: • Phrenic nerves • Intercostal nerves Breathing control centers stimulated by:
+ CO2 and H increase Nerve impulse in tissue. from O sensor Intercostal 2 muscles indicating O2 decrease Diaphragm
O2 sensor in aortic body of aortic arch
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