FGFBP1 Conjugated Antibody

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Product Datasheet FGFBP1 Conjugated Antibody Catalog No: #C43473 Package Size: #C43473-AF350 100ul #C43473-AF405 100ul #C43473-AF488 100ul Orders: [email protected] Support: [email protected] #C43473-AF555 100ul #C43473-AF594 100ul #C43473-AF647 100ul #C43473-AF680 100ul #C43473-AF750 100ul #C43473-Biotin 100ul Description Product Name FGFBP1 Conjugated Antibody Host Species Rabbit Clonality Polyclonal Species Reactivity Hu Specificity The antibody detects endogenous levels of total FGFBP1 protein. Immunogen Description Synthetic peptide of human FGFBP1 Conjugates Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750 Other Names FGFBP; HBP17; FGF-BP; FGF-BP1; FGFBP-1 Accession No. Swiss-Prot#:Q14512NCBI Gene ID:9982NCBI mRNA#:NP_005121NCBI Protein#: Calculated MW 26KD Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide Storage Store at 4°Cin dark for 6 months Application Details Suggested Dilution: AF350 conjugated: most applications: 1: 50 - 1: 250 AF405 conjugated: most applications: 1: 50 - 1: 250 AF488 conjugated: most applications: 1: 50 - 1: 250 AF555 conjugated: most applications: 1: 50 - 1: 250 AF594 conjugated: most applications: 1: 50 - 1: 250 AF647 conjugated: most applications: 1: 50 - 1: 250 AF680 conjugated: most applications: 1: 50 - 1: 250 AF750 conjugated: most applications: 1: 50 - 1: 250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000 Background This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Note: This product is for in vitro research use only and is not intended for use in humans or animals. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2.

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Human FGFBP1 ELISA Kit (ARG82056)
Product datasheet [email protected] ARG82056 Package: 96 wells Human FGFBP1 ELISA Kit Store at: 4°C Summary Product Description Human FGFBP1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human FGFBP1 in serum, plasma and cell culture supernatants. Tested Reactivity Hu Tested Application ELISA Target Name FGFBP1 Conjugation HRP Conjugation Note Substrate: TMB and read at 450 nm. Sensitivity 11.7 pg/ml Sample Type Serum, plasma and cell culture supernatants. Standard Range 23.4 - 1500 pg/ml Sample Volume 100 µl Alternate Names Fibroblast growth factor-binding protein 1; 17 kDa heparin-binding growth factor-binding protein; FGF- BP; FGF-binding protein 1; HBp17; FGFBP; 17 kDa HBGF-binding protein; FGFBP-1; HBP17; FGF-BP1 Application Instructions Assay Time 4.5 hours Properties Form 96 well Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. Note For laboratory research only, not for drug, diagnostic or other use. Bioinformation Gene Symbol FGFBP1 Gene Full Name fibroblast growth factor binding protein 1 Background This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma.
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Discovery of Resistance Pathways to Fibroblast Growth Factor Receptor Inhibition in Bladder Cancer
bioRxiv preprint doi: https://doi.org/10.1101/183293; this version posted August 31, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Discovery of Resistance Pathways to Fibroblast Growth Factor Receptor inhibition in Bladder Cancer Sumanta K Pal, Miaoling He, Jeremy O Jones Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA Running Title: FGFRi resistance in bladder cancer Corresponding Author and to whom reprint requests should be made: Jeremy Jones 1500 E Duarte Rd Beckman 2310 Duarte, CA 91010 Phone: 626-256-4673 ext 80270 Fax: 626-471-3902 Email: [email protected] Figures: 4 Total Words (Abstract Words): 3438 (218) bioRxiv preprint doi: https://doi.org/10.1101/183293; this version posted August 31, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Abstract: Background: Aberrant fibroblast growth factor receptor (FGFR) signaling drives the growth of many bladder cancers. NVP-BGJ398 is a small molecule with potent inhibitory activity of FGFRs 1, 2, and 3, and has been shown to selectively inhibit the growth of bladder cancer cell lines that over-express FGFR3 or have oncogenic FGFR3 fusions. As with many agents targeting receptor tyrosine kinases, resistance is known to develop. Objective: We sought to identify potential mechanisms of resistance to NVP-BGJ398 in cell culture models of bladder cancer. Methods: RT-112 bladder cancer cell lines were derived that were resistant to growth in 3uM NVP-BGJ398.
