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Bluebird Bio, Inc. (Exact Name of Registrant As Specified in Its Charter) UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2018 (June 1, 2018) bluebird bio, Inc. (Exact name of Registrant as Specified in Its Charter) DELAWARE 001-35966 13-3680878 (State or Other Jurisdiction (IRS Employer of Incorporation) (Commission File Number) Identification No.) 60 Binney Street, Cambridge, MA 02142 (Address of Principal Executive Offices) (Zip Code) Registrant’s Telephone Number, Including Area Code: (339) 499-9300 Not Applicable (Former Name or Former Address, if Changed Since Last Report) Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instructions A.2. below): ☐ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ☐ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) Indicate by check mark whether the registrant is an emerging growth company as defined in as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐ Item 7.01 Regulation FD Disclosure. On June 1, 2018, bluebird bio, Inc. (“bluebird”) will be conducting an investor webcast summarizing updated data from the CRB-401 clinical study of the bb2121 product candidate in patients with relapsed/ refractory multiple myeloma. A copy of the presentation is being furnished as Exhibit 99.1 to this Report on Form 8-K. The information in Item 7.01 of this Current Report on Form 8-K and Exhibit 99.1 attached hereto is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such filing. Item 8.01 Other Events. On June 1, 2018, bluebird issued a press release announcing updated data from the CRB-401 clinical study of the bb2121 product candidate in patients with relapsed/ refractory multiple myeloma. The full text of bluebird’s press release regarding the announcement is filed as Exhibit 99.2 to this Current Report on Form 8-K and is incorporated herein by reference. Item 9.01 Financial Statements and Exhibits. (d) Exhibits Exhibit No. Description 99.1 Investor presentation provided by bluebird bio, Inc. on June 1, 2018. 99.2 Press release issued by bluebird bio, Inc. on June 1, 2018. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Date: June 1, 2018 bluebird bio, Inc. By:/s/ Jason F. Cole Jason F. Cole Chief Legal Officer A S C O A n aly st & In v esto r Web cast Ju n e 1 , 2 0 1 8 N A S D A Q : B L U E Ju n e 1 , 2 0 1 8 E x h ib it 9 9 .1 T h es lid es an d th e aco m p an y in g o ral p resn taio n co n tain fo rw ard -lo o k in g staem en ts an d in fo rm atio n relatin g to b lu eb ird b io , itsp ro d u ct an d id ate b b 2 1 2 1 an d o n co lo g y resach an d d ev elo p m en t p lan s. 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F o rw ard L o o k in g S taem en ts Welco m e N ick L esch ly , ch ief b lu eb ird Mak in g H o p e A R eality T H E G E N E T H E R A P Y P R O D U C T S C O M P A N Y L en tiG lo b in S C D D at-D riv en A celratio n L en tiG lo b in T D T F irst F iln g (2 0 1 8 ) L en ti-D C A L D F irst F iln g (2 0 1 9 ) P atien t Im p act ∞ b b 2 1 2 1 Mu ltip le My elo m a F irst F iln g (2 0 1 9 ) P ro d u cts o n th e Mark et 2 + A d d ito n al P ro g ram s in th e C lin ic 4 + P ro g ram s N earin g C o m m ercialzto n 2 + P ath to P atien ts T h re R eg u lato ry F iln g s A n ticp ated b y E n d o f 2 0 1 9 K ey Q u estio n s fo r T o d ay Wh at m o re h av e w e larn ed ab o u t eficay an d d u rab ilty o f b b 2 1 2 1 in th is h eav ily p retad p atien t p o p u latio n ? Wh at reh e n ew learn in g s? B C MA ex p resio n ? D o se rp o n se? Ith e safty p ro file stm an ag eab le? Isth e p ath to earlin es p ro g resin g ? C R B -4 0 1 D at U p d ate D av id D av id so n , M.D ., ch ief m ed ical o ficer B aselin e D em o g rap h ics an d C lin ical C h arcteis P arm etr E scaltio n (N = 2 1 ) E x p an sio n (N = 2 2 ) Med ian (m in , m ax ) fo lo w -u p , d 3 4 5 (4 6 , 6 3 8 ) 8 7 (2 9 , 1 8 4 ) Med ian (m in , m ax ) ag e, y 5 8 (3 7 , 7 4 ) 6 5 (4 4 , 7 5 ) Male, n (% ) 1 3 (6 2 ) 1 6 (7 3 ) Med ian (m in , m ax ) tim e sin ce d iag n o si, y 4 (1 , 1 6 ) 6 (1 , 3 6 ) E C O G P S ,1 n (% ) 0 1 1 0 (4 8 ) 1 1 (5 2 ) 6 (2 7 ) 1 6 (7 2 ) H ig h -risk cy to g en etics, n (% ) d el(1 7 p ), t(4 ;1 4 ), t(1 4 ;1 6 ) 8 (3 8 ) 9 (4 1 ) E C O G , E astern C o o p erativ e O n co lo g y G ro u p s p erfo rm an ce stau s; IS S , in tern atio n al stg in g sy stem ; N A , n o t av ailb le.
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