The 29Th Annual Cleveland Review of Rheumatic Diseases a Comprehensive Review of Emerging and Controversial Topics in Rheumatology

Elisheva Weinberger, DO Director, MHSsiteHubResearchCapacityCWRUCTSC Director MHSClinicalTrials/Research Unit Professor ofMedicineandPediatrics Nora G.Singer, MD Director, SpondyloarthritisCenter, TheMetroHealthSystem Director, Fellowship Medicine Associate Professor, CaseWestern ReserveUniversitySchoolof Marina Magrey, MD Division ofRheumatology, TheMetroHealthSystem Professor EmeritusofMedicine,CaseWestern ReserveUniversity Muhammed AsimKhan,MD Division ofRheumatology, TheMetroHealthSystem Medical Director, Access Assistant ProfessorofMedicine,CaseWestern ReserveUniversity Raymond Hong,MD,MBA Department ofBiology, CaseWestern ReserveUniversity The MetroHealthSystemInvestigatoratSkeletalResearchCenter, Director, PediatricRheumatologyandBoneHealthProgram, Associate ProfessorofPediatrics,CaseWestern ReserveUniversity Hulya Bukulmez,MD University, TheMetroHealthSystem Director, LupusClinic.ProfessorofMedicine,CaseWestern Reserve Stanley Ballou,MD University, TheMetroHealthSystem Professor ofMedicineandPathology, CaseWestern Reserve Donald Anthony, MD,PhD Division ofRheumatology, TheMetroHealth System Reserve University Medicine, CaseWestern Assistant Professorof Maria Antonelli,MD RHEUMATOLOGY DIVISION OF METROHEALTH FACULTY Director, MSKUltrasound, TheMetroHealthSystem Associate Professor ofMedicine,Case Western ReserveUniversity Cheung Yue, MD Division ofRheumatology, TheMetroHealthSystem Pittsburgh, RheumatologyFellowshipTraining Program Associate ProgramDirector, DepartmentofMedicine, Universityof Mehret BirruTalabi, MD,PhD Valley, CA Rheumatology StanfordUniversitySchoolofMedicine,Portola Adjunct ClinicalProfessor, DivisionofImmunology and Vibeke Strand,MD,MACR,FACP School ofMedicine Associate ProfessorofMedicine,CaseWestern ReserveUniversity Schilz,DO,PhD Robert Effectiveness ResearchandEducation for EducationandResearchonTherapeuticsCenterOutcomes Rheumatology Vice Chair, Departmentof Medicine,Director, Center Jane KnightLoweProfessor, DivisionofClinicalImmunologyand Professor ofMedicine,UniversityAlabamaatBirmingham Kenneth G.Saag,MD,MSC Center Director, ClinicalResearchUnit,UniversityofRochesterMedical Chief, Allergy/ImmunologyandRheumatology Professor, DepartmentofMedicine Christopher T. Ritchlin,MD,MPH and DepartmentofCellBiologyattheLernerResearchInstitute Associate ProfessorofMedicine,CaseWestern ReserveUniversity Rula Hajj-Ali,MD University, ClevelandClinic Clinical Instructor, DepartmentofMedicine,CaseWestern Reserve Cassandra Calabrese,DO GUEST FACULTY Elisheva Weinberger, DO Raymond Hong,MD Cheung Yue, MD Donald Anthony, MD Muhammad Khan,MD Stanley Ballou,MD MariaAntonelli,MD Nora G.Singer, MD Marina Magrey, MD,Chair COMMITTEE CONFERENCE PLANNING Steve Ostrolencki Brenda Carter Ashley Thomas Kim Montgomery PROFESSIONALS CONFERENCE

MetroHealth 2500 MetroHealth Drive Cleveland, OH 44109-1998

MetroHealth’s Division of Rheumatology and Cleveland Society of Rheumatology Presents: The 29th Annual Cleveland Review of Rheumatic Diseases A Comprehensive Review of Emerging and Controversial Topics in Rheumatology

Friday, April 3 and Saturday, April 4, 2020 Cleveland Marriott Downtown at Key Tower 1360 W Mall Dr., Cleveland, OH 44114 Review ofRheumaticDiseases Friday, April3andSaturday, April4,2020 A Comprehensive Review of Emerging and A ComprehensiveReviewofEmergingand The 29 metrohealth.org/rheumatic-review Controversial Topics inRheumatology MetroHealth’s DivisionofRheumatologyand Cleveland SocietyofRheumatologyPresents: Cleveland MarriottDowntownatKeyTower 1360 WMallDr., Cleveland,OH44114 th Register Today! Annual Cleveland AnnualCleveland