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Anti-FGFBP1 Antibody (ARG41185)
Product datasheet [email protected] ARG41185 Package: 100 μl anti-FGFBP1 antibody Store at: -20°C Summary Product Description Rabbit Polyclonal antibody recognizes FGFBP1 Tested Reactivity Hu, Ms, Rat Tested Application WB Host Rabbit Clonality Polyclonal Isotype IgG Target Name FGFBP1 Antigen Species Human Immunogen Recombinant fusion protein corresponding to aa. 24-234 of Human FGFBP1 (NP_005121.1). Conjugation Un-conjugated Alternate Names Fibroblast growth factor-binding protein 1; 17 kDa heparin-binding growth factor-binding protein; FGF- BP; FGF-binding protein 1; HBp17; FGFBP; 17 kDa HBGF-binding protein; FGFBP-1; HBP17; FGF-BP1 Application Instructions Application table Application Dilution WB 1:500 - 1:2000 Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. Positive Control A549 Calculated Mw 26 kDa Observed Size 30 kDa Properties Form Liquid Purification Affinity purified. Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. Preservative 0.02% Sodium azide Stabilizer 50% Glycerol Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. Note For laboratory research only, not for drug, diagnostic or other use. www.arigobio.com 1/2 Bioinformation Gene Symbol FGFBP1 Gene Full Name fibroblast growth factor binding protein 1 Background This gene encodes a secreted fibroblast growth factor carrier protein.
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Rabbit Anti-FGFBP1/FITC Conjugated Antibody
SunLong Biotech Co.,LTD Tel: 0086-571- 56623320 Fax:0086-571- 56623318 E-mail:[email protected] www.sunlongbiotech.com Rabbit Anti-FGFBP1/FITC Conjugated antibody SL1768R-FITC Product Name: Anti-FGFBP1/FITC Chinese Name: FITC标记的纤维细胞生长因子Binding protein抗体 FGF-binding protein; 17 kDa heparin binding growth factor binding protein; FGF Alias: binding protein 1; FGF BP; FGF BP1; FGF-BP; FGFBP; FGFBP1; Fibroblast growth factor binding protein 1 precursor; HBP17; FGFP1_HUMAN. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat, IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 23kDa Cellular localization: The cell membrane Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human FGFBP Lsotype: IgG Purification: affinitywww.sunlongbiotech.com purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by Product Detail: binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma.
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The Application of Mouse and Human Embryonic Stem Cells with Transcriptomics in Alternative Developmental Toxicity Tests
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bioRxiv preprint doi: https://doi.org/10.1101/378711; this version posted August 19, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 Title: 2 An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice 3 Short Title: 4 Genomic response to selection for longer limbs 5 One-sentence summary: 6 Genome sequencing of mice selected for longer limbs reveals that rapid selection response is 7 due to both discrete loci and polygenic adaptation 8 Authors: 9 João P. L. Castro 1,*, Michelle N. Yancoskie 1,*, Marta Marchini 2, Stefanie Belohlavy 3, Marek 10 Kučka 1, William H. Beluch 1, Ronald Naumann 4, Isabella Skuplik 2, John Cobb 2, Nick H. 11 Barton 3, Campbell Rolian2,†, Yingguang Frank Chan 1,† 12 Affiliations: 13 1. Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany 14 2. University of Calgary, Calgary AB, Canada 15 3. IST Austria, Klosterneuburg, Austria 16 4. Max Planck Institute for Cell Biology and Genetics, Dresden, Germany 17 Corresponding author: 18 Campbell Rolian 19 Yingguang Frank Chan 20 * indicates equal contribution 21 † indicates equal contribution 22 Abstract: 23 Evolutionary studies are often limited by missing data that are critical to understanding the 24 history of selection. Selection experiments, which reproduce rapid evolution under controlled 25 conditions, are excellent tools to study how genomes evolve under strong selection. Here we 1 bioRxiv preprint doi: https://doi.org/10.1101/378711; this version posted August 19, 2018.
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