AGENDA GENERAL INFORMATION

OBJECTIVES OF CONFERENCE Before March 3, 2020 After March 3, 2020 FRIDAY, APRIL 3, 2020 4:00 – 5:00 p.m. Complex Rheumatic Cases Cheung Cho Yue, MD; Maria Antonelli, MD; At the conclusion of these activities attendees should be able to: Cleveland Society $175.00 $250.00 7:00 – 7:45 a.m. Registration / Continental Breakfast and Raymond Hong, MD, MBA 1. Describe the recent advances of targeted biological /cellular therapies Physicians $275.00 $350.00 7:45 – 8:00 a.m. Welcoming Remarks 5:00 – 5:15 p.m. Wrap up of first day in rheumatoid arthritis and in systemic lupus erythematosus, Corporate $400.00 $475.00 particularly in terms of treatment efficacy and toxicity 5:15 p.m. Reception SESSION I: Emerging Therapeutics in Rheumatoid Arthritis MetroHealth Alumni $175.00 $250.00 Moderator: Marina N. Magrey, MD 2. Understand the recent updates in pathogenesis of lupus, and gout with bettering understanding of new targeted therapies Allied $175.00 $250.00 8:00 – 8:40 a.m. Opening Lecture Precision Medicine SATURDAY, APRIL 4, 2020 3. Describe chronic viral infections that are associated with rheumatic Fellow/ Resident FREE FREE Christopher T Ritchlin, MD, MPH 7:30 – 8:30 a.m. Registration/Continental Breakfast disease and identify those that may be prevented by existing vaccines; 8:40 – 9:15 a.m. Beyond Anti-TNF Therapy – New Biologics 4. Present strategies and safe treatments to control arthritis and SESSION V: Uncertainty in Rheumatology LOCATION and Small Molecules in Rheumatoid Arthritis arthritis related disorders during pregnancy DOWNTOWN Vibeke Strand, MD Moderator: Maria Antonelli, MD Cleveland Marriott . CLEVELAND 5. Recognize axial spondyloarthritis and distinguish it from other Downtown at Key Tower 9:15 – 9:50 a.m. Stem Cell Therapy, What do we know? 8:30 – 9:10 a.m. Vaccination in Immunosuppressed Patients disorders mimicking sacroiliitis 1360 W Mall Dr. SHOREWAY Nora G Singer, MD Cassandra Calabrese, DO 2 6. Update the recent advances about Biologic DMARD use in uveitis; Cleveland, OH 44114 E. 9TH ST 9:50 – 10:00 a.m. Panel discussion 9:10 – 9:50 a.m. Management of Rheumatic Disease 7. Identify primary and secondary lung manifestations associated with in Pregnancy LAKESIDE AVE. 10:00 – 10:15 a.m. Break and exhibits rheumatic disease and how to monitor the diseases and their therapies HOTEL Mehret Birru Talabi, MD, PhD 8. Identify newer treatments available for osteoporosis and duration of ACCOMMODATIONS ST. CLAIR AVE. 9:50 – 10:15 a.m. Panel discussion SESSION II: Emerging Therapeutics in treatment. A block of rooms has been ROCKWELL other Rheumatic Diseases 10:15 – 10:30 a.m. Break reserved at the Cleveland SUPERIOR AVE. Moderator: Raymond Hong, MD, MBA Marriott Downtown at Key ONTARIO ST ONTARIO TARGET AUDIENCE E. 12TH ST E. 13TH ST 10:30 – 11:10 a.m. Viral Rheumatic Disease T. T. Tower Hotel. S S 10:15 – 10:50 a.m. What is New in Vasculitis? Donald Anthony, MD, PhD This comprehensive review is directed to H T H 7 T Rula Hajj-Ali, MD rheumatologists, primary care physicians, 8 11:10 – 11:50 a.m. Transitioning Care from Pediatrics To make your reservation, HURON . 1 EUCLID E . 1 rheumatology fellows, nurses and allied PROSPECT E 10:50 – 11:25 a.m. Treatment of Gout-ACR Guidelines to Adult Rheumatology contact the Hotel ONTARIOBOLIVAR ST AVE. Hulya Bukulmez, MD health care professionals. Reservations Department . Kenneth Saag, MD, MSC AVE. 1-888-236-2427. Please 11:50 a.m. – 12:00 p.m. Panel Discussion 11:25 a.m. – 12:00 p.m. Emerging Therapies in Lupus Nephritis ACCREDITATION identify yourself as being Stanley Ballou, MD with the Cleveland Review E. 9TH ST Physician 12:00 – 12:15 p.m. of Rheumatic Disease Panel discussion 12:00 p.m. The MetroHealth System is accredited by the Ohio State Medical Association to provide continuing 90 71 GRAPPA-SPARTAN Symposium Conference. TO 12:15 – 1:15 p.m. Lunch medical education for physicians. The MetroHealth System designates this educational activity for HOPKINS 12:00 – 12:30 p.m. Registration and Lunch a maximum of 11.5 AMA PRA Category 1 credits. Physicians should only claim credit commensurate AIRPORT with the extent of their participation in the activity. RATE: $132.00 per night. SESSION III: Bone Disease and Spondyloarthritis 12:30 – 12:40 p.m. Pre- Test Quiz and Current Treatment for Osteoporosis Muhammed Khan, MD, Case Western Reserve University, Cleveland Faculty Disclosure The MetroHealth System has implemented a policy to comply with the current Accreditation GROUND Moderator: Stanley Ballou, MD 12:40 – 1:10 p.m. Pathogenesis and Genetics of Axial SpA and PsA Council for Continuing Medical Education standards for Commercial Support requiring resolution of TRANSPORTATION Nigel Haroon, MD,PhD, University of Toronto 1:15 – 1:50 p.m. What is new in Osteoporosis? all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified Taxi service is available from Cleveland Hopkins International Airport to in the activity syllabus. Kenneth Saag, MD, MSC 1:10 – 1:40 p.m. Screening Assessment in Axial SpA the Cleveland Marriott Downtown at Key Tower. Marina Magrey, MD, Case Western Reserve University, Cleveland Americans with Disabilities Act 1:50 – 2:25 p.m. Acute Anterior Uveitis, Causes and Treatment The MetroHealth System fully intends to comply with the legal requirements of the Americans with 1:40- 2:10 p.m. Co-morbidities in AxSpA and PsA REGISTRATION AND CANCELLATION Muhammad Khan, MD, FRCP, MACAP Disabilities Act. If you need assistance, please notify us at least two weeks prior to the activity. Elaine Husni, MD, MPH, Cleveland Clinic Preregistrations are accepted online until 7 a.m. ET April 1, 2020. In case 2:25 – 3:00 p.m. Spondyloarthritis Mimics Spartan Group Accreditation of cancellation, a partial refund will be made if cancelled by March 20, Marina N. Magrey, MD 2:10 – 2:30 p.m. Break This activity has been planned and implemented in accordance with the Essential Areas and policies 2020. NO REFUNDS WILL BE ISSUED AFTER March 27, 2020. of the Accreditation Council for Continuing Medical Education through the joint providership of 3:00 – 3:15 p.m. Panel discussion 2:30 – 3:15 p.m. Update on treatment of AxSpA Atul Deodhar, MD, MRCP, FACP, OHSU, Portalnd Oregon Health & Science University School of Medicine and NW Arthritis & Osteoporosis Institute. 3:15 – 3:30 p.m. Break and exhibits The OHSU School of Medicine is accredited by the ACCME to provide continuing medical education PARKING 3:15 – 4:00 p.m. Update on treatment of PsA for physicians. Credit: OHSU School of Medicine designates this live activity for a maximum of 3.0 Valet parking is $35.00 daily and $18.00 for the event only. Siba Raychaudhuri, MD, University of California Davis AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent SESSION IV: Clinical Conundrums in Rheumatology of their participation in the activity. Self parking $16.00 up to 12 hours and $25.00 for 12-24 hours. Saturday Moderator, Elisha Weinberger, MD 4:00 – 4:20 p.m. Post Test Quiz and Sunday is $10.00. Muhammad Khan, MD 3:30 – 4:00 p.m. Interstitial Lung Disease in Rheumatic Diseases Robert Schilz, DO, PhD 4:20 p.m. Adjourn Register Today! metrohealth.org/rheumatic-